Structural insights into the cofactor-assisted substrate recognition of yeast methylglyoxal/isovaleraldehyde reductase Gre2

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1844, Issue 9, 2014, Pages 1486-1492

  Guo, Peng Chao ^a,b   Bao, Zhang Zhi ^b   Ma, Xiao Xiao ^b   Xia, Qingyou ^a   Li, Wei Fang ^b  

^a SOUTHWEST UNIVERSITY   (China)

^b UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

Crystal structure; Enzymatic kinetics; Methylglyoxal isovaleraldehyde reductase; Saccharomyces cerevisiae; Substrate binding pocket

Indexed keywords

ALDEHYDE; GRE2 PROTEIN; HOMODIMER; ISOVALERALDEHYDE; KETONE; METHYLGLYOXAL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVITY; MOLECULAR RECOGNITION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; SACCHAROMYCES CEREVISIAE; STEREOCHEMISTRY; YEAST;

CRYSTAL STRUCTURE; ENZYMATIC KINETICS; METHYLGLYOXAL/ISOVALERALDEHYDE REDUCTASE; SACCHAROMYCES CEREVISIAE; SUBSTRATE-BINDING POCKET;

AMINO ACID SEQUENCE; APOENZYMES; COENZYMES; CRYSTALLOGRAPHY, X-RAY; KINETICS; MOLECULAR DOCKING SIMULATION; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NADP; OXIDOREDUCTASES; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN SUBUNITS; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY; THERMODYNAMICS;

EID: 84902187254     PISSN: 15709639     EISSN: 18781454     Source Type: Journal    
DOI: 10.1016/j.bbapap.2014.05.008     Document Type: Article

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