-
1
-
-
12644275745
-
Glutathione levels and sensitivity to apoptosis are regulated by changes in transaldolase expression
-
Banki K, Hutter E, Colombo E, Gonchoroff NJ, and Perl A. Glutathione levels and sensitivity to apoptosis are regulated by changes in transaldolase expression. J Biol Chem 271: 32994-33001, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 32994-33001
-
-
Banki, K.1
Hutter, E.2
Colombo, E.3
Gonchoroff, N.J.4
Perl, A.5
-
2
-
-
0033083310
-
Elevation of mitochondrial transmembrane potential and reactive oxygen intermediate levels are early events and occur independently from activation of caspases in Fas signaling
-
Banki K, Hutter E, Gonchoroff N, and Perl A. Elevation of mitochondrial transmembrane potential and reactive oxygen intermediate levels are early events and occur independently from activation of caspases in Fas signaling. J Immunol 162: 1466-1479, 1999.
-
(1999)
J Immunol
, vol.162
, pp. 1466-1479
-
-
Banki, K.1
Hutter, E.2
Gonchoroff, N.3
Perl, A.4
-
3
-
-
0026777352
-
And the Committee on Prognosis Studies in SLE. Derivation of the SLEDAI. A disease activity index for lupus patients
-
Bombardier C, Gladman DD, Urowitz MB, Caron D, Chang CH, and The Committee on Prognosis Studies in SLE. Derivation of the SLEDAI. A disease activity index for lupus patients. Arthritis Rheum 35: 630-640, 1992.
-
(1992)
Arthritis Rheum
, vol.35
, pp. 630-640
-
-
Bombardier, C.1
Gladman, D.D.2
Urowitz, M.B.3
Caron, D.4
Chang, C.H.5
-
4
-
-
84881126185
-
HRES-1/ RAB4-mediated depletion of DRP1 impairs mitochondrial homeostasis and represents a target for treatment in SLE
-
DOI: 10.1136/annrheumdis-2013-203794
-
Caza TN, Fernandez D, Talaber G, Oaks Z, Haas M, Madaio MP, Lai Z-W, Miklossy G, Singh RR, Chudakov DM, Malorni W, Middleton FA, Banki K, and Perl A. HRES-1/ RAB4-mediated depletion of DRP1 impairs mitochondrial homeostasis and represents a target for treatment in SLE. Ann Rheum Dis 2013. DOI: 10.1136/annrheumdis-2013-203794.
-
(2013)
Ann Rheum Dis
-
-
Caza, T.N.1
Fernandez, D.2
Talaber, G.3
Oaks, Z.4
Haas, M.5
Madaio, M.P.6
Lai, Z.-W.7
Miklossy, G.8
Singh, R.R.9
Chudakov, D.M.10
Malorni, W.11
Middleton, F.A.12
Banki, K.13
Perl, A.14
-
5
-
-
0032560572
-
Persistent inhibition of cell respiration by nitric oxide: Crucial role of S-nitrosylation of mitochondrial complex i and protective action of glutathione
-
Clementi E, Brown GC, Feelisch M, and Moncada S. Persistent inhibition of cell respiration by nitric oxide: crucial role of S-nitrosylation of mitochondrial complex I and protective action of glutathione. Proc Natl Acad Sci U S A 95: 7631-7636, 1998.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 7631-7636
-
-
Clementi, E.1
Brown, G.C.2
Feelisch, M.3
Moncada, S.4
-
6
-
-
0029097704
-
Protective effect of N-acetylcysteine in tumor necrosis factor-alpha-induced apoptosis in U937 cells: The role of mitochondria
-
Cossarizza A, Franceschi C, Monti D, Salvioli S, Bellesia E, Rivabene R, Biondo L, Rainaldi G, Tinari A, and Malorni W. Protective effect of N-acetylcysteine in tumor necrosis factor-alpha-induced apoptosis in U937 cells: the role of mitochondria. Exp Cell Res 220: 232-240, 1995.
-
(1995)
Exp Cell Res
, vol.220
, pp. 232-240
-
-
Cossarizza, A.1
Franceschi, C.2
Monti, D.3
Salvioli, S.4
Bellesia, E.5
Rivabene, R.6
Biondo, L.7
Rainaldi, G.8
Tinari, A.9
Malorni, W.10
-
7
-
-
84902167408
-
-
This reference has been deleted
-
This reference has been deleted.
-
-
-
-
8
-
-
28144459814
-
Highdose acetylcysteine in idiopathic pulmonary fibrosis [see comment]
-
IFIGENIA Study Group
-
Demedts M, Behr J, Buhl R, Costabel U, Dekhuijzen R, Jansen HM, MacNee W, Thomeer M, Wallaert B, Laurent F, Nicholson AG, Verbeken EK, Verschakelen J, Flower CD, Capron F, Petruzzelli S, De Vuyst P, van den Bosch JM, Rodriguez-Becerra E, Corvasce G, Lankhorst I, Sardina M, Montanari M, and IFIGENIA Study Group. Highdose acetylcysteine in idiopathic pulmonary fibrosis [see comment]. N Engl J Med 353: 2229-2242, 2005.
-
(2005)
N Engl J Med
, vol.353
, pp. 2229-2242
-
-
Demedts, M.1
Behr, J.2
Buhl, R.3
Costabel, U.4
Dekhuijzen, R.5
Jansen, H.M.6
Macnee, W.7
Thomeer, M.8
Wallaert, B.9
Laurent, F.10
Nicholson, A.G.11
Verbeken, E.K.12
Verschakelen, J.13
Flower, C.D.14
Capron, F.15
Petruzzelli, S.16
De Vuyst, P.17
Van Den Bosch, J.M.18
Rodriguez-Becerra, E.19
Corvasce, G.20
Lankhorst, I.21
Sardina, M.22
Montanari, M.23
more..
-
9
-
-
0842305108
-
Discrimination of depolarized from polarized mitochondria by confocal fluorescence resonance energy transfer
-
Elmore SP, Nishimura Y, Qian T, Herman B, and Lemasters JJ. Discrimination of depolarized from polarized mitochondria by confocal fluorescence resonance energy transfer. Arch Biochem Biophys 422: 145-152, 2004.
-
(2004)
Arch Biochem Biophys
, vol.422
, pp. 145-152
-
-
Elmore, S.P.1
Nishimura, Y.2
Qian, T.3
Herman, B.4
Lemasters, J.J.5
-
10
-
-
58749104550
-
Metabolic control of T cell activation and death in SLE
-
Fernandez D and Perl A. Metabolic control of T cell activation and death in SLE. Autoimmun Rev 8: 184-189, 2009.
-
(2009)
Autoimmun Rev
, vol.8
, pp. 184-189
-
-
Fernandez, D.1
Perl, A.2
-
11
-
-
33749345289
-
Rapamycin reduces disease activity and normalizes T-cell activationinduced calcium fluxing in patients with systemic lupus erythematosus
-
Fernandez D, Bonilla E, Mirza N, and Perl A. Rapamycin reduces disease activity and normalizes T-cell activationinduced calcium fluxing in patients with systemic lupus erythematosus. Arthritis Rheum 54: 2983-2988, 2006.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 2983-2988
-
-
Fernandez, D.1
Bonilla, E.2
Mirza, N.3
Perl, A.4
-
12
-
-
61449084536
-
Activation of mTOR controls the loss of TCR. in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation
-
Fernandez DR, Telarico T, Bonilla E, Li Q, Banerjee S, Middleton FA, Phillips PE, Crow MK, Oess S, Muller-Esterl W, and Perl A. Activation of mTOR controls the loss of TCR. in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation. J Immunol 182: 2063-2073, 2009.
-
(2009)
J Immunol
, vol.182
, pp. 2063-2073
-
-
Fernandez, D.R.1
Telarico, T.2
Bonilla, E.3
Li, Q.4
Banerjee, S.5
Middleton, F.A.6
Phillips, P.E.7
Crow, M.K.8
Oess, S.9
Muller-Esterl, W.10
Perl, A.11
-
13
-
-
67650677014
-
Pharmacotherapy of systemic lupus erythematosus
-
Francis L and Perl A. Pharmacotherapy of systemic lupus erythematosus. Expert Opin Pharmacother 10: 1481-1494, 2009.
-
(2009)
Expert Opin Pharmacother
, vol.10
, pp. 1481-1494
-
-
Francis, L.1
Perl, A.2
-
14
-
-
0036161789
-
Mitochondrial hyperpolarization and ATP depletion in patients with systemic lupus erythematosus
-
Gergely PJ, Grossman C, Niland B, Puskas F, Neupane H, Allam F, Banki K, Phillips PE, and Perl A. Mitochondrial hyperpolarization and ATP depletion in patients with systemic lupus erythematosus. Arthritis Rheum 46: 175-190, 2002.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 175-190
-
-
Gergely, P.J.1
Grossman, C.2
Niland, B.3
Puskas, F.4
Neupane, H.5
Allam, F.6
Banki, K.7
Phillips, P.E.8
Perl, A.9
-
15
-
-
0037100275
-
Persistent mitochondrial hyperpolarization, increased reactive oxygen intermediate production, and cytoplasmic alkalinization characterize altered IL-10 signaling in patients with systemic lupus erythematosus
-
Gergely PJ, Niland B, Gonchoroff N, Pullmann R Jr., Phillips PE, and Perl A. Persistent mitochondrial hyperpolarization, increased reactive oxygen intermediate production, and cytoplasmic alkalinization characterize altered IL-10 signaling in patients with systemic lupus erythematosus. J Immunol 169: 1092-1101, 2002.
-
(2002)
J Immunol
, vol.169
, pp. 1092-1101
-
-
Gergely, P.J.1
Niland, B.2
Gonchoroff, N.3
Pullmann Jr., R.4
Phillips, P.E.5
Perl, A.6
-
16
-
-
0031229830
-
Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus
-
Hochberg MC. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 40: 1725, 1997.
-
(1997)
Arthritis Rheum
, vol.40
, pp. 1725
-
-
Hochberg, M.C.1
-
17
-
-
54049146740
-
Complex i within oxidatively stressed bovine heart mitochondria is glutathionylated on Cys-531 and Cys-704 of the 75-kDa Subunit
-
Hurd TR, Requejo R, Filipovska A, Brown S, Prime TA, Robinson AJ, Fearnley IM, and Murphy MP. Complex I within oxidatively stressed bovine heart mitochondria is glutathionylated on Cys-531 and Cys-704 of the 75-kDa Subunit. J Biol Chem 283: 24801-24815, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 24801-24815
-
-
Hurd, T.R.1
Requejo, R.2
Filipovska, A.3
Brown, S.4
Prime, T.A.5
Robinson, A.J.6
Fearnley, I.M.7
Murphy, M.P.8
-
18
-
-
84865633655
-
N-acetylcysteine reduces disease activity by blocking mTOR in T cells of lupus patients
-
Lai Z-W, Hanczko R, Bonilla E, Caza TN, Clair B, Bartos A, Miklossy G, Jimah J, Doherty E, Tily H, Francis L, Garcia R, Dawood M, Yu J, Ramos I, Coman I, Faraone SV, Phillips PE, and Perl A. N-acetylcysteine reduces disease activity by blocking mTOR in T cells of lupus patients. Arthritis Rheum 64: 2937-2946, 2012.
-
(2012)
Arthritis Rheum
, vol.64
, pp. 2937-2946
-
-
Lai, Z.-W.1
Hanczko, R.2
Bonilla, E.3
Caza, T.N.4
Clair, B.5
Bartos, A.6
Miklossy, G.7
Jimah, J.8
Doherty, E.9
Tily, H.10
Francis, L.11
Garcia, R.12
Dawood, M.13
Yu, J.14
Ramos, I.15
Coman, I.16
Faraone, S.V.17
Phillips, P.E.18
Perl, A.19
-
19
-
-
38449114344
-
Pharmacological treatment of chronic obstructive pulmonary disease
-
a. Montuschi P. Pharmacological treatment of chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis 1: 409-423, 2006.
-
(2006)
Int J Chron Obstruct Pulmon Dis
, vol.1
, pp. 409-423
-
-
Montuschi, P.1
-
20
-
-
0242663915
-
T cell activation-induced mitochondrial hyperpolarization is mediated by Ca2 + - And redox-dependent production of nitric oxide
-
Nagy G, Koncz A, and Perl A. T cell activation-induced mitochondrial hyperpolarization is mediated by Ca2 + - and redox-dependent production of nitric oxide. J Immunol 171: 5188-5197, 2003.
-
(2003)
J Immunol
, vol.171
, pp. 5188-5197
-
-
Nagy, G.1
Koncz, A.2
Perl, A.3
-
21
-
-
4644247643
-
Nitric oxide-dependent mitochondrial biogenesis generates Ca2 + signaling profile of lupus T cells
-
Nagy G, Barcza M, Gonchoroff N, Phillips PE, and Perl A. Nitric oxide-dependent mitochondrial biogenesis generates Ca2 + signaling profile of lupus T cells. J Immunol 173: 3676-3683, 2004.
-
(2004)
J Immunol
, vol.173
, pp. 3676-3683
-
-
Nagy, G.1
Barcza, M.2
Gonchoroff, N.3
Phillips, P.E.4
Perl, A.5
-
22
-
-
0347579845
-
Mitochondrial biogenesis in mammals: The role of endogenous nitric oxide [comment]
-
Nisoli E, Clementi E, Paolucci C, Cozzi V, Tonello C, Sciorati C, Bracale R, Valerio A, Francolini M, Moncada S, and Carruba MO. Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide [comment]. Science 299: 896-899, 2003.
-
(2003)
Science
, vol.299
, pp. 896-899
-
-
Nisoli, E.1
Clementi, E.2
Paolucci, C.3
Cozzi, V.4
Tonello, C.5
Sciorati, C.6
Bracale, R.7
Valerio, A.8
Francolini, M.9
Moncada, S.10
Carruba, M.O.11
-
23
-
-
33746841367
-
Nitric oxide and mitochondrial biogenesis
-
Nisoli E and Carruba MO. Nitric oxide and mitochondrial biogenesis. J Cell Sci 119: 2855-2862, 2006.
-
(2006)
J Cell Sci
, vol.119
, pp. 2855-2862
-
-
Nisoli, E.1
Carruba, M.O.2
-
24
-
-
0031127933
-
Effect of late modulation of nitric oxide production on murine lupus
-
Oates JC, Ruiz P, Alexander A, Pippen AMM, and Gilkeson GS. Effect of late modulation of nitric oxide production on murine lupus. Clin Immunol Immunopathol 83: 86-92, 1997.
-
(1997)
Clin Immunol Immunopathol
, vol.83
, pp. 86-92
-
-
Oates, J.C.1
Ruiz, P.2
Alexander, A.3
Pippen, A.M.M.4
Gilkeson, G.S.5
-
25
-
-
84887171398
-
Oxidative stress in the pathology and treatment of systemic lupus erythematosus
-
Perl A. Oxidative stress in the pathology and treatment of systemic lupus erythematosus. Nat Rev Rheumatol 9: 674-686, 2013.
-
(2013)
Nat Rev Rheumatol
, vol.9
, pp. 674-686
-
-
Perl, A.1
-
26
-
-
84868528207
-
Assessment of mitochondrial dysfunction in lymphocytes of patients with systemic lupus erythematosus
-
Perl A, Hanczko R, and Doherty E. Assessment of mitochondrial dysfunction in lymphocytes of patients with systemic lupus erythematosus. Methods Mol Biol 900: 61-89, 2012.
-
(2012)
Methods Mol Biol
, vol.900
, pp. 61-89
-
-
Perl, A.1
Hanczko, R.2
Doherty, E.3
-
27
-
-
0034614897
-
Consequences of cell death: Exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells
-
Sauter B, Albert ML, Francisco L, Larsson M, Somersan S, and Bhardwaj N. Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells. J Exp Med 191: 423-434, 2000.
-
(2000)
J Exp Med
, vol.191
, pp. 423-434
-
-
Sauter, B.1
Albert, M.L.2
Francisco, L.3
Larsson, M.4
Somersan, S.5
Bhardwaj, N.6
-
28
-
-
0037160091
-
Topology of superoxide production from different sites in the mitochondrial electron transport chain
-
St Pierre J, Buckingham JA, Roebuck SJ, and Brand MD. Topology of superoxide production from different sites in the mitochondrial electron transport chain. J Biol Chem 277: 44784-44790, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 44784-44790
-
-
St Pierre, J.1
Buckingham, J.A.2
Roebuck, S.J.3
Brand, M.D.4
-
29
-
-
0035059028
-
Antioxidants suppress mortality in the female NZB x NZW F1 mouse model of systemic lupus erythematosus (SLE)
-
Suwannaroj S, Lagoo A, Keisler D, and McMurray RW. Antioxidants suppress mortality in the female NZB x NZW F1 mouse model of systemic lupus erythematosus (SLE). Lupus 10: 258-265, 2001.
-
(2001)
Lupus
, vol.10
, pp. 258-265
-
-
Suwannaroj, S.1
Lagoo, A.2
Keisler, D.3
McMurray, R.W.4
-
30
-
-
84896762116
-
HRES-1/Rab4 promotes the formation of LC3+ autophagosomes and the accumulation of mitochondria during autophagy
-
Talaber G, Miklossy G, Oaks Z, Liu Y, Tooze SA, Chudakov DM, Banki K, and Perl A. HRES-1/Rab4 promotes the formation of LC3+ autophagosomes and the accumulation of mitochondria during autophagy. PLoS One 9: e84392, 2014.
-
(2014)
PLoS One
, vol.9
-
-
Talaber, G.1
Miklossy, G.2
Oaks, Z.3
Liu, Y.4
Tooze, S.A.5
Chudakov, D.M.6
Banki, K.7
Perl, A.8
-
31
-
-
0020436689
-
The 1982 revised criteria for the classification of systemic lupus erythematosus
-
Tan EM, Cohen AS, Fries JF, Masi AT, McShane DJ, Rothfield NF, Schaller JG, Talal N, and Winchester RJ. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 25: 1271-1277, 1982.
-
(1982)
Arthritis Rheum
, vol.25
, pp. 1271-1277
-
-
Tan, E.M.1
Cohen, A.S.2
Fries, J.F.3
Masi, A.T.4
McShane, D.J.5
Rothfield, N.F.6
Schaller, J.G.7
Talal, N.8
Winchester, R.J.9
-
32
-
-
0028036257
-
The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: Increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orally administered NG-monomethyl- L-arginine
-
Weinberg JB, Granger DL, Pisetsky DS, Seldin MF, Misukonis MA, Mason SN, Pippen AM, Ruiz P, Wood ER, and Gilkeson GS. The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: Increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orally administered NG-monomethyl- L-arginine. J Exp Med 179: 651-660, 1994.
-
(1994)
J Exp Med
, vol.179
, pp. 651-660
-
-
Weinberg, J.B.1
Granger, D.L.2
Pisetsky, D.S.3
Seldin, M.F.4
Misukonis, M.A.5
Mason, S.N.6
Pippen, A.M.7
Ruiz, P.8
Wood, E.R.9
Gilkeson, G.S.10
|