Silencing of KIF14 interferes with cell cycle progression and cytokinesis by blocking the p27Kip1 ubiquitination pathway in hepatocellular carcinoma

Experimental and Molecular Medicine

Volumn 46, Issue 5, 2014, Pages

  Xu, Haidong ^a,b   Choe, Chungyoul ^a   Shin, Seung Hun ^a   Park, Sung Won ^a   Kim, Ho Shik ^a   Jung, Seung Hyun ^a   Yim, Seon Hee ^a   Kim, Tae Min ^a   Chung, Yeun Jun ^a  

^a The Catholic University of Korea   (South Korea)

^b YANBIAN UNIVERSITY   (China)

Author keywords

Cell cycle; Cytokinesis; Hepatocellular carcinoma; KIF14; Ubiquitination

Indexed keywords

BIOLOGICAL FACTOR; CARRIER PROTEINS AND BINDING PROTEINS; CKS1 PROTEIN; CYCLIN B1; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN E1; MESSENGER RNA; PROTEIN CUL1; ROC1 PROTEIN; S PHASE KINASE ASSOCIATED PROTEIN 1; S PHASE KINASE ASSOCIATED PROTEIN 2; SMALL INTERFERING RNA; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; CYCLINE; KIF14 PROTEIN, HUMAN; KINESIN; ONCOPROTEIN; PROTEASOME; S PHASE KINASE ASSOCIATED PROTEIN;

ARTICLE; CANCER INHIBITION; CELL CYCLE PROGRESSION; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; CYTOKINESIS; DOWN REGULATION; GENE; GENE FUNCTION; GENE OVEREXPRESSION; GENE REPRESSION; GENE SILENCING; HEPATOCELLULAR CARCINOMA CELL LINE; HUMAN; HUMAN CELL; KIF14 GENE; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UBIQUITINATION; UPREGULATION; GENETICS; HEPG2 CELL LINE; LIVER TUMOR; METABOLISM;

CARCINOMA, HEPATOCELLULAR; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLINS; CYTOKINESIS; GENE SILENCING; HEP G2 CELLS; HUMANS; KINESIN; LIVER NEOPLASMS; ONCOGENE PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; RNA, MESSENGER; S-PHASE KINASE-ASSOCIATED PROTEINS; UBIQUITINATION;

EID: 84902159925     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2014.23     Document Type: Article

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