Crystal structures of the archaeal UDP-GlcNAc 2-epimerase from Methanocaldococcus jannaschii reveal a conformational change induced by UDP-GlcNAc

Proteins: Structure, Function and Bioinformatics

Volumn 82, Issue 7, 2014, Pages 1519-1526

  Chen, Sheng Chia ^a,b   Huang, Chi Hung ^a,b,c   Shin Yang, Chia ^a,b   Liu, Jai Shin ^a   Kuan, Shu Min ^a   Chen, Yeh ^a  

^a HUNGKUANG UNIVERSITY   (Taiwan)

^b Taiwan Advance Biopharm (TABP) Inc   (Taiwan)

^c NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

Allosteric; Epimerization; Evolution; Rossmann fold; UDP ManNAc

Indexed keywords

URIDINE DIPHOSPHATE N ACETYLGLUCOSAMINE 2 EPIMERASE; ARCHAEAL PROTEIN; EPIMERASE; UDP ACETYLGLUCOSAMINE-2-EPIMERASE; URIDINE DIPHOSPHATE N ACETYLGLUCOSAMINE;

ARTICLE; BINDING SITE; BIOSYNTHESIS; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME STRUCTURE; LIGAND BINDING; METHANOCALDOCOCCUS JANNASCHII; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; ISOMERISM; METABOLISM; METHANOCALDOCOCCUS; MOLECULAR GENETICS; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; X RAY CRYSTALLOGRAPHY;

ARCHAEA; BACILLUS SUBTILIS; BACTERIA (MICROORGANISMS); METHANOCALDOCOCCUS JANNASCHII;

AMINO ACID SEQUENCE; ARCHAEAL PROTEINS; CARBOHYDRATE EPIMERASES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ISOMERISM; METHANOCALDOCOCCUS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; URIDINE DIPHOSPHATE N-ACETYLGLUCOSAMINE;

EID: 84902152041     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.24516     Document Type: Article

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