C-terminal β-strand swapping in a consensus-derived fibronectin Type III scaffold

Proteins: Structure, Function and Bioinformatics

Volumn 82, Issue 7, 2014, Pages 1359-1369

  Teplyakov, Alexey ^a   Obmolova, Galina ^a   Malia, Thomas J ^a   Luo, Jinquan ^a   Jacobs, Steven A ^a   Chan, Winnie ^a   Domingo, Derrick ^a   Baker, Audrey ^a   O'Neil, Karyn T ^a   Gilliland, Gary L ^a  

^a JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

Author keywords

3D domain swapping; Alternative scaffold; Fibronectin Type III domain; Tencon; X ray structure; strand swapping

Indexed keywords

DIMER; FIBRONECTIN; FIBRONECTIN TYPE III; HISTIDINE; METHIONINE; MONOMER; OLIGOMER; PHENYLALANINE; PROLINE; TENCON DIMER; UNCLASSIFIED DRUG; HYBRID PROTEIN; PROTEIN SUBUNIT;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ANTIGEN BINDING; ARTICLE; BETA SHEET; BETA STRAND SWAPPING; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; DIMERIZATION; GEL PERMEATION CHROMATOGRAPHY; HYDROGEN BOND; LIGHT SCATTERING; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN DOMAIN; STATIC LIGHT SCATTERING; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; PROTEIN SUBUNIT; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; CRYSTALLOGRAPHY, X-RAY; FIBRONECTINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT;

EID: 84902146722     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.24502     Document Type: Article

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