메뉴 건너뛰기




Volumn 9, Issue 10, 2014, Pages 1079-1088

Attenuated inhibition of medium spiny neurons participates in the pathogenesis of childhood depression

Author keywords

Brain injury; Childhood depression; Dopamine D2 like receptors; Excitatory inhibition; MSNs; Nerve regeneration; Neural plasticity; Neural regeneration; Neurophysiology; Nomifensine; NSFC grant; Nucleus accumbens; Wistar kyoto rats

Indexed keywords

DOPAMINE 2 RECEPTOR; NOMIFENSINE;

EID: 84902118055     PISSN: 16735374     EISSN: 18767958     Source Type: Journal    
DOI: 10.4103/1673-5374.133171     Document Type: Article
Times cited : (5)

References (67)
  • 1
    • 61449197838 scopus 로고    scopus 로고
    • Neurobiological mechanisms in major depressive disorder
    • Aan het Rot M, Mathew SJ, Charney DS (2009) Neurobiological mechanisms in major depressive disorder. CMAJ 180:305-313.
    • (2009) CMAJ , vol.180 , pp. 305-313
    • Aan het Rot, M.1    Mathew, S.J.2    Charney, D.S.3
  • 3
    • 33846092063 scopus 로고    scopus 로고
    • Childhood and adolescent depression
    • Bhatia SK, Bhatia SC (2007) Childhood and adolescent depression. Am Fam Physician 75:73-80.
    • (2007) Am Fam Physician , vol.75 , pp. 73-80
    • Bhatia, S.K.1    Bhatia, S.C.2
  • 4
    • 0345967827 scopus 로고    scopus 로고
    • Methylphenidate treatment during pre-and periadolescence alters behavioral responses to emotional stimuli at adulthood
    • Bolanos CA, Barrot M, Berton O, Wallace-Black D, Nestler EJ (2003) Methylphenidate treatment during pre-and periadolescence alters behavioral responses to emotional stimuli at adulthood. Biol Psychiatry 54:1317-1329.
    • (2003) Biol Psychiatry , vol.54 , pp. 1317-1329
    • Bolanos, C.A.1    Barrot, M.2    Berton, O.3    Wallace-Black, D.4    Nestler, E.J.5
  • 8
    • 77949285733 scopus 로고    scopus 로고
    • Synaptic plasticity in the mesolimbic system: Therapeutic implications for substance abuse
    • Chen BT, Hopf FW, Bonci A (2010) Synaptic plasticity in the mesolimbic system: therapeutic implications for substance abuse. Ann N Y Acad Sci 1187:129-139.
    • (2010) Ann N Y Acad Sci , vol.1187 , pp. 129-139
    • Chen, B.T.1    Hopf, F.W.2    Bonci, A.3
  • 9
    • 77955471134 scopus 로고    scopus 로고
    • Cabergoline, a dopamine receptor agonist, has an antidepressant-like property and enhances brain-derived neurotrophic factor signaling
    • Chiba S, Numakawa T, Ninomiya M, Yoon HS, Kunugi H (2010) Cabergoline, a dopamine receptor agonist, has an antidepressant-like property and enhances brain-derived neurotrophic factor signaling. Psychopharmacology 211:291-301.
    • (2010) Psychopharmacology , vol.211 , pp. 291-301
    • Chiba, S.1    Numakawa, T.2    Ninomiya, M.3    Yoon, H.S.4    Kunugi, H.5
  • 10
    • 74549191348 scopus 로고    scopus 로고
    • Dopamine is involved in the antidepressant-like effect of allopregnanolone in the forced swimming test in female rats
    • D'Aquila PS, Canu S, Sardella M, Spanu C, Serra G, Franconi F (2010) Dopamine is involved in the antidepressant-like effect of allopregnanolone in the forced swimming test in female rats. Behav Pharmacol 21:21-28.
    • (2010) Behav Pharmacol , vol.21 , pp. 21-28
    • D'Aquila, P.S.1    Canu, S.2    Sardella, M.3    Spanu, C.4    Serra, G.5    Franconi, F.6
  • 11
    • 0028180584 scopus 로고
    • Dopamine D2 receptors in depression measured with single photon emission computed tomography
    • D'Haenen HA, Bossuyt A (1994) Dopamine D2 receptors in depression measured with single photon emission computed tomography. Biol Psychiatry 35:128-132.
    • (1994) Biol Psychiatry , vol.35 , pp. 128-132
    • D'Haenen, H.A.1    Bossuyt, A.2
  • 12
    • 4444304974 scopus 로고    scopus 로고
    • A distinct neurochemical profile in WKY rats at baseline and in response to acute stress: Implications for animal models of anxiety and depression
    • De La Garza R, 2nd, Mahoney JJ, 3rd (2004) A distinct neurochemical profile in WKY rats at baseline and in response to acute stress: implications for animal models of anxiety and depression. Brain Res 1021: 209-218.
    • (2004) Brain Res , vol.1021 , pp. 209-218
    • de la Garza II, R.1    Mahoney III, J.J.2
  • 13
    • 0036241671 scopus 로고    scopus 로고
    • Effect of repeated treatment with tianeptine and fluoxetine on central dopamine D(2)/D(3) receptors
    • Dziedzicka-Wasylewska M, Rogoz Z, Skuza G, Dlaboga D, Maj J (2002) Effect of repeated treatment with tianeptine and fluoxetine on central dopamine D(2)/D(3) receptors. Behav Pharmacol 13:127-138.
    • (2002) Behav Pharmacol , vol.13 , pp. 127-138
    • Dziedzicka-Wasylewska, M.1    Rogoz, Z.2    Skuza, G.3    Dlaboga, D.4    Maj, J.5
  • 14
    • 83055188382 scopus 로고    scopus 로고
    • Chronic juvenile stress produces corticolimbic dendritic architectural remodeling and modulates emotional behavior in male and female rats
    • Eiland L, Ramroop J, Hill MN, Manley J, McEwen BS (2012) Chronic juvenile stress produces corticolimbic dendritic architectural remodeling and modulates emotional behavior in male and female rats. Psychoneuroendocrinology 37:39-47.
    • (2012) Psychoneuroendocrinology , vol.37 , pp. 39-47
    • Eiland, L.1    Ramroop, J.2    Hill, M.N.3    Manley, J.4    McEwen, B.S.5
  • 16
    • 84866940530 scopus 로고    scopus 로고
    • Dysfunctional hippocampal activity affects emotion and cognition in mood disorders
    • Femenia T, Gomez-Galan M, Lindskog M, Magara S (2012) Dysfunctional hippocampal activity affects emotion and cognition in mood disorders. Brain Res 1476:58-70.
    • (2012) Brain Res , vol.1476 , pp. 58-70
    • Femenia, T.1    Gomez-Galan, M.2    Lindskog, M.3    Magara, S.4
  • 17
    • 33846050620 scopus 로고    scopus 로고
    • Dopamine D2-like receptors and the antidepressant response
    • Gershon AA, Vishne T, Grunhaus L (2007) Dopamine D2-like receptors and the antidepressant response. Biol Psychiatry 61:145-153.
    • (2007) Biol Psychiatry , vol.61 , pp. 145-153
    • Gershon, A.A.1    Vishne, T.2    Grunhaus, L.3
  • 18
    • 77956063488 scopus 로고    scopus 로고
    • Alcohol-induced depressive-like behavior is associated with cortical norepinephrine reduction
    • Getachew B, Hauser SR, Taylor RE, Tizabi Y (2010) Alcohol-induced depressive-like behavior is associated with cortical norepinephrine reduction. Pharmacol Biochem Behav 96:395-401.
    • (2010) Pharmacol Biochem Behav , vol.96 , pp. 395-401
    • Getachew, B.1    Hauser, S.R.2    Taylor, R.E.3    Tizabi, Y.4
  • 19
    • 0032854619 scopus 로고    scopus 로고
    • Behavioral effects of acute and chronic fluoxetine in Wistar-Kyoto rats
    • Griebel G, Cohen C, Perrault G, Sanger DJ (1999) Behavioral effects of acute and chronic fluoxetine in Wistar-Kyoto rats. Physiol Behav 67:315-320.
    • (1999) Physiol Behav , vol.67 , pp. 315-320
    • Griebel, G.1    Cohen, C.2    Perrault, G.3    Sanger, D.J.4
  • 20
    • 82955241407 scopus 로고    scopus 로고
    • Effects of antidepressant drug treatment and psychotherapy on striatal and thalamic dopamine D2/3 receptors in major depressive disorder studied with [11C] raclopride PET
    • Hirvonen J, Hietala J, Kajander J, Markkula J, Rasi-Hakala H, Salminen JK, Nagren K, Aalto S, Karlsson H (2011) Effects of antidepressant drug treatment and psychotherapy on striatal and thalamic dopamine D2/3 receptors in major depressive disorder studied with [11C] raclopride PET. J Psychopharmacol 25:1329-1336.
    • (2011) J Psychopharmacol , vol.25 , pp. 1329-1336
    • Hirvonen, J.1    Hietala, J.2    Kajander, J.3    Markkula, J.4    Rasi-Hakala, H.5    Salminen, J.K.6    Nagren, K.7    Aalto, S.8    Karlsson, H.9
  • 22
    • 59949083264 scopus 로고    scopus 로고
    • Desipramine modulation of alpha-, gamma-synuclein, and the norepinephrine transporter in an animal model of depression
    • Jeannotte AM, McCarthy JG, Redei EE, Sidhu A (2009) Desipramine modulation of alpha-, gamma-synuclein, and the norepinephrine transporter in an animal model of depression. Neuropsychopharmacology 34:987-998.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 987-998
    • Jeannotte, A.M.1    McCarthy, J.G.2    Redei, E.E.3    Sidhu, A.4
  • 24
    • 0035199891 scopus 로고    scopus 로고
    • Drug addiction, dysregulation of reward, and allostasis
    • Koob GF, Le Moal M (2001) Drug addiction, dysregulation of reward, and allostasis. Neuropsychopharmacology 24:97-129.
    • (2001) Neuropsychopharmacology , vol.24 , pp. 97-129
    • Koob, G.F.1    Le Moal, M.2
  • 25
    • 67651017881 scopus 로고    scopus 로고
    • Physiology and pharmacology of striatal neurons
    • Kreitzer AC (2009) Physiology and pharmacology of striatal neurons. Annu Rev Neurosci 32:127-147.
    • (2009) Annu Rev Neurosci , vol.32 , pp. 127-147
    • Kreitzer, A.C.1
  • 26
    • 54049133277 scopus 로고    scopus 로고
    • The molecular neurobiology of depression
    • Krishnan V, Nestler EJ (2008) The molecular neurobiology of depression. Nature 455:894-902.
    • (2008) Nature , vol.455 , pp. 894-902
    • Krishnan, V.1    Nestler, E.J.2
  • 27
    • 0030697405 scopus 로고    scopus 로고
    • Are Wistar-Kyoto rats a genetic animal model of depression resistant to antidepressants?
    • Lahmame A, del Arco C, Pazos A, Yritia M, Armario A (1997) Are Wistar-Kyoto rats a genetic animal model of depression resistant to antidepressants? Eur J Pharmacol 337:115-123.
    • (1997) Eur J Pharmacol , vol.337 , pp. 115-123
    • Lahmame, A.1    del Arco, C.2    Pazos, A.3    Yritia, M.4    Armario, A.5
  • 28
    • 84887114618 scopus 로고    scopus 로고
    • Reward and aversion in a heterogeneous midbrain dopamine system
    • Lammel S, Lim BK, Malenka RC (2013) Reward and aversion in a heterogeneous midbrain dopamine system. Neuropharmacology. 76 Pt B:351-359.
    • (2013) Neuropharmacology , vol.76 , Issue.PART B , pp. 351-359
    • Lammel, S.1    Lim, B.K.2    Malenka, R.C.3
  • 29
    • 0033924369 scopus 로고    scopus 로고
    • Selective increase of dopamine D3 receptor gene expression as a common effect of chronic antidepressant treatments
    • Lammers CH, Diaz J, Schwartz JC, Sokoloff P (2000) Selective increase of dopamine D3 receptor gene expression as a common effect of chronic antidepressant treatments. Mol Psychiatry 5:378-388.
    • (2000) Mol Psychiatry , vol.5 , pp. 378-388
    • Lammers, C.H.1    Diaz, J.2    Schwartz, J.C.3    Sokoloff, P.4
  • 30
    • 77953808639 scopus 로고    scopus 로고
    • N-methyl-d-aspartic acid receptors are altered by stress and alcohol in Wistar-Kyoto rat brain
    • Lei Y, Tejani-Butt SM (2010) N-methyl-d-aspartic acid receptors are altered by stress and alcohol in Wistar-Kyoto rat brain. Neuroscience 169:125-131.
    • (2010) Neuroscience , vol.169 , pp. 125-131
    • Lei, Y.1    Tejani-Butt, S.M.2
  • 31
    • 79951512185 scopus 로고    scopus 로고
    • Stress-hyperresponsive WKY rats demonstrate depressed dorsal raphe neuronal excitability and dysregulated CRF-mediated responses
    • Lemos JC, Zhang G, Walsh T, Kirby LG, Akanwa A, Brooks-Kayal A, Beck SG (2011) Stress-hyperresponsive WKY rats demonstrate depressed dorsal raphe neuronal excitability and dysregulated CRF-mediated responses. Neuropsychopharmacology 36:721-734.
    • (2011) Neuropsychopharmacology , vol.36 , pp. 721-734
    • Lemos, J.C.1    Zhang, G.2    Walsh, T.3    Kirby, L.G.4    Akanwa, A.5    Brooks-Kayal, A.6    Beck, S.G.7
  • 32
    • 0034141630 scopus 로고    scopus 로고
    • Strain differences in the behavioral effects of antidepressant drugs in the rat forced swimming test
    • Lopez-Rubalcava C, Lucki I (2000) Strain differences in the behavioral effects of antidepressant drugs in the rat forced swimming test. Neuropsychopharmacology 22:191-199.
    • (2000) Neuropsychopharmacology , vol.22 , pp. 191-199
    • Lopez-Rubalcava, C.1    Lucki, I.2
  • 33
    • 67349112146 scopus 로고    scopus 로고
    • Two different putative genetic animal models of childhood depression--a review
    • Malkesman O, Weller A (2009) Two different putative genetic animal models of childhood depression--a review. Prog Neurobiol 88:153-169.
    • (2009) Prog Neurobiol , vol.88 , pp. 153-169
    • Malkesman, O.1    Weller, A.2
  • 34
    • 33847291454 scopus 로고    scopus 로고
    • Assessment of antidepressant and anxiolytic properties of NK1 antagonists and substance P in Wistar Kyoto rats
    • Malkesman O, Braw Y, Weller A (2007) Assessment of antidepressant and anxiolytic properties of NK1 antagonists and substance P in Wistar Kyoto rats. Physiol Behav 90:619-625.
    • (2007) Physiol Behav , vol.90 , pp. 619-625
    • Malkesman, O.1    Braw, Y.2    Weller, A.3
  • 38
    • 78650549350 scopus 로고    scopus 로고
    • Striatal structure and function in mood disorders: A comprehensive review
    • Marchand WR, Yurgelun-Todd D (2010) Striatal structure and function in mood disorders: a comprehensive review. Bipolar disord 12:764-785.
    • (2010) Bipolar Disord , vol.12 , pp. 764-785
    • Marchand, W.R.1    Yurgelun-Todd, D.2
  • 39
    • 0035682775 scopus 로고    scopus 로고
    • Neurogranin null mutant mice display performance deficits on spatial learning tasks with anxiety related components
    • Miyakawa T, Yared E, Pak JH, Huang FL, Huang KP, Crawley JN (2001) Neurogranin null mutant mice display performance deficits on spatial learning tasks with anxiety related components. Hippocampus 11:763-775.
    • (2001) Hippocampus , vol.11 , pp. 763-775
    • Miyakawa, T.1    Yared, E.2    Pak, J.H.3    Huang, F.L.4    Huang, K.P.5    Crawley, J.N.6
  • 40
    • 84868134394 scopus 로고    scopus 로고
    • Hypothesis with abnormal amino acid metabolism in depression and stress vulnerability in Wistar Kyoto rats
    • Nagasawa M, Ogino Y, Kurata K, Otsuka T, Yoshida J, Tomonaga S, Furuse M (2012) Hypothesis with abnormal amino acid metabolism in depression and stress vulnerability in Wistar Kyoto rats. Amino acids 43:2101-2111.
    • (2012) Amino Acids , vol.43 , pp. 2101-2111
    • Nagasawa, M.1    Ogino, Y.2    Kurata, K.3    Otsuka, T.4    Yoshida, J.5    Tomonaga, S.6    Furuse, M.7
  • 41
    • 33746900423 scopus 로고    scopus 로고
    • The mesolimbic dopamine reward circuit in depression
    • Nestler EJ, Carlezon WA, Jr. (2006) The mesolimbic dopamine reward circuit in depression. Biol Psychiatry 59:1151-1159.
    • (2006) Biol Psychiatry , vol.59 , pp. 1151-1159
    • Nestler, E.J.1    Carlezon Jr., W.A.2
  • 42
    • 1342301451 scopus 로고    scopus 로고
    • Dopamine: A key regulator to adapt action, emotion, motivation and cognition
    • Nieoullon A, Coquerel A (2003) Dopamine: a key regulator to adapt action, emotion, motivation and cognition. Curr Opin Neurol 16 Suppl 2:S3-9.
    • (2003) Curr Opin Neurol 16 Suppl , vol.2
    • Nieoullon, A.1    Coquerel, A.2
  • 43
    • 0027481024 scopus 로고
    • Physiological and morphological properties of accumbens core and shell neurons recorded in vitro
    • O'Donnell P, Grace AA (1993) Physiological and morphological properties of accumbens core and shell neurons recorded in vitro. Synapse 13:135-160.
    • (1993) Synapse , vol.13 , pp. 135-160
    • O'Donnell, P.1    Grace, A.A.2
  • 44
    • 77955768871 scopus 로고    scopus 로고
    • Comparison of hippocampal metabotropic glutamate receptor 7 (mGlu7) mRNA levels in two animal models of depression
    • O'Mahony CM, Bravo JA, Dinan TG, Cryan JF (2010) Comparison of hippocampal metabotropic glutamate receptor 7 (mGlu7) mRNA levels in two animal models of depression. Neurosci Lett 482:137-141.
    • (2010) Neurosci Lett , vol.482 , pp. 137-141
    • O'Mahony, C.M.1    Bravo, J.A.2    Dinan, T.G.3    Cryan, J.F.4
  • 45
    • 78650122744 scopus 로고    scopus 로고
    • Strain differences in the neurochemical response to chronic restraint stress in the rat: Relevance to depression
    • O'Mahony CM, Clarke G, Gibney S, Dinan TG, Cryan JF (2011) Strain differences in the neurochemical response to chronic restraint stress in the rat: relevance to depression. Pharmacol Biochem Behav 97:690-699.
    • (2011) Pharmacol Biochem Behav , vol.97 , pp. 690-699
    • O'Mahony, C.M.1    Clarke, G.2    Gibney, S.3    Dinan, T.G.4    Cryan, J.F.5
  • 46
    • 84856351442 scopus 로고    scopus 로고
    • Modeling depression in animal models
    • Overstreet DH (2012) Modeling depression in animal models. Methods Mol Biol 829:125-144.
    • (2012) Methods Mol Biol , vol.829 , pp. 125-144
    • Overstreet, D.H.1
  • 48
    • 0021867618 scopus 로고
    • Bregma, lambda and the interaural midpoint in stereotaxic surgery with rats of different sex, strain and weight
    • Paxinos G, Watson C, Pennisi M, Topple A (1985) Bregma, lambda and the interaural midpoint in stereotaxic surgery with rats of different sex, strain and weight. J Neurosci Methods 13:139-143.
    • (1985) J Neurosci Methods , vol.13 , pp. 139-143
    • Paxinos, G.1    Watson, C.2    Pennisi, M.3    Topple, A.4
  • 49
    • 0018196837 scopus 로고
    • "Behavioural despair" in rats and mice: Strain differences and the effects of imipramine
    • Porsolt RD, Bertin A, Jalfre M (1978) "Behavioural despair" in rats and mice: strain differences and the effects of imipramine. Eur J Pharmacology 51:291-294.
    • (1978) Eur J Pharmacology , vol.51 , pp. 291-294
    • Porsolt, R.D.1    Bertin, A.2    Jalfre, M.3
  • 53
    • 84862181146 scopus 로고    scopus 로고
    • Behavioral effects of environmental enrichment during gestation in WKY and Wistar rats
    • Rosenfeld A, Weller A (2012) Behavioral effects of environmental enrichment during gestation in WKY and Wistar rats. Behav Brain Res 233:245-255.
    • (2012) Behav Brain Res , vol.233 , pp. 245-255
    • Rosenfeld, A.1    Weller, A.2
  • 55
    • 77956619988 scopus 로고    scopus 로고
    • Central monoamine levels differ between rat strains used in studies of depressive behavior
    • Scholl JL, Renner KJ, Forster GL, Tejani-Butt S (2010) Central monoamine levels differ between rat strains used in studies of depressive behavior. Brain Res 1355:41-51.
    • (2010) Brain Res , vol.1355 , pp. 41-51
    • Scholl, J.L.1    Renner, K.J.2    Forster, G.L.3    Tejani-Butt, S.4
  • 56
    • 79955647585 scopus 로고    scopus 로고
    • Effects of early life trauma are dependent on genetic predisposition: A rat study
    • Sterley TL, Howells FM, Russell VA (2011) Effects of early life trauma are dependent on genetic predisposition: a rat study. Behav Brain Funct 7:11.
    • (2011) Behav Brain Funct , vol.7 , pp. 11
    • Sterley, T.L.1    Howells, F.M.2    Russell, V.A.3
  • 59
    • 80555131126 scopus 로고    scopus 로고
    • Stress responses and the mesolimbic dopamine system: Social contexts and sex differences
    • Trainor BC (2011) Stress responses and the mesolimbic dopamine system: social contexts and sex differences. Horm Behav 60:457-469.
    • (2011) Horm Behav , vol.60 , pp. 457-469
    • Trainor, B.C.1
  • 60
    • 84865861902 scopus 로고    scopus 로고
    • DRD3, but not BDNF, genotype affects treatment response to paroxetine in major depressive disorder: A preliminary study
    • Tsuchimine S, Yasui-Furukori N, Nakagami T, Sato Y, Kaneko S (2012) DRD3, but not BDNF, genotype affects treatment response to paroxetine in major depressive disorder: a preliminary study. J Clin Psychopharmacol 32:724-726.
    • (2012) J Clin Psychopharmacol , vol.32 , pp. 724-726
    • Tsuchimine, S.1    Yasui-Furukori, N.2    Nakagami, T.3    Sato, Y.4    Kaneko, S.5
  • 61
    • 84861007179 scopus 로고    scopus 로고
    • Dysfunction in fatty acid amide hydrolase is associated with depressive-like behavior in Wistar Kyoto rats
    • Vinod KY, Xie S, Psychoyos D, Hungund BL, Cooper TB, Tejani-Butt SM (2012) Dysfunction in fatty acid amide hydrolase is associated with depressive-like behavior in Wistar Kyoto rats. PloS One 7:e36743.
    • (2012) PloS One , vol.7
    • Vinod, K.Y.1    Xie, S.2    Psychoyos, D.3    Hungund, B.L.4    Cooper, T.B.5    Tejani-Butt, S.M.6
  • 63
    • 84858168885 scopus 로고    scopus 로고
    • Effects of electroacupuncture on depression in a rat model
    • Xu S, Li S, Shen X, Meng X, Lao L (2011) Effects of electroacupuncture on depression in a rat model. Acupunct Electrother Res 36:259-273.
    • (2011) Acupunct Electrother Res , vol.36 , pp. 259-273
    • Xu, S.1    Li, S.2    Shen, X.3    Meng, X.4    Lao, L.5
  • 64
    • 77951662519 scopus 로고    scopus 로고
    • Mother-child conflict and its moderating effects on depression outcomes in a preventive intervention for adolescent depression
    • Young JF, Gallop R, Mufson L (2009) Mother-child conflict and its moderating effects on depression outcomes in a preventive intervention for adolescent depression. J Clin Child Adolesc Psychol 38:696-704.
    • (2009) J Clin Child Adolesc Psychol , vol.38 , pp. 696-704
    • Young, J.F.1    Gallop, R.2    Mufson, L.3
  • 65
    • 78649907652 scopus 로고    scopus 로고
    • The role of mesocorticolimbic dopamine in regulating interactions between drugs of abuse and social behavior
    • Young KA, Gobrogge KL, Wang Z (2011) The role of mesocorticolimbic dopamine in regulating interactions between drugs of abuse and social behavior. Neurosci Biobehav Rev 35:498-515.
    • (2011) Neurosci Biobehav Rev , vol.35 , pp. 498-515
    • Young, K.A.1    Gobrogge, K.L.2    Wang, Z.3
  • 66
    • 85047697355 scopus 로고    scopus 로고
    • Association of a triallelic serotonin transporter gene promoter region (5-HTTLPR) polymorphism with stressful life events and severity of depression
    • Zalsman G, Huang YY, Oquendo MA, Burke AK, Hu XZ, Brent DA, Ellis SP, Goldman D, Mann JJ (2006) Association of a triallelic serotonin transporter gene promoter region (5-HTTLPR) polymorphism with stressful life events and severity of depression. Am J Psychiatry 163:1588-1593.
    • (2006) Am J Psychiatry , vol.163 , pp. 1588-1593
    • Zalsman, G.1    Huang, Y.Y.2    Oquendo, M.A.3    Burke, A.K.4    Hu, X.Z.5    Brent, D.A.6    Ellis, S.P.7    Goldman, D.8    Mann, J.J.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.