메뉴 건너뛰기




Volumn 275, Issue 6, 2014, Pages 640-651

The HLA locus contains novel foetal susceptibility alleles for congenital heart block with significant paternal influence

Author keywords

04; Autoantibodies; Congenital heart block; HLA DRB1; MHC; Neonatal lupus erythematosus

Indexed keywords

HLA DRB1 ANTIGEN; RO ANTIBODY;

EID: 84902075625     PISSN: 09546820     EISSN: 13652796     Source Type: Journal    
DOI: 10.1111/joim.12179     Document Type: Article
Times cited : (26)

References (63)
  • 1
    • 84856503820 scopus 로고    scopus 로고
    • Pregnancy outcomes in patients with systemic autoimmunity
    • Canti V, Castiglioni MT, Rosa S et al. Pregnancy outcomes in patients with systemic autoimmunity. Autoimmunity 2012; 45: 169-175.
    • (2012) Autoimmunity , vol.45 , pp. 169-175
    • Canti, V.1    Castiglioni, M.T.2    Rosa, S.3
  • 3
    • 77955284867 scopus 로고    scopus 로고
    • Autoantibodies associated with congenital heart block
    • Salomonsson S, Strandberg L. Autoantibodies associated with congenital heart block. Scand J Immunol 2010; 72: 185-188.
    • (2010) Scand J Immunol , vol.72 , pp. 185-188
    • Salomonsson, S.1    Strandberg, L.2
  • 4
    • 0028265118 scopus 로고
    • Autoantibody-associated congenital heart block: outcome in mothers and children
    • Waltuck J, Buyon JP. Autoantibody-associated congenital heart block: outcome in mothers and children. Ann Intern Med 1994; 120: 544-551.
    • (1994) Ann Intern Med , vol.120 , pp. 544-551
    • Waltuck, J.1    Buyon, J.P.2
  • 5
    • 0029990184 scopus 로고    scopus 로고
    • Long-term outcome of mothers of children with complete congenital heart block
    • Press J, Uziel Y, Laxer RM, Luy L, Hamilton RM, Silverman ED. Long-term outcome of mothers of children with complete congenital heart block. Am J Med 1996; 100: 328-332.
    • (1996) Am J Med , vol.100 , pp. 328-332
    • Press, J.1    Uziel, Y.2    Laxer, R.M.3    Luy, L.4    Hamilton, R.M.5    Silverman, E.D.6
  • 6
    • 0034745328 scopus 로고    scopus 로고
    • The rate of recurrence of isolated congenital heart block: a population-based study
    • Julkunen H, Eronen M. The rate of recurrence of isolated congenital heart block: a population-based study. Arthritis Rheum 2001; 44: 487-488.
    • (2001) Arthritis Rheum , vol.44 , pp. 487-488
    • Julkunen, H.1    Eronen, M.2
  • 7
    • 0021940551 scopus 로고
    • Maternal connective tissue disease and congenital heart block. Demonstration of immunoglobulin in cardiac tissue
    • Litsey SE, Noonan JA, O'Connor WN, Cottrill CM, Mitchell B. Maternal connective tissue disease and congenital heart block. Demonstration of immunoglobulin in cardiac tissue. N Engl J Med 1985; 312: 98-100.
    • (1985) N Engl J Med , vol.312 , pp. 98-100
    • Litsey, S.E.1    Noonan, J.A.2    O'Connor, W.N.3    Cottrill, C.M.4    Mitchell, B.5
  • 8
    • 19944430671 scopus 로고    scopus 로고
    • Ro/SSA autoantibodies directly bind cardiomyocytes, disturb calcium homeostasis, and mediate congenital heart block
    • Salomonsson S, Sonesson SE, Ottosson L et al. Ro/SSA autoantibodies directly bind cardiomyocytes, disturb calcium homeostasis, and mediate congenital heart block. J Exp Med 2005; 201: 11-17.
    • (2005) J Exp Med , vol.201 , pp. 11-17
    • Salomonsson, S.1    Sonesson, S.E.2    Ottosson, L.3
  • 9
    • 0029071457 scopus 로고
    • Autoantibody response to the Ro/La particle may predict outcome in neonatal lupus erythematosus
    • Silverman ED, Buyon J, Laxer RM et al. Autoantibody response to the Ro/La particle may predict outcome in neonatal lupus erythematosus. Clin Exp Immunol 1995; 100: 499-505.
    • (1995) Clin Exp Immunol , vol.100 , pp. 499-505
    • Silverman, E.D.1    Buyon, J.2    Laxer, R.M.3
  • 10
    • 0024410973 scopus 로고
    • Acquired congenital heart block. Pattern of maternal antibody response to biochemically defined antigens of the SSA/Ro-SSB/La system in neonatal lupus
    • Buyon JP, Ben-Chetrit E, Karp S et al. Acquired congenital heart block. Pattern of maternal antibody response to biochemically defined antigens of the SSA/Ro-SSB/La system in neonatal lupus. J Clin Invest 1989; 84: 627-634.
    • (1989) J Clin Invest , vol.84 , pp. 627-634
    • Buyon, J.P.1    Ben-Chetrit, E.2    Karp, S.3
  • 12
    • 51349128276 scopus 로고    scopus 로고
    • Antibodies to amino acid 200-239 (p200) of Ro52 as serological markers for the risk of developing congenital heart block
    • Strandberg L, Winqvist O, Sonesson SE et al. Antibodies to amino acid 200-239 (p200) of Ro52 as serological markers for the risk of developing congenital heart block. Clin Exp Immunol 2008; 154: 30-37.
    • (2008) Clin Exp Immunol , vol.154 , pp. 30-37
    • Strandberg, L.1    Winqvist, O.2    Sonesson, S.E.3
  • 13
    • 0028935959 scopus 로고
    • Isolated congenital complete heart block: longterm outcome of children and immunogenetic study
    • Brucato A, Gasparini M, Vignati G et al. Isolated congenital complete heart block: longterm outcome of children and immunogenetic study. J Rheumatol 1995; 22: 541-543.
    • (1995) J Rheumatol , vol.22 , pp. 541-543
    • Brucato, A.1    Gasparini, M.2    Vignati, G.3
  • 14
    • 0031745967 scopus 로고    scopus 로고
    • Autoimmune-associated congenital heart block: demographics, mortality, morbidity and recurrence rates obtained from a national neonatal lupus registry
    • Buyon JP, Hiebert R, Copel J et al. Autoimmune-associated congenital heart block: demographics, mortality, morbidity and recurrence rates obtained from a national neonatal lupus registry. J Am Coll Cardiol 1998; 31: 1658-1666.
    • (1998) J Am Coll Cardiol , vol.31 , pp. 1658-1666
    • Buyon, J.P.1    Hiebert, R.2    Copel, J.3
  • 15
    • 0042466310 scopus 로고    scopus 로고
    • Birth order, gender and recurrence rate in autoantibody-associated congenital heart block: implications for pathogenesis and family counseling
    • Solomon DG, Rupel A, Buyon JP. Birth order, gender and recurrence rate in autoantibody-associated congenital heart block: implications for pathogenesis and family counseling. Lupus 2003; 12: 646-647.
    • (2003) Lupus , vol.12 , pp. 646-647
    • Solomon, D.G.1    Rupel, A.2    Buyon, J.P.3
  • 16
    • 33745860410 scopus 로고    scopus 로고
    • Ro52, Ro60 and La IgG autoantibody levels and Ro52 IgG subclass profiles longitudinally throughout pregnancy in congenital heart block risk pregnancies
    • Strandberg L, Salomonsson S, Bremme K, Sonesson S, Wahren-Herlenius M. Ro52, Ro60 and La IgG autoantibody levels and Ro52 IgG subclass profiles longitudinally throughout pregnancy in congenital heart block risk pregnancies. Lupus 2006; 15: 346-353.
    • (2006) Lupus , vol.15 , pp. 346-353
    • Strandberg, L.1    Salomonsson, S.2    Bremme, K.3    Sonesson, S.4    Wahren-Herlenius, M.5
  • 17
    • 84857237951 scopus 로고    scopus 로고
    • Development of heart block in children of SSA/SSB-autoantibody-positive women is associated with maternal age and displays a season-of-birth pattern
    • Ambrosi A, Salomonsson S, Eliasson H et al. Development of heart block in children of SSA/SSB-autoantibody-positive women is associated with maternal age and displays a season-of-birth pattern. Ann Rheum Dis 2012; 71: 334-340.
    • (2012) Ann Rheum Dis , vol.71 , pp. 334-340
    • Ambrosi, A.1    Salomonsson, S.2    Eliasson, H.3
  • 18
    • 79953164590 scopus 로고    scopus 로고
    • Gene-environment interaction in induction of autoimmunity
    • Wahren-Herlenius M, Kuchroo VK. Gene-environment interaction in induction of autoimmunity. Semin Immunol 2011; 23: 65-66.
    • (2011) Semin Immunol , vol.23 , pp. 65-66
    • Wahren-Herlenius, M.1    Kuchroo, V.K.2
  • 19
    • 78649735055 scopus 로고    scopus 로고
    • Maternal MHC regulates generation of pathogenic antibodies and fetal MHC-encoded genes determine susceptibility in congenital heart block
    • Strandberg LS, Ambrosi A, Jagodic M et al. Maternal MHC regulates generation of pathogenic antibodies and fetal MHC-encoded genes determine susceptibility in congenital heart block. J Immunol 2010; 185: 3574-3582.
    • (2010) J Immunol , vol.185 , pp. 3574-3582
    • Strandberg, L.S.1    Ambrosi, A.2    Jagodic, M.3
  • 20
    • 80053540936 scopus 로고    scopus 로고
    • A population-based investigation of the autoantibody profile in mothers of children with atrioventricular block
    • Salomonsson S, Dzikaite V, Zeffer E et al. A population-based investigation of the autoantibody profile in mothers of children with atrioventricular block. Scand J Immunol 2011; 74: 511-517.
    • (2011) Scand J Immunol , vol.74 , pp. 511-517
    • Salomonsson, S.1    Dzikaite, V.2    Zeffer, E.3
  • 21
    • 84871019358 scopus 로고    scopus 로고
    • Neurodevelopment in children with and without congenital heart block born to anti-Ro/SSA-positive mothers
    • Skog A, Tingstrom J, Salomonsson S, Sonesson SE, Wahren-Herlenius M. Neurodevelopment in children with and without congenital heart block born to anti-Ro/SSA-positive mothers. Acta Paediatr 2013; 102: 40-46.
    • (2013) Acta Paediatr , vol.102 , pp. 40-46
    • Skog, A.1    Tingstrom, J.2    Salomonsson, S.3    Sonesson, S.E.4    Wahren-Herlenius, M.5
  • 22
    • 0020436689 scopus 로고
    • The 1982 revised criteria for the classification of systemic lupus erythematosus
    • Tan EM, Cohen AS, Fries JF et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982; 25: 1271-1277.
    • (1982) Arthritis Rheum , vol.25 , pp. 1271-1277
    • Tan, E.M.1    Cohen, A.S.2    Fries, J.F.3
  • 23
    • 0036092482 scopus 로고    scopus 로고
    • Classification criteria for Sjogren's syndrome: a revised version of the European criteria proposed by the American-European Consensus Group
    • Vitali C, Bombardieri S, Jonsson R et al. Classification criteria for Sjogren's syndrome: a revised version of the European criteria proposed by the American-European Consensus Group. Ann Rheum Dis 2002; 61: 554-558.
    • (2002) Ann Rheum Dis , vol.61 , pp. 554-558
    • Vitali, C.1    Bombardieri, S.2    Jonsson, R.3
  • 24
    • 0023945481 scopus 로고
    • The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
    • Arnett FC, Edworthy SM, Bloch DA et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988; 31: 315-324.
    • (1988) Arthritis Rheum , vol.31 , pp. 315-324
    • Arnett, F.C.1    Edworthy, S.M.2    Bloch, D.A.3
  • 25
    • 0041885145 scopus 로고    scopus 로고
    • Quantification of the influence of cigarette smoking on rheumatoid arthritis: results from a population based case-control study, using incident cases
    • Stolt P, Bengtsson C, Nordmark B et al. Quantification of the influence of cigarette smoking on rheumatoid arthritis: results from a population based case-control study, using incident cases. Ann Rheum Dis 2003; 62: 835-841.
    • (2003) Ann Rheum Dis , vol.62 , pp. 835-841
    • Stolt, P.1    Bengtsson, C.2    Nordmark, B.3
  • 26
    • 79953221100 scopus 로고    scopus 로고
    • A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease
    • Coronary Artery Disease (C4D) Genetics Consortium
    • Coronary Artery Disease (C4D) Genetics Consortium. A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease. Nat Genet 2011; 43: 339-44.
    • (2011) Nat Genet , vol.43 , pp. 339-344
  • 27
    • 34548849168 scopus 로고    scopus 로고
    • TRAF1-C5 as a risk locus for rheumatoid arthritis-a genomewide study
    • Plenge RM, Seielstad M, Padyukov L et al. TRAF1-C5 as a risk locus for rheumatoid arthritis-a genomewide study. N Engl J Med 2007; 357: 1199-1209.
    • (2007) N Engl J Med , vol.357 , pp. 1199-1209
    • Plenge, R.M.1    Seielstad, M.2    Padyukov, L.3
  • 28
    • 84959801619 scopus 로고
    • Statistical aspects of the analysis of data from retrospective studies of disease
    • Mantel N, Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 1959; 22: 719-748.
    • (1959) J Natl Cancer Inst , vol.22 , pp. 719-748
    • Mantel, N.1    Haenszel, W.2
  • 29
    • 41649094148 scopus 로고    scopus 로고
    • Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data
    • Dudbridge F. Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data. Hum Hered 2008; 66: 87-98.
    • (2008) Hum Hered , vol.66 , pp. 87-98
    • Dudbridge, F.1
  • 30
    • 9444295337 scopus 로고    scopus 로고
    • Gene map of the extended human MHC
    • Horton R, Wilming L, Rand V et al. Gene map of the extended human MHC. Nat Rev Genet 2004; 5: 889-899.
    • (2004) Nat Rev Genet , vol.5 , pp. 889-899
    • Horton, R.1    Wilming, L.2    Rand, V.3
  • 31
    • 77049310401 scopus 로고
    • The estimation and significance of the logarithm of a ratio of frequencies
    • Haldane JB. The estimation and significance of the logarithm of a ratio of frequencies. Ann Hum Genet 1956; 20: 309-311.
    • (1956) Ann Hum Genet , vol.20 , pp. 309-311
    • Haldane, J.B.1
  • 32
    • 0026691249 scopus 로고
    • HLA-DR typing by PCR amplification with sequence-specific primers (PCR-SSP) in 2 hours: an alternative to serological DR typing in clinical practice including donor-recipient matching in cadaveric transplantation
    • Olerup O, Zetterquist H. HLA-DR typing by PCR amplification with sequence-specific primers (PCR-SSP) in 2 hours: an alternative to serological DR typing in clinical practice including donor-recipient matching in cadaveric transplantation. Tissue Antigens 1992; 39: 225-235.
    • (1992) Tissue Antigens , vol.39 , pp. 225-235
    • Olerup, O.1    Zetterquist, H.2
  • 33
    • 79952138032 scopus 로고    scopus 로고
    • Smoking and two human leukocyte antigen genes interact to increase the risk for multiple sclerosis
    • Hedstrom AK, Sundqvist E, Baarnhielm M et al. Smoking and two human leukocyte antigen genes interact to increase the risk for multiple sclerosis. Brain 2011; 134: 653-664.
    • (2011) Brain , vol.134 , pp. 653-664
    • Hedstrom, A.K.1    Sundqvist, E.2    Baarnhielm, M.3
  • 34
    • 77956340532 scopus 로고    scopus 로고
    • Two HLA class I genes independently associated with multiple sclerosis
    • Link J, Lorentzen AR, Kockum I et al. Two HLA class I genes independently associated with multiple sclerosis. J Neuroimmunol 2010; 226: 172-176.
    • (2010) J Neuroimmunol , vol.226 , pp. 172-176
    • Link, J.1    Lorentzen, A.R.2    Kockum, I.3
  • 35
    • 84857237844 scopus 로고    scopus 로고
    • Anti-Ro52 monoclonal antibodies specific for amino acid 200-239, but not other Ro52 epitopes, induce congenital heart block in a rat model
    • Ambrosi A, Dzikaite V, Park J et al. Anti-Ro52 monoclonal antibodies specific for amino acid 200-239, but not other Ro52 epitopes, induce congenital heart block in a rat model. Ann Rheum Dis 2012; 71: 448-454.
    • (2012) Ann Rheum Dis , vol.71 , pp. 448-454
    • Ambrosi, A.1    Dzikaite, V.2    Park, J.3
  • 36
    • 0024453507 scopus 로고
    • The immunogenetic relationship between anti-Ro(SS-A)/La(SS-B) antibody positive Sjogren's/lupus erythematosus overlap syndrome and the neonatal lupus syndrome
    • Alexander EL, McNicholl J, Watson RM, Bias W, Reichlin M, Provost TT. The immunogenetic relationship between anti-Ro(SS-A)/La(SS-B) antibody positive Sjogren's/lupus erythematosus overlap syndrome and the neonatal lupus syndrome. J Invest Dermatol 1989; 93: 751-756.
    • (1989) J Invest Dermatol , vol.93 , pp. 751-756
    • Alexander, E.L.1    McNicholl, J.2    Watson, R.M.3    Bias, W.4    Reichlin, M.5    Provost, T.T.6
  • 37
    • 0031977447 scopus 로고    scopus 로고
    • Polymorphisms of HLA class II genes and autoimmune responses to Ro/SS-A-La/SS-B among Japanese subjects
    • Miyagawa S, Shinohara K, Nakajima M et al. Polymorphisms of HLA class II genes and autoimmune responses to Ro/SS-A-La/SS-B among Japanese subjects. Arthritis Rheum 1998; 41: 927-934.
    • (1998) Arthritis Rheum , vol.41 , pp. 927-934
    • Miyagawa, S.1    Shinohara, K.2    Nakajima, M.3
  • 38
    • 0030725167 scopus 로고    scopus 로고
    • Neonatal lupus erythematosus: studies on HLA class II genes and autoantibody profiles in Japanese mothers
    • Miyagawa S, Shinohara K, Kidoguchi K et al. Neonatal lupus erythematosus: studies on HLA class II genes and autoantibody profiles in Japanese mothers. Autoimmunity 1997; 26: 95-101.
    • (1997) Autoimmunity , vol.26 , pp. 95-101
    • Miyagawa, S.1    Shinohara, K.2    Kidoguchi, K.3
  • 39
    • 79954997147 scopus 로고    scopus 로고
    • Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase Btk
    • 416-U71
    • Liu XG, Zhan ZZ, Li D et al. Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase Btk. Nat Immunol 2011; 12: 416-U71.
    • (2011) Nat Immunol , vol.12
    • Liu, X.G.1    Zhan, Z.Z.2    Li, D.3
  • 40
    • 84860333371 scopus 로고    scopus 로고
    • Congenital heart block: evidence for a pathogenic role of maternal autoantibodies
    • Ambrosi A, Wahren-Herlenius M. Congenital heart block: evidence for a pathogenic role of maternal autoantibodies. Arthritis Res Ther 2012; 14: 208.
    • (2012) Arthritis Res Ther , vol.14 , pp. 208
    • Ambrosi, A.1    Wahren-Herlenius, M.2
  • 41
    • 10344227722 scopus 로고    scopus 로고
    • An update of the HLA genomic region, locus information and disease associations: 2004
    • Shiina T, Inoko H, Kulski JK. An update of the HLA genomic region, locus information and disease associations: 2004. Tissue Antigens 2004; 64: 631-649.
    • (2004) Tissue Antigens , vol.64 , pp. 631-649
    • Shiina, T.1    Inoko, H.2    Kulski, J.K.3
  • 42
    • 78249257797 scopus 로고    scopus 로고
    • Identification of candidate loci at 6p21 and 21q22 in a genome-wide association study of cardiac manifestations of neonatal lupus
    • Clancy RM, Marion MC, Kaufman KM et al. Identification of candidate loci at 6p21 and 21q22 in a genome-wide association study of cardiac manifestations of neonatal lupus. Arthritis Rheum 2010; 62: 3415-3424.
    • (2010) Arthritis Rheum , vol.62 , pp. 3415-3424
    • Clancy, R.M.1    Marion, M.C.2    Kaufman, K.M.3
  • 43
    • 0021752445 scopus 로고
    • Neonatal lupus erythematosus. A clinical, serological and immunogenetic study with review of the literature
    • Watson RM, Lane AT, Barnett NK, Bias WB, Arnett FC, Provost TT. Neonatal lupus erythematosus. A clinical, serological and immunogenetic study with review of the literature. Medicine (Baltimore) 1984; 63: 362-378.
    • (1984) Medicine (Baltimore) , vol.63 , pp. 362-378
    • Watson, R.M.1    Lane, A.T.2    Barnett, N.K.3    Bias, W.B.4    Arnett, F.C.5    Provost, T.T.6
  • 44
    • 0021039114 scopus 로고
    • Immunogenetics of the neonatal lupus syndrome
    • Lee LA, Bias WB, Arnett FC Jr et al. Immunogenetics of the neonatal lupus syndrome. Ann Intern Med 1983; 99: 592-596.
    • (1983) Ann Intern Med , vol.99 , pp. 592-596
    • Lee, L.A.1    Bias, W.B.2    Arnett Jr, F.C.3
  • 45
    • 0020692131 scopus 로고
    • Neonatal lupus erythematosus with heart block: family study of a patient with anti-SS-A and SS-B antibodies
    • Lockshin MD, Gibofsky A, Peebles CL, Gigli I, Fotino M, Hurwitz S. Neonatal lupus erythematosus with heart block: family study of a patient with anti-SS-A and SS-B antibodies. Arthritis Rheum 1983; 26: 210-213.
    • (1983) Arthritis Rheum , vol.26 , pp. 210-213
    • Lockshin, M.D.1    Gibofsky, A.2    Peebles, C.L.3    Gigli, I.4    Fotino, M.5    Hurwitz, S.6
  • 46
    • 23944482088 scopus 로고    scopus 로고
    • Neonatal lupus erythematosus: a review of the racial differences and similarities in clinical, serological and immunogenetic features of Japanese versus Caucasian patients
    • Miyagawa S. Neonatal lupus erythematosus: a review of the racial differences and similarities in clinical, serological and immunogenetic features of Japanese versus Caucasian patients. J Dermatol 2005; 32: 514-522.
    • (2005) J Dermatol , vol.32 , pp. 514-522
    • Miyagawa, S.1
  • 47
    • 0032969961 scopus 로고    scopus 로고
    • Role of HLA in congenital heart block: susceptibility alleles in children
    • Siren MK, Julkunen H, Kaaja R, Ekblad H, Koskimies S. Role of HLA in congenital heart block: susceptibility alleles in children. Lupus 1999; 8: 60-67.
    • (1999) Lupus , vol.8 , pp. 60-67
    • Siren, M.K.1    Julkunen, H.2    Kaaja, R.3    Ekblad, H.4    Koskimies, S.5
  • 48
    • 0345827517 scopus 로고    scopus 로고
    • Immunohistologic evidence supports apoptosis, IgG deposition, and novel macrophage/fibroblast crosstalk in the pathologic cascade leading to congenital heart block
    • Clancy RM, Kapur RP, Molad Y, Askanase AD, Buyon JP. Immunohistologic evidence supports apoptosis, IgG deposition, and novel macrophage/fibroblast crosstalk in the pathologic cascade leading to congenital heart block. Arthritis Rheum 2004; 50: 173-182.
    • (2004) Arthritis Rheum , vol.50 , pp. 173-182
    • Clancy, R.M.1    Kapur, R.P.2    Molad, Y.3    Askanase, A.D.4    Buyon, J.P.5
  • 49
    • 0033866604 scopus 로고    scopus 로고
    • The development of the immune system during pregnancy and early life
    • Holt PG, Jones CA. The development of the immune system during pregnancy and early life. Allergy 2000; 55: 688-697.
    • (2000) Allergy , vol.55 , pp. 688-697
    • Holt, P.G.1    Jones, C.A.2
  • 50
    • 80052251701 scopus 로고    scopus 로고
    • A novel role of endothelin-1 in linking Toll-like receptor 7-mediated inflammation to fibrosis in congenital heart block
    • Alvarez D, Briassouli P, Clancy RM et al. A novel role of endothelin-1 in linking Toll-like receptor 7-mediated inflammation to fibrosis in congenital heart block. J Biol Chem 2011; 286: 30444-30454.
    • (2011) J Biol Chem , vol.286 , pp. 30444-30454
    • Alvarez, D.1    Briassouli, P.2    Clancy, R.M.3
  • 51
    • 85007072561 scopus 로고    scopus 로고
    • Influence of season of birth and maternal age in the development of congenital heart block in Anti-Ro-SSA/La-SSB positive pregnancies
    • Ambrosi A, Salomonsson S, Eliasson H et al. Influence of season of birth and maternal age in the development of congenital heart block in Anti-Ro-SSA/La-SSB positive pregnancies. Scand J Immunol 2010; 72: 265.
    • (2010) Scand J Immunol , vol.72 , pp. 265
    • Ambrosi, A.1    Salomonsson, S.2    Eliasson, H.3
  • 52
    • 0025290553 scopus 로고
    • Association of chronic Lyme arthritis with HLA-DR4 and HLA-DR2 alleles
    • Steere AC, Dwyer E, Winchester R. Association of chronic Lyme arthritis with HLA-DR4 and HLA-DR2 alleles. N Engl J Med 1990; 323: 219-223.
    • (1990) N Engl J Med , vol.323 , pp. 219-223
    • Steere, A.C.1    Dwyer, E.2    Winchester, R.3
  • 53
    • 4043121901 scopus 로고    scopus 로고
    • Genetic association of cutaneous neonatal lupus with HLA class II and tumor necrosis factor alpha: implications for pathogenesis
    • Clancy RM, Backer CB, Yin X et al. Genetic association of cutaneous neonatal lupus with HLA class II and tumor necrosis factor alpha: implications for pathogenesis. Arthritis Rheum 2004; 50: 2598-2603.
    • (2004) Arthritis Rheum , vol.50 , pp. 2598-2603
    • Clancy, R.M.1    Backer, C.B.2    Yin, X.3
  • 55
    • 0023500817 scopus 로고
    • The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis
    • Gregersen PK, Silver J, Winchester RJ. The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum 1987; 30: 1205-1213.
    • (1987) Arthritis Rheum , vol.30 , pp. 1205-1213
    • Gregersen, P.K.1    Silver, J.2    Winchester, R.J.3
  • 56
    • 73249122274 scopus 로고    scopus 로고
    • Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases
    • Rioux JD, Goyette P, Vyse TJ et al. Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases. Proc Natl Acad Sci USA 2009; 106: 18680-18685.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 18680-18685
    • Rioux, J.D.1    Goyette, P.2    Vyse, T.J.3
  • 57
    • 84867743733 scopus 로고    scopus 로고
    • GWAS implicates a role for quantitative immune traits and threshold effects in risk for human autoimmune disorders
    • Gregersen PK, Diamond B, Plenge RM. GWAS implicates a role for quantitative immune traits and threshold effects in risk for human autoimmune disorders. Curr Opin Immunol 2012; 24: 538-543.
    • (2012) Curr Opin Immunol , vol.24 , pp. 538-543
    • Gregersen, P.K.1    Diamond, B.2    Plenge, R.M.3
  • 58
    • 0033504174 scopus 로고    scopus 로고
    • DNA typing of maternal HLA in congenital complete heart block: comparison with systemic lupus erythematosus and primary Sjogren's syndrome
    • Colombo G, Brucato A, Coluccio E et al. DNA typing of maternal HLA in congenital complete heart block: comparison with systemic lupus erythematosus and primary Sjogren's syndrome. Arthritis Rheum 1999; 42: 1757-1764.
    • (1999) Arthritis Rheum , vol.42 , pp. 1757-1764
    • Colombo, G.1    Brucato, A.2    Coluccio, E.3
  • 59
    • 0032969961 scopus 로고    scopus 로고
    • Role of HLA in congenital heart block: susceptibility alleles in mothers
    • Siren MK, Julkunen H, Kaaja R, Kurki P, Koskimies S. Role of HLA in congenital heart block: susceptibility alleles in mothers. Lupus 1999; 8: 52-59.
    • (1999) Lupus , vol.8 , pp. 52-59
    • Siren, M.K.1    Julkunen, H.2    Kaaja, R.3    Kurki, P.4    Koskimies, S.5
  • 60
    • 0024326639 scopus 로고
    • Congenital heart block immunogenetics. Evidence of an additional role of HLA class III antigens and independence of Ro autoantibodies
    • Arnaiz-Villena A, Vazquez-Rodriguez JJ, Vicario JL et al. Congenital heart block immunogenetics. Evidence of an additional role of HLA class III antigens and independence of Ro autoantibodies. Arthritis Rheum 1989; 32: 1421-1426.
    • (1989) Arthritis Rheum , vol.32 , pp. 1421-1426
    • Arnaiz-Villena, A.1    Vazquez-Rodriguez, J.J.2    Vicario, J.L.3
  • 62
    • 0028032269 scopus 로고
    • Inheritance of MHC class II genes in IDDM studied in population-based affected and control families
    • Kockum I, Wassmuth R, Holmberg E, Michelsen B, Lernmark A. Inheritance of MHC class II genes in IDDM studied in population-based affected and control families. Diabetologia 1994; 37: 1105-1112.
    • (1994) Diabetologia , vol.37 , pp. 1105-1112
    • Kockum, I.1    Wassmuth, R.2    Holmberg, E.3    Michelsen, B.4    Lernmark, A.5
  • 63
    • 85007115996 scopus 로고    scopus 로고
    • Anti-Ro52/p200 antibodies induce heart block in rodents upon transfer during gestation in a time- and dose-dependent manner
    • Ambrosi A, Dzikaite V, Strandberg L, Kuchroo VK, Wahren-Herlenius M. Anti-Ro52/p200 antibodies induce heart block in rodents upon transfer during gestation in a time- and dose-dependent manner. Scand J Immunol 2010; 72: 264-265.
    • (2010) Scand J Immunol , vol.72 , pp. 264-265
    • Ambrosi, A.1    Dzikaite, V.2    Strandberg, L.3    Kuchroo, V.K.4    Wahren-Herlenius, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.