Kinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancer

Oncotarget

Volumn 5, Issue 10, 2014, Pages 3145-3158

  Al Ejeh, Fares ^a   Miranda, Mariska ^a,b   Shi, Wei ^a   Simpson, Peter T ^c   Song, Sarah ^b   Vargas, Ana Cristina ^c   Saunus, Jodi M ^c   Smart, Chanel E ^c   Mariasegaram, Mythily ^c   Wiegmans, Adrian P ^a   Chenevix Trench, Georgia ^a   Lakhani, Sunil R ^b,c,d   Khanna, Kum Kum ^a,b  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c UNIVERSITY OF QUEENSLAND   (Australia)

^d ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

Author keywords

Breast cancer; Cancer heterogeneity; Kinome; Targeted therapy; TNBC

Indexed keywords

DOCETAXEL; DOXORUBICIN; HEAT SHOCK PROTEIN 90; LUMINESPIB; MITOGEN ACTIVATED PROTEIN KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG; XMD 8 92; PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER CELL LINE; CANCER GROWTH; CANCER PROGNOSIS; CARCINOGENICITY; CELL SURVIVAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENTIATION; DRUG SENSITIVITY; ENZYME INHIBITION; FEMALE; GENE EXPRESSION PROFILING; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MOLECULARLY TARGETED THERAPY; MOUSE; NONHUMAN; PRIMARY TUMOR; PROTEIN MICROARRAY; PROTEIN PHOSPHORYLATION; PROTEOMICS; TRANSCRIPTOMICS; TRIPLE NEGATIVE BREAST CANCER; UPREGULATION; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; CLUSTER ANALYSIS; METABOLISM; NUDE MOUSE;

ANIMALS; CLUSTER ANALYSIS; FEMALE; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; MOLECULAR TARGETED THERAPY; PROTEIN ARRAY ANALYSIS; PROTEIN KINASES; PROTEOMICS; TRIPLE NEGATIVE BREAST NEOPLASMS;

EID: 84902072983     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.1865     Document Type: Article

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