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Volumn 7, Issue 11, 2011, Pages 818-826

Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; HEAT SHOCK PROTEIN 90; ONCOPROTEIN; PU H 71; STAT5 PROTEIN; UNCLASSIFIED DRUG;

EID: 80054851888     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.670     Document Type: Article
Times cited : (231)

References (46)
  • 1
    • 55549101623 scopus 로고    scopus 로고
    • DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome
    • Ley, T.J. et al. DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome. Nature 456, 66-72 (2008).
    • (2008) Nature , vol.456 , pp. 66-72
    • Ley, T.J.1
  • 2
    • 52949127312 scopus 로고    scopus 로고
    • An integrated genomic analysis of human glioblastoma multiforme
    • Parsons, D.W. et al. An integrated genomic analysis of human glioblastoma multiforme. Science 321, 1807-1812 (2008).
    • (2008) Science , vol.321 , pp. 1807-1812
    • Parsons, D.W.1
  • 3
    • 77955976922 scopus 로고    scopus 로고
    • The grand challenge to decipher the cancer proteome
    • Hanash, S. & Taguchi, A. The grand challenge to decipher the cancer proteome. Nat. Rev. Cancer 10, 652-660 (2010).
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 652-660
    • Hanash, S.1    Taguchi, A.2
  • 4
    • 77955942384 scopus 로고    scopus 로고
    • Functional proteomics to dissect tyrosine kinase signalling pathways in cancer
    • Kolch, W. & Pitt, A. Functional proteomics to dissect tyrosine kinase signalling pathways in cancer. Nat. Rev. Cancer 10, 618-629 (2010).
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 618-629
    • Kolch, W.1    Pitt, A.2
  • 5
    • 77955983759 scopus 로고    scopus 로고
    • Activity-based protein profiling for biochemical pathway discovery in cancer
    • Nomura, D.K., Dix, M.M. & Cravatt, B.F. Activity-based protein profiling for biochemical pathway discovery in cancer. Nat. Rev. Cancer 10, 630-638 (2010).
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 630-638
    • Nomura, D.K.1    Dix, M.M.2    Cravatt, B.F.3
  • 6
    • 66149095910 scopus 로고    scopus 로고
    • Charting the molecular network of the drug target bcr-abl
    • USA
    • Brehme, M. et al. Charting the molecular network of the drug target Bcr-Abl. Proc. Natl. Acad. Sci. USA 106, 7414-7419 (2009).
    • (2009) Proc. Natl. Acad. Sci. , vol.106 , pp. 7414-7419
    • Brehme, M.1
  • 7
    • 73349139521 scopus 로고    scopus 로고
    • Phosphoproteomics and cancer research
    • Ashman, K. & Villar, E.L. Phosphoproteomics and cancer research. Clin. Transl. Oncol. 11, 356-362 (2009).
    • (2009) Clin. Transl. Oncol. , vol.11 , pp. 356-362
    • Ashman, K.1    Villar, E.L.2
  • 8
    • 75149177573 scopus 로고    scopus 로고
    • Hsp90 and co-chaperones twist the functions of diverse client proteins
    • Zuehlke, A. & Johnson, J.L. Hsp90 and co-chaperones twist the functions of diverse client proteins. Biopolymers 93, 211-217 (2010).
    • (2010) Biopolymers , vol.93 , pp. 211-217
    • Zuehlke, A.1    Johnson, J.L.2
  • 9
    • 35348890981 scopus 로고    scopus 로고
    • Drugging the cancer chaperone HSP90: Combinatorial therapeutic exploitation of oncogene addiction and tumor stress
    • DOI 10.1196/annals.1391.012, Stress Responses
    • Workman, P., Burrows, F., Neckers, L. & Rosen, N. Drugging the cancer chaperone HSP90: combinatorial therapeutic exploitation of oncogene addiction and tumor stress. Ann. NY Acad. Sci. 1113, 202-216 (2007). (Pubitemid 350015011)
    • (2007) Annals of the New York Academy of Sciences , vol.1113 , pp. 202-216
    • Workman, P.1    Burrows, F.2    Neckers, L.3    Rosen, N.4
  • 11
    • 77952544010 scopus 로고    scopus 로고
    • ATPase inhibitors of heat-shock protein 90 second season
    • Janin, Y.L. ATPase inhibitors of heat-shock protein 90, second season. Drug Discov. Today 15, 342-353 (2010).
    • (2010) Drug Discov. Today , vol.15 , pp. 342-353
    • Janin, Y.L.1
  • 13
    • 28244444919 scopus 로고    scopus 로고
    • Activated B-RAF is an Hsp90 client protein that is targeted by the anticancer drug 17-allylamino-17-demethoxygeldanamycin
    • DOI 10.1158/0008-5472.CAN-05-2632
    • da Rocha Dias, S. et al. Activated B-RAF is an Hsp90 client protein that is targeted by the anticancer drug 17-allylamino-17-demethoxygeldanamycin. Cancer Res. 65, 10686-10691 (2005). (Pubitemid 41713335)
    • (2005) Cancer Research , vol.65 , Issue.23 , pp. 10686-10691
    • Da Rocha Dias, S.1    Friedlos, F.2    Light, Y.3    Springer, C.4    Workman, P.5    Marais, R.6
  • 15
    • 74249105371 scopus 로고    scopus 로고
    • Purine-scaffold hsp90 inhibitors
    • Taldone, T. & Chiosis, G. Purine-scaffold hsp90 inhibitors. Curr. Top. Med. Chem. 9, 1436-1446 (2009).
    • (2009) Curr. Top. Med. Chem. , vol.9 , pp. 1436-1446
    • Taldone, T.1    Chiosis, G.2
  • 16
    • 43549102208 scopus 로고    scopus 로고
    • HSP90: The Rosetta stone for cellular protein dynamics?
    • Dezwaan, D.C. & Freeman, B.C. HSP90: the Rosetta stone for cellular protein dynamics? Cell Cycle 7, 1006-1012 (2008). (Pubitemid 351679833)
    • (2008) Cell Cycle , vol.7 , Issue.8 , pp. 1006-1012
    • DeZwaan, D.C.1    Freeman, B.C.2
  • 17
    • 14644425319 scopus 로고    scopus 로고
    • Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia
    • DOI 10.1038/nrc1567
    • Ren, R. Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia. Nat. Rev. Cancer 5, 172-183 (2005). (Pubitemid 40314949)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.3 , pp. 172-183
    • Ren, R.1
  • 18
    • 77954594460 scopus 로고    scopus 로고
    • BCR-ABL: A multi-faceted promoter of DNA mutation in chronic myelogeneous leukemia
    • Burke, B.A. & Carroll, M. BCR-ABL: a multi-faceted promoter of DNA mutation in chronic myelogeneous leukemia. Leukemia 24, 1105-1112 (2010).
    • (2010) Leukemia , vol.24 , pp. 1105-1112
    • Burke, B.A.1    Carroll, M.2
  • 19
    • 34848926209 scopus 로고    scopus 로고
    • Diverse cellular functions of the Hsp90 molecular chaperone uncovered using systems approaches
    • DOI 10.1016/j.cell.2007.07.036, PII S0092867407009749
    • McClellan, A.J. et al. Diverse cellular functions of the Hsp90 molecular chaperone uncovered using systems approaches. Cell 131, 121-135 (2007). (Pubitemid 47498528)
    • (2007) Cell , vol.131 , Issue.1 , pp. 121-135
    • McClellan, A.J.1    Xia, Y.2    Deutschbauer, A.M.3    Davis, R.W.4    Gerstein, M.5    Frydman, J.6
  • 20
    • 77955443001 scopus 로고    scopus 로고
    • Critical roles for mTORC2-and rapamycin-insensitive mTORC1-complexes in growth and survival of BCR-ABL-expressing leukemic cells
    • USA
    • Carayol, N. et al. Critical roles for mTORC2-and rapamycin-insensitive mTORC1-complexes in growth and survival of BCR-ABL-expressing leukemic cells. Proc. Natl. Acad. Sci. USA 107, 12469-12474 (2010).
    • (2010) Proc. Natl. Acad. Sci. , vol.107 , pp. 12469-12474
    • Carayol, N.1
  • 21
    • 33847743064 scopus 로고    scopus 로고
    • hvps34, an ancient player, enters a growing game: mTOR Complex1/S6K1 signaling
    • DOI 10.1016/j.ceb.2007.02.019, PII S0955067407000312
    • Nobukuni, T., Kozma, S.C. & Thomas, G. hvps34, an ancient player, enters a growing game: mTOR Complex1/S6K1 signaling. Curr. Opin. Cell Biol. 19, 135-141 (2007). (Pubitemid 46386413)
    • (2007) Current Opinion in Cell Biology , vol.19 , Issue.2 , pp. 135-141
    • Nobukuni, T.1    Kozma, S.C.2    Thomas, G.3
  • 23
    • 39049183044 scopus 로고    scopus 로고
    • Regulation and function of IKK and IKK-related kinases
    • Häcker, H. & Karin, M. Regulation and function of IKK and IKK-related kinases. Sci. STKE 2006, re13 (2006).
    • (2006) Sci. STKE 2006
    • Häcker, H.1    Karin, M.2
  • 25
    • 32544452686 scopus 로고    scopus 로고
    • Involvement of SLP-65 and Btk in tumor suppression and malignant transformation of pre-B cells
    • DOI 10.1016/j.smim.2005.10.002, PII S1044532305000849, The Origin of Dignals Predicting Life and Development of B Cell Precursors: Inside Out or Outside In?
    • Hendriks, R.W. & Kersseboom, R. Involvement of SLP-65 and Btk in tumor suppression and malignant transformation of pre-B cells. Semin. Immunol. 18, 67-76 (2006). (Pubitemid 43238338)
    • (2006) Seminars in Immunology , vol.18 , Issue.1 , pp. 67-76
    • Hendriks, R.W.1    Kersseboom, R.2
  • 27
    • 0036493771 scopus 로고    scopus 로고
    • Calpain is a signal transducer and activator of transcription (STAT) 3 and STAT5 protease
    • DOI 10.1182/blood.V99.5.1850
    • Oda, A., Wakao, H. & Fujita, H. Calpain is a signal transducer and activator of transcription (STAT) 3 and STAT5 protease. Blood 99, 1850-1852 (2002). (Pubitemid 34533062)
    • (2002) Blood , vol.99 , Issue.5 , pp. 1850-1852
    • Oda, A.1    Wakao, H.2    Fujita, H.3
  • 28
    • 45549108898 scopus 로고    scopus 로고
    • Activated Ca2+calmodulin-dependent protein kinase IIgamma is a critical regulator of myeloid leukemia cell proliferation
    • Si, J. & Collins, S.J. Activated Ca2+/calmodulin-dependent protein kinase IIgamma is a critical regulator of myeloid leukemia cell proliferation. Cancer Res. 68, 3733-3742 (2008).
    • (2008) Cancer Res. , vol.68 , pp. 3733-3742
    • Si, J.1    Collins, S.J.2
  • 29
    • 0028875460 scopus 로고
    • Increased tyrosine phosphorylation of focal adhesion proteins in myeloid cell lines expressing p210BCR ABL
    • Salgia, R. et al. Increased tyrosine phosphorylation of focal adhesion proteins in myeloid cell lines expressing p210BCR/ABL. Oncogene 11, 1149-1155 (1995).
    • (1995) Oncogene , vol.11 , pp. 1149-1155
    • Salgia, R.1
  • 30
    • 65649152031 scopus 로고    scopus 로고
    • FAK silencing inhibits leukemogenesis in BCR ABL-transformed hematopoietic cells
    • Le, Y. et al. FAK silencing inhibits leukemogenesis in BCR/ABL-transformed hematopoietic cells. Am. J. Hematol. 84, 273-278 (2009).
    • (2009) Am. J. Hematol. , vol.84 , pp. 273-278
    • Le, Y.1
  • 31
    • 0027312772 scopus 로고
    • The role of MYC in transformation by BCR-ABL
    • Sawyers, C.L. The role of myc in transformation by Bcr-Abl. Leuk. Lymphoma 11, 45-46 (1993). (Pubitemid 23274135)
    • (1993) Leukemia and Lymphoma , vol.11 , Issue.SUPPL. 1 , pp. 45-46
    • Sawyers, C.L.1
  • 32
    • 76249087423 scopus 로고    scopus 로고
    • TGF-beta-FOXO signaling maintains leukemia-initiating cells in chronic myeloid leukemia
    • Naka, K. et al. TGF-beta-FOXO signaling maintains leukemia-initiating cells in chronic myeloid leukemia. Nature 463, 676-680 (2010).
    • (2010) Nature , vol.463 , pp. 676-680
    • Naka, K.1
  • 33
    • 58149295717 scopus 로고    scopus 로고
    • Protein arginine methylation in mammals: Who what and why
    • Bedford, M.T. & Clarke, S.G. Protein arginine methylation in mammals: who, what, and why. Mol. Cell 33, 1-13 (2009).
    • (2009) Mol. Cell , vol.33 , pp. 1-13
    • Bedford, M.T.1    Clarke, S.G.2
  • 35
    • 77951030170 scopus 로고    scopus 로고
    • Enhanced sensitivity of pancreatic cancer cells to concurrent inhibition of aberrant signal transducer and activator of transcription 3 and epidermal growth factor receptor or src
    • Jaganathan, S., Yue, P. & Turkson, J. Enhanced sensitivity of pancreatic cancer cells to concurrent inhibition of aberrant signal transducer and activator of transcription 3 and epidermal growth factor receptor or Src. J. Pharmacol. Exp. Ther. 333, 373-381 (2010).
    • (2010) J. Pharmacol. Exp. Ther. , vol.333 , pp. 373-381
    • Jaganathan, S.1    Yue, P.2    Turkson, J.3
  • 36
    • 54249162351 scopus 로고    scopus 로고
    • Targeted polypharmacology: Discovery of dual inhibitors of tyrosine and phosphoinositide kinases
    • Apsel, B. et al. Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nat. Chem. Biol. 4, 691-699 (2008).
    • (2008) Nat. Chem. Biol. , vol.4 , pp. 691-699
    • Apsel, B.1
  • 37
    • 0041466445 scopus 로고    scopus 로고
    • Specific targeted therapy of chronic myelogenous leukemia with imatinib
    • DOI 10.1124/pr.55.3.4
    • Deininger, M.W. & Druker, B.J. Specific targeted therapy of chronic myelogenous leukemia with imatinib. Pharmacol. Rev. 55, 401-423 (2003). (Pubitemid 37013211)
    • (2003) Pharmacological Reviews , vol.55 , Issue.3 , pp. 401-423
    • Deininger, M.W.N.1    Druker, B.J.2
  • 38
    • 34547957796 scopus 로고    scopus 로고
    • Flesh and blood: The story of Vav1, a gene that signals in hematopoietic cells but can be transforming in human malignancies
    • DOI 10.1016/j.canlet.2007.04.015, PII S0304383507002157
    • Katzav, S. Flesh and blood: the story of Vav1, a gene that signals in hematopoietic cells but can be transforming in human malignancies. Cancer Lett. 255, 241-254 (2007). (Pubitemid 47268643)
    • (2007) Cancer Letters , vol.255 , Issue.2 , pp. 241-254
    • Katzav, S.1
  • 39
    • 53149118242 scopus 로고    scopus 로고
    • The Hsp90 chaperone machinery regulates signaling by modulating ligand binding clefts
    • Pratt, W.B., Morishima, Y. & Osawa, Y. The Hsp90 chaperone machinery regulates signaling by modulating ligand binding clefts. J. Biol. Chem. 283, 22885-22889 (2008).
    • (2008) J. Biol. Chem. , vol.283 , pp. 22885-22889
    • Pratt, W.B.1    Morishima, Y.2    Osawa, Y.3
  • 40
    • 0033178667 scopus 로고    scopus 로고
    • STAT5 activation by BCR-Abl contributes to transformation of K562 leukemia cells
    • de Groot, R.P., Raaijmakers, J.A., Lammers, J.W., Jove, R. & Koenderman, L. STAT5 activation by BCR-Abl contributes to transformation of K562 leukemia cells. Blood 94, 1108-1112 (1999). (Pubitemid 29361844)
    • (1999) Blood , vol.94 , Issue.3 , pp. 1108-1112
    • De Groot, R.P.1    Raaijmakers, J.A.M.2    Lammers, J.-W.J.3    Jove, R.4    Koenderman, L.5
  • 41
    • 0033863883 scopus 로고    scopus 로고
    • The heat shock protein 90 antagonist geldanamycin alters chaperone association with p210(bcr-abl) and v-src proteins before their degradation by the proteasome
    • An, W.G., Schulte, T.W. & Neckers, L.M. The heat shock protein 90 antagonist geldanamycin alters chaperone association with p210bcr-abl and v-src proteins before their degradation by the proteasome. Cell Growth Differ. 11, 355-360 (2000). (Pubitemid 30619563)
    • (2000) Cell Growth and Differentiation , vol.11 , Issue.7 , pp. 355-360
    • An, W.G.1    Schulte, T.W.2    Neckers, L.M.3
  • 43
    • 42649118836 scopus 로고    scopus 로고
    • Protein tyrosine phosphatases in the JAK/STAT pathway
    • DOI 10.2741/3051
    • Xu, D. & Qu, C.K. Protein tyrosine phosphatases in the JAK/STAT pathway. Front. Biosci. 13, 4925-4932 (2008). (Pubitemid 351599646)
    • (2008) Frontiers in Bioscience , vol.13 , Issue.13 , pp. 4925-4932
    • Xu, D.1    Qu, C.-K.2
  • 44
    • 33750040230 scopus 로고    scopus 로고
    • Structure, function, and regulation of STAT proteins
    • DOI 10.1039/b606246f
    • Lim, C.P. & Cao, X. Structure, function and regulation of STAT proteins. Mol. Biosyst. 2, 536-550 (2006). (Pubitemid 44583902)
    • (2006) Molecular BioSystems , vol.2 , Issue.11 , pp. 536-550
    • Lim, C.P.1    Cao, X.2
  • 45
    • 9244243110 scopus 로고    scopus 로고
    • STATs as critical mediators of signal transduction and transcription: Lessons learned from STAT5
    • DOI 10.1016/j.cytogfr.2004.09.001, PII S1359610104000759
    • Paukku, K. & Silvennoinen, O. STATs as critical mediators of signal transduction and transcription: lessons learned from STAT5. Cytokine Growth Factor Rev. 15, 435-455 (2004). (Pubitemid 39550454)
    • (2004) Cytokine and Growth Factor Reviews , vol.15 , Issue.6 , pp. 435-455
    • Paukku, K.1    Silvennoinen, O.2
  • 46
    • 69249136243 scopus 로고    scopus 로고
    • Target profiling of small molecules by chemical proteomics
    • Rix, U. & Superti-Furga, G. Target profiling of small molecules by chemical proteomics. Nat. Chem. Biol. 5, 616-624 (2009).
    • (2009) Nat. Chem. Biol. , vol.5 , pp. 616-624
    • Rix, U.1    Superti-Furga, G.2


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