메뉴 건너뛰기




Volumn , Issue , 2003, Pages 145-173

Public sources of mutagenicity and carcinogenicity data: Use in structure-activity relationship models

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84902039341     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1201/9780203010822     Document Type: Chapter
Times cited : (22)

References (51)
  • 2
    • 0036491315 scopus 로고    scopus 로고
    • AI and SAR approaches for predicting chemical carcinogenicity: Survey and status report
    • Richard, A.M. and Benigni, R., AI and SAR approaches for predicting chemical carcinogenicity: survey and status report, SAR QSAR Environ. Toxicol., 13, 1, 2002.
    • (2002) SAR QSAR Environ. Toxicol. , vol.13 , pp. 1
    • Richard, A.M.1    Benigni, R.2
  • 3
    • 0034622073 scopus 로고    scopus 로고
    • Potential health effects of drinking water disinfection by-products using quantitative structure toxicity relationship
    • Moudgal, C.J., Lipscomb, J.C., and Bruce, R.M., Potential health effects of drinking water disinfection by-products using quantitative structure toxicity relationship, Toxicology, 147, 109, 2000.
    • (2000) Toxicology , vol.147 , pp. 109
    • Moudgal, C.J.1    Lipscomb, J.C.2    Bruce, R.M.3
  • 4
    • 0023226007 scopus 로고
    • A structure-activity prediction model of carcinogenicity based on NCI/NTP assays and food additives
    • Enslein, K. et al., A structure-activity prediction model of carcinogenicity based on NCI/NTP assays and food additives, Toxicol. Indus. Health, 3, 267, 1987.
    • (1987) Toxicol. Indus. Health , vol.3 , pp. 267
    • Enslein, K.1
  • 5
    • 0036179149 scopus 로고    scopus 로고
    • Use of mechanism-based structure-activity relationships analysis in carcinogenic potential ranking for drinking water disinfection by-products
    • Woo, Y.-T. et al., Use of mechanism-based structure-activity relationships analysis in carcinogenic potential ranking for drinking water disinfection by-products, Environ. Health Perspect., 110 (suppl. 1), 75, 2002.
    • (2002) Environ. Health Perspect. , vol.110 , pp. 75
    • Woo, Y.-T.1
  • 6
    • 0021529312 scopus 로고
    • Artificial intelligence approach to structure-activity studies. Computer automated structure evaluation of biological activity of organic molecules
    • Klopman, G., Artificial intelligence approach to structure-activity studies. Computer automated structure evaluation of biological activity of organic molecules, J. Am. Chem. Soc., 106, 7315, 1984.
    • (1984) J. Am. Chem. Soc. , vol.106 , pp. 7315
    • Klopman, G.1
  • 7
    • 0026778110 scopus 로고
    • MULTICASE 1: A hierarchical computer automated structure evaluation program
    • Klopman, G., MULTICASE 1: a hierarchical computer automated structure evaluation program, Quant. Struct.-Act. Relat., 11, 176, 1992.
    • (1992) Quant. Struct.-Act. Relat. , vol.11 , pp. 176
    • Klopman, G.1
  • 8
    • 0028157137 scopus 로고
    • Approaches to SAR in carcinogenesis and mutagenesis. Prediction of carcinogenicity/mutagenicity using MULTI-CASE
    • Klopman, G. and Rosenkranz, H.S., Approaches to SAR in carcinogenesis and mutagenesis. Prediction of carcinogenicity/mutagenicity using MULTI-CASE, Mutat. Res., 305, 33, 1994.
    • (1994) Mutat. Res. , vol.305 , pp. 33
    • Klopman, G.1    Rosenkranz, H.S.2
  • 9
    • 0028873540 scopus 로고
    • Predicting chemical carcinogenesis in rodents: The state of the art in light of a comparative exercise
    • Benigni, R., Predicting chemical carcinogenesis in rodents: the state of the art in light of a comparative exercise, Mutat. Res., 334, 103, 1995.
    • (1995) Mutat. Res. , vol.334 , pp. 103
    • Benigni, R.1
  • 10
    • 0030941637 scopus 로고    scopus 로고
    • Computational predictive programs (expert systems) in toxicology
    • Benfenati, E. and Gini, G., Computational predictive programs (expert systems) in toxicology, Toxicology, 119, 213, 1997.
    • (1997) Toxicology , vol.119 , pp. 213
    • Benfenati, E.1    Gini, G.2
  • 11
    • 0030755884 scopus 로고    scopus 로고
    • The first U.S. National Toxicology Program exercise on the prediction of rodent carcinogenicity: Definitive results
    • Benigni, R., The first U.S. National Toxicology Program exercise on the prediction of rodent carcinogenicity: definitive results, Mutat. Res., 387, 35, 1997.
    • (1997) Mutat. Res. , vol.387 , pp. 35
    • Benigni, R.1
  • 12
    • 0031698019 scopus 로고    scopus 로고
    • Quantitative structure-based modeling applied to characterization and prediction of chemical toxicity
    • Benigni, R. and Richard, A.M., Quantitative structure-based modeling applied to characterization and prediction of chemical toxicity, Methods, 14, 264, 1998.
    • (1998) Methods , vol.14 , pp. 264
    • Benigni, R.1    Richard, A.M.2
  • 13
    • 0032565550 scopus 로고    scopus 로고
    • Structure-based methods for predicting mutagenicity and carcinogenicity: Are we there yet?
    • Richard, A.M., Structure-based methods for predicting mutagenicity and carcinogenicity: are we there yet?, Mutat. Res., 400, 493, 1998.
    • (1998) Mutat. Res. , vol.400 , pp. 493
    • Richard, A.M.1
  • 14
    • 0037204541 scopus 로고    scopus 로고
    • Computer systems for the prediction of toxicity: An update
    • Greene, N., Computer systems for the prediction of toxicity: an update, Adv. Drug Deliv. Rev., 54, 417, 2002.
    • (2002) Adv. Drug Deliv. Rev. , vol.54 , pp. 417
    • Greene, N.1
  • 15
    • 0035847124 scopus 로고    scopus 로고
    • Toxicology information from U.S. government agencies
    • Brinkhuis, R.P., Toxicology information from U.S. government agencies, Toxicology, 157, 25, 2001.
    • (2001) Toxicology , vol.157 , pp. 25
    • Brinkhuis, R.P.1
  • 16
    • 0036242073 scopus 로고    scopus 로고
    • Improving structure-linked access to publicly available chemical toxicity information
    • Richard, A.M., Williams, C.R., and Cariello, N.F., Improving structure-linked access to publicly available chemical toxicity information, Curr. Opin. Drug Discov. Devel., 5, 136, 2002.
    • (2002) Curr. Opin. Drug Discov. Devel. , vol.5 , pp. 136
    • Richard, A.M.1    Williams, C.R.2    Cariello, N.F.3
  • 17
    • 0037171690 scopus 로고    scopus 로고
    • Introduction to special issue (part II) on digital information and tools
    • Wexler, P., Introduction to special issue (part II) on digital information and tools, Toxicology, 173, 1, 2002.
    • (2002) Toxicology , vol.173 , pp. 1
    • Wexler, P.1
  • 18
    • 0037171671 scopus 로고    scopus 로고
    • Genetic toxicology: Web resources
    • Young, R.R., Genetic toxicology: web resources, Toxicology, 173, 103, 2002.
    • (2002) Toxicology , vol.173 , pp. 103
    • Young, R.R.1
  • 19
    • 0037171702 scopus 로고    scopus 로고
    • Cancer information resources: Digital and online sources
    • Junghans, T.B., Cancer information resources: digital and online sources, Toxicology, 173, 13, 2002.
    • (2002) Toxicology , vol.173 , pp. 13
    • Junghans, T.B.1
  • 20
    • 0026342472 scopus 로고
    • Current status of the Gene-Tox Program
    • Auletta, A.E. et al., Current status of the Gene-Tox Program. Environ. Health Perspect., 96, 33, 1991.
    • (1991) Environ. Health Perspect. , vol.96 , pp. 33
    • Auletta, A.E.1
  • 21
    • 0000973407 scopus 로고
    • Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U.S. NTP
    • Ashby, J. and Tennant, R.W., Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U.S. NTP, Mutat. Res., 257, 229, 1991.
    • (1991) Mutat. Res. , vol.257 , pp. 229
    • Ashby, J.1    Tennant, R.W.2
  • 22
    • 0001903876 scopus 로고
    • Compendium of abstracts from long-term cancer studies reorted by the National Toxicology Program from 1976 to 1992
    • Selkirk, J.K. and Soward, S.M., Compendium of abstracts from long-term cancer studies reorted by the National Toxicology Program from 1976 to 1992, Environ. Health Perspect., 101, 1, 1993.
    • (1993) Environ. Health Perspect. , vol.101 , pp. 1
    • Selkirk, J.K.1    Soward, S.M.2
  • 23
    • 0000608085 scopus 로고    scopus 로고
    • Application of artificial intelligence and computational methods to predicting toxicity
    • Richard, A.M., Application of artificial intelligence and computational methods to predicting toxicity, Knowledge Eng. Rev., 14, 307, 1999.
    • (1999) Knowledge Eng. Rev. , vol.14 , pp. 307
    • Richard, A.M.1
  • 24
    • 0001383515 scopus 로고    scopus 로고
    • The development and validation of expert systems for predicting toxicity: The report and recommendations of ECVAM/ECB workshop 24
    • Dearden, J.C. et al., The development and validation of expert systems for predicting toxicity: the report and recommendations of ECVAM/ECB workshop 24, Alternative to Laboratory Animals (ATLA), 25, 223, 1997.
    • (1997) Alternative to Laboratory Animals (ATLA) , vol.25 , pp. 223
    • Dearden, J.C.1
  • 26
    • 0032574331 scopus 로고    scopus 로고
    • Identification of ‘genotoxic’ and ʼnon-genotoxic’ alerts for cancer in mice: The carcinogenic potency database
    • Cunningham, A.R. et al., Identification of ‘genotoxic’ and ʼnon-genotoxic’ alerts for cancer in mice: the carcinogenic potency database, Mutat. Res., 398, 1, 1998.
    • (1998) Mutat. Res. , vol.398 , pp. 1
    • Cunningham, A.R.1
  • 27
    • 0042311620 scopus 로고    scopus 로고
    • Identification of structural features and associated mechanisms of action for carcinogens in rats
    • Cunningham, A.R. et al., Identification of structural features and associated mechanisms of action for carcinogens in rats, Mutat. Res., 405, 9, 1998.
    • (1998) Mutat. Res. , vol.405 , pp. 9
    • Cunningham, A.R.1
  • 28
    • 0032458218 scopus 로고    scopus 로고
    • A new highly specific method for predicting the carcinogenic potential of pharmaceuticals in rodents using enhanced MultiCASE QSAR-ES software
    • Matthews, E.J. and Contrera, J.F., A new highly specific method for predicting the carcinogenic potential of pharmaceuticals in rodents using enhanced MultiCASE QSAR-ES software, Regulat. Pharmacol. Toxicol., 28, 242, 1998.
    • (1998) Regulat. Pharmacol. Toxicol. , vol.28 , pp. 242
    • Matthews, E.J.1    Contrera, J.F.2
  • 29
    • 0029803504 scopus 로고    scopus 로고
    • Prediction of the carcinogenicity of a second group of chemicals undergoing carcinogenic testing
    • Zhang, Y.P. et al., Prediction of the carcinogenicity of a second group of chemicals undergoing carcinogenic testing, Environ. Health Perspect., 104, 1045, 1996.
    • (1996) Environ. Health Perspect. , vol.104 , pp. 1045
    • Zhang, Y.P.1
  • 30
    • 0025938503 scopus 로고
    • Chemicals associated with site-specific neoplasia in 1394 long-term carcinogenesis experiments in laboratory rodents
    • Huff, J. et al., Chemicals associated with site-specific neoplasia in 1394 long-term carcinogenesis experiments in laboratory rodents, Environ. Health Perspect., 93, 247, 1991.
    • (1991) Environ. Health Perspect. , vol.93 , pp. 247
    • Huff, J.1
  • 31
    • 0027406601 scopus 로고
    • The influence of chemical structure on the extent and sites of carcinogenesis for 522 rodent carcinogens and 55 different human carcinogen exposures
    • Ashby, J. and Paton, D., The influence of chemical structure on the extent and sites of carcinogenesis for 522 rodent carcinogens and 55 different human carcinogen exposures, Mutat. Res., 286, 3, 1993.
    • (1993) Mutat. Res. , vol.286 , pp. 3
    • Ashby, J.1    Paton, D.2
  • 32
    • 0032511834 scopus 로고    scopus 로고
    • Profiles of chemically-induced tumors in rodents: Quantitative relationships
    • Benigni, R. and Pino, A., Profiles of chemically-induced tumors in rodents: quantitative relationships, Mutat. Res., 421, 93, 1998.
    • (1998) Mutat. Res. , vol.421 , pp. 93
    • Benigni, R.1    Pino, A.2
  • 33
    • 0023257565 scopus 로고
    • Reproducibility of results in ʼnear-replicate’ carcinogenesis bioassays
    • Gold, L.S. et al., Reproducibility of results in ʼnear-replicate’ carcinogenesis bioassays, J. Natl. Cancer Inst., 78, 1149, 1987.
    • (1987) J. Natl. Cancer Inst. , vol.78 , pp. 1149
    • Gold, L.S.1
  • 34
    • 0003134747 scopus 로고    scopus 로고
    • Overview and update of analyses of the carcinogenic potency database
    • Gold, L.S. and Zeiger, E., Eds., CRC Press, Boca Raton, FL
    • Gold, L.S., Sloan, T.H., and Ames, B.N., Overview and update of analyses of the carcinogenic potency database, in Handbook of Carcinogenic Potency and Genotoxicity Databases, Gold, L.S. and Zeiger, E., Eds., CRC Press, Boca Raton, FL, 1997, 661.
    • (1997) Handbook of Carcinogenic Potency and Genotoxicity Databases , pp. 661
    • Gold, L.S.1    Sloan, T.H.2    Ames, B.N.3
  • 35
    • 0033173147 scopus 로고    scopus 로고
    • Supplement to the Carcinogenic Potency Database (CPDB): Results of animal bioassays published in the general literature in 1993 to 1994 and by the National Toxicology Program in 1995 to 1996
    • Gold L.S. et al., Supplement to the Carcinogenic Potency Database (CPDB): results of animal bioassays published in the general literature in 1993 to 1994 and by the National Toxicology Program in 1995 to 1996, Environ. Health Perspect., 107 (suppl. 4), 527, 1999.
    • (1999) Environ. Health Perspect. , vol.107 , pp. 527
    • Gold, L.S.1
  • 36
    • 0035679442 scopus 로고    scopus 로고
    • Compendium of chemical carcinogens by target organ: Results of chronic bioassays in rats, mice, hamsters, dogs, and monkeys
    • Gold, L.S. et al., Compendium of chemical carcinogens by target organ: results of chronic bioassays in rats, mice, hamsters, dogs, and monkeys, Toxicol. Pathol., 29, 639, 2001.
    • (2001) Toxicol. Pathol. , vol.29 , pp. 639
    • Gold, L.S.1
  • 37
    • 0021647476 scopus 로고
    • The TD50: A proposed general convention for the numerical description of the carcinogenic potency of chemicals in chronic-exposure animal experiments
    • Peto, R., The TD50: a proposed general convention for the numerical description of the carcinogenic potency of chemicals in chronic-exposure animal experiments, Environ. Health Perspect., 58, 1, 1984.
    • (1984) Environ. Health Perspect. , vol.58 , pp. 1
    • Peto, R.1
  • 38
    • 0036095371 scopus 로고    scopus 로고
    • Carcinogenicity of the aromatic amines: From structure- activity relationships to mechanisms of action and risk assessment
    • Benigni, R. and Passerini, L., Carcinogenicity of the aromatic amines: from structure- activity relationships to mechanisms of action and risk assessment, Mutat. Res., 511, 191, 2002.
    • (2002) Mutat. Res. , vol.511 , pp. 191
    • Benigni, R.1    Passerini, L.2
  • 39
    • 0035325211 scopus 로고    scopus 로고
    • Data quality in predictive toxicology: Reproducibility of rodent carcinogenicity experiments
    • Gottmann, E. et al., Data quality in predictive toxicology: reproducibility of rodent carcinogenicity experiments, Environ. Health Perspect., 109, 509, 2001.
    • (2001) Environ. Health Perspect. , vol.109 , pp. 509
    • Gottmann, E.1
  • 40
    • 0026324580 scopus 로고
    • Structure-activity relations: Maximizing the usefulness of mutagenicity and carcinogenicity databases
    • Klopman, G. and Rosenkranz, H.S., Structure-activity relations: maximizing the usefulness of mutagenicity and carcinogenicity databases, Environ. Health Perspect., 96, 67, 1991.
    • (1991) Environ. Health Perspect. , vol.96 , pp. 67
    • Klopman, G.1    Rosenkranz, H.S.2
  • 41
    • 0032609573 scopus 로고    scopus 로고
    • Development, characterization, and application of predictivetoxicology models
    • Rosenkranz, H.S. et al., Development, characterization, and application of predictivetoxicology models, SAR QSAR Environ. Res., 10, 277, 1999.
    • (1999) SAR QSAR Environ. Res. , vol.10 , pp. 277
    • Rosenkranz, H.S.1
  • 42
    • 0027280291 scopus 로고
    • An approach for evaluating and increasing the informational content of mutagenicity and clastogenicity data bases
    • Takihi, N. et al., An approach for evaluating and increasing the informational content of mutagenicity and clastogenicity data bases, Mutagenicity, 8, 257, 1993.
    • (1993) Mutagenicity , vol.8 , pp. 257
    • Takihi, N.1
  • 43
    • 0030605174 scopus 로고    scopus 로고
    • Estimation of the optimal database size for structure-activity analyses: The Salmonella mutagenicity data base
    • Liu, M. et al., Estimation of the optimal database size for structure-activity analyses: the Salmonella mutagenicity data base, Mutat. Res., 358, 63, 1996.
    • (1996) Mutat. Res. , vol.358 , pp. 63
    • Liu, M.1
  • 44
    • 0030580221 scopus 로고    scopus 로고
    • Structure-activity and mechanistic relationships: The effects of chemical overlap on the structural overlap in databases of varying size and composition
    • Liu, M. et al., Structure-activity and mechanistic relationships: the effects of chemical overlap on the structural overlap in databases of varying size and composition, Mutat. Res., 372, 79, 1996.
    • (1996) Mutat. Res. , vol.372 , pp. 79
    • Liu, M.1
  • 45
    • 0026056233 scopus 로고
    • Quantification of the predictivity of some shortterm assays for carcinogenicity in rodents
    • Klopman, G. and Rosenkranz, H.S., Quantification of the predictivity of some shortterm assays for carcinogenicity in rodents, Mutat. Res., 253, 237, 1991.
    • (1991) Mutat. Res. , vol.253 , pp. 237
    • Klopman, G.1    Rosenkranz, H.S.2
  • 46
    • 0025221861 scopus 로고
    • Significant differences in the structural basis of the induction of sister chromatid exchanges and chromosomal aberrations in Chinese hamster ovary cells
    • Rosenkranz, H.S. et al., Significant differences in the structural basis of the induction of sister chromatid exchanges and chromosomal aberrations in Chinese hamster ovary cells, Environ. Mol. Mutagen., 16, 149, 1990.
    • (1990) Environ. Mol. Mutagen. , vol.16 , pp. 149
    • Rosenkranz, H.S.1
  • 47
    • 33646963115 scopus 로고    scopus 로고
    • Modeling the mouse lymphoma forward mutational assay: The Gene-Tox program database
    • Grant, S.G. et al., Modeling the mouse lymphoma forward mutational assay: the Gene-Tox program database, Mutat. Res., 465, 201, 2000.
    • (2000) Mutat. Res. , vol.465 , pp. 201
    • Grant, S.G.1
  • 49
    • 0001010920 scopus 로고    scopus 로고
    • Leadscope: Software for exploring large sets of screening data
    • Roberts, G. et al., Leadscope: software for exploring large sets of screening data, J. Chem. Inf. Comput. Sci., 40, 1302, 2000.
    • (2000) J. Chem. Inf. Comput. Sci. , vol.40 , pp. 1302
    • Roberts, G.1
  • 50
    • 0036708529 scopus 로고    scopus 로고
    • Rule extraction from a mutagenicity data set using adaptively grown phylogenetic-like trees
    • Bacha, P.A. et al., Rule extraction from a mutagenicity data set using adaptively grown phylogenetic-like trees, J. Chem. Inf. Comput. Sci., 42, 1104, 2002.
    • (2002) J. Chem. Inf. Comput. Sci. , vol.42 , pp. 1104
    • Bacha, P.A.1
  • 51
    • 0037192325 scopus 로고    scopus 로고
    • Distributed Structure-Searchable Toxicity (DSSTox) public database network: A proposal
    • Richard, A.M. and Williams, C.R., Distributed Structure-Searchable Toxicity (DSSTox) public database network: a proposal, Mutat. Res., 499, 27, 2002.
    • (2002) Mutat. Res. , vol.499 , pp. 27
    • Richard, A.M.1    Williams, C.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.