Role of miR-208 in cardiac fibrosis: Prevention or promotion?

Archives of Medical Research

Volumn 45, Issue 4, 2014, Pages 356-

  Huang, Ying ^a   Xu, Tao ^a   Li, Jun ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; ENDOGLIN; MICRORNA; MICRORNA 208; THYROID HORMONE; THYROXINE; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

CONGESTIVE CARDIOMYOPATHY; DOWN REGULATION; GENE EXPRESSION; HEART MUSCLE FIBROSIS; LETTER; MYOBLAST; NEPHRECTOMY; NONHUMAN; PROTEIN FUNCTION; THORACIC AORTA; UPREGULATION; WILD TYPE;

ANIMALS; MALE; MICRORNAS; MYOCARDIUM; THYROID HORMONES; VENTRICULAR REMODELING;

EID: 84902011530     PISSN: 01884409     EISSN: 18735487     Source Type: Journal    
DOI: 10.1016/j.arcmed.2014.03.010     Document Type: Letter

References (6)

1. Prado-Uribe M.D., Soto-Abraham M.V., Mora-Villalpando C.J., et al. Role of thyroid hormones and mir-208 in myocardial remodeling in 5/6 nephrectomized rats. Arch Med Res 2013, 44:616-622.
2. Satoh M., Minami Y., Takahashi Y., et al. Expression of microRNA-208 is associated with adverse clinical outcomes in human dilated cardiomyopathy. J Card Fail 2010, 16:404-410.
3. Montgomery R.L., Hullinger T.G., Semus H.M., et al. Therapeutic inhibition of miR-208a improves cardiac function and survival during heart failure. Circulation 2011, 124:1537-1547.
4. van Rooij E., Sutherland L.B., Qi X., et al. Control of stress-dependent cardiac growth and gene expression by a microRNA. Science 2007, 316:575-579.
5. Shyu K.G., Wang B.W., Wu G.J., et al. Mechanical stretch via transforming growth factor-beta1 activates microRNA208a to regulate endoglin expression in cultured rat cardiac myoblasts. Eur J Heart Fail 2013, 15:36-45.
6. Wang B.W., Wu G.J., Cheng W.P., et al. MicroRNA-208a increases myocardial fibrosis via endoglin in volume overloading heart. PLoS One 2014, 9:e84188.