메뉴 건너뛰기




Volumn 61, Issue 8, 2014, Pages 1341-1346

The effect of hydroxyurea on compound heterozygotes for sickle cell-hemoglobin D-Punjab-A single centre experience in eastern India

Author keywords

HbSD Punjab; Hydroxyurea; Sickle cell anemia; VOC

Indexed keywords

BILIRUBIN; HEMOGLOBIN; HEMOGLOBIN F; HEMOGLOBIN S; HYDROXYUREA; LACTATE DEHYDROGENASE; TOTAL HEMOGLOBIN; UNCLASSIFIED DRUG;

EID: 84901976230     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.25004     Document Type: Article
Times cited : (25)

References (38)
  • 1
    • 0030663851 scopus 로고    scopus 로고
    • The role of genomics in studying genetic susceptibility to infectious disease
    • Weatherall DJ, Clegg JB, Kwiatkowski D. The role of genomics in studying genetic susceptibility to infectious disease. Genome Res 1997; 7:967-973.
    • (1997) Genome Res , vol.7 , pp. 967-973
    • Weatherall, D.J.1    Clegg, J.B.2    Kwiatkowski, D.3
  • 3
    • 0034889014 scopus 로고    scopus 로고
    • Inherited haemoglobin disorders: An increasing global health problem
    • Weatherall DJ, Clegg JB. Inherited haemoglobin disorders: An increasing global health problem. Bull World Health Organ 2001; 79:704-712.
    • (2001) Bull World Health Organ , vol.79 , pp. 704-712
    • Weatherall, D.J.1    Clegg, J.B.2
  • 5
    • 84904393424 scopus 로고    scopus 로고
    • Fetal hemoglobin and alpha thalassemia modulate the phenotypic expression of HbSD-Punjab
    • doi: 10.1111/ijlh.12165. [Epub ahead of print].
    • Patel DK, Purohit P, Dehury S, et al. Fetal hemoglobin and alpha thalassemia modulate the phenotypic expression of HbSD-Punjab. Int J Lab Hematol 2013; doi: 10.1111/ijlh.12165. [Epub ahead of print].
    • (2013) Int J Lab Hematol
    • Patel, D.K.1    Purohit, P.2    Dehury, S.3
  • 6
    • 0023874785 scopus 로고
    • Facilitation of HbS polymerization by the substitution of Glu for Gln at β121
    • Adachi K, Kim J, Ballas S, et al. Facilitation of HbS polymerization by the substitution of Glu for Gln at β121. J Biol Chem 1988; 263:5607-5610.
    • (1988) J Biol Chem , vol.263 , pp. 5607-5610
    • Adachi, K.1    Kim, J.2    Ballas, S.3
  • 7
    • 84892759639 scopus 로고    scopus 로고
    • Allogeneic transplantation strategies including haploidentical transplantation in sickle cell disease
    • Gluckman E. Allogeneic transplantation strategies including haploidentical transplantation in sickle cell disease. Hematology Am Soc Hematol Educ Program 2013; 2013:370-376.
    • (2013) Hematology Am Soc Hematol Educ Program , vol.2013 , pp. 370-376
    • Gluckman, E.1
  • 8
    • 84873589744 scopus 로고    scopus 로고
    • Candidate sequence variants, fetal hemoglobin in children with sickle cell disease treated with hydroxyurea
    • Green NS, Ender KL, Pashankar F, et al. Candidate sequence variants, fetal hemoglobin in children with sickle cell disease treated with hydroxyurea. PLoS ONE 2013; 8:e55709.
    • (2013) PLoS ONE , vol.8
    • Green, N.S.1    Ender, K.L.2    Pashankar, F.3
  • 9
    • 0021286875 scopus 로고
    • Hydroxyurea enhances fetal hemoglobin production in sickle cell anemia
    • Platt OS, Orkin SH, Dover G, et al. Hydroxyurea enhances fetal hemoglobin production in sickle cell anemia. J Clin Invest 1984; 74:652-656.
    • (1984) J Clin Invest , vol.74 , pp. 652-656
    • Platt, O.S.1    Orkin, S.H.2    Dover, G.3
  • 11
    • 84878516824 scopus 로고    scopus 로고
    • The effect of hydroxcarbamide therapy on survival of children with sickle cell disease
    • Lobo CL, Pinto JF, Nascimento EM, et al. The effect of hydroxcarbamide therapy on survival of children with sickle cell disease. Br J Haematol 2013; 161:852-860.
    • (2013) Br J Haematol , vol.161 , pp. 852-860
    • Lobo, C.L.1    Pinto, J.F.2    Nascimento, E.M.3
  • 12
    • 77950622293 scopus 로고    scopus 로고
    • The effect of prolonged administration of hydroxyurea on morbidity and mortality in adult patients with sickle cell syndromes: Results of a 17-year, single-center trial (LaSHS)
    • Voskaridou E, Christoulas D, Bilalis A, et al. The effect of prolonged administration of hydroxyurea on morbidity and mortality in adult patients with sickle cell syndromes: Results of a 17-year, single-center trial (LaSHS). Blood 2010; 115:2354-2363.
    • (2010) Blood , vol.115 , pp. 2354-2363
    • Voskaridou, E.1    Christoulas, D.2    Bilalis, A.3
  • 13
    • 84862254136 scopus 로고    scopus 로고
    • Hydroxyurea for the treatment of sickle cell disease: Efficacy, barriers, toxicity, and management in children
    • Strouse JJ, Heeney MM. Hydroxyurea for the treatment of sickle cell disease: Efficacy, barriers, toxicity, and management in children. Pediatr Blood Cancer 2012; 59:365-371.
    • (2012) Pediatr Blood Cancer , vol.59 , pp. 365-371
    • Strouse, J.J.1    Heeney, M.M.2
  • 14
    • 0026265702 scopus 로고
    • Sickle cell disease in India
    • Kar BC. Sickle cell disease in India. J Assoc Phys India 1991; 39:954-960.
    • (1991) J Assoc Phys India , vol.39 , pp. 954-960
    • Kar, B.C.1
  • 15
    • 84866596921 scopus 로고    scopus 로고
    • Low dose hydroxyurea is effective in reducing the incidence of painful crisis and frequency of blood transfusion in sickle cell anemia patients from eastern India
    • Patel DK, Mashon RS, Patel S, et al. Low dose hydroxyurea is effective in reducing the incidence of painful crisis and frequency of blood transfusion in sickle cell anemia patients from eastern India. Hemoglobin 2012; 36:409-420.
    • (2012) Hemoglobin , vol.36 , pp. 409-420
    • Patel, D.K.1    Mashon, R.S.2    Patel, S.3
  • 16
    • 84901974253 scopus 로고    scopus 로고
    • Clinical aspects of sickle cell disease in India. 5th Brazilian Symposium for Sickle cell disease and other hemoglobinopathies. Belo Horizonte, Brazil; 2009. Available from:
    • Patel DK. Clinical aspects of sickle cell disease in India. 5th Brazilian Symposium for Sickle cell disease and other hemoglobinopathies. Belo Horizonte, Brazil; 2009. Available from: http://www.cehmob.org.br/simposio/html/english/download.html
    • Patel, D.K.1
  • 17
    • 23244435020 scopus 로고    scopus 로고
    • Clinical and laboratory effects of hydroxyurea in children and adolescents with sickle cell anemia: A Portugese hospital study
    • Braga LB, Ferriira AC, Guimaraes M. Clinical and laboratory effects of hydroxyurea in children and adolescents with sickle cell anemia: A Portugese hospital study. Hemoglobin 2005; 29:171-180.
    • (2005) Hemoglobin , vol.29 , pp. 171-180
    • Braga, L.B.1    Ferriira, A.C.2    Guimaraes, M.3
  • 18
    • 0029025475 scopus 로고
    • Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia
    • Charache S, Terrin ML, Moore RD, et al. Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia. N Engl J Med 1995; 332:1317-1322.
    • (1995) N Engl J Med , vol.332 , pp. 1317-1322
    • Charache, S.1    Terrin, M.L.2    Moore, R.D.3
  • 19
    • 0029618383 scopus 로고
    • Design of the multicenter study of hydroxyurea in sickle cell anemia. Investigators of the Multicenter Study of Hydroxyurea
    • Charache S, Terrin ML, Moore RD, et al. Design of the multicenter study of hydroxyurea in sickle cell anemia. Investigators of the Multicenter Study of Hydroxyurea. Control Clin Trials 1995; 16:432-446.
    • (1995) Control Clin Trials , vol.16 , pp. 432-446
    • Charache, S.1    Terrin, M.L.2    Moore, R.D.3
  • 20
    • 0002713231 scopus 로고
    • Allele-specific enzymatic amplification of β-globin genomic DNA for diagnosis of sickle cell anemia
    • Wu DY, Ugozzoli L, Pal BK, et al. Allele-specific enzymatic amplification of β-globin genomic DNA for diagnosis of sickle cell anemia. Proc Natl Acad Sci USA 1989; 86:2757-2760.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 2757-2760
    • Wu, D.Y.1    Ugozzoli, L.2    Pal, B.K.3
  • 21
    • 0037365343 scopus 로고    scopus 로고
    • Screening and genetic diagnosis of haemoglobin disorders
    • Old JM. Screening and genetic diagnosis of haemoglobin disorders. Blood Rev 2003; 17:43-53.
    • (2003) Blood Rev , vol.17 , pp. 43-53
    • Old, J.M.1
  • 22
    • 79952144554 scopus 로고    scopus 로고
    • β-globin gene haplotypes linked with the Hb D-Punjab [β121(GH4)Glu→Gln. GAA > CAA] mutation in eastern India
    • Patel DK, Mashon RS, Patel S, et al. β-globin gene haplotypes linked with the Hb D-Punjab [β121(GH4)Glu→Gln. GAA > CAA] mutation in eastern India. Hemoglobin 2010; 34:530-537.
    • (2010) Hemoglobin , vol.34 , pp. 530-537
    • Patel, D.K.1    Mashon, R.S.2    Patel, S.3
  • 23
    • 0032875643 scopus 로고    scopus 로고
    • Hb D-Los Angeles associated with Hb S or β-thalassemia in four Mexican Mestizo families
    • Perea FJ, Casas-Castaneda M, Villalobos-Arambula AR, et al. Hb D-Los Angeles associated with Hb S or β-thalassemia in four Mexican Mestizo families. Hemoglobin 1999; 23:231-237.
    • (1999) Hemoglobin , vol.23 , pp. 231-237
    • Perea, F.J.1    Casas-Castaneda, M.2    Villalobos-Arambula, A.R.3
  • 24
    • 72049122687 scopus 로고    scopus 로고
    • Multi centric origin of Hb D-Punjab [b121(GH4)Glu→Gln. GAA > CAA]
    • Yavarian M, Karimi M, Paran F, et al. Multi centric origin of Hb D-Punjab [b121(GH4)Glu→Gln. GAA > CAA]. Hemoglobin 2009; 33:399-405.
    • (2009) Hemoglobin , vol.33 , pp. 399-405
    • Yavarian, M.1    Karimi, M.2    Paran, F.3
  • 25
    • 84901974244 scopus 로고    scopus 로고
    • HbSD-Punjab: Clinical and hematological profile of a rare hemoglobinopathy
    • Epub ahead of print].
    • Oberoi S, Das R, Trehan A, et al. HbSD-Punjab: Clinical and hematological profile of a rare hemoglobinopathy. J Pediatr Hematol Oncol 2013; [Epub ahead of print].
    • (2013) J Pediatr Hematol Oncol
    • Oberoi, S.1    Das, R.2    Trehan, A.3
  • 26
    • 49349104104 scopus 로고    scopus 로고
    • A cell stress signaling model of fetal hemoglobin induction; what doesn't kill red blood cells makes them stronger
    • Mabaera R, West RJ, Conine SJ, et al. A cell stress signaling model of fetal hemoglobin induction; what doesn't kill red blood cells makes them stronger. Exp Hematol 2008; 36:1057-1072.
    • (2008) Exp Hematol , vol.36 , pp. 1057-1072
    • Mabaera, R.1    West, R.J.2    Conine, S.J.3
  • 27
    • 0030893396 scopus 로고    scopus 로고
    • Fetal hemoglobin in sickle cell anemia: Determinants of response to hydroxyurea
    • Steinberg MH, Lu Z-H, Barton FB, et al. Fetal hemoglobin in sickle cell anemia: Determinants of response to hydroxyurea. Blood 1997; 89:1078-1088.
    • (1997) Blood , vol.89 , pp. 1078-1088
    • Steinberg, M.H.1    Lu, Z.-H.2    Barton, F.B.3
  • 28
    • 0028038985 scopus 로고
    • Hydroxyurea affects cell morphology, cation transport, and red blood cell adhesion in cultured vascular endothelial cells
    • Adragna NC, Fonseca P, Lauf PK. Hydroxyurea affects cell morphology, cation transport, and red blood cell adhesion in cultured vascular endothelial cells. Blood 1994; 83:553-556.
    • (1994) Blood , vol.83 , pp. 553-556
    • Adragna, N.C.1    Fonseca, P.2    Lauf, P.K.3
  • 29
    • 10544232620 scopus 로고    scopus 로고
    • A multiparameter analysis of sickle erythrocytes in patients undergoing hydroxyurea therapy
    • Bridges KR, Barabino GD, Brugnara MR, et al. A multiparameter analysis of sickle erythrocytes in patients undergoing hydroxyurea therapy. Blood 1996; 88:4701-4710.
    • (1996) Blood , vol.88 , pp. 4701-4710
    • Bridges, K.R.1    Barabino, G.D.2    Brugnara, M.R.3
  • 30
    • 0030895689 scopus 로고    scopus 로고
    • Decrease of very late activation antigen-4 and CD36 on reticulocytes in sickle cell patients treated with hydroxyurea
    • Styles LA, Lubin B, Vichinsky E, et al. Decrease of very late activation antigen-4 and CD36 on reticulocytes in sickle cell patients treated with hydroxyurea. Blood 1997; 89:2554-2559.
    • (1997) Blood , vol.89 , pp. 2554-2559
    • Styles, L.A.1    Lubin, B.2    Vichinsky, E.3
  • 31
    • 84861094707 scopus 로고    scopus 로고
    • Genotoxicity associated with hydroxyurea exposure in infants with sickle cell anemia: Results from the BABY-HUG phase III clinical trial
    • McGann PT, Flanagan JM, Howard TA, et al. Genotoxicity associated with hydroxyurea exposure in infants with sickle cell anemia: Results from the BABY-HUG phase III clinical trial. Pediatr Blood Cancer 2012; 59:254-257.
    • (2012) Pediatr Blood Cancer , vol.59 , pp. 254-257
    • McGann, P.T.1    Flanagan, J.M.2    Howard, T.A.3
  • 32
    • 37049008636 scopus 로고    scopus 로고
    • DNA damage in blood leukocytes of individuals with sickle cell disease treated with hydroxyurea
    • Friedrisch JR, Pra D, Maluf SW, et al. DNA damage in blood leukocytes of individuals with sickle cell disease treated with hydroxyurea. Mutat Res 2008; 649:213-220.
    • (2008) Mutat Res , vol.649 , pp. 213-220
    • Friedrisch, J.R.1    Pra, D.2    Maluf, S.W.3
  • 33
    • 84869104356 scopus 로고    scopus 로고
    • DNA damage in leukocytes of sickle cell anemia patients is associated with hydroxyurea therapy and with HBB*S haplotype
    • da Silva Rocha LB, Dias Elias DB, Barbosa MC, et al. DNA damage in leukocytes of sickle cell anemia patients is associated with hydroxyurea therapy and with HBB*S haplotype. Mutat Res 2012; 749:48-52.
    • (2012) Mutat Res , vol.749 , pp. 48-52
    • da Silva Rocha, L.B.1    Dias Elias, D.B.2    Barbosa, M.C.3
  • 34
    • 33846983200 scopus 로고    scopus 로고
    • Effect of hydroxyurea on sperm count motility morphology in adult men with sickle cell or myeloproliferative disease
    • Grigg A, Effect of hydroxyurea on sperm count motility morphology in adult men with sickle cell or myeloproliferative disease. Intern Med J 2007; 37:190-192.
    • (2007) Intern Med J , vol.37 , pp. 190-192
    • Grigg, A.1
  • 35
    • 46849120215 scopus 로고    scopus 로고
    • Influence of sickle cell disease and treatment with hydroxyurea on sperm parameters and fertility of human males
    • Berthaut I, Guignedoux G, Kirsch-Noir F, et al. Influence of sickle cell disease and treatment with hydroxyurea on sperm parameters and fertility of human males. Haematologica 2008; 93:988-993.
    • (2008) Haematologica , vol.93 , pp. 988-993
    • Berthaut, I.1    Guignedoux, G.2    Kirsch-Noir, F.3
  • 36
    • 0026631318 scopus 로고
    • Hydroxyurea: Effects on hemoglobin F production in patients with sickle cell anemia
    • Charache S, Dover GJ, Moore RD, et al. Hydroxyurea: Effects on hemoglobin F production in patients with sickle cell anemia. Blood 1992; 79:2555-2565.
    • (1992) Blood , vol.79 , pp. 2555-2565
    • Charache, S.1    Dover, G.J.2    Moore, R.D.3
  • 37
    • 13044277572 scopus 로고    scopus 로고
    • Safety of hydroxyurea in children with sickle cell anemia: Results of the HUG-KIDS study, a phase I/II trial
    • Kinney TR, Helms RW, O'Branski EE, et al. Safety of hydroxyurea in children with sickle cell anemia: Results of the HUG-KIDS study, a phase I/II trial. Blood 1999; 94:1550-1554.
    • (1999) Blood , vol.94 , pp. 1550-1554
    • Kinney, T.R.1    Helms, R.W.2    O'Branski, E.E.3
  • 38
    • 0036096085 scopus 로고    scopus 로고
    • Predictors of fetal hemoglobin response in children with sickle cell anemia receiving hydroxyurea therapy
    • Ware RE, Eggleston B, Redding-Lallinger R, et al. Predictors of fetal hemoglobin response in children with sickle cell anemia receiving hydroxyurea therapy. Blood 2002; 99:10-14.
    • (2002) Blood , vol.99 , pp. 10-14
    • Ware, R.E.1    Eggleston, B.2    Redding-Lallinger, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.