Enhanced cellular uptake and anti-proliferating effect of chitosan hydrochlorides modified genistein loaded NLC on human lens epithelial cells

International Journal of Pharmaceutics

Volumn 471, Issue 1-2, 2014, Pages 118-126

  Zhang, Wenji ^a   Liu, Jinlu ^b   Zhang, Qi ^a   Li, Xuedong ^b   Yu, Shihui ^a   Yang, Xinggang ^a   Kong, Jun ^b   Pan, Weisan ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Cellular uptake; Chitosan hydrochloride; Genistein; NLC

Indexed keywords

CHITOSAN DERIVATIVE; CHITOSAN HYDROCHLORIDE; CLATHRIN; GENISTEIN; LIPOCORTIN 5; NANOCARRIER; NANOSTRUCTURED LIPID CARRIER; SUCROSE; UNCLASSIFIED DRUG; CHITOSAN; DRUG CARRIER; LIPID; NANOPARTICLE; PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE KINASE;

ADSORPTION; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL VIABILITY; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; EMULSION; ENDOCYTOSIS; ENERGY; FLOW CYTOMETRY; GROWTH INHIBITION; HUMAN; HUMAN CELL; LENS CAPSULE; LENS EPITHELIUM; LOW TEMPERATURE; PARTICLE SIZE; PHYSICAL CHEMISTRY; POST LENS CAPSULE; PRIORITY JOURNAL; SURFACE PROPERTY; ZETA POTENTIAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CELL PROLIFERATION; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; EPITHELIUM CELL; LENS; METABOLISM;

APOPTOSIS; CELL LINE; CELL PROLIFERATION; CHITOSAN; DRUG CARRIERS; ENDOCYTOSIS; EPITHELIAL CELLS; FLOW CYTOMETRY; GENISTEIN; HUMANS; LENS, CRYSTALLINE; LIPIDS; NANOPARTICLES; PARTICLE SIZE; PROTEIN KINASE INHIBITORS; PROTEIN-TYROSINE KINASES; SURFACE PROPERTIES;

EID: 84901851719     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.05.030     Document Type: Article

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