Mechanism for neutralizing activity by the anti-CMV gH/gL monoclonal antibody MSL-109

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 22, 2014, Pages 8209-8214

  Fouts, Ashley E ^a   Comps Agrar, Laëtitia ^a   Stengel, Katharina F ^a   Ellerman, Diego ^a   Schoeffler, Allyn J ^a   Warming, Søren ^a   Eaton, Dan L ^a   Feierbach, Becket ^a  

^a GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOMEGALOVIRUS ANTIBODY; EPITOPE; GLYCOPROTEIN; GLYCOPROTEIN B; GLYCOPROTEIN H; GLYCOPROTEIN L; HETERODIMER; NUCLEOTIDE; OLIGOMER; SEVIRUMAB; UNCLASSIFIED DRUG;

ANTIVIRAL RESISTANCE; ARTICLE; BINDING SITE; CELL SURFACE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIMERIZATION; DRUG MECHANISM; EPITHELIUM CELL; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE MUTATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; VIRUS ENTRY; VIRUS INFECTIVITY;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; BASE SEQUENCE; CERCOPITHECUS AETHIOPS; CHO CELLS; COS CELLS; CRICETULUS; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; DIMERIZATION; DRUG RESISTANCE, VIRAL; EPITOPE MAPPING; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MOLECULAR SEQUENCE DATA; VIRAL ENVELOPE PROTEINS;

EID: 84901839214     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1404653111     Document Type: Article

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