Vascular action as the primary mechanism of cognitive effects of cholinergic, CNS-acting drugs, a rat phMRI BOLD study

Journal of Cerebral Blood Flow and Metabolism

Volumn 34, Issue 6, 2014, Pages 995-1000

  Kocsis, Pál ^a   Gyertyán, István ^a   Éles, János ^a   Laszy, Judit ^a   Hegeds, Nikolett ^a   Gajári, Dávid ^a   Deli, Levente ^a   Pozsgay, Zsófia ^a   Dávid, Szabolcs ^a   Tihanyi, Károly ^a  

^a GEDEON RICHTER LTD   (Hungary)

Author keywords

animal models; blood brain barrier; BOLD contrast; cognitive impairment; functional MRI

Indexed keywords

CHOLINERGIC RECEPTOR BLOCKING AGENT; CHOLINESTERASE INHIBITOR; DONEPEZIL; NEOSTIGMINE; SCOPOLAMINE; SCOPOLAMINE BUTYL BROMIDE;

ANIMAL EXPERIMENT; ARTICLE; BLOOD BRAIN BARRIER; BOLD SIGNAL; BRAIN BLOOD FLOW; BRAIN BLOOD VESSEL; BRAIN METABOLISM; CENTRAL NERVOUS SYSTEM; CHOLINERGIC SYSTEM; COGNITIVE DEFECT; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; ENERGY METABOLISM; FUNCTIONAL MAGNETIC RESONANCE IMAGING; LEARNING; NEUROIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SCANNER; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT;

ANIMALS; BLOOD-BRAIN BARRIER; CHOLINESTERASE INHIBITORS; COGNITION; MAGNETIC RESONANCE IMAGING; NEOSTIGMINE; RATS;

EID: 84901838125     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2014.47     Document Type: Article

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