Quantitative detection of circulating tumor DNA in plasma samples by droplet digital pcr.

Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012

Volumn , Issue , 2012, Pages 169-171

  Pekin, D ^a,b   Kotsopoulos, S ^c   Xinyu, L ^c   Atochin, I ^c   Gang, H ^c   Le, Corre D ^a   Benhaim, L ^a   Hutchison, J B ^c   Link, D R ^c   Blons, H ^a   Laurent Puig, P ^a   Taly, V ^a  

^a INSERM   (France)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c RainDance Technologies   (United States)

Author keywords

Cancer biomarkers; Digital PCR; Droplet based microfluidics; Droplets; Microfluidic

Indexed keywords

DISEASES; DROPS; MICROFLUIDICS; POLYMERASE CHAIN REACTION;

CANCER BIOMARKERS; COLORECTAL CANCERS (CRC); DETECTION AND QUANTIFICATIONS; DIGITAL PCR; DROPLET-BASED MICROFLUIDICS; FLUORESCENCE INTENSITIES; FLUORESCENT PROBES; QUANTITATIVE DETECTION;

DIGITAL MICROFLUIDICS;

EID: 84901812649     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (6)

1. Pekin, D., Y. Skhiri, J.-C. Baret, D. Le Corre, L. Mazutis, C. Ben Salem, A.D. Griffiths, P. Laurent-Puig, and V. Taly, DROPLET-BASED MICROFLUIDICS FOR THE QUANTITATIVE DETECTION OF RARE MUTATIONS., in MicroTas 2010, Groningen, pp. 58-60, (2010).
2. Taly, V., D. Pekin, A.E. Abed, and P. Laurent-Puig, Detecting biomarkers with microdroplet technology. Trends in Molecular Medicine, 2012. 18(7), p. 405-16, (2012).
3. Lievre, A., J.B. Bachet, V. Boige, A. Cayre, D. Le Corre, E. Buc, M. Ychou, O. Bouche, B. Landi, C. Louvet, T. Andre, F. Bibeau, M.D. Diebold, P. Rougier, M. Ducreux, G. Tomasic, J.F. Emile, F. Penault-Llorca, and P. Laurent-Puig, KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab. J Clin Oncol, 26(3), p. 374-9, (2008).
4. Pekin, D., Y. Skhiri, J.-C. Baret, D. Le Corre, L. Mazutis, C. Ben Salem, A. El Abed, J.B. Hutchison, D. Link, J.W. Larson, A.D. Griffiths, P. Laurent-Puig, and V. Taly, Multiplex highly sensitive detection of Cancer Biomarkers in biological Samples., in MicroTas. 2011, Seattle, USA, pp. 665-7, (2011).
5. Pekin, D., Y. Skhiri, J.C. Baret, D. Le Corre, L. Mazutis, C. Ben Salem, F. Millot, A. El Harrak, J.B. Hutchison, J.W. Larson, D.R. Link, P. Laurent-Puig, A.D. Griffiths, and V. Taly, Quantitative and sensitive detection of rare mutations using droplet-based microfluidics. Lab Chip, p. 2156-2166, (2011).
6. Zhong, Q., S. Bhattacharya, S. Kotsopoulos, J. Olson, V. Taly, A.D. Griffiths, D.R. Link, and J.W. Larson, Multiplex digital PCR: breaking the one target per color barrier of quantitative PCR. Lab Chip, 11(13), p. 2167-74, (2011).