The effect of autologous activated platelet rich plasma (AA-PRP) injection on pattern hair loss: Clinical and histomorphometric evaluation

BioMed Research International

Volumn 2014, Issue , 2014, Pages

  Cervelli, V ^a   Garcovich, S ^b   Bielli, A ^a   Cervelli, G ^a   Curcio, B C ^a   Scioli, M G ^a   Orlandi, A ^a   Gentile, P ^a,c  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b CATHOLIC UNIVERSITY   (Italy)

^c Institute of Anatomic Pathology University of Rome Tor Vergata ^*  (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

KI 67 ANTIGEN;

ADULT; ARTICLE; AUTOLOGOUS ACTIVATED PLATELET RICH PLASMA; CAPILLARY; CELL PROLIFERATION; CLINICAL ARTICLE; CLINICAL EVALUATION; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; EPIDERMIS; EPILUMINESCENCE MICROSCOPY; HAIR FOLLICLE; HAIR GROWTH; HAIR LOSS; HAIR TEXTURE; HUMAN; HUMAN TISSUE; KERATINOCYTE; MALE; MORPHOMETRICS; PATTERN HAIR LOSS; PRURITUS; PUNCH BIOPSY; RANDOMIZED CONTROLLED TRIAL; SKIN SENSATION; THERAPY EFFECT; THROMBOCYTE ACTIVATION; THROMBOCYTE RICH PLASMA; ALOPECIA; CHEMISTRY; DRUG EFFECTS; GROWTH, DEVELOPMENT AND AGING; INJECTION; MIDDLE AGED; PATHOLOGY; SCALP;

ADULT; ALOPECIA; CELL PROLIFERATION; EPIDERMIS; HAIR FOLLICLE; HUMANS; INJECTIONS; KERATINOCYTES; MALE; MIDDLE AGED; PLATELET-RICH PLASMA; SCALP;

EID: 84901773748     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2014/760709     Document Type: Article

References (26)

1. Takikawa M., Nakamura S., Nakamura S., Ishirara M., Kishimoto S., Sasaki K., Yanagibayashi S., Azuma R., Yamamoto N., Kiyosawa T., Enhanced effect of platelet-rich plasma containing a new carrier on hair growth. Dermatologic Surgery 2011 37 12 1721 1729 2-s2.0-80051545594 10.1111/j.1524-4725.2011.02123.x
2. Li Z. J., Choi H.-I., Choi D.-K., Autologous platelet-rich plasma: a potential therapeutic tool for promoting hair growth. Dermatologic Surgery 2012 38 7, part 11 1040 1046 10.1111/j.1524-4725.2012.02394.x
3. Uebel C. O., da Silva J. B., Cantarelli D., Martins P., The role of platelet plasma growth factors in male pattern baldness surgery. Plastic and Reconstructive Surgery 2006 118 6 1458 1466 2-s2.0-33750238651 10.1097/01.prs.0000239560.29172.33 (Pubitemid 44610398)
4. Trink A., Sorbellini E., Bezzola P., Rodella L., Rezzani R., Ramot Y., Rinaldi F., A randomized, double-blind, placebo- and active-controlled, half-head study to evaluate the effects of platelet-rich plasma on alopecia areata. British Journal of Dermatology 2013 169 3 690 694 10.1111/bjd.12397
5. Mecklenburg L., Tobin D. J., Müller-Röver S., Active hair growth (anagen) is associated with angiogenesis. Journal of Investigative Dermatology 2000 114 5 909 916 10.1046/j.1523-1747.2000.00954.x (Pubitemid 30252710)
6. Lachgar S., Moukadiri H., Jonca F., Vascular endothelial growth factor is an autocrine growth factor for hair dermal papilla cells. Journal of Investigative Dermatology 1996 106 1 17 23 2-s2.0-0030065658 (Pubitemid 26052046)
7. Kozlowska U., Blume-Peytavi U., Kodelja V., Sommer C., Goerdt S., Majewski S., Jablonska S., Orfanos C. E., Expression of vascular endothelial growth factor (VEGF) in various compartments of the human hair follicle. Archives of Dermatological Research 1998 290 12 661 668 2-s2.0-0032414248 10.1007/s004030050370 (Pubitemid 29004760)
8. Tarallo V., Vesci L., Capasso O., Esposito M. T., Riccioni T., Pastore L., Orlandi A., Pisano C., de Falco S., A placental growth factor variant unable to recognize Vascular Endothelial Growth Factor (VEGF) receptor-1 inhibits VEGF-dependent tumor angiogenesis via heterodimerization. Cancer Research 2010 70 5 1804 1813 2-s2.0-77950202451 10.1158/0008-5472.CAN-09-2609
9. Tobin D. J., Gunin A., Magerl M., Handijski B., Paus R., Plasticity and cytokinetic dynamics of the hair follicle mesenchyme: implications for hair growth control. Journal of Investigative Dermatology 2003 120 6 895 904 2-s2.0-0038468638 10.1046/j.1523-1747.2003.12237.x (Pubitemid 36702896)
10. Li W., Enomoto M., Ukegawa M., Hirai T., Sotome S., Wakabayashi Y., Shinomiya K., Okawa A., Subcutaneous injections of platelet-rich plasma into skin flaps modulate proangiogenic gene expression and improve survival rates. Plastic and Reconstructive Surgery 2012 129 4 858 866 2-s2.0-84859316966 10.1097/PRS.0b013e3182450ac9
11. Semalty M., Semalty A., Joshi G. P., Rawat M. S. M., Hair growth and rejuvenation: an overview. Journal of Dermatological Treatment 2011 22 3 123 132 2-s2.0-79952219279 10.3109/09546630903578574
12. Cervelli V., Scioli M. G., Gentile P., Doldo E., Bonanno E., Spagnoli L. G., Orlandi A., Platelet-rich plasma greatly potentiates insulin-induced adipogenic differentiation of human adipose-derived stem cells through a serine/threonine kinase Akt-dependent mechanism and promotes clinical fat graft maintenance. Stem Cells Translational Medicine 2012 1 3 206 220 10.5966/sctm.2011-0052
13. Cervelli V., Gentile P., Scioli M. G., Grimaldi M., Casciani C. U., Spagnoli L. G., Orlandi A., Application of platelet-rich plasma in plastic surgery: clinical and in vitro evaluation. Tissue Engineering C: Methods 2009 15 4 625 634 2-s2.0-72249117769 10.1089/ten.tec.2008.0518
14. Cervelli V., Gentile P., de Angelis B., Calabrese C., di Stefani A., Scioli M. G., Curcio B. C., Felici M., Orlandi A., Application of enhanced stromal vascular fraction and fat grafting mixed with PRP in post-traumatic lower extremity ulcers. Stem Cell Research 2011 6 2 103 111 2-s2.0-79951512660 10.1016/j.scr.2010.11.003
15. Campagnolo L., Costanza G., Francesconi A., Arcuri G., Moscatelli I., Orlandi A., Sortilin expression is essential for pro-nerve growth factor-induced apoptosis of rat vascular smooth muscle cells. PLoS ONE 2014 9 1 e84969 10.1371/journal.pone.0084969
16. Francesconi A., Arcuri G., Doldo E., Scioli M. G., de Falco S., Spagnoli L. G., Orlandi A., Age-related increase of stem marker expression influences vascular smooth muscle cell properties. Atherosclerosis 2012 224 1 51 57
17. Stasi M. A., Scioli M. G., Arcuri G., Mattera G. G., Lombardo K., Marcellini M., Riccioni T., de Falco S., Pisano C., Spagnoli L. G., Borsini F., Orlandi A., Propionyl- l -carnitine improves postischemic blood flow recovery and arteriogenetic revascularization and reduces endothelial NADPH-oxidase 4-mediated superoxide production. Arteriosclerosis, Thrombosis, and Vascular Biology 2010 30 3 426 435 2-s2.0-77649148275 10.1161/ATVBAHA.109.201533
18. Han J. H., Kwon O. S., Chung J. H., Cho K. H., Eun H. C., Kim K. H., Effect of minoxidil on proliferation and apoptosis in dermal papilla cells of human hair follicle. Journal of Dermatological Science 2004 34 2 91 98 2-s2.0-1642360019 10.1016/j.jdermsci.2004.01.002 (Pubitemid 38368947)
19. Tosti A., Piraccini B. M., Finasteride and the hair cycle. Journal of the American Academy of Dermatology 2000 42 5 848 849 2-s2.0-0034025306
20. Sawaya M. E., Blume-Peytavi U., Mullins D. L., Nusbaum B. P., Whiting D., Nicholson D. W., Lotocki G., Keane R. W., Effects of finasteride on apoptosis and regulation of the human hair cycle. Journal of Cutaneous Medicine and Surgery 2002 6 1 1 9 2-s2.0-0036209791 10.1007/s10227-001-0024-y (Pubitemid 34279786)
21. Vaccari J. P. D. R., Sawaya M. E., Brand F. III, Nusbaum B. P., Bauman A. J., Bramlett H. M., Dietrich W. D., Keane R. W., Caspase-1 level is higher in the scalp in androgenetic alopecia. Dermatologic Surgery 2012 38 7, part 11 1033 1039 2-s2.0-84857937003 10.1111/j.1524-4725.2012.02378.x
22. Ferraris C., Cooklis M., Polakowska R. R., Haake A. R., Induction of apoptosis through the PKC pathway in cultured dermal papilla fibroblasts. Experimental Cell Research 1997 234 1 37 46 2-s2.0-0031563140 10.1006/excr.1997.3601 (Pubitemid 27317900)
23. Kwon O. S., Pyo H. K., Oh Y. J., Promotive effect of minoxidil combined with all- trans retinoic acid (tretinoin) on human hair growth in vitro. Journal of Korean Medical Science 2007 22 2 283 289 2-s2.0-34248513497
24. Sohn K.-C., Shi G., Jang S., Choi D.-K., Lee Y., Yoon T.-J., Park H., Hwang C., Kim H. J., Seo Y.-J., Lee J.-H., Park J.-K., Kim C. D., Pitx2, a β -catenin-regulated transcription factor, regulates the differentiation of outer root sheath cells cultured in vitro. Journal of Dermatological Science 2009 54 1 6 11 2-s2.0-60749098058 10.1016/j.jdermsci.2008.11.006
25. Kang J.-S., Zheng Z., Choi M. J., Lee S.-H., Kim D.-Y., Cho S. B., The effect of CD34+ cell-containing autologous platelet-rich plasma injection on pattern hair loss: a preliminary study. Journal of the European Academy of Dermatology and Venereology 2014 28 1 72 79 10.1111/jdv.12062
26. Giusti I., Rughetti A., D'Ascenzo S., Identification of an optimal concentration of platelet gel for promoting angiogenesis in human endothelial cells. Transfusion 2009 49 4 771 778 2-s2.0-62949099625 10.1111/j.1537-2995. 2008.02033.x