JMJD2A predicts prognosis and regulates cell growth in human gastric cancer

Biochemical and Biophysical Research Communications

Volumn 449, Issue 1, 2014, Pages 1-7

  Hu, Cheng En ^a   Liu, Yong Chao ^a   Zhang, Hui Dong ^b   Huang, Guang Jian ^a  

^a FUDAN UNIVERSITY   (China)

^b SHANGHAI CHILDREN S MEDICAL CENTER   (China)

Author keywords

Apoptosis; Gastric cancer; JMJD2A; miR 34a; Prognosis

Indexed keywords

HISTONE DEMETHYLASE; HISTONE H3; JMJD2A PROTEIN; MICRORNA 34A; RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CELL; CANCER PROGNOSIS; CELL GROWTH; CELL PROLIFERATION ASSAY; CONTROLLED STUDY; ENZYME ACTIVITY; GROWTH REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUCIFERASE ASSAY; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; STOMACH CANCER; STOMACH MUCOSA; TRANSCRIPTION REGULATION; TUMOR XENOGRAFT; WESTERN BLOTTING;

MAMMALIA;

APOPTOSIS; GASTRIC CANCER; JMJD2A; MIR-34A; PROGNOSIS;

AGED; AGED, 80 AND OVER; ANIMALS; CELL PROLIFERATION; CHINA; DISEASE-FREE SURVIVAL; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; JUMONJI DOMAIN-CONTAINING HISTONE DEMETHYLASES; LYMPHATIC METASTASIS; MALE; MICE; MIDDLE AGED; NEOPLASM STAGING; PREVALENCE; PROGNOSIS; RISK ASSESSMENT; STOMACH NEOPLASMS; SURVIVAL RATE; TUMOR BURDEN; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL;

EID: 84901756565     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.04.126     Document Type: Article

References (25)

1. W.L. Berry, and R. Janknecht KDM4/JMJD2 histone demethylases: epigenetic regulators in cancer cells Cancer Res. 73 2013 2936 2942
2. J.C. Black, C. Van Rechem, and J.R. Whetstine Histone lysine methylation dynamics: establishment, regulation, and biological impact Mol. Cell 48 2012 491 507
3. D. Zhang, H.G. Yoon, and J. Wong JMJD2A is a novel N-CoR-interacting protein and is involved in repression of the human transcription factor achaete scute-like homologue 2 (ASCL2/Hash2) Mol. Cell. Biol. 25 2005 6404 6414 (Pubitemid 41023217)
4. S.G. Gray, A.H. Iglesias, F. Lizcano, R. Villanueva, S. Camelo, H. Jingu, B.T. Teh, N. Koibuchi, W.W. Chin, E. Kokkotou, and F. Dangond Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein J. Biol. Chem. 280 2005 28507 28518 (Pubitemid 41105751)
5. T.D. Kim, S. Shin, W.L. Berry, S. Oh, and R. Janknecht The JMJD2A demethylase regulates apoptosis and proliferation in colon cancer cells J. Cell. Biochem. 113 2012 1368 1376
6. S. Shin, and R. Janknecht Activation of androgen receptor by histone demethylases JMJD2A and JMJD2D Biochem. Biophys. Res. Commun. 359 2007 742 746 (Pubitemid 46901127)
7. W.L. Berry, S. Shin, S.A. Lightfoot, and R. Janknecht Oncogenic features of the JMJD2A histone demethylase in breast cancer Int. J. Oncol. 41 2012 1701 1706
8. M.D. Taylor, S. Sadhukhan, P. Kottangada, A. Ramgopal, K. Sarkar, S. D'Silva, A. Selvakumar, F. Candotti, and Y.M. Vyas Nuclear role of WASp in the pathogenesis of dysregulated TH1 immunity in human Wiskott-Aldrich syndrome Sci. Transl. Med. 2 2010 37ra44
9. P.C. Chang, L.D. Fitzgerald, D.A. Hsia, Y. Izumiya, C.Y. Wu, W.P. Hsieh, S.F. Lin, M. Campbell, K.S. Lam, P.A. Luciw, C.G. Tepper, and H.J. Kung Histone demethylase JMJD2A regulates Kaposi's sarcoma-associated herpesvirus replication and is targeted by a viral transcriptional factor J. Virol. 85 2011 3283 3293
10. Q.J. Zhang, H.Z. Chen, L. Wang, D.P. Liu, J.A. Hill, and Z.P. Liu The histone trimethyllysine demethylase JMJD2A promotes cardiac hypertrophy in response to hypertrophic stimuli in mice J. Clin. Invest. 121 2011 2447 2456
11. F.A. Mallette, F. Mattiroli, G. Cui, L.C. Young, M.J. Hendzel, G. Mer, T.K. Sixma, and S. Richard RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites EMBO J. 31 2012 1865 1878
12. B.X. Li, J. Li, C.L. Luo, M.C. Zhang, H. Li, L.L. Li, H.F. Xu, Y.W. Shen, A.M. Xue, and Z.Q. Zhao Expression of JMJD2A in infiltrating duct carcinoma was markedly higher than fibroadenoma, and associated with expression of ARHI, p53 and ER in infiltrating duct carcinoma Indian J. Exp. Biol. 51 2013 208 217
13. B.X. Li, M.C. Zhang, C.L. Luo, P. Yang, H. Li, H.M. Xu, H.F. Xu, Y.W. Shen, A.M. Xue, and Z.Q. Zhao Effects of RNA interference-mediated gene silencing of JMJD2A on human breast cancer cell line MDA-MB-231 in vitro J. Exp. Clin. Cancer Res. 30 2011 90
14. M. Kogure, M. Takawa, H.S. Cho, G. Toyokawa, K. Hayashi, T. Tsunoda, T. Kobayashi, Y. Daigo, M. Sugiyama, Y. Atomi, Y. Nakamura, and R. Hamamoto Deregulation of the histone demethylase JMJD2A is involved in human carcinogenesis through regulation of the G(1)/S transition Cancer Lett. 336 2013 76 84
15. F.A. Mallette, and S. Richard JMJD2A promotes cellular transformation by blocking cellular senescence through transcriptional repression of the tumor suppressor CHD5 Cell Rep. 2 2012 1233 1243
16. E.C. Kauffman, B.D. Robinson, M.J. Downes, L.G. Powell, M.M. Lee, D.S. Scherr, L.J. Gudas, and N.P. Mongan Role of androgen receptor and associated lysine-demethylase coregulators, LSD1 and JMJD2A, in localized and advanced human bladder cancer Mol. Carcinog. 50 2011 931 944
17. Joshua C. Black, Amity L. Manning, C. Van Rechem, J. Kim, B. Ladd, J. Cho, Cristiana M. Pineda, N. Murphy, Danette L. Daniels, C. Montagna, Peter W. Lewis, K. Glass, C.D. Allis, Nicholas J. Dyson, G. Getz, and Johnathan R. Whetstine KDM4A lysine demethylase induces site-specific copy gain and rereplication of regions amplified in tumors Cell 154 2013 541 555
18. S.R. Hamilton, and L.A. Aaltonen Pathology and Genetics of Tumours of the Digestive System 2000 IARC Press Lyon
19. T.-C. Chang, E.A. Wentzel, O.A. Kent, K. Ramachandran, M. Mullendore, Kwang H. Lee, G. Feldmann, M. Yamakuchi, M. Ferlito, C.J. Lowenstein, Dan E. Arking, M.A. Beer, A. Maitra, and J.T. Mendell Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis Mol. Cell 26 2007 745 752 (Pubitemid 46856245)
20. L. Ding, Y. Xu, W. Zhang, Y. Deng, M. Si, Y. Du, H. Yao, X. Liu, Y. Ke, J. Si, and T. Zhou MiR-375 frequently downregulated in gastric cancer inhibits cell proliferation by targeting JAK2 Cell Res. 20 2010 784 793
21. S. Osawa, Y. Shimada, S. Sekine, T. Okumura, T. Nagata, J. Fukuoka, and K. Tsukada MicroRNA profiling of gastric cancer patients from formalin-fixed paraffin-embedded samples Oncol. Lett. 2 2011 613 619
22. É. Stánitz, K. Juhász, C. Tóth, K. Gombos, P.G. Natali, and I. Ember Evaluation of MicroRNA expression pattern of gastric adenocarcinoma associated with socioeconomic, environmental and lifestyle factors in Northwestern hungary Anticancer Res. 33 2013 3195 3200
23. W. Cao, R. Fan, L. Wang, S. Cheng, H. Li, J. Jiang, M. Geng, Y. Jin, and Y. Wu Expression and regulatory function of miRNA-34a in targeting survivin in gastric cancer cells Tumor Biol. 34 2013 963 971
24. M.V. Botuyan, J. Lee, I.M. Ward, J.E. Kim, J.R. Thompson, J. Chen, and G. Mer Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair Cell 127 2006 1361 1373 (Pubitemid 44960409)
25. T.C. Chang, E.A. Wentzel, O.A. Kent, K. Ramachandran, M. Mullendore, K.H. Lee, G. Feldmann, M. Yamakuchi, M. Ferlito, C.J. Lowenstein, D.E. Arking, M.A. Beer, A. Maitra, and J.T. Mendell Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis Mol. Cell 26 2007 745 752 (Pubitemid 46856245)