A randomized clinical trial to determine optimal infertility treatment in older couples: The Forty and over Treatment Trial (FORT-T)

Fertility and Sterility

Volumn 101, Issue 6, 2014, Pages

  Goldman, Marlene B ^a,b   Thornton, Kim L ^c   Ryley, David ^c   Alper, Michael M ^c   Fung, June L ^a   Hornstein, Mark D ^d   Reindollar, Richard H ^a,e  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

^c BOSTON IVF   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e AMERICAN SOCIETY FOR REPRODUCTIVE MEDICINE   (United States)

Author keywords

Advanced reproductive age; clomiphene citrate; controlled ovarian hyperstimulation; follicle stimulating hormone; FORT T Trial; in vitro fertilization; intrauterine insemination (IUI); unexplained infertility

Indexed keywords

CLOMIFENE CITRATE; FOLLITROPIN;

ADULT; ADVERSE OUTCOME; ARTICLE; CONCEPTION; FEMALE; FEMALE INFERTILITY; FERTILIZATION IN VITRO; FOLLOW UP; HUMAN; INFERTILITY THERAPY; INSURANCE; INTRAUTERINE INSEMINATION; LIVE BIRTH; MAJOR CLINICAL STUDY; MULTIPLE CYCLE TREATMENT; MULTIPLE PREGNANCY; PREGNANCY RATE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); TIME TO PREGNANCY;

ADVANCED REPRODUCTIVE AGE; CLOMIPHENE CITRATE; CONTROLLED OVARIAN HYPERSTIMULATION; FOLLICLE-STIMULATING HORMONE; FORT-T TRIAL; INTRAUTERINE INSEMINATION (IUI); IN VITRO FERTILIZATION; UNEXPLAINED INFERTILITY;

ADULT; AGE FACTORS; BOSTON; CLOMIPHENE; COMBINED MODALITY THERAPY; DRUG ADMINISTRATION SCHEDULE; FEMALE; FERTILITY; FERTILITY AGENTS, FEMALE; FERTILIZATION IN VITRO; FOLLICLE STIMULATING HORMONE; HUMANS; INFERTILITY, FEMALE; INFERTILITY, MALE; INSEMINATION, ARTIFICIAL; LIVE BIRTH; MALE; MIDDLE AGED; PATIENT SELECTION; PREGNANCY; PREGNANCY RATE; REPRODUCTIVE TECHNIQUES, ASSISTED; RISK FACTORS; TIME FACTORS; TIME-TO-PREGNANCY; TREATMENT OUTCOME;

EID: 84901744798     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2014.03.012     Document Type: Article

References (10)

1. D.S. Guzick, M.W. Sullivan, G.D. Adamson, M.I. Cedars, R.J. Falk, and E.P. Peterson et al. Efficacy of treatment for unexplained infertility Fertil Steril 70 1998 207 213 (Pubitemid 28361468)
2. D.S. Guzick, S.A. Carson, C. Coutifaris, J.W. Overstreet, P. Factor-Litvak, and M.P. Steinkampf et al. Efficacy of superovulation and intrauterine insemination in the treatment of infertility N Engl J Med 340 1999 177 183 (Pubitemid 29063213)
3. R.H. Reindollar, and M.B. Goldman Gonadotropin therapy: a 20th century relic Fertil Steril 97 2012 813 818
4. H.D. McClamrock, H.W. Jones, and E.Y. Adashi Ovarian stimulation and intrauterine insemination at the quarter centennial: implications for the multiple births epidemic Fertil Steril 97 2012 802 809
5. R.H. Reindollar, M.M. Regan, P.J. Neumann, B. Levine, K.L. Thornton, and M.M. Alper et al. A randomized clinical trial to evaluate optimal treatment for unexplained infertility: the fast track and standard treatment (FASTT) trial Fertil Steril 94 2010 888 899
6. The Practice Committees of the American Society for Reproductive Medicine and the Society for Assisted Reproductive Technology Criteria for number of embryos to transfer: a committee opinion Fertil Steril 99 2013 44 46
7. I.M. Custers, M.M.E. van Rumste, J.W. van der Steeg, M. van Wely, P.G.A. Hompes, and P. Bossuyt et al. Long-term outcome of couples with unexplained subfertility and an intermediate prognosis initially randomized between expectant management and immediate treatment Hum Reprod 27 2012 444 450
8. R.P. Dickey, S.N. Taylor, P.Y. Lu, B.M. Sartor, P.H. Rye, and R. Pyrzak Relationship of follicle numbers and estradiol levels to multiple implantation in 3,608 intrauterine insemination cycles Fertil Steril 75 2001 69 78 (Pubitemid 32043596)
9. N. Gleicher, D.M. Oleske, I. Tur-Kaspa, A. Vidali, and V. Karande Reducing the risk of high-order multiple pregnancy after ovarian stimulation with gonadotropins N Engl J Med 343 2000 2 7 (Pubitemid 30447985)
10. P. Katz, J. Showstack, J.F. Smith, R.D. Natchtigall, S.G. Millstein, and H. Wing et al. Costs of infertility treatment: results from an 18-month prospective cohort study Fertil Steril 95 2011 915 921