Glucose hypometabolism is highly localized, but lower cortical thickness and brain atrophy are widespread in cognitively normal older adults

American Journal of Physiology - Endocrinology and Metabolism

Volumn 306, Issue 11, 2014, Pages

  Nugent, Scott ^a   Castellano, Christian Alexandre ^a   Goffaux, Philippe ^c   Whittingstall, Kevin ^a,b   Lepage, Martin ^a,b   Paquet, Nancy ^a   Bocti, Christian ^a   Fulop, Tamas ^a   Cunnane, Stephen C ^a  

^a UNIVERSITÉ DE SHERBROOKE   (Canada)

^b UNIVERSITY OF SHERBROOKE   (Canada)

^c CENTRE HOSPITALIER UNIVERSITAIRE DE SHERBROOKE   (Canada)

Author keywords

Aging; Cerebral glucose metabolism; Cortical thickness; Cortical volume; Positron emission tomography

Indexed keywords

IRBESARTAN; RAMIPRIL; TELMISARTAN;

ADULT; AGED; AGING; ARTICLE; BRAIN ATROPHY; BRAIN REGION; COGNITION; CONTROLLED STUDY; CORTICAL THICKNESS (BRAIN); FEMALE; FRONTAL CORTEX; GLUCOSE BRAIN LEVEL; GLUCOSE METABOLISM; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; METABOLIC RATE; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL;

AGING; CEREBRAL GLUCOSE METABOLISM; CORTICAL THICKNESS; CORTICAL VOLUME; POSITRON EMISSION TOMOGRAPHY;

ADULT; AGED; AGING; ANTIHYPERTENSIVE AGENTS; ATROPHY; BLOOD GLUCOSE; BRAIN; BRAIN CHEMISTRY; CEREBRAL CORTEX; COGNITION; EXECUTIVE FUNCTION; FEMALE; FLUORODEOXYGLUCOSE F18; GLUCOSE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; KINETICS; MAGNETIC RESONANCE IMAGING; MALE; MEMORY, LONG-TERM; MEMORY, SHORT-TERM; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; YOUNG ADULT;

EID: 84901725111     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00067.2014     Document Type: Article

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