Clinically inactive disease in a cohort of children with new-onset polyarticular juvenile idiopathic arthritis treated with early aggressive therapy: Time to achievement, total duration, and predictors

Journal of Rheumatology

Volumn 41, Issue 6, 2014, Pages 1163-1170

  Wallace, Carol A ^a   Giannini, Edward H ^b   Spalding, Steven J ^c   Hashkes, Philip J ^d   O'Neil, Kathleen M ^e   Zeft, Andrew S ^c   Szer, Ilona S ^f   Ringold, Sarah ^a   Brunner, Hermine I ^b   Schanberg, Laura E ^g   Sundel, Robert P ^h   Milojevic, Diana S ⁱ   Punaro, Marilynn G ^j   Chira, Peter ^e   Gottlieb, Beth S ^k   Higgins, Gloria C ^l   Ilowite, Norman T ^m   Kimura, Yukiko ⁿ   Johnson, Anne ^o   Huang, Bin ^o   Lovell, Daniel J ^b   more..

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c LERNER RESEARCH INSTITUTE   (United States)

^d SHAARE ZEDEK MEDICAL CENTER   (Israel)

^e INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f RADY CHILDREN'S HOSPITAL   (United States)

^g DUKE UNIVERSITY MEDICAL CENTER   (United States)

^h BOSTON CHILDREN S HOSPITAL   (United States)

ⁱ TUFTS MEDICAL CENTER   (United States)

^j TEXAS SCOTTISH RITE HOSPITAL FOR CHILDREN   (United States)

^k DONALD AND BARBARA ZUCKER SCHOOL OF MEDICINE AT HOFSTRA NORTHWELL   (United States)

^l OHIO STATE UNIVERSITY   (United States)

^m CHILDREN S HOSPITAL AT MONTEFIORE   (United States)

ⁿ HACKENSACK UNIVERSITY MEDICAL CENTER   (United States)

^o CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

more..

Author keywords

Children 2 16 years; Clinical trial; Clinically inactive disease; Early aggressive therapy; Juvenile idiopathic arthritis

Indexed keywords

ETANERCEPT; METHOTREXATE; PREDNISOLONE; ANTIRHEUMATIC AGENT; IMMUNOGLOBULIN G; TNFR-FC FUSION PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR;

ADOLESCENT; ARTICLE; CHILD; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE COURSE; DISEASE DURATION; DISEASE EXACERBATION; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG DOSE REDUCTION; FEMALE; FOLLOW UP; HUMAN; JUVENILE RHEUMATOID ARTHRITIS; MAJOR CLINICAL STUDY; MALE; MONOTHERAPY; PREDICTION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT DURATION; ARTHRITIS, JUVENILE; DRUG COMBINATION; PRESCHOOL CHILD; REMISSION; TREATMENT OUTCOME;

ADOLESCENT; ANTIRHEUMATIC AGENTS; ARTHRITIS, JUVENILE; CHILD; CHILD, PRESCHOOL; DISEASE PROGRESSION; DOUBLE-BLIND METHOD; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; IMMUNOGLOBULIN G; MALE; METHOTREXATE; PREDNISOLONE; RECEPTORS, TUMOR NECROSIS FACTOR; REMISSION INDUCTION; TREATMENT OUTCOME;

EID: 84901717762     PISSN: 0315162X     EISSN: 14992752     Source Type: Journal    
DOI: 10.3899/jrheum.131503     Document Type: Article

References (11)

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2. Lovell DJ, Ruperto N, Goodman S, Reiff A, Jung L, Jarosova K, et al. Adalimumab with or without methotrexate in juvenile rheumatoid arthritis. N Engl J Med 2008;359:810-20.
3. Lovell DJ, Reiff A, Ilowite NT, Wallace CA, Chon Y, Lin SL, et al. Safety and efficacy of up to eight years of continuous etanercept therapy in patients with juvenile rheumatoid arthritis. Arthritis Rheum 2008;58:1496-504. (Pubitemid 351705939)
4. Ruperto N, Lovell DJ, Quartier P, Paz E, Rubio-Perez N, Silva CA, et al. Abatacept in children with juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled withdrawal trial. Lancet 2008;372:383-91.
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10. Wallace CA, Giannini EH, Spalding S, Hashkes P, O'Neil K, Zeft A, et al. Trial of early aggressive therapy in polyarticular juvenile idiopathic arthritis. Arthritis Rheum 2012;64:2012-21.
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