Trial of early aggressive therapy in polyarticular juvenile idiopathic arthritis

Arthritis and Rheumatism

Volumn 64, Issue 6, 2012, Pages 2012-2021

  Wallace, Carol A ^a   Giannini, Edward H ^b   Spalding, Steven J ^c,p   Hashkes, Philip J ^c,p   O'Neil, Kathleen M ^d   Zeft, Andrew S ^c,e   Szer, Ilona S ^f   Ringold, Sarah ^a   Brunner, Hermine I ^b   Schanberg, Laura E ^g   Sundel, Robert P ^h   Milojevic, Diana ⁱ   Punaro, Marilynn G ^j   Chira, Peter ^k,q   Gottlieb, Beth S ^l   Higgins, Gloria C ^m   Ilowite, Norman T ⁿ   Kimura, Yukiko ^o   Hamilton, Stephanie ^a   Johnson, Anne ^b   Huang, Bin ^b   Lovell, Daniel J ^b   more..

^a SEATTLE CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c LERNER RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^e UNIVERSITY OF UTAH   (United States)

^f RADY CHILDREN'S HOSPITAL   (United States)

^g DUKE UNIVERSITY MEDICAL CENTER   (United States)

^h BOSTON CHILDREN S HOSPITAL   (United States)

ⁱ UNIVERSITY OF CALIFORNIA   (United States)

^j Texas Scottish Rite Hospital   (United States)

^k STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^l Hofstra Northwell Steven and Alexandra Cohen Children s Medical Center of NY Northwell Health   (United States)

^m OHIO STATE UNIVERSITY   (United States)

ⁿ ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^o HACKENSACK UNIVERSITY MEDICAL CENTER   (United States)

^p SHAARE ZEDEK MEDICAL CENTER   (Israel)

^q INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ETANERCEPT; METHOTREXATE; PREDNISOLONE; RHEUMATOID FACTOR;

ADJUSTMENT DISORDER; ADOLESCENT; AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; CHILD; CONTROLLED STUDY; COXITIS; DISEASE DURATION; DISEASE EXACERBATION; DOUBLE BLIND PROCEDURE; DRUG SAFETY; DRUG WITHDRAWAL; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; HERPES SIMPLEX; HUMAN; JUVENILE RHEUMATOID ARTHRITIS; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; MONOTHERAPY; MULTICENTER STUDY; PERITONSILLAR ABSCESS; PNEUMONIA; PRESCHOOL CHILD; PRIORITY JOURNAL; PROSPECTIVE STUDY; PSYCHOSIS; RANDOMIZED CONTROLLED TRIAL; REMISSION; SCHOOL CHILD; SEPSIS; SIDE EFFECT;

ADOLESCENT; ANTIRHEUMATIC AGENTS; ARTHRITIS, JUVENILE RHEUMATOID; CHILD; CHILD, PRESCHOOL; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; IMMUNOGLOBULIN G; LONGITUDINAL STUDIES; MALE; METHOTREXATE; PREDNISOLONE; PROSPECTIVE STUDIES; RECEPTORS, TUMOR NECROSIS FACTOR; REMISSION INDUCTION; TREATMENT OUTCOME;

EID: 84861815507     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.34343     Document Type: Article

References (32)

1. Petty RE, Southwood TR, Manners P, Baum J, Glass DN, Goldenberg J, et al. International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: second revision, Edmonton, 2001. J Rheumatol 2004; 31: 390-2.
2. Gortmaker SL, Sappenfield W,. Chronic childhood disorders: prevalence and impact. Pediatr Clin North Am 1984; 31: 3-18.
3. Singsen BH,. Rheumatic disease of childhood. Rheum Dis Clin North Am 1990; 16: 581-99.
4. Lovell DJ, Giannini EH, Reiff A, Cawkwell GD, Silverman ED, Nocton JJ, et al, for the Pediatric Rheumatology Collaborative Study Group. Etanercept in children with polyarticular juvenile rheumatoid arthritis. N Engl J Med 2000; 342: 763-9.
5. Lovell DJ, Ruperto N, Goodman S, Reiff A, Jung L, Jarosova K, et al. Adalimumab with or without methotrexate in juvenile rheumatoid arthritis. N Engl J Med 2008; 359: 810-20.
6. Foell D, Wulffraat N, Wedderburn LR, Wittkowski H, Frosch M, Gerss J, et al, and the Paediatric Rheumatology International Trials Organization (PRINTO). Methotrexate withdrawal at 6 vs 12 months in juvenile idiopathic arthritis in remission: a randomized clinical trial. JAMA 2010; 303: 1266-73.
7. Lovell DJ, Reiff A, Ilowite NT, Wallace CA, Chon Y, Lin SL, et al, for the Pediatric Rheumatology Collaborative Study Group. Safety and efficacy of up to eight years of continuous etanercept therapy in patients with juvenile rheumatoid arthritis. Arthritis Rheum 2008; 58: 1496-504.
8. Ruperto N, Lovell DJ, Quartier P, Paz E, Rubio-Perez N, Silva CA, et al. Abatacept in children with juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled withdrawal trial. Lancet 2008; 372: 383-91.
9. Beukelman T, Patkar NM, Saag KG, Tolleson-Rinehart S, Cron RQ, DeWitt EM, et al. 2011 American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: initiation and safety monitoring of therapeutic agents for the treatment of arthritis and systemic features. Arthritis Care Res (Hoboken) 2011; 63: 465-82.
10. Saxena N, Aggarwal A, Misra R,. Elevated concentrations of monocyte derived cytokines in synovial fluid of children with enthesitis related arthritis and polyarticular types of juvenile idiopathic arthritis. J Rheumatol 2005; 32: 1349-53.
11. Black AP, Bhayani H, Ryder CA, Pugh MT, Gardner-Medwin JM, Southwood TR,. An association between the acute phase response and patterns of antigen induced T cell proliferation in juvenile idiopathic arthritis. Arthritis Res Ther 2003; 5: R277-84.
12. Albers HM, Brinkman DM, Kamphuis SS, van Suijlekom-Smit LW, van Rossum MA, Hoppenreijs EP, et al. Clinical course and prognostic value of disease activity in the first two years in different subtypes of juvenile idiopathic arthritis. Arthritis Care Res (Hoboken) 2010; 62: 204-12.
13. Shenoi S, Wallace CA,. Remission in juvenile idiopathic arthritis: current facts. Curr Rheumatol Rep 2010; 12: 80-6.
14. Wallace CA, Huang B, Bandeira M, Ravelli A, Giannini EH,. Patterns of clinical remission in select categories of juvenile idiopathic arthritis. Arthritis Rheum 2005; 52: 3554-62.
15. Anderson JJ, Wells G, Verhoeven AC, Felson DT,. Factors predicting response to treatment in rheumatoid arthritis: the importance of disease duration. Arthritis Rheum 2000; 43: 22-9.
16. Moreland LW, Bridges SL Jr., Early rheumatoid arthritis: a medical emergency? Am J Med 2001; 111: 498-500.
17. Mottonen T, Hannonen P, Korpela M, Nissila M, Kautiainen H, Ilonen J, et al. Delay to institution of therapy and induction of remission using single-drug or combination-disease-modifying antirheumatic drug therapy in early rheumatoid arthritis. Arthritis Rheum 2002; 46: 894-8.
18. Boers M,. Understanding the window of opportunity concept in early rheumatoid arthritis [editorial]. Arthritis Rheum 2003; 48: 1771-4.
19. O'Dell JR,. Treating rheumatoid arthritis early: a window of opportunity? [editorial]. Arthritis Rheum 2002; 46: 283-5.
20. Quinn MA, Emery P,. Window of opportunity in early rheumatoid arthritis: possibility of altering the disease process with early intervention. Clin Exp Rheumatol 2003; 21: S154-7.
21. Wallace CA, Ruperto N, Giannini E,. Preliminary criteria for clinical remission for select categories of juvenile idiopathic arthritis. J Rheumatol 2004; 31: 2290-4.
22. Singh G, Athreya BH, Fries JF, Goldsmith DP,. Measurement of health status in children with juvenile rheumatoid arthritis. Arthritis Rheum 1994; 37: 1761-9.
23. National Cancer Institute. Common terminology criteria for adverse events (CTCAE): glossary report. Version 3. Bethesda (MD): NIH, National Cancer Institute; 2003.
24. Giannini EH, Ruperto N, Ravelli A, Lovell DJ, Felson DT, Martini A,. Preliminary definition of improvement in juvenile arthritis. Arthritis Rheum 1997; 40: 1202-9.
25. Bowyer SL, Roettcher PA, Higgins GC, Adams B, Myers LK, Wallace C, et al. Health status of patients with juvenile rheumatoid arthritis at 1 and 5 years after diagnosis. J Rheumatol 2003; 30: 394-400.
26. Magni-Manzoni S, Rossi F, Pistorio A, Temporini F, Viola S, Beluffi G, et al. Prognostic factors for radiographic progression, radiographic damage, and disability in juvenile idiopathic arthritis. Arthritis Rheum 2003; 48: 3509-17.
27. Mason T, Reed AM, Nelson AM, Thomas KB,. Radiographic progression in children with polyarticular juvenile rheumatoid arthritis: a pilot study. Ann Rheum Dis 2005; 64: 491-3.
28. Zak M, Hassager C, Lovell DJ, Nielsen S, Henderson CJ, Pedersen FK,. Assessment of bone mineral density in adults with a history of juvenile chronic arthritis: a cross-sectional long-term followup study. Arthritis Rheum 1999; 42: 790-8.
29. Duffy CM,. Measurement of health status, functional status, and quality of life in children with juvenile idiopathic arthritis: clinical science for the pediatrician. Pediatr Clin North Am 2005; 52: 359-72.
30. Malattia C, Damasio MB, Pistorio A, Ioseliani M, Vilca I, Valle M, et al. Development and preliminary validation of a paediatric-targeted MRI scoring system for the assessment of disease activity and damage in juvenile idiopathic arthritis. Ann Rheum Dis 2011; 70: 440-6.
31. Tynjala P, Vahasalo P, Tarkiainen M, Kroger L, Aalto K, Malin M, et al. Aggressive Combination Drug Therapy in Very Early Polyarticular Juvenile Idiopathic Arthritis (ACUTE-JIA): a multicentre randomised open-label clinical trial. Ann Rheum Dis 2011; 70: 1605-12.
32. Wallace CA, Giannini EH, Huang B, Itert L, Ruperto N, for the Childhood Arthritis and Rheumatology Research Alliance (CARRA), the Pediatric Rheumatology Collaborative Study Group (PRCSG), and the Paediatric Rheumatology International Trials Organisation (PRINTO). American College of Rheumatology provisional criteria for defining clinical inactive disease in select categories of juvenile idiopathic arthritis. Arthritis Care Res (Hoboken) 2011; 63: 929-36.