메뉴 건너뛰기




Volumn 133, Issue 3, 2014, Pages 624-631

"platinum resistant" ovarian cancer: What is it, who to treat and how to measure benefit?

Author keywords

Genotype; Histotype; Ovarian cancer; Platinum resistant; Treatment

Indexed keywords

9 AMINOCAMPTOTHECIN; ALTRETAMINE; ANTINEOPLASTIC AGENT; BELINOSTAT; BEVACIZUMAB; CAPECITABINE; CARBOPLATIN; CISPLATIN; COSITECAN; CYCLOSPORIN A; DASATINIB; DOCETAXEL; ENZASTAURIN; GEFITINIB; GEMCITABINE; IMATINIB; IROFULVEN; LAPATINIB; LEDOXANTRONE; MIFEPRISTONE; OXALIPLATIN; PACLITAXEL; PACLITAXEL POLIGLUMEX; PEMETREXED; SORAFENIB; TEMSIROLIMUS; TRABECTEDIN; UNINDEXED DRUG; VALSPODAR; VORINOSTAT;

EID: 84901674128     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2014.02.038     Document Type: Review
Times cited : (332)

References (70)
  • 2
    • 0026086870 scopus 로고
    • Second-line platinum therapy in patients with ovarian cancer previously treated with cisplatin
    • M. Markman, R. Rothman, T. Hakes, B. Reichman, W. Hoskins, and S. Rubin et al. Second-line platinum therapy in patients with ovarian cancer previously treated with cisplatin J Clin Oncol 9 3 1991 389 393
    • (1991) J Clin Oncol , vol.9 , Issue.3 , pp. 389-393
    • Markman, M.1    Rothman, R.2    Hakes, T.3    Reichman, B.4    Hoskins, W.5    Rubin, S.6
  • 3
    • 0031897980 scopus 로고    scopus 로고
    • Second-line therapy with paclitaxel and carboplatin for recurrent disease following first-line therapy with paclitaxel and platinum in ovarian or peritoneal carcinoma
    • P.G. Rose, N. Fusco, L. Fluellen, and M. Rodriguez Second-line therapy with paclitaxel and carboplatin for recurrent disease following first-line therapy with paclitaxel and platinum in ovarian or peritoneal carcinoma J Clin Oncol 16 4 1998 1494 1497
    • (1998) J Clin Oncol , vol.16 , Issue.4 , pp. 1494-1497
    • Rose, P.G.1    Fusco, N.2    Fluellen, L.3    Rodriguez, M.4
  • 4
    • 0035991033 scopus 로고    scopus 로고
    • Second-line with paclitaxel and carboplatin for recurrent disease following first paclitaxel and platinum compounds in ovarian carcinoma
    • G. Balbi, L. Di Prisco, R. Musone, A. Menditto, E. Cassese, and C. Balbi et al. Second-line with paclitaxel and carboplatin for recurrent disease following first paclitaxel and platinum compounds in ovarian carcinoma Eur J Gynaecol Oncol 23 4 2002 347 349
    • (2002) Eur J Gynaecol Oncol , vol.23 , Issue.4 , pp. 347-349
    • Balbi, G.1    Di Prisco, L.2    Musone, R.3    Menditto, A.4    Cassese, E.5    Balbi, C.6
  • 5
    • 70350786915 scopus 로고    scopus 로고
    • The combination of monthly carboplatin and weekly paclitaxel is highly active for the treatment of recurrent ovarian cancer
    • A.V. Hoekstra, J.A. Hurteau, C.V. Kirschner, and G.C. Rodriguez The combination of monthly carboplatin and weekly paclitaxel is highly active for the treatment of recurrent ovarian cancer Gynecol Oncol 115 3 2009 377 381
    • (2009) Gynecol Oncol , vol.115 , Issue.3 , pp. 377-381
    • Hoekstra, A.V.1    Hurteau, J.A.2    Kirschner, C.V.3    Rodriguez, G.C.4
  • 6
    • 0024522049 scopus 로고
    • Response of patients in phase II studies of chemotherapy in ovarian cancer: Implications for patient treatment and the design of phase II trials
    • G. Blackledge, F. Lawton, C. Redman, and K. Kelly Response of patients in phase II studies of chemotherapy in ovarian cancer: implications for patient treatment and the design of phase II trials Br J Cancer 59 4 1989 650 653
    • (1989) Br J Cancer , vol.59 , Issue.4 , pp. 650-653
    • Blackledge, G.1    Lawton, F.2    Redman, C.3    Kelly, K.4
  • 7
    • 0025103224 scopus 로고
    • Treatment of relapsed carcinoma of the ovary with cisplatin or carboplatin following initial treatment with these compounds
    • M.E. Gore, I. Fryatt, E. Wiltshaw, and T. Dawson Treatment of relapsed carcinoma of the ovary with cisplatin or carboplatin following initial treatment with these compounds Gynecol Oncol 36 2 1990 207 211
    • (1990) Gynecol Oncol , vol.36 , Issue.2 , pp. 207-211
    • Gore, M.E.1    Fryatt, I.2    Wiltshaw, E.3    Dawson, T.4
  • 8
    • 34548161162 scopus 로고    scopus 로고
    • Management of asymptomatic patients on follow-up for ovarian cancer with rising CA-125 concentrations
    • T.I. Goonewardene, M.R. Hall, and G.J. Rustin Management of asymptomatic patients on follow-up for ovarian cancer with rising CA-125 concentrations Lancet Oncol 8 9 2007 813 821
    • (2007) Lancet Oncol , vol.8 , Issue.9 , pp. 813-821
    • Goonewardene, T.I.1    Hall, M.R.2    Rustin, G.J.3
  • 9
    • 0031786482 scopus 로고    scopus 로고
    • Topotecan for the treatment of advanced epithelial ovarian cancer: An open-label phase II study in patients treated after prior chemotherapy that contained cisplatin or carboplatin and paclitaxel
    • M.A. Bookman, H. Malmstrom, G. Bolis, A. Gordon, A. Lissoni, and J.B. Krebs et al. Topotecan for the treatment of advanced epithelial ovarian cancer: an open-label phase II study in patients treated after prior chemotherapy that contained cisplatin or carboplatin and paclitaxel J Clin Oncol 16 10 1998 3345 3352
    • (1998) J Clin Oncol , vol.16 , Issue.10 , pp. 3345-3352
    • Bookman, M.A.1    Malmstrom, H.2    Bolis, G.3    Gordon, A.4    Lissoni, A.5    Krebs, J.B.6
  • 11
    • 77956813137 scopus 로고    scopus 로고
    • Prognostic relevance of uncommon ovarian histology in women with stage III/IV epithelial ovarian cancer
    • H.J. Mackay, M.F. Brady, A.M. Oza, A. Reuss, E. Pujade-Lauraine, and A.M. Swart et al. Prognostic relevance of uncommon ovarian histology in women with stage III/IV epithelial ovarian cancer Int J Gynecol Cancer 20 6 2010 945 952
    • (2010) Int J Gynecol Cancer , vol.20 , Issue.6 , pp. 945-952
    • Mackay, H.J.1    Brady, M.F.2    Oza, A.M.3    Reuss, A.4    Pujade-Lauraine, E.5    Swart, A.M.6
  • 12
    • 84864026311 scopus 로고    scopus 로고
    • BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: A report from the Australian Ovarian Cancer Study Group
    • K. Alsop, S. Fereday, C. Meldrum, A. deFazio, C. Emmanuel, and J. George et al. BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group J Clin Oncol 30 21 2012 2654 2663
    • (2012) J Clin Oncol , vol.30 , Issue.21 , pp. 2654-2663
    • Alsop, K.1    Fereday, S.2    Meldrum, C.3    Defazio, A.4    Emmanuel, C.5    George, J.6
  • 13
    • 84864276664 scopus 로고    scopus 로고
    • Germline BRCA1 and BRCA2 mutations in ovarian cancer: Utility of a histology-based referral strategy
    • K.A. Schrader, J. Hurlburt, S.E. Kalloger, S. Hansford, S. Young, and D.G. Huntsman et al. Germline BRCA1 and BRCA2 mutations in ovarian cancer: utility of a histology-based referral strategy Obstet Gynecol 120 2 Pt 1 2012 235 240
    • (2012) Obstet Gynecol , vol.120 , Issue.2 PART 1 , pp. 235-240
    • Schrader, K.A.1    Hurlburt, J.2    Kalloger, S.E.3    Hansford, S.4    Young, S.5    Huntsman, D.G.6
  • 15
    • 0037403380 scopus 로고    scopus 로고
    • Improved survival in women with BRCA-associated ovarian carcinoma
    • I. Cass, R.L. Baldwin, T. Varkey, R. Moslehi, S.A. Narod, and B.Y. Karlan Improved survival in women with BRCA-associated ovarian carcinoma Cancer 97 9 2003 2187 2195
    • (2003) Cancer , vol.97 , Issue.9 , pp. 2187-2195
    • Cass, I.1    Baldwin, R.L.2    Varkey, T.3    Moslehi, R.4    Narod, S.A.5    Karlan, B.Y.6
  • 16
    • 57149093237 scopus 로고    scopus 로고
    • BRCAness" syndrome in ovarian cancer: A case-control study describing the clinical features and outcome of patients with epithelial ovarian cancer associated with BRCA1 and BRCA2 mutations
    • D.S. Tan, C. Rothermundt, K. Thomas, E. Bancroft, R. Eeles, and S. Shanley et al. "BRCAness" syndrome in ovarian cancer: a case-control study describing the clinical features and outcome of patients with epithelial ovarian cancer associated with BRCA1 and BRCA2 mutations J Clin Oncol 26 34 2008 5530 5536
    • (2008) J Clin Oncol , vol.26 , Issue.34 , pp. 5530-5536
    • Tan, D.S.1    Rothermundt, C.2    Thomas, K.3    Bancroft, E.4    Eeles, R.5    Shanley, S.6
  • 17
    • 79955390596 scopus 로고    scopus 로고
    • Chemosensitivity and outcome of BRCA1- and BRCA2-associated ovarian cancer patients after first-line chemotherapy compared with sporadic ovarian cancer patients
    • P.M. Vencken, M. Kriege, D. Hoogwerf, S. Beugelink, M.E. van der Burg, and M.J. Hooning et al. Chemosensitivity and outcome of BRCA1- and BRCA2-associated ovarian cancer patients after first-line chemotherapy compared with sporadic ovarian cancer patients Ann Oncol 22 6 2011 1346 1352
    • (2011) Ann Oncol , vol.22 , Issue.6 , pp. 1346-1352
    • Vencken, P.M.1    Kriege, M.2    Hoogwerf, D.3    Beugelink, S.4    Van Der Burg, M.E.5    Hooning, M.J.6
  • 18
    • 0034307160 scopus 로고    scopus 로고
    • BRCA1 promoter region hypermethylation in ovarian carcinoma: A population-based study
    • R.L. Baldwin, E. Nemeth, H. Tran, H. Shvartsman, I. Cass, and S. Narod et al. BRCA1 promoter region hypermethylation in ovarian carcinoma: a population-based study Cancer Res 60 19 2000 5329 5333
    • (2000) Cancer Res , vol.60 , Issue.19 , pp. 5329-5333
    • Baldwin, R.L.1    Nemeth, E.2    Tran, H.3    Shvartsman, H.4    Cass, I.5    Narod, S.6
  • 19
  • 20
    • 9444222467 scopus 로고    scopus 로고
    • Somatic and germline mutations of the BRCA2 gene in sporadic ovarian cancer
    • K.A. Foster, P. Harrington, J. Kerr, P. Russell, R.A. DiCioccio, and I.V. Scott et al. Somatic and germline mutations of the BRCA2 gene in sporadic ovarian cancer Cancer Res 56 16 1996 3622 3625
    • (1996) Cancer Res , vol.56 , Issue.16 , pp. 3622-3625
    • Foster, K.A.1    Harrington, P.2    Kerr, J.3    Russell, P.4    Dicioccio, R.A.5    Scott, I.V.6
  • 22
    • 10744233204 scopus 로고    scopus 로고
    • EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer
    • L. Hughes-Davies, D. Huntsman, M. Ruas, F. Fuks, J. Bye, and S.F. Chin et al. EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer Cell 115 5 2003 523 535
    • (2003) Cell , vol.115 , Issue.5 , pp. 523-535
    • Hughes-Davies, L.1    Huntsman, D.2    Ruas, M.3    Fuks, F.4    Bye, J.5    Chin, S.F.6
  • 23
    • 0038075462 scopus 로고    scopus 로고
    • Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors
    • T. Taniguchi, M. Tischkowitz, N. Ameziane, S.V. Hodgson, C.G. Mathew, and H. Joenje et al. Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors Nat Med 9 5 2003 568 574
    • (2003) Nat Med , vol.9 , Issue.5 , pp. 568-574
    • Taniguchi, T.1    Tischkowitz, M.2    Ameziane, N.3    Hodgson, S.V.4    Mathew, C.G.5    Joenje, H.6
  • 24
    • 33748065304 scopus 로고    scopus 로고
    • Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition
    • N. McCabe, N.C. Turner, C.J. Lord, K. Kluzek, A. Bialkowska, and S. Swift et al. Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition Cancer Res 66 16 2006 8109 8115
    • (2006) Cancer Res , vol.66 , Issue.16 , pp. 8109-8115
    • McCabe, N.1    Turner, N.C.2    Lord, C.J.3    Kluzek, K.4    Bialkowska, A.5    Swift, S.6
  • 25
    • 2342596529 scopus 로고    scopus 로고
    • The Fanconi Anemia/BRCA signaling pathway: Disruption in cisplatin-sensitive ovarian cancers
    • A.D. D'Andrea The Fanconi Anemia/BRCA signaling pathway: disruption in cisplatin-sensitive ovarian cancers Cell Cycle 2 4 2003 290 292
    • (2003) Cell Cycle , vol.2 , Issue.4 , pp. 290-292
    • D'Andrea, A.D.1
  • 26
    • 25444485414 scopus 로고    scopus 로고
    • CpG island methylation of DNA damage response genes in advanced ovarian cancer
    • J.M. Teodoridis, J. Hall, S. Marsh, H.D. Kannall, C. Smyth, and J. Curto et al. CpG island methylation of DNA damage response genes in advanced ovarian cancer Cancer Res 65 19 2005 8961 8967
    • (2005) Cancer Res , vol.65 , Issue.19 , pp. 8961-8967
    • Teodoridis, J.M.1    Hall, J.2    Marsh, S.3    Kannall, H.D.4    Smyth, C.5    Curto, J.6
  • 27
    • 77955894453 scopus 로고    scopus 로고
    • Gene expression profile of BRCAness that correlates with responsiveness to chemotherapy and with outcome in patients with epithelial ovarian cancer
    • P.A. Konstantinopoulos, D. Spentzos, B.Y. Karlan, T. Taniguchi, E. Fountzilas, and N. Francoeur et al. Gene expression profile of BRCAness that correlates with responsiveness to chemotherapy and with outcome in patients with epithelial ovarian cancer J Clin Oncol 28 22 2010 3555 3561
    • (2010) J Clin Oncol , vol.28 , Issue.22 , pp. 3555-3561
    • Konstantinopoulos, P.A.1    Spentzos, D.2    Karlan, B.Y.3    Taniguchi, T.4    Fountzilas, E.5    Francoeur, N.6
  • 28
    • 79959838081 scopus 로고    scopus 로고
    • Integrated genomic analyses of ovarian carcinoma
    • Cancer Genome Atlas Research N
    • Cancer Genome Atlas Research N Integrated genomic analyses of ovarian carcinoma Nature 474 7353 2011 609 615
    • (2011) Nature , vol.474 , Issue.7353 , pp. 609-615
  • 30
    • 0345256652 scopus 로고    scopus 로고
    • Cisplatin: Mode of cytotoxic action and molecular basis of resistance
    • Z.H. Siddik Cisplatin: mode of cytotoxic action and molecular basis of resistance Oncogene 22 47 2003 7265 7279
    • (2003) Oncogene , vol.22 , Issue.47 , pp. 7265-7279
    • Siddik, Z.H.1
  • 32
    • 0028141961 scopus 로고
    • Messenger RNA levels of XPAC and ERCC1 in ovarian cancer tissue correlate with response to platinum-based chemotherapy
    • M. Dabholkar, J. Vionnet, F. Bostick-Bruton, J.J. Yu, and E. Reed Messenger RNA levels of XPAC and ERCC1 in ovarian cancer tissue correlate with response to platinum-based chemotherapy J Clin Invest 94 2 1994 703 708
    • (1994) J Clin Invest , vol.94 , Issue.2 , pp. 703-708
    • Dabholkar, M.1    Vionnet, J.2    Bostick-Bruton, F.3    Yu, J.J.4    Reed, E.5
  • 34
    • 42349096328 scopus 로고    scopus 로고
    • Secondary BRCA1 mutations in BRCA1-mutated ovarian carcinomas with platinum resistance
    • E.M. Swisher, W. Sakai, B.Y. Karlan, K. Wurz, N. Urban, and T. Taniguchi Secondary BRCA1 mutations in BRCA1-mutated ovarian carcinomas with platinum resistance Cancer Res 68 8 2008 2581 2586
    • (2008) Cancer Res , vol.68 , Issue.8 , pp. 2581-2586
    • Swisher, E.M.1    Sakai, W.2    Karlan, B.Y.3    Wurz, K.4    Urban, N.5    Taniguchi, T.6
  • 35
    • 39849106300 scopus 로고    scopus 로고
    • Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers
    • W. Sakai, E.M. Swisher, B.Y. Karlan, M.K. Agarwal, J. Higgins, and C. Friedman et al. Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers Nature 451 7182 2008 1116 1120
    • (2008) Nature , vol.451 , Issue.7182 , pp. 1116-1120
    • Sakai, W.1    Swisher, E.M.2    Karlan, B.Y.3    Agarwal, M.K.4    Higgins, J.5    Friedman, C.6
  • 36
    • 84878102548 scopus 로고    scopus 로고
    • Mechanisms and insights into drug resistance in cancer
    • H. Zahreddine, and K.L. Borden Mechanisms and insights into drug resistance in cancer Front Pharmacol 4 2013 28
    • (2013) Front Pharmacol , vol.4 , pp. 28
    • Zahreddine, H.1    Borden, K.L.2
  • 37
    • 16844368698 scopus 로고    scopus 로고
    • Tumour stem cells and drug resistance
    • M. Dean, T. Fojo, and S. Bates Tumour stem cells and drug resistance Nat Rev Cancer 5 4 2005 275 284
    • (2005) Nat Rev Cancer , vol.5 , Issue.4 , pp. 275-284
    • Dean, M.1    Fojo, T.2    Bates, S.3
  • 38
    • 33750584024 scopus 로고    scopus 로고
    • Tumour stem cell-targeted treatment: Elimination or differentiation
    • C. Massard, E. Deutsch, and J.C. Soria Tumour stem cell-targeted treatment: elimination or differentiation Ann Oncol 17 11 2006 1620 1624
    • (2006) Ann Oncol , vol.17 , Issue.11 , pp. 1620-1624
    • Massard, C.1    Deutsch, E.2    Soria, J.C.3
  • 39
    • 35648999534 scopus 로고    scopus 로고
    • Recent advances in cancer stem/progenitor cell research: Therapeutic implications for overcoming resistance to the most aggressive cancers
    • M. Mimeault, R. Hauke, P.P. Mehta, and S.K. Batra Recent advances in cancer stem/progenitor cell research: therapeutic implications for overcoming resistance to the most aggressive cancers J Cell Mol Med 11 5 2007 981 1011
    • (2007) J Cell Mol Med , vol.11 , Issue.5 , pp. 981-1011
    • Mimeault, M.1    Hauke, R.2    Mehta, P.P.3    Batra, S.K.4
  • 40
    • 40749150740 scopus 로고    scopus 로고
    • CD133 + HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway
    • S. Ma, T.K. Lee, B.J. Zheng, K.W. Chan, and X.Y. Guan CD133 + HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway Oncogene 27 12 2008 1749 1758
    • (2008) Oncogene , vol.27 , Issue.12 , pp. 1749-1758
    • Ma, S.1    Lee, T.K.2    Zheng, B.J.3    Chan, K.W.4    Guan, X.Y.5
  • 41
    • 34548455927 scopus 로고    scopus 로고
    • Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
    • P.C. Hermann, S.L. Huber, T. Herrler, A. Aicher, J.W. Ellwart, and M. Guba et al. Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer Cell Stem Cell 1 3 2007 313 323
    • (2007) Cell Stem Cell , vol.1 , Issue.3 , pp. 313-323
    • Hermann, P.C.1    Huber, S.L.2    Herrler, T.3    Aicher, A.4    Ellwart, J.W.5    Guba, M.6
  • 42
    • 70549084933 scopus 로고    scopus 로고
    • Integrated genomics of chemotherapy resistant ovarian cancer: A role for extracellular matrix, TGFbeta and regulating microRNAs
    • J. Helleman, M.P. Jansen, C. Burger, M.E. van der Burg, and E.M. Berns Integrated genomics of chemotherapy resistant ovarian cancer: a role for extracellular matrix, TGFbeta and regulating microRNAs Int J Biochem Cell Biol 42 1 2010 25 30
    • (2010) Int J Biochem Cell Biol , vol.42 , Issue.1 , pp. 25-30
    • Helleman, J.1    Jansen, M.P.2    Burger, C.3    Van Der Burg, M.E.4    Berns, E.M.5
  • 43
    • 52649085237 scopus 로고    scopus 로고
    • Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome
    • R.W. Tothill, A.V. Tinker, J. George, R. Brown, S.B. Fox, and S. Lade et al. Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome Clin Cancer Res 14 16 2008 5198 5208
    • (2008) Clin Cancer Res , vol.14 , Issue.16 , pp. 5198-5208
    • Tothill, R.W.1    Tinker, A.V.2    George, J.3    Brown, R.4    Fox, S.B.5    Lade, S.6
  • 44
    • 84863393080 scopus 로고    scopus 로고
    • Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
    • M. Gerlinger, A.J. Rowan, S. Horswell, J. Larkin, D. Endesfelder, and E. Gronroos et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing N Engl J Med 366 10 2012 883 892
    • (2012) N Engl J Med , vol.366 , Issue.10 , pp. 883-892
    • Gerlinger, M.1    Rowan, A.J.2    Horswell, S.3    Larkin, J.4    Endesfelder, D.5    Gronroos, E.6
  • 45
    • 84885092663 scopus 로고    scopus 로고
    • Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling
    • A. Bashashati, G. Ha, A. Tone, J. Ding, L.M. Prentice, and A. Roth et al. Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling J Pathol 231 1 2013 21 34
    • (2013) J Pathol , vol.231 , Issue.1 , pp. 21-34
    • Bashashati, A.1    Ha, G.2    Tone, A.3    Ding, J.4    Prentice, L.M.5    Roth, A.6
  • 46
    • 36849056497 scopus 로고    scopus 로고
    • Phase II study of bevacizumab in patients with platinum-resistant ovarian cancer or peritoneal serous cancer
    • S.A. Cannistra, U.A. Matulonis, R.T. Penson, J. Hambleton, J. Dupont, and H. Mackey et al. Phase II study of bevacizumab in patients with platinum-resistant ovarian cancer or peritoneal serous cancer J Clin Oncol 25 33 2007 5180 5186
    • (2007) J Clin Oncol , vol.25 , Issue.33 , pp. 5180-5186
    • Cannistra, S.A.1    Matulonis, U.A.2    Penson, R.T.3    Hambleton, J.4    Dupont, J.5    Mackey, H.6
  • 47
    • 36849019301 scopus 로고    scopus 로고
    • Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: A Gynecologic Oncology Group Study
    • R.A. Burger, M.W. Sill, B.J. Monk, B.E. Greer, and J.I. Sorosky Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: a Gynecologic Oncology Group Study J Clin Oncol 25 33 2007 5165 5171
    • (2007) J Clin Oncol , vol.25 , Issue.33 , pp. 5165-5171
    • Burger, R.A.1    Sill, M.W.2    Monk, B.J.3    Greer, B.E.4    Sorosky, J.I.5
  • 48
    • 35348904080 scopus 로고    scopus 로고
    • Bevacizumab plus cyclophosphamide in heavily pretreated patients with recurrent ovarian cancer
    • J.C. Chura, K. Van Iseghem, L.S. Downs Jr., L.F. Carson, and P.L. Judson Bevacizumab plus cyclophosphamide in heavily pretreated patients with recurrent ovarian cancer Gynecol Oncol 107 2 2007 326 330
    • (2007) Gynecol Oncol , vol.107 , Issue.2 , pp. 326-330
    • Chura, J.C.1    Van Iseghem, K.2    Downs, Jr.L.S.3    Carson, L.F.4    Judson, P.L.5
  • 49
    • 78149433404 scopus 로고    scopus 로고
    • Bevacizumab plus low-dose metronomic oral cyclophosphamide in heavily pretreated patients with recurrent ovarian cancer
    • A. Sanchez-Munoz, C. Mendiola, E. Perez-Ruiz, C.A. Rodriguez-Sanchez, J.M. Jurado, and L. Alonso-Carrion et al. Bevacizumab plus low-dose metronomic oral cyclophosphamide in heavily pretreated patients with recurrent ovarian cancer Oncology 79 1-2 2010 98 104
    • (2010) Oncology , vol.79 , Issue.12 , pp. 98-104
    • Sanchez-Munoz, A.1    Mendiola, C.2    Perez-Ruiz, E.3    Rodriguez-Sanchez, C.A.4    Jurado, J.M.5    Alonso-Carrion, L.6
  • 50
    • 83055173012 scopus 로고    scopus 로고
    • Addition of bevacizumab to weekly paclitaxel significantly improves progression-free survival in heavily pretreated recurrent epithelial ovarian cancer
    • [author reply -2]
    • M. Markman Addition of bevacizumab to weekly paclitaxel significantly improves progression-free survival in heavily pretreated recurrent epithelial ovarian cancer Gynecol Oncol 124 1 2012 171 [author reply -2]
    • (2012) Gynecol Oncol , vol.124 , Issue.1 , pp. 171
    • Markman, M.1
  • 51
    • 84894044956 scopus 로고    scopus 로고
    • FInal overall survival (OS) results from AURELIA, an open-label randomised phase III trial of chemotherapy (CT) with or without bevacizumab (BEV) for platinum-resistant recurrent ovarian cancer (OS). European Cancer Congress LBA 5
    • P. Witteveen, A. Lortholary, T. Fehm, A. Poveda, A. Reuss, and H. Havsteen et al. FInal overall survival (OS) results from AURELIA, an open-label randomised phase III trial of chemotherapy (CT) with or without bevacizumab (BEV) for platinum-resistant recurrent ovarian cancer (OS). European Cancer Congress LBA 5 Eur J Cancer 49 Suppl. 3 2013 S3
    • (2013) Eur J Cancer , vol.49 , Issue.SUPPL. 3 , pp. 3
    • Witteveen, P.1    Lortholary, A.2    Fehm, T.3    Poveda, A.4    Reuss, A.5    Havsteen, H.6
  • 52
    • 84894070693 scopus 로고    scopus 로고
    • A phase III, randomized, double-blind trial of weekly paclitaxel plus the angiopoeitin 1 and 2 inhibitor, trabananib, or placebo in women with recurrent ovarian cancer: TRINOVA-1. European Cancer Congress LBA 41
    • B.J. Monk, A. Poveda, I. Vergote, F. Raspagliesi, K. Fujiwara, and D.S. Bae et al. A phase III, randomized, double-blind trial of weekly paclitaxel plus the angiopoeitin 1 and 2 inhibitor, trabananib, or placebo in women with recurrent ovarian cancer: TRINOVA-1. European Cancer Congress LBA 41 Eur J Cancer 49 Suppl. 2 2013 S18
    • (2013) Eur J Cancer , vol.49 , Issue.SUPPL. 2 , pp. 18
    • Monk, B.J.1    Poveda, A.2    Vergote, I.3    Raspagliesi, F.4    Fujiwara, K.5    Bae, D.S.6
  • 53
    • 77957684487 scopus 로고    scopus 로고
    • Early versus delayed treatment of relapsed ovarian cancer (MRC OV05/EORTC 55955): A randomised trial
    • G.J. Rustin, M.E. van der Burg, C.L. Griffin, D. Guthrie, A. Lamont, and G.C. Jayson et al. Early versus delayed treatment of relapsed ovarian cancer (MRC OV05/EORTC 55955): a randomised trial Lancet 376 9747 2010 1155 1163
    • (2010) Lancet , vol.376 , Issue.9747 , pp. 1155-1163
    • Rustin, G.J.1    Van Der Burg, M.E.2    Griffin, C.L.3    Guthrie, D.4    Lamont, A.5    Jayson, G.C.6
  • 54
    • 0036919813 scopus 로고    scopus 로고
    • Association between in vitro platinum resistance in the EDR assay and clinical outcomes for ovarian cancer patients
    • R.W. Holloway, R.S. Mehta, N.J. Finkler, K.T. Li, C.E. McLaren, and R.J. Parker et al. Association between in vitro platinum resistance in the EDR assay and clinical outcomes for ovarian cancer patients Gynecol Oncol 87 1 2002 8 16
    • (2002) Gynecol Oncol , vol.87 , Issue.1 , pp. 8-16
    • Holloway, R.W.1    Mehta, R.S.2    Finkler, N.J.3    Li, K.T.4    McLaren, C.E.5    Parker, R.J.6
  • 55
    • 33645336304 scopus 로고    scopus 로고
    • Progression-free interval in ovarian cancer and predictive value of an ex vivo chemoresponse assay
    • H. Gallion, W.A. Christopherson, R.L. Coleman, L. DeMars, T. Herzog, and S. Hosford et al. Progression-free interval in ovarian cancer and predictive value of an ex vivo chemoresponse assay Int J Gynecol Cancer 16 1 2006 194 201
    • (2006) Int J Gynecol Cancer , vol.16 , Issue.1 , pp. 194-201
    • Gallion, H.1    Christopherson, W.A.2    Coleman, R.L.3    Demars, L.4    Herzog, T.5    Hosford, S.6
  • 56
    • 77954086743 scopus 로고    scopus 로고
    • Chemosensitivity testing with ChemoFx and overall survival in primary ovarian cancer
    • [68 e1-6]
    • T.J. Herzog, T.C. Krivak, A.N. Fader, and R.L. Coleman Chemosensitivity testing with ChemoFx and overall survival in primary ovarian cancer Am J Obstet Gynecol 203 1 2010 [68 e1-6]
    • (2010) Am J Obstet Gynecol , vol.203 , Issue.1
    • Herzog, T.J.1    Krivak, T.C.2    Fader, A.N.3    Coleman, R.L.4
  • 57
    • 84886093926 scopus 로고    scopus 로고
    • A prospective study evaluating the clinical relevance of a chemoresponse assay for treatment of patients with persistent or recurrent ovarian cancer
    • T. Rutherford, J. Orr Jr., E. Grendys Jr., R. Edwards, T.C. Krivak, and R. Holloway et al. A prospective study evaluating the clinical relevance of a chemoresponse assay for treatment of patients with persistent or recurrent ovarian cancer Gynecol Oncol 131 1 2013 276
    • (2013) Gynecol Oncol , vol.131 , Issue.1 , pp. 276
    • Rutherford, T.1    Orr, Jr.J.2    Grendys, Jr.E.3    Edwards, R.4    Krivak, T.C.5    Holloway, R.6
  • 58
    • 20444443432 scopus 로고    scopus 로고
    • Identifying patients unlikely to benefit from further chemotherapy: A descriptive study of outcome at each relapse in ovarian cancer
    • P.J. Hoskins, and N. Le Identifying patients unlikely to benefit from further chemotherapy: a descriptive study of outcome at each relapse in ovarian cancer Gynecol Oncol 97 3 2005 862 869
    • (2005) Gynecol Oncol , vol.97 , Issue.3 , pp. 862-869
    • Hoskins, P.J.1    Le, N.2
  • 59
    • 0035281501 scopus 로고    scopus 로고
    • Does palliative chemotherapy palliate? Evaluation of expectations, outcomes, and costs in women receiving chemotherapy for advanced ovarian cancer
    • C. Doyle, M. Crump, M. Pintilie, and A.M. Oza Does palliative chemotherapy palliate? Evaluation of expectations, outcomes, and costs in women receiving chemotherapy for advanced ovarian cancer J Clin Oncol 19 5 2001 1266 1274
    • (2001) J Clin Oncol , vol.19 , Issue.5 , pp. 1266-1274
    • Doyle, C.1    Crump, M.2    Pintilie, M.3    Oza, A.M.4
  • 60
  • 61
    • 0036407202 scopus 로고    scopus 로고
    • Randomized trial of single agent paclitaxel given weekly versus every three weeks and with peroral versus intravenous steroid premedication to patients with ovarian cancer previously treated with platinum
    • P. Rosenberg, H. Andersson, K. Boman, M. Ridderheim, B. Sorbe, and U. Puistola et al. Randomized trial of single agent paclitaxel given weekly versus every three weeks and with peroral versus intravenous steroid premedication to patients with ovarian cancer previously treated with platinum Acta Oncol 41 5 2002 418 424
    • (2002) Acta Oncol , vol.41 , Issue.5 , pp. 418-424
    • Rosenberg, P.1    Andersson, H.2    Boman, K.3    Ridderheim, M.4    Sorbe, B.5    Puistola, U.6
  • 62
    • 0035879099 scopus 로고    scopus 로고
    • Recurrent epithelial ovarian carcinoma: A randomized phase III study of pegylated liposomal doxorubicin versus topotecan
    • A.N. Gordon, J.T. Fleagle, D. Guthrie, D.E. Parkin, M.E. Gore, and A.J. Lacave Recurrent epithelial ovarian carcinoma: a randomized phase III study of pegylated liposomal doxorubicin versus topotecan J Clin Oncol 19 14 2001 3312 3322
    • (2001) J Clin Oncol , vol.19 , Issue.14 , pp. 3312-3322
    • Gordon, A.N.1    Fleagle, J.T.2    Guthrie, D.3    Parkin, D.E.4    Gore, M.E.5    Lacave, A.J.6
  • 63
    • 3042792377 scopus 로고    scopus 로고
    • Randomised controlled trial comparing single agent paclitaxel vs epidoxorubicin plus paclitaxel in patients with advanced ovarian cancer in early progression after platinum-based chemotherapy: An Italian Collaborative Study from the Mario Negri Institute, Milan, G.O.N.O. (Gruppo Oncologico Nord Ovest) group and I.O.R. (Istituto Oncologico Romagnolo) group
    • A. Buda, I. Floriani, R. Rossi, N. Colombo, V. Torri, and P.F. Conte et al. Randomised controlled trial comparing single agent paclitaxel vs epidoxorubicin plus paclitaxel in patients with advanced ovarian cancer in early progression after platinum-based chemotherapy: an Italian Collaborative Study from the Mario Negri Institute, Milan, G.O.N.O. (Gruppo Oncologico Nord Ovest) group and I.O.R. (Istituto Oncologico Romagnolo) group Br J Cancer 90 11 2004 2112 2117
    • (2004) Br J Cancer , vol.90 , Issue.11 , pp. 2112-2117
    • Buda, A.1    Floriani, I.2    Rossi, R.3    Colombo, N.4    Torri, V.5    Conte, P.F.6
  • 64
    • 34447570846 scopus 로고    scopus 로고
    • Randomized phase III trial of gemcitabine compared with pegylated liposomal doxorubicin in patients with platinum-resistant ovarian cancer
    • D.G. Mutch, M. Orlando, T. Goss, M.G. Teneriello, A.N. Gordon, and S.D. McMeekin et al. Randomized phase III trial of gemcitabine compared with pegylated liposomal doxorubicin in patients with platinum-resistant ovarian cancer J Clin Oncol 25 19 2007 2811 2818
    • (2007) J Clin Oncol , vol.25 , Issue.19 , pp. 2811-2818
    • Mutch, D.G.1    Orlando, M.2    Goss, T.3    Teneriello, M.G.4    Gordon, A.N.5    McMeekin, S.D.6
  • 65
    • 67549084366 scopus 로고    scopus 로고
    • Topotecan versus treosulfan, an alkylating agent, in patients with epithelial ovarian cancer and relapse within 12 months following 1st-line platinum/paclitaxel chemotherapy. A prospectively randomized phase III trial by the Arbeitsgemeinschaft Gynaekologische Onkologie Ovarian Cancer Study Group (AGO-OVAR)
    • W. Meier, A. du Bois, A. Reuss, W. Kuhn, S. Olbricht, and M. Gropp et al. Topotecan versus treosulfan, an alkylating agent, in patients with epithelial ovarian cancer and relapse within 12 months following 1st-line platinum/paclitaxel chemotherapy. A prospectively randomized phase III trial by the Arbeitsgemeinschaft Gynaekologische Onkologie Ovarian Cancer Study Group (AGO-OVAR) Gynecol Oncol 114 2 2009 199 205
    • (2009) Gynecol Oncol , vol.114 , Issue.2 , pp. 199-205
    • Meier, W.1    Du Bois, A.2    Reuss, A.3    Kuhn, W.4    Olbricht, S.5    Gropp, M.6
  • 66
    • 68749089764 scopus 로고    scopus 로고
    • Phase 3 randomised study of canfosfamide (Telcyta, TLK286) versus pegylated liposomal doxorubicin or topotecan as third-line therapy in patients with platinum-refractory or -resistant ovarian cancer
    • I. Vergote, N. Finkler, J. del Campo, A. Lohr, J. Hunter, and D. Matei et al. Phase 3 randomised study of canfosfamide (Telcyta, TLK286) versus pegylated liposomal doxorubicin or topotecan as third-line therapy in patients with platinum-refractory or -resistant ovarian cancer Eur J Cancer 45 13 2009 2324 2332
    • (2009) Eur J Cancer , vol.45 , Issue.13 , pp. 2324-2332
    • Vergote, I.1    Finkler, N.2    Del Campo, J.3    Lohr, A.4    Hunter, J.5    Matei, D.6
  • 67
    • 77955491837 scopus 로고    scopus 로고
    • Trabectedin plus pegylated liposomal Doxorubicin in recurrent ovarian cancer
    • B.J. Monk, T.J. Herzog, S.B. Kaye, C.N. Krasner, J.B. Vermorken, and F.M. Muggia et al. Trabectedin plus pegylated liposomal Doxorubicin in recurrent ovarian cancer J Clin Oncol 28 19 2010 3107 3114
    • (2010) J Clin Oncol , vol.28 , Issue.19 , pp. 3107-3114
    • Monk, B.J.1    Herzog, T.J.2    Kaye, S.B.3    Krasner, C.N.4    Vermorken, J.B.5    Muggia, F.M.6
  • 68
    • 84869109927 scopus 로고    scopus 로고
    • Randomized, open-label, phase III study comparing patupilone (EPO906) with pegylated liposomal doxorubicin in platinum-refractory or -resistant patients with recurrent epithelial ovarian, primary fallopian tube, or primary peritoneal cancer
    • N. Colombo, E. Kutarska, M. Dimopoulos, D.S. Bae, I. Rzepka-Gorska, and M. Bidzinski et al. Randomized, open-label, phase III study comparing patupilone (EPO906) with pegylated liposomal doxorubicin in platinum-refractory or -resistant patients with recurrent epithelial ovarian, primary fallopian tube, or primary peritoneal cancer J Clin Oncol 30 31 2012 3841 3847
    • (2012) J Clin Oncol , vol.30 , Issue.31 , pp. 3841-3847
    • Colombo, N.1    Kutarska, E.2    Dimopoulos, M.3    Bae, D.S.4    Rzepka-Gorska, I.5    Bidzinski, M.6
  • 69
    • 84903688861 scopus 로고    scopus 로고
    • Weekly AUC2 carboplatin in acquired platinum-resistant ovarian cancer with or without oral phenoxodiol, a sensitizer of platinum cytotoxicity: The phase III OVATURE multicenter randomized study
    • doi:10.1093/annonc/mdt515 (published online ahead of print Dec 10, 2013)
    • C. Fotopoulou, I. Vergote, P. Mainwaring, M. Bidzinski, J.B. Vermorken, and S.A. Ghamande et al. Weekly AUC2 carboplatin in acquired platinum-resistant ovarian cancer with or without oral phenoxodiol, a sensitizer of platinum cytotoxicity: the phase III OVATURE multicenter randomized study (published online ahead of print Dec 10, 2013) Ann Oncol 2013 http://dx.doi.org/10.1093/ annonc/mdt515
    • (2013) Ann Oncol
    • Fotopoulou, C.1    Vergote, I.2    Mainwaring, P.3    Bidzinski, M.4    Vermorken, J.B.5    Ghamande, S.A.6
  • 70
    • 84891854386 scopus 로고    scopus 로고
    • PRECEDENT: A randomised phase II trial comparing Vintafolide (EC145) and pegylated liposomal doxorubicin (PLD) in combination versus PLD alone in patients with platinum-resistant ovarian cancer
    • R.W. Naumann, R. Coleman, C. Burger, E.A. Sausville, E. Kutarska, and S.A. Ghamande et al. PRECEDENT: A randomised phase II trial comparing Vintafolide (EC145) and pegylated liposomal doxorubicin (PLD) in combination versus PLD alone in patients with platinum-resistant ovarian cancer J Clin Oncol 31 35 2013 4400 4408
    • (2013) J Clin Oncol , vol.31 , Issue.35 , pp. 4400-4408
    • Naumann, R.W.1    Coleman, R.2    Burger, C.3    Sausville, E.A.4    Kutarska, E.5    Ghamande, S.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.