Acridone alkaloids from Glycosmis chlorosperma as DYRK1A inhibitors

Journal of Natural Products

Volumn 77, Issue 5, 2014, Pages 1117-1122

  Beniddir, Mehdi A ^a   Le Borgne, Erell ^a   Iorga, Bogdan I ^a   Loaëc, Nadège ^b,c   Lozach, Olivier ^b   Meijer, Laurent ^b,c   Awang, Khalijah ^d   Litaudon, Marc ^a  

^a CNRS   (France)

^b STATION BIOLOGIQUE   (France)

^c Centre de Perharidy   (France)

^d UNIVERSITY OF MALAYA   (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

ACRIFOLINE; ATALAPHYLLIDINE; CASEIN KINASE I; CHLOROSPERMINE A; CHLOROSPERMINE B; CYCLIN DEPENDENT KINASE; GLYCOGEN SYNTHASE KINASE 3; PLANT EXTRACT; PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CHROMATOGRAPHY; CONTROLLED STUDY; DRUG ISOLATION; ENZYME ASSAY; ENZYME INHIBITION; EVALUATION STUDY; GLYCOSMIS CHLOROSPERMA; HUMAN; IC 50; IN VITRO STUDY; MEDICINAL PLANT; MOLECULAR DOCKING; MOLECULAR MODEL; NONHUMAN; RAT; RUTACEAE;

ACRIDONES; ALKALOIDS; MALAYSIA; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; RUTACEAE;

EID: 84901664872     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np400856h     Document Type: Article

References (34)

1. Liu, J.; Hu, Y.; Waller, D. L.; Wang, J.; Liu, Q. Nat. Prod. Rep. 2012, 29, 392-403
2. Becker, W.; Sippl, W. FEBS J. 2011, 278, 246-256
3. Marti, G.; Eparvier, V.; Morleo, B.; Ven, J.; Apel, C.; Bodo, B.; Amand, S.; Dumontet, V.; Lozach, O.; Meijer, L.; Guéritte, F.; Litaudon, M. Molecules 2013, 18, 3018-3027
4. Apel, C.; Dumontet, V.; Lozach, O.; Meijer, L.; Guéritte, F.; Litaudon, M. Phytochem. Lett. 2012, 5, 814-818
5. Sprengel, K. Syst. Vegetabilium 1827, 4, 162
6. Whitmore, T. C. In Tree Flora of Malaya; A Manual for the Forester; Whitmore, T. C., Ed.; Longman: Hong Kong, 1972; Vol. 1, pp 380-382.
7. Wang, J.; Yang, X.; Di, Y.; Wang, Y.; Shen, Y.; Hao, X. J. Nat. Prod. 2006, 69, 778-782
8. Lukaseder, B.; Vajrodaya, S.; Hehenberger, T.; Seger, C.; Nagl, M.; Lutz-Kutschera, G.; Robien, W.; Greger, H.; Hofer, O. Phytochemistry 2009, 70, 1030-1037
9. Yahayu, M. A.; Rahmani, M.; Hashim, N. M.; Amin, M. A. M.; Ee, G. C. L.; Sukari, M. A.; Akim, A. M. Molecules 2011, 16, 4401-4407
10. Wu, T.-S.; Furukawa, H.; Kuoh, C.-S.; Hsu, K.-S. J. Chem. Soc., Perkin Trans. 1 1983, 1681-1688
11. Quader, M. A.; Nutan, M. T. H.; Rashid, M. A. Fitoterapia 1999, 70, 305-307
12. Ono, T.; Ito, C.; Furukawa, H.; Wu, T.-S.; Kuoh, C.-S.; Hsu, K.-S. J. Nat. Prod. 1995, 58, 1629-1631
13. Yang, G.-Z.; Wu, Y.; Chen, Y. Helv. Chim. Acta 2012, 95, 1449-1454
14. Ito, C.; Itoigawa, M.; Sato, A.; Hasan, C. M.; Rashid, M. A.; Tokuda, H.; Mukainaka, T.; Nishino, H.; Furukawa, H. J. Nat. Prod. 2004, 67, 1488-1491
15. Bhattacharyya, P.; Chowdhury, B. K. J. Nat. Prod. 1985, 48, 465-466
16. Bhattacharyya, P.; Chowdhury, B. K. Phytochemistry 1985, 24, 634-635
17. Sarkar, M.; Chakraborty, D. P. Phytochemistry 1977, 16, 2007-2008
18. Hofer, O.; Greger, H.; Lukaseder, B.; Vajrodaya, S.; Bacher, M. Phytochemistry 2000, 54, 207-213
19. Greger, H.; Zechner, G.; Hofer, O.; Vajrodaya, S. J. Nat. Prod. 1996, 59, 1163-1168
20. Greger, H.; Zechner, G.; Hofer, O.; Hadacek, F.; Wurz, G. Phytochemistry 1993, 34, 175-179
21. Greger, H.; Hadacek, F.; Hofer, O.; Wurz, G.; Zechner, G. Phytochemistry 1993, 32, 933-936
22. Basa, S. C. Experientia 1975, 31, 1387
23. Brown, R.; Lahey, F. Aust. J. Chem. 1950, 3, 593-614
24. Göckler, N.; Jofre, G.; Papadopoulos, C.; Soppa, U.; Tejedor, F. J.; Becker, W. FEBS J. 2009, 276, 6324-6337
25. Tahtouh, T.; Elkins, J. M.; Filippakopoulos, P.; Soundararajan, M.; Burgy, G.; Durieu, E.; Cochet, C.; Schmid, R. S.; Lo, D. C.; Delhommel, F.; Oberholzer, A. E.; Pearl, L. H.; Carreaux, F.; Bazureau, J. P.; Knapp, S.; Meijer, L. J. Med. Chem. 2012, 55, 9312-9330
26. Debdab, M.; Renault, S.; Soundararajan, M.; Fedorov, O.; Filippakopoulos, P.; Lozach, O.; Babault, L.; Tahtouh, T.; Baratte, B.; Ogawa, Y.; Hagiwara, M.; Eisenreich, A.; Rauch, U.; Knapp, S.; Meijer, L.; Bazureau, J.-P. J. Med. Chem. 2011, 54, 4172-4186
27. Leclerc, S.; Garnier, M.; Hoessel, R.; Marko, D.; Gretchen, B.; Snyder, P.; Greengard, P.; Biernat, J.; Wu, Y.-Z.; Mandelkow, E.-M.; Eisenbrand, G.; Meijer, L. J. Biol. Chem. 2001, 276, 251-260
28. Bach, S.; Knockaert, M.; Reinhardt, J.; Lozach, O.; Schmitt, S.; Baratte, B.; Koken, M.; Coburn, S. P.; Tang, L.; Jiang, T.; Liang, D. C.; Galons, H.; Dierick, J. F.; Pina, L. A.; Meggio, F.; Totzke, F.; Schachtele, C.; Lerman, A. S.; Carnero, A.; Wan, Y.; Gray, N.; Meijer, L. J. Biol. Chem. 2005, 280, 31208-31219
29. Primot, A.; Baratte, B.; Gompel, M.; Borgne, A.; Liabeuf, S.; Romette, J. L.; Costantini, F.; Meijer, L. Protein Expr. Purif. 2000, 20, 394-404
30. Beauchard, A.; Ferandin, Y.; Frère, S.; Lozach, O.; Blairvacq, M.; Meijer, L.; Thiéry, V.; Besson, T. Bioorg. Med. Chem. 2006, 14, 6434-6443
31. Reinhardt, J.; Ferandin, Y.; Meijer, L. Protein Expr. Purif. 2007, 54, 101-109
32. Larkin, M. A.; Blackshields, G.; Brown, N. P.; Chenna, R.; McGettigan, P. A.; McWilliam, H.; Valentin, F.; Wallace, I. M.; Wilm, A.; Lopez, R.; Thompson, J. D.; Gibson, T. J.; Higgins, D. G. Bioinformatics 2007, 23, 2947-2948
33. Verdonk, M. L.; Cole, J. C.; Hartshorn, M. J.; Murray, C. W.; Taylor, R. D. Proteins 2003, 52, 609-623
34. Ogawa, Y.; Nonaka, Y.; Goto, T.; Ohnishi, E.; Hiramatsu, T.; Kii, I.; Yoshida, M.; Ikura, T.; Onogi, H.; Shibuya, H.; Hosoya, T.; Ito, N.; Hagiwara, M. Nat. Commun. 2010, 1, 1-9