Double heterozygotes among breast cancer patients analyzed for BRCA1, CHEK2, ATM, NBN/NBS1, and BLM germ-line mutations

Breast Cancer Research and Treatment

Volumn 145, Issue 2, 2014, Pages 553-562

  Sokolenko, Anna P ^a,b   Bogdanova, Natalia ^c   Kluzniak, Wojciech ^d   Preobrazhenskaya, Elena V ^a   Kuligina, Ekatherina S ^a   Iyevleva, Aglaya G ^a,b   Aleksakhina, Svetlana N ^a   Mitiushkina, Natalia V ^a   Gorodnova, Tatiana V ^a   Bessonov, Alexandr A ^e   Togo, Alexandr V ^a,b   Lubiński, Jan ^d   Cybulski, Cezary ^d   Jakubowska, Anna ^d   Dörk, Thilo ^c   Imyanitov, Evgeny N ^a,b,f  

^a N N PETROV RESEARCH INSTITUTE OF ONCOLOGY   (Russian Federation)

^b SAINT PETERSBURG STATE PEDIATRIC MEDICAL UNIVERSITY   (Russian Federation)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d POMERANIAN MEDICAL UNIVERSITY   (Poland)

^e St Petersburg City Oncology Center   (Russian Federation)

^f NORTH WESTERN STATE MEDICAL UNIVERSITY NAMED AFTER I I MECHNIKOV   (Russian Federation)

Author keywords

Breast cancer; Double heterozygote; Gene interactions; Germ line mutations; Review

Indexed keywords

ATM PROTEIN; BLOOM SYNDROME HELICASE; CHECKPOINT KINASE 2; NIBRIN; ATM PROTEIN, HUMAN; BRCA1 PROTEIN; BRCA1 PROTEIN, HUMAN; CELL CYCLE PROTEIN; CHEK2 PROTEIN, HUMAN; NBN PROTEIN, HUMAN; NUCLEAR PROTEIN; RECQ HELICASE;

ADULT; ALLELE; ARTICLE; ATM GENE; BLM GENE; BREAST CANCER; CHEK2 GENE; CLINICAL ARTICLE; CONTROLLED STUDY; DOUBLE HETEROZYGOTE; FEMALE; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GERMLINE MUTATION; HETEROZYGOSITY LOSS; HETEROZYGOTE; HETEROZYGOTE DETECTION; HUMAN; MIDDLE AGED; MUTATIONAL ANALYSIS; NIBRIN GENE; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE; BELARUS; BREAST TUMOR; CASE CONTROL STUDY; FOUNDER EFFECT; GENETIC PREDISPOSITION; GENETICS; POLAND; RUSSIAN FEDERATION;

ADULT; ATAXIA TELANGIECTASIA MUTATED PROTEINS; BRCA1 PROTEIN; BREAST NEOPLASMS; CASE-CONTROL STUDIES; CELL CYCLE PROTEINS; CHECKPOINT KINASE 2; FEMALE; FOUNDER EFFECT; GENETIC PREDISPOSITION TO DISEASE; GERM-LINE MUTATION; HETEROZYGOTE; HUMANS; LOSS OF HETEROZYGOSITY; MIDDLE AGED; NUCLEAR PROTEINS; POLAND; RECQ HELICASES; REPUBLIC OF BELARUS; RUSSIA;

EID: 84901653149     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-014-2971-1     Document Type: Article

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