Comparison between the ICRU rectal point and modern volumetric parameters in brachytherapy for locally advanced cervical cancer

Cancer/Radiotherapie

Volumn 18, Issue 3, 2014, Pages 177-182

  Mazeron, R ^a,b   Kamsu Kom, L ^a   Rivin del Campo, E ^a   Dumas, I ^a   Farha, G ^a   Champoudry, J ^a   Chargari, C ^a   Martinetti, F ^a   Lefkopoulos, D ^a,b   Haie Meder, C ^a  

^a INSTITUT GUSTAVE ROUSSY   (France)

^b Institut Gustave Roussy   (France)

Author keywords

Brachytherapy; Cervical cancer; ICRU point; Rectum

Indexed keywords

ADVANCED CANCER; ARTICLE; BRACHYTHERAPY; COMPARATIVE STUDY; DOSIMETRY; EXTERNAL BEAM RADIOTHERAPY; FEMALE; HUMAN; INTERNATIONAL COMMISSION ON RADIATION UNITS AND MEASUREMENT RECTAL POINT; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RADIATION DOSE; RADIOLOGICAL PARAMETERS; RECTUM; UTERINE CERVIX CANCER;

BRACHYTHERAPY; CANCER DU COL UTÉRIN; CERVICAL CANCER; CURIETHÉRAPIE; ICRU POINT; POINT DE L'ICRU; RECTUM;

BRACHYTHERAPY; FEMALE; HUMANS; IMAGING, THREE-DIMENSIONAL; LINEAR MODELS; MAGNETIC RESONANCE IMAGING, INTERVENTIONAL; ORGANS AT RISK; PROSPECTIVE STUDIES; RADIOGRAPHY, INTERVENTIONAL; RADIOTHERAPY DOSAGE; RADIOTHERAPY, IMAGE-GUIDED; RECTUM; UTERINE CERVICAL NEOPLASMS;

EID: 84901631591     PISSN: 12783218     EISSN: 17696658     Source Type: Journal    
DOI: 10.1016/j.canrad.2014.03.002     Document Type: Article

References (28)

1. Nomden C.N., de Leeuw A.A., Roesink J.M., Tersteeg R.J., Moerland M.A., Witteveen P.O., et al. Clinical outcome and dosimetric parameters of chemo-radiation including MRI guided adaptive brachytherapy with tandem-ovoid applicators for cervical cancer patients: a single institution experience. Radiother Oncol 2013, 107:69-74.
2. Mazeron R., Gilmore J., Dumas I., Champoudry J., Goulart J., Vanneste B., et al. Adaptive 3D image-guided brachytherapy: a strong argument in the debate on systematic radical hysterectomy for locally advanced cervical cancer. Oncologist 2013, 18:415-422.
3. Charra-Brunaud C., Harter V., Delannes M., Haie-Meder C., Quetin P., Kerr C., et al. Impact of 3D image-based PDR brachytherapy on outcome of patients treated for cervix carcinoma in France: results of the French STIC prospective study. Radiother Oncol 2012, 103:305-313.
4. Potter R., Georg P., Dimopoulos J.C., Grimm M., Berger D., Nesvacil N., et al. Clinical outcome of protocol based image (MRI) guided adaptive brachytherapy combined with 3D conformal radiotherapy with or without chemotherapy in patients with locally advanced cervical cancer. Radiother Oncol 2011, 100:116-123.
5. Haie-Meder C., Thomas L., Barillot I., Pommier P., Nickers P. [Image-guided adaptive brachytherapy in the treatment of patients with cervix cancer]. Cancer Radiother 2013, 17:98-105.
6. Dumas I., Champoudry J., Martinetti F., Haie-Meder C., Bossi A., Lefkopoulos D. [Contribution of 3D imaging in brachytherapy: which kind of imaging for which localization?]. Cancer Radiother 2013, 17:93-97.
7. Gnep K., Mazeron R. [Radiotherapy for cervix carcinomas: clinical target volume delineation]. Cancer Radiother 2013, 17:486-492.
8. Haie-Meder C., Potter R., Van Limbergen E., Briot E., De Brabandere M., Dimopoulos J., et al. Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group (I): concepts and terms in 3D image based 3D treatment planning in cervix cancer brachytherapy with emphasis on MRI assessment of GTV and CTV. Radiother Oncol 2005, 74:235-245.
9. Potter R., Haie-Meder C., Van Limbergen E., Barillot I., De Brabandere M., Dimopoulos J., et al. Recommendations from gynaecological (GYN) GEC ESTRO working group (II): concepts and terms in 3D image-based treatment planning in cervix cancer brachytherapy-3D dose-volume parameters and aspects of 3D image-based anatomy, radiation physics, radiobiology. Radiother Oncol 2006, 78:67-77.
10. Albano M., Dumas I., Haie-Meder C. [Brachytherapy at the Institut Gustave-Roussy: personalized vaginal mould applicator: technical modification and improvement]. Cancer Radiother 2008, 12:822-826.
11. Barillot I., Horiot J.C., Maingon P., Bone-Lepinoy M.C., Vaillant D., Feutray S. Maximum and mean bladder dose defined from ultrasonography. Comparison with the ICRU reference in gynaecological brachytherapy. Radiother Oncol 1994, 30:231-238.
12. Kirisits C., Lang S., Dimopoulos J., Berger D., Georg D., Potter R. The Vienna applicator for combined intracavitary and interstitial brachytherapy of cervical cancer: design, application, treatment planning, and dosimetric results. Int J Radiat Oncol Biol Phys 2006, 65:624-630.
13. Kirisits C., Potter R., Lang S., Dimopoulos J., Wachter-Gerstner N., Georg D. Dose and volume parameters for MRI-based treatment planning in intracavitary brachytherapy for cervical cancer. Int J Radiat Oncol Biol Phys 2005, 62:901-911.
14. Mazeron R., Gilmore J., Champoudry J., Dumas I., Helou J., Maroun P., et al. Volumetric evaluation of an alternative bladder point in brachytherapy for locally advanced cervical cancer. Strahlenther Onkol 2014, 190:41-47.
15. Ling C.C., Schell M.C., Working K.R., Jentzsch K., Harisiadis L., Carabell S., et al. CT-assisted assessment of bladder and rectum dose in gynecological implants. Int J Radiat Oncol Biol Phys 1987, 13:1577-1582.
16. Schoeppel S.L., LaVigne M.L., Martel M.K., McShan D.L., Fraass B.A., Roberts J.A. Three-dimensional treatment planning of intracavitary gynecologic implants: analysis of ten cases and implications for dose specification. Int J Radiat Oncol Biol Phys 1994, 28:277-283.
17. van den Bergh F., Meertens H., Moonen L., van Bunningen B., Blom A. The use of a transverse CT image for the estimation of the dose given to the rectum in intracavitary brachytherapy for carcinoma of the cervix. Radiother Oncol 1998, 47:85-90.
18. Perez C.A., Grigsby P.W., Lockett M.A., Chao K.S., Williamson J. Radiation therapy morbidity in carcinoma of the uterine cervix: dosimetric and clinical correlation. Int J Radiat Oncol Biol Phys 1999, 44:855-866.
19. Wachter-Gerstner N., Wachter S., Reinstadler E., Fellner C., Knocke T.H., Wambersie A., et al. Bladder and rectum dose defined from MRI based treatment planning for cervix cancer brachytherapy: comparison of dose-volume histograms for organ contours and organ wall, comparison with ICRU rectum and bladder reference point. Radiother Oncol 2003, 68:269-276.
20. Inn Tan Y., Ai Choo B., Mun Laa K. 2D to 3D evaluation of organs at risk doses in intracavitary brachtherapy for cervical cancer. J Contemp Brachyther 2010, 2:37-43.
21. Pelloski C.E., Palmer M., Chronowski G.M., Jhingran A., Horton J., Eifel P.J. Comparison between CT-based volumetric calculations and ICRU reference-point estimates of radiation doses delivered to bladder and rectum during intracavitary radiotherapy for cervical cancer. Int J Radiat Oncol Biol Phys 2005, 62:131-137.
22. Vinod S.K., Caldwell K., Lau A., Fowler A.R. A comparison of ICRU point doses and volumetric doses of organs at risk (OARs) in brachytherapy for cervical cancer. J Med Imaging Radiat Oncol 2011, 55:304-310.
23. Yaparpalvi R., Mutyala S., Gorla G.R., Butler J., Mah D., Garg M.K., et al. Point vs volumetric bladder and rectal doses in combined intracavitary-interstitial high-dose-rate brachytherapy: correlation and comparison with published Vienna applicator data. Brachytherapy 2008, 7:336-342.
24. Koom W.S., Sohn D.K., Kim J.Y., Kim J.W., Shin K.H., Yoon S.M., et al. Computed tomography-based high-dose-rate intracavitary brachytherapy for uterine cervical cancer: preliminary demonstration of correlation between dose-volume parameters and rectal mucosal changes observed by flexible sigmoidoscopy. Int J Radiat Oncol Biol Phys 2007, 68:1446-1454.
25. Georg P., Kirisits C., Goldner G., Dorr W., Hammer J., Potzi R., et al. Correlation of dose-volume parameters, endoscopic and clinical rectal side effects in cervix cancer patients treated with definitive radiotherapy including MRI-based brachytherapy. Radiother Oncol 2009, 91:173-180.
26. Georg P., Potter R., Georg D., Lang S., Dimopoulos J.C., Sturdza A.E., et al. Dose effect relationship for late side effects of the rectum and urinary bladder in magnetic resonance image-guided adaptive cervix cancer brachytherapy. Int J Radiat Oncol Biol Phys 2011, 82:653-657.
27. Levitchi M., Charra-Brunaud C., Quetin P., Haie-Meder C., Kerr C., Castelain B., et al. Impact of dosimetric and clinical parameters on clinical side effects in cervix cancer patients treated with 3D pulse-dose-rate intracavitary brachytherapy. Radiother Oncol 2012, 103:314-321.
28. embracestudy.dk [homepage on the Internet]. EMBRACE, an international study on Mri-guided brachytherapy in locally advanced cervical cancer. Vienna: Medical University of Vienna. URL: [accessed 04/01/2014]. https://www.embracestudy.dk/About.aspx.