Correlation of dose-volume parameters, endoscopic and clinical rectal side effects in cervix cancer patients treated with definitive radiotherapy including MRI-based brachytherapy

Radiotherapy and Oncology

Volumn 91, Issue 2, 2009, Pages 173-180

  Georg, Petra ^a   Kirisits, Christian ^a   Goldner, Gregor ^a   Dörr, Wolfgang ^b   Hammer, Johann ^a   Pötzi, Regina ^a   Berger, Daniel ^a   Dimopoulos, Johannes ^a   Georg, Dietmar ^a   Pötter, Richard ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Brachytherapy; Cervix cancer; DVH parameters; Rectoscopy; Side effects

Indexed keywords

CISPLATIN; CORTICOSTEROID;

ADULT; AGED; ANEMIA; ARTICLE; BRACHYTHERAPY; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CLINICAL ARTICLE; CONTROLLED STUDY; DIARRHEA; DOSIMETRY; EXTERNAL BEAM RADIOTHERAPY; FEMALE; FOLLOW UP; HUMAN; INTESTINE NECROSIS; MORBIDITY; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RADIATION NECROSIS; RECTOVAGINAL FISTULA; RECTUM HEMORRHAGE; RECTUM ULCER; SIGMOIDOSCOPY; TELANGIECTASIA; UTERINE CERVIX CANCER;

ADULT; AGED; AGED, 80 AND OVER; BRACHYTHERAPY; DOSE-RESPONSE RELATIONSHIP, RADIATION; ENDOSCOPY; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MIDDLE AGED; RADIOTHERAPY DOSAGE; UTERINE CERVICAL NEOPLASMS;

EID: 65449169120     PISSN: 01678140     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.radonc.2009.01.006     Document Type: Article

References (48)

1. Barillot I., Horiot J.C., Maingon P., et al. Impact on treatment outcome and late effects of customized treatment planning in cervix carcinomas: baseline results to compare new strategies. Int J Radiat Oncol Biol Phys 48 (2000) 189-200
2. Chargari C., Magne N., Dumas I., et al. Physics contributions and clinical outcome with 3D-MRI-based pulsed-dose-rate intracavitary brachytherapy in cervical cancer patients. Int J Radiat Oncol Biol Phys 74 (2009) 133-139
3. Chi K.D., Ehrenpreis E.D., and Jani A.B. Accuracy and reliability of the endoscopic classification of chronic radiation induced proctopathy using a novel grading method. J Clin Gastroenterol 39 (2005) 42-45
4. Chen S.W., Liang J.A., Yang S.N., et al. The prediction of late rectal complications following the treatment of uterine cervical cancer by high-dose-rate brachytherapy. Int J Radiat Oncol Biol Phys 47 (2000) 955-961
5. Chun M., Kang S., Kil H.J., et al. Rectal bleeding and its management after irradiation for uterine cervix cancer. Int J Radiat Oncol Biol Phys 58 (2004) 98-105
6. Clark B.G., Souhami L., Roman T.N., et al. The prediction of late rectal complications in patients treated with high dose-rate brachytherapy for carcinoma of the cervix. Int J Radiat Oncol Biol Phys 38 (1997) 989-993
7. Davidson S.E., Burns M.P., Routledge J.A., et al. Assessment of morbidity in carcinoma of the cervix: a comparison of the LENT SOMA scales and Franco-Italian glossary. Radiother Oncol 69 (2003) 195-200
8. De Brabandere M., Mousa A.G., Nulens A., et al. Potential of dose optimisation in MRI-based PDR brachytherapy of cervix carcinoma. Radiother Oncol 88 (2008) 217-226
9. Dimopoulos J.C.A., Schard G., Berger D., et al. Systematic evaluation of MRI findings in different stages of treatment of cervical cancer: potential of MRI on delineation of target, pathoanatomic structures, and organs at risk. Int J Radiat Oncol Biol Phys 64 (2006) 1380-1388
10. Dimopoulos J.C., Kirisists C., Petric P., et al. The Vienna applicator for combined intracavitary and interstitial barchytherapy of cervical cancer: clinical feasibility and preliminary results. Int J Radiat Oncol Biol Phys 66 (2006) 83-90
11. Eifel P.J., Thoms W.W.J., Smith T.L., et al. The relationship between brachytherapy dose and outcome in patients with bulky endocervical tumors treated with radiation alone. Int J Radiat Oncol Biol Phys 28 (1994) 113-118
12. Eifel P.J., Levenback C., Wharton T., and Oswald M.J. Time course and incidence of late complications in patients treated with radiation therapy for Figo stage Ib carcinoma of the uterine cervix. Int J Radiat Oncol Biol Phys 32 (1995) 1289-1300
13. Erickson B. The sculpted pear: an unfinished brachytherapy tale. Brachytherapy 2 (2003) 189-199
14. Erickson B., Grossheim L., Mai J., et al. Imaging the non-displaced rectosigmoid during HDR brachytherapy for cervical cancer can alter dose specification. Radiother Oncol 71 Suppl. 2 (2004) S9
15. Fransson A., Andreo P., and Pötter R. Aspects of MR image distortions in radiotherapy treatment planning. Strahlenther Onkol 177 (2001) 59-73
16. Fowler J.F. The linear-quadratic formula and progress in fractionated radiotherapy. Br J Radiol 62 (1989) 679-694
17. Gerbaulet A, Pötter R, Haie-Meder C. Cervix Cancer. In: Gerbaulet et al. editors. GEC ESTRO handbook of brachytherapy, ESTRO Brussels; 2002. p. 301-363.
18. Goldner G., Tomicek B., Becker G., et al. Proctitis after external beam radiotherapy for prostate cancer classified by the "Vienna Rectoscopy Score" and correlated to the EORTC/RTOG Score for late rectal toxicity: results of a prospective multicenter study in 166 patients. Int J Radiat Oncol Biol Phys 67 (2007) 78-83
19. Haie-Meder C., Pötter R., van Limbergen E., et al. Recommendations from the Gynaecological (GYN) GEC ESTRO Working Group: concepts and terms in 3D image based 3D treatment planning in cervix cancer brachytherapy with emphasis on MRI assessment of GTV and CTV. Radiother Oncol 74 (2005) 235-245
20. ICRU, International Commission of Radiation Units and Measurements. Dose and volume specification for reporting intracavitary therapy in gynaecology, ICRU Report 38, 1985, Bethesda, MD.
21. Joiner M.C., and Bentzen S.M. Time-dose relationships: the linear-quadratic approach. In: Steel G.G. (Ed). Basic clinical radiobiology. 3rd ed. (2002), Arnold, London 120-133
22. Kapp K.S., Stuecklschweiger G.F., Kapp D.S., et al. Carcinoma of the cervix: analysis of complications after primary external beam radiation and Ir-192 HDR brachytherapy. Radiother Oncol 42 (1997) 143-153
23. Kim R.Y., and Pareek P. Radiography-based treatment planning compared with computed tomography (CT)-based treatment planning for intracavitary brachytherapy in cancer of the cervix: analysis of dose-volume histograms. Brachytherapy 2 (2003) 200-206
24. Kim T.H., Choi J., Park S.Y., et al. Dosimetric parameters that predict late rectal complications after curative radiotherapy in patients with uterine cervical carcinoma. Cancer 104 (2005) 1304-1311
25. Kirisits C., Pötter R., Lang S., et al. Dose and volume parameters for MRI-based treatment planning in intracavitary brachytherapy for cervical cancer. Int J Radiat Oncol Biol Phys 62 (2005) 901-911
26. Koom W.S., Sohn D.Y., Kim J.Y., et al. Treatment planning for MRI assisted brachytherapy of gynecologic malignancies based on total dose constraints. Int J Radiat Oncol Biol Phys 68 (2007) 1446-1454
27. Lang S., Kirisits C., Dimopoulos J., Georg D., and Pötter R. Treatment planning for MRI assisted brachytherapy of gynecologic malignancies based on total dose constraints. Int J Radiat Oncol Biol Phys 69 (2007) 619-627
28. LENT SOMA tables. Int J Radiat Oncol Biol Phys 1995;31:1048-1092.
29. Lindegaard J.C., Tanderup K., Nielsen S.K., Haack S., and Gelineck J. MRI-guided 3D optimization significantly improves DVH parameters of pulsed-dose-rate brachytherapy in locally advanced cervical cancer. Int J Radiat Oncol Biol Phys 71 (2008) 756-764
30. Nag S., Erickson B., Thomadsen B., et al. The American Brachytherapy Society recommendations for high-dose-rate brachytherapy for carcinoma of the cervix. Int J Radiat Oncol Biol Phys 48 (2000) 201-211
31. Nag S., Cardenes H., Chang S., et al. Proposed quidelines for image-based intracavitary brachytherapy for cervical carcinoma: report from Image-Guided Brachytherapy Working Group. Int J Radiat Oncol Biol Phys 60 (2004) 1160-1172
32. O'Brien P.C., Hamilton C.S., Denham J.W., et al. Spontaneous improvement in late rectal mucosal changes after radiotherapy for prostate cancer. Int J Radiat Oncol Biol Phys 58 (2004) 75-80
33. Olszewska A.M., Saarnak A.E., de Boer R.W., et al. Comparison of dose volume histograms and dose-wall histograms of the rectum of patients treated with intracavitary brachytherapy. Radiother Oncol 61 (2001) 83-85
34. Pelloski C.E., Palmer M., Chronowski G.M., et al. Comparison between CT-based volumetric calculations and ICRU reference-point estimates of radiation doses delivered to bladder and rectum during intracavitary radiotherapy for cervical cancer. Int J Radiat Oncol Biol Phys 62 (2005) 131-137
35. Perez C.A., Grigsby P.E., Lockett M.A., et al. Radiation therapy morbidity in carcinoma of the uterine cervix: dosimetric and clinical correlation. Int J Radiat Oncol Biol Phys 44 (1999) 855-866
36. Pötter R., Knocke T.H., Fellner C., Baldass M., Reinthaller A., and Kucera H. Definitive radiotherapy based on HDR brachytherapy with iridium 192 in uterine cervix carcinoma: report on the Vienna University Hospital findings (1993-1997) compared to the preceding period in the context of ICRU 38 recommendations. Cancer Radiother 4 (2000) 159-172
37. Pötter R., Haie-Meder C., van Limbergen E., et al. Recommendations from gynaecological (GYN) GEC ESTRO working group (II): concepts and terms in 3D image-based treatment planning in cervix cancer brachytherapy-3D dose volume parameters and aspects of 3D image-based anatomy, radiation physics, radiobiology. Radiother Oncol 78 (2006) 67-77
38. Pötter R., Dimopoulos J., Bachtiary B., et al. 3D conformal HDR-brachy- and external beam therapy plus simultaneous cisplatin for high-risk cervical cancer: clinical experience with 3 year follow-up. Radiother Oncol 79 (2006) 80-86
39. Pötter R., Dimopoulos J., Georg P., et al. Clinical impact of MRI assisted dose volume adaptation and dose escalation in brachytherapy of locally advanced cervix cancer. Radiother Oncol 83 (2007) 148-155
40. Pourquier H., Dubois J.B., and Delard R. Cancer of the uterine cervix: dosimetric guidelines for prevention of late rectal and rectosigmoid complications as a result of radiotherapeutic treatment. Int J Radiat Oncol Biol Phys 8 (1982) 1887-1895
41. Routledge J.A., Burns M.P., Swindell R., et al. Evaluation of the LENT-SOMA scales for the prospective assessment of treatment morbidity in cervical carcinoma. Int J Radiat Oncol Biol Phys 56 (2003) 502-510
42. Sakata K.I., Nagakura H., Oouchi A., et al. High-dose-rate intracavitary brachytherapy: results of analyses of late rectal complications. Int J Radiat Oncol Biol Phys 54 (2002) 1369-1376
43. van den Bergh F., Meertens H., Moonen L.M.F., et al. The use of a transverse CT image for the estimation of the dose given to the rectum in intracavitary brachytherapy for carcinoma of the cervix. Radiother Oncol 47 (1998) 85-90
44. Viswanathan A.N., Dimopoulos J., Kirisits C., et al. Computed tomography versus magnetic resonance imaging-based contouring in cervical cancer brachytherapy: results of a prospective trial and preliminary guidelines for standardized contours. Int J Radiat Oncol Biol Phys 68 (2007) 491-498
45. Wachter S., Gerstner N., Goldner G., et al. Endoscopic scoring of late rectal mucosal damage after conformal radiotherapy for prostatic carcinoma. Radiother Oncol 54 (2000) 11-19
46. Wachter-Gerstner N., Wachter S., Reinstadler E., et al. The impact of sectional imaging on dose escalation in endocavitary HDR-brachytherapy of cervical cancer: results of prospective comparative trial. Radiother Oncol 68 (2003) 51-59
47. Wachter-Gerstner N., Wachter S., Reinstadler E., et al. Bladder and rectum dose defined from MRI based treatment planning for cervix cancer brachytherapy: comparison of dose-volume histograms for organ contours and organ wall, comparison with ICRU rectum and bladder reference point. Radiother Oncol 68 (2003) 269-276
48. Wang C.J., Leung S.W., Chen H.C., et al. High-dose-rate intracavitary brachytherapy (HDR-IC) in treatment of cervical carcinoma: 5-year results and implication of increased low-grade rectal complication on initiation of an HDR-IC fractionation scheme. Int J Radiat Oncol Biol Phys 38 (1997) 391-398