Antagonism of Sorafenib and Regorafenib actions by platelet factors in hepatocellular carcinoma cell lines

BMC Cancer

Volumn 14, Issue 1, 2014, Pages

  D'Alessandro, Rosalba ^a   Refolo, Maria G ^a   Lippolis, Catia ^a   Giannuzzi, Grazia ^b   Carella, Nicola ^a   Messa, Caterina ^a   Cavallini, Aldo ^a   Carr, Brian I ^a  

^a NATIONAL INSTITUTE FOR DIGESTIVE DISEASES   (Italy)

^b S Maria degli Angeli Hospital   (Italy)

Author keywords

Apoptosis; Growth; HCC; Invasion; Platelets; Regorefenib

Indexed keywords

EPIDERMAL GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BAX; PROTEIN BCL XL; REGORAFENIB; SOMATOMEDIN C; SORAFENIB; STAT3 PROTEIN; ANTINEOPLASTIC AGENT; APOPTOSIS REGULATORY PROTEIN; CARBANILAMIDE DERIVATIVE; IGF1 PROTEIN, HUMAN; NICOTINAMIDE; PROTEIN KINASE INHIBITOR; PYRIDINE DERIVATIVE;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL INVASION; CELL LYSATE; CONTROLLED STUDY; HEPATOCELLULAR CARCINOMA CELL LINE; HUMAN; HUMAN CELL; MIGRATION INHIBITION; PLATELET LYSATE; SIGNAL TRANSDUCTION; THROMBOCYTE; ANALOGS AND DERIVATIVES; BLOOD; CELL MOTION; CELL PROLIFERATION; DRUG EFFECTS; ENZYME ACTIVATION; HEPG2 CELL LINE; LIVER CELL CARCINOMA; LIVER TUMOR; METABOLISM; PATHOLOGY; PHOSPHORYLATION; TIME; TUMOR INVASION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BLOOD PLATELETS; CARCINOMA, HEPATOCELLULAR; CELL MOVEMENT; CELL PROLIFERATION; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HEP G2 CELLS; HUMANS; INSULIN-LIKE GROWTH FACTOR I; LIVER NEOPLASMS; NEOPLASM INVASIVENESS; NIACINAMIDE; PHENYLUREA COMPOUNDS; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PYRIDINES; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84901611471     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-14-351     Document Type: Article

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