Characterization of fenofibrate-mediated anti-proliferative pro-apoptotic effects on high-grade gliomas and anti-invasive effects on glioma stem cells

Journal of Neuro-Oncology

Volumn 117, Issue 2, 2014, Pages 225-234

  Binello, Emanuela ^a   Mormone, Elisabetta ^a   Emdad, Luni ^a   Kothari, Harini ^a   Germano, Isabelle M ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Fenofibrate; Glioma; Glioma stem cells; Invasion; PPAR ; Proliferation

Indexed keywords

CD133 ANTIGEN; CYCLIN D1; FENOFIBRATE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PROTEIN BAX; PROTEIN BCL XL; PROTEIN KINASE B; PROTEIN P53; ANTINEOPLASTIC AGENT;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DOSE RESPONSE; GLIOBLASTOMA; GLIOBLASTOMA CELL LINE; GLIOMA; GLIOMA CELL; HUMAN; HUMAN CELL; MEDULLOBLASTOMA; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR INVASION; TUMOR MICROENVIRONMENT; ANTAGONISTS AND INHIBITORS; CANCER GRADING; CANCER STEM CELL; CYTOLOGY; DRUG EFFECTS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; METABOLISM; PATHOLOGY; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CELL PROLIFERATION; FENOFIBRATE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GLIOMA; HUMANS; NEOPLASM GRADING; NEOPLASM INVASIVENESS; NEOPLASTIC STEM CELLS; PPAR ALPHA;

EID: 84901609954     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-014-1385-6     Document Type: Article

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