Inactivation of PI3K/AKT signaling inhibits glioma cell growth through modulation of β-catenin-mediated transcription

Brain Research

Volumn 1366, Issue , 2010, Pages 9-17

  Han, Lei ^a   Yang, Yang ^a   Yue, Xiao ^a,b   Huang, Kai ^a,b   Liu, Xiaomin ^b   Pu, Peiyu ^a   Jiang, Hao ^c   Yan, Wei ^d   Jiang, Tao ^d   Kang, Chunsheng ^a  

^a GENERAL HOSPITAL OF NORTHERN THEATER COMMAND   (China)

^b TIANJIN MEDICAL UNIVERSITY   (China)

^c HENRY FORD HOSPITAL   (United States)

^d CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Catenin; AKT; Glioma; PI3K inhibitor; Signaling pathway

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; BETA CATENIN; CYCLIN D1; MYC PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR FRA 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; DOWN REGULATION; DRUG MECHANISM; FEMALE; GLIOBLASTOMA; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR XENOGRAFT;

ANIMALS; BETA CATENIN; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMONES; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; FEMALE; GENE EXPRESSION REGULATION; GLIOMA; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; MORPHOLINES; ONCOGENE PROTEIN V-AKT; PHOSPHATIDYLINOSITOL 3-KINASES; SERINE; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION;

MUS MUSCULUS;

EID: 79251624612     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2010.09.097     Document Type: Article

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