Calcineurin downregulation in the amygdala is sufficient to induce anxiety-like and depression-like behaviors in C57BL/6J male mice

Biological Psychiatry

Volumn 75, Issue 12, 2014, Pages 991-998

  Mineur, Yann S ^a   Taylor, Seth R ^a   Picciotto, Marina R ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

AAV; anxiety; calcineurin; cyclosporine A; depression; elevated plus maze; forced swim; PP2B; shRNA; tail suspension

Indexed keywords

CALCINEURIN; CYCLOSPORIN A; SHORT HAIRPIN RNA; CALCINEURIN INHIBITOR; CYCLOSPORIN; SMALL INTERFERING RNA;

ADENO ASSOCIATED VIRUS; ADENOVIRUS; AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; BRAIN; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DEPRESSION; FORCED SWIM TEST; GENE TRANSFER; GRAFT REJECTION; IMMOBILITY; LIGHT DARK CYCLE; LOCOMOTION; MALE; MAZE TEST; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; ANIMAL BEHAVIOR; BIOSYNTHESIS; C57BL MOUSE; CHEMICALLY INDUCED; COMPLICATION; DOWN REGULATION; DRUG EFFECTS; METABOLISM; MICROINJECTION;

AMYGDALA; ANIMALS; ANXIETY; BEHAVIOR, ANIMAL; CALCINEURIN; CALCINEURIN INHIBITORS; CYCLOSPORINE; DEPRESSION; DOWN-REGULATION; MALE; MICE; MICE, INBRED C57BL; MICROINJECTIONS; RNA, SMALL INTERFERING;

EID: 84901483980     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2014.03.009     Document Type: Article

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