메뉴 건너뛰기




Volumn 58, Issue 3, 2014, Pages 251-259

Hypercholesterolemic diet induces hepatic steatosis and alterations in mRNA expression of NADPH oxidase in rat livers;Dieta hipercolesterolemiante induz esteatose hepática e alterações na expressão de mRNA da NADPH oxidase em fígados de ratos

Author keywords

Antioxidant enzymes; Hepatic steatosis; Hypercholesterolemic diet; NADPH oxidase; Non alcoholic fatty liver disease; Oxida tive stress

Indexed keywords

ALANINE AMINOTRANSFERASE; ANTIOXIDANT; ASPARTATE AMINOTRANSFERASE; CATALASE; CHOLESTEROL; CHOLESTEROL INTAKE; GLUTATHIONE; LIPID; MESSENGER RNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL;

EID: 84901481057     PISSN: 00042730     EISSN: 16779487     Source Type: Journal    
DOI: 10.1590/0004-2730000002831     Document Type: Article
Times cited : (23)

References (40)
  • 1
    • 56649123256 scopus 로고    scopus 로고
    • The epidemiology of nonalcoholic fatty liver disease: A global perspective
    • Lazo M, Clark JM. The epidemiology of nonalcoholic fatty liver disease: a global perspective. Semin Liver Dis. 2008;28:339-350.
    • (2008) Semin Liver Dis , vol.28 , pp. 339-350
    • Lazo, M.1    Clark, J.M.2
  • 2
    • 77957302090 scopus 로고    scopus 로고
    • Hepatic steatosis: A role for de novo lipogene-sis and the transcription factor SREBP-1c
    • Ferré P, Foufelle F. Hepatic steatosis: a role for de novo lipogene-sis and the transcription factor SREBP-1c. Diabetes Obes Metab. 2010;12:83-92.
    • (2010) Diabetes Obes Metab , vol.12 , pp. 83-92
    • Ferré, P.1    Foufelle, F.2
  • 3
    • 77949311823 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: A review and update
    • Lewis JR, Mohanty SR. Nonalcoholic fatty liver disease: a review and update. Dig Dis Sci. 2010;55:560-578.
    • (2010) Dig Dis Sci , vol.55 , pp. 560-578
    • Lewis, J.R.1    Mohanty, S.R.2
  • 4
    • 84861130135 scopus 로고    scopus 로고
    • Histopatho-logical characteristics of non-alcoholic fatty liver disease in children: Comparison with adult cases
    • Takahashi Y, Inui A, Fujisawa T, Takikawa H, Fukusato T. Histopatho-logical characteristics of non-alcoholic fatty liver disease in children: comparison with adult cases. Hepatol Res. 2011;41:1066-1074.
    • (2011) Hepatol Res , vol.41 , pp. 1066-1074
    • Takahashi, Y.1    Inui, A.2    Fujisawa, T.3    Takikawa, H.4    Fukusato, T.5
  • 6
    • 84866520895 scopus 로고    scopus 로고
    • Is there any consensus as to what diet or lifestyle approach is the right one for NAFLD patients?
    • Finelli C, Tarantino G. Is there any consensus as to what diet or lifestyle approach is the right one for NAFLD patients? J Gastroin-testin Liver Dis. 2012;21:293-302.
    • (2012) J Gastroin-testin Liver Dis , vol.21 , pp. 293-302
    • Finelli, C.1    Tarantino, G.2
  • 7
    • 84872345173 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: Current and potential therapies
    • Ibrahim MA, Kelleni M, Geddawy A. Nonalcoholic fatty liver disease: current and potential therapies. Life Sciences. 2013;92:114-118.
    • (2013) Life Sciences , vol.92 , pp. 114-118
    • Ibrahim, M.A.1    Kelleni, M.2    Geddawy, A.3
  • 8
    • 84861318588 scopus 로고    scopus 로고
    • NADPH oxidase mediated oxidative stress in hepatic fbrogenesis
    • Paik Y-H, Brenner DA. NADPH oxidase mediated oxidative stress in hepatic fbrogenesis. Korean J Hepatol. 2011;17:251-257.
    • (2011) Korean J Hepatol , vol.17 , pp. 251-257
    • Paik, Y.-H.1    Brenner, D.A.2
  • 9
    • 77957342908 scopus 로고    scopus 로고
    • Reduced nicotinamide adenine dinucleotide phosphate oxidase 2 plays a key role in stellate cell activation and liver fbrogenesis in vivo
    • Jiang JX, Venugopal S, Serizawa N, Chen X, Scott F, Li Y, et al. Reduced nicotinamide adenine dinucleotide phosphate oxidase 2 plays a key role in stellate cell activation and liver fbrogenesis in vivo. Gastroenterology. 2010;139:1375-1384.
    • (2010) Gastroenterology , vol.139 , pp. 1375-1384
    • Jiang, J.X.1    Venugopal, S.2    Serizawa, N.3    Chen, X.4    Scott, F.5    Li, Y.6
  • 10
    • 77954236285 scopus 로고    scopus 로고
    • Hepatocyte NAD(P)H oxidases as an endogenous source of reactive oxygen species during hepatitis C virus infection
    • de Mochel NS, Seronello S, Wang SH, Ito C, Zheng JX, Liang TJ, et al. Hepatocyte NAD(P)H oxidases as an endogenous source of reactive oxygen species during hepatitis C virus infection. Hepa-tology. 2010;52:47-59.
    • (2010) Hepa-tology , vol.52 , pp. 47-59
    • de Mochel, N.S.1    Seronello, S.2    Wang, S.H.3    Ito, C.4    Zheng, J.X.5    Liang, T.J.6
  • 11
    • 0036796875 scopus 로고    scopus 로고
    • Oxidative stress and stress-activated signaling pathways: A unifying hypothesis of type 2 diabetes
    • Evans JL, Goldfne ID, Maddux BA, Grodsky GM. Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. Endocr Rev. 2002;23:599-622.
    • (2002) Endocr Rev , vol.23 , pp. 599-622
    • Evans, J.L.1    Goldfne, I.D.2    Maddux, B.A.3    Grodsky, G.M.4
  • 12
    • 84855421010 scopus 로고    scopus 로고
    • The anthocyanin cyanidin-3-O-β-glucoside, a favonoid, increases hepatic glutathione synthesis and protects hepatocytes against reactive oxygen species during hyperglycemia: Involvement of a cAMP-PKA-dependent signaling pathway
    • Zhu W, Jia Q, Wang Y, Zhang Y, Xia M. The anthocyanin cyanidin-3-O-β-glucoside, a favonoid, increases hepatic glutathione synthesis and protects hepatocytes against reactive oxygen species during hyperglycemia: Involvement of a cAMP-PKA-dependent signaling pathway. Free Radic Biol Med. 2012;52:314-327.
    • (2012) Free Radic Biol Med , vol.52 , pp. 314-327
    • Zhu, W.1    Jia, Q.2    Wang, Y.3    Zhang, Y.4    Xia, M.5
  • 13
    • 84864572232 scopus 로고    scopus 로고
    • The presence of p47phox in liver pa-renchymal cells is a key mediator in the pathogenesis of alcoholic liver steatosis
    • Levin I, Petrasek J, Szabo G. The presence of p47phox in liver pa-renchymal cells is a key mediator in the pathogenesis of alcoholic liver steatosis. Alcohol Clin Exp Res. 2012;36:1397-1406.
    • (2012) Alcohol Clin Exp Res , vol.36 , pp. 1397-1406
    • Levin, I.1    Petrasek, J.2    Szabo, G.3
  • 14
    • 33845680668 scopus 로고    scopus 로고
    • NADPH oxidase is not an essential mediator of oxidative stress or liver injury in mu-rine MCD diet-induced steatohepatitis
    • dela Pena A, Leclercq IA, Williams J, Farrell GC. NADPH oxidase is not an essential mediator of oxidative stress or liver injury in mu-rine MCD diet-induced steatohepatitis. J Hepatol. 2007;46:304-313.
    • (2007) J Hepatol , vol.46 , pp. 304-313
    • Dela Pena, A.1    Leclercq, I.A.2    Williams, J.3    Farrell, G.C.4
  • 15
    • 78649549021 scopus 로고    scopus 로고
    • Diversity in antioxidant response enzymes in progressive stages of human nonalcoholic fatty liver disease
    • Hardwick RN, Fisher CD, Canet MJ, Lake AD, Cherrington NJ. Diversity in antioxidant response enzymes in progressive stages of human nonalcoholic fatty liver disease. Drug Metab Dispos. 2010;38:2293-2301.
    • (2010) Drug Metab Dispos , vol.38 , pp. 2293-2301
    • Hardwick, R.N.1    Fisher, C.D.2    Canet, M.J.3    Lake, A.D.4    Cherrington, N.J.5
  • 16
    • 84861975560 scopus 로고    scopus 로고
    • Synergistic interaction of dietary cholesterol and dietary fat in inducing experimental steatohepatitis
    • Savard C, Tartaglione EV, Kuver R, Haigh WG, Farrell GC, Subra-manian S, et al. Synergistic interaction of dietary cholesterol and dietary fat in inducing experimental steatohepatitis. Hepatology. 2013;57:81-92.
    • (2013) Hepatology , vol.57 , pp. 81-92
    • Savard, C.1    Tartaglione, E.V.2    Kuver, R.3    Haigh, W.G.4    Farrell, G.C.5    Subra-Manian, S.6
  • 17
    • 67651148531 scopus 로고    scopus 로고
    • Association be-tween dietary nutrient composition and the incidence of cirrhosis or liver cancer in the United States population
    • Ioannou GN, Morrow OB, Connole ML, Lee SP. Association be-tween dietary nutrient composition and the incidence of cirrhosis or liver cancer in the United States population. Hepatology. 2009;50:175-184.
    • (2009) Hepatology , vol.50 , pp. 175-184
    • Ioannou, G.N.1    Morrow, O.B.2    Connole, M.L.3    Lee, S.P.4
  • 18
    • 78650492263 scopus 로고    scopus 로고
    • Acute effects of mi-crocystins exposure on the transcription of antioxidant enzyme genes in three organs (liver, kidney, and testis) of male Wistar rats
    • Xiong Q, Xie P, Li H, Hao L, Li G, Qiu T, et al. Acute effects of mi-crocystins exposure on the transcription of antioxidant enzyme genes in three organs (liver, kidney, and testis) of male Wistar rats. J Biochem Mol Toxicol. 2010;24:361-367.
    • (2010) J Biochem Mol Toxicol , vol.24 , pp. 361-367
    • Xiong, Q.1    Xie, P.2    Li, H.3    Hao, L.4    Li, G.5    Qiu, T.6
  • 19
    • 81455150032 scopus 로고    scopus 로고
    • Dietary açai modulates ROS production by neutrophils and gene expression of liver antioxidant enzymes in rats
    • Guerra JF, Magalhães CL, Costa DC, Silva ME, Pedrosa ML. Dietary açai modulates ROS production by neutrophils and gene expression of liver antioxidant enzymes in rats. J Clin Biochem Nutr. 2011;49:188-194.
    • (2011) J Clin Biochem Nutr , vol.49 , pp. 188-194
    • Guerra, J.F.1    Magalhães, C.L.2    Costa, D.C.3    Silva, M.E.4    Pedrosa, M.L.5
  • 20
    • 84857307663 scopus 로고    scopus 로고
    • Annatto extract and β-carotene enhances antioxidant status and regulate gene expression in neutrophils of diabetic rats
    • Rossoni Júnior JV, Araújo GR, Pádua Bda C, Magalhães CL, Chaves MM, Pedrosa ML, et al. Annatto extract and β-carotene enhances antioxidant status and regulate gene expression in neutrophils of diabetic rats. Free Radic Res. 2012;46:329-338.
    • (2012) Free Radic Res , vol.46 , pp. 329-338
    • Rossoni Júnior, J.V.1    Araújo, G.R.2    Pádua Bda, C.3    Magalhães, C.L.4    Chaves, M.M.5    Pedrosa, M.L.6
  • 21
    • 0021318441 scopus 로고
    • Catalase in vitro
    • Aebi H. Catalase in vitro. Methods Enzymol. 1984;105:121-126.
    • (1984) Methods Enzymol , vol.105 , pp. 121-126
    • Aebi, H.1
  • 22
    • 0017872475 scopus 로고
    • Microsomal lipid peroxidation
    • Buege JA, Aust SD. Microsomal lipid peroxidation. Methods En-zymol. 1978;52:302-310.
    • (1978) Methods En-zymol , vol.52 , pp. 302-310
    • Buege, J.A.1    Aust, S.D.2
  • 25
    • 33846821856 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: Predisposing factors and the role of nutrition
    • Cave M, Deaciuc I, Mendez C, Song Z, Joshi-Barve S, Barve S, et al. Nonalcoholic fatty liver disease: predisposing factors and the role of nutrition. J Nutr Biochem. 2007;18(3):184-195.
    • (2007) J Nutr Biochem , vol.18 , Issue.3 , pp. 184-195
    • Cave, M.1    Deaciuc, I.2    Mendez, C.3    Song, Z.4    Joshi-Barve, S.5    Barve, S.6
  • 27
    • 0034720287 scopus 로고    scopus 로고
    • Evaluation of abnormal liver-enzyme results in asymptomatic patients
    • Pratt DS, Marshall M, Kaplan MM. Evaluation of abnormal liver-enzyme results in asymptomatic patients. N Engl J Med. 2000;342:1266-1271.
    • (2000) N Engl J Med , vol.342 , pp. 1266-1271
    • Pratt, D.S.1    Marshall, M.2    Kaplan, M.M.3
  • 28
    • 42949154244 scopus 로고    scopus 로고
    • Diagnosis and therapy of nonalcoholic steatohepatitis
    • Torres DM, Harrison SA. Diagnosis and therapy of nonalcoholic steatohepatitis. Gastroenterology. 2008;134:1682-1698.
    • (2008) Gastroenterology , vol.134 , pp. 1682-1698
    • Torres, D.M.1    Harrison, S.A.2
  • 30
    • 33645536593 scopus 로고    scopus 로고
    • Treatment of non-alcoholic fatty liver disease
    • Adams LA, Angulo P. Treatment of non-alcoholic fatty liver disease. Postgrad Med J. 2006;82:315-322.
    • (2006) Postgrad Med J , vol.82 , pp. 315-322
    • Adams, L.A.1    Angulo, P.2
  • 31
    • 0029054173 scopus 로고
    • Nonalcoholic steatohepatitis: Tightening the morphological screws on a hepatic rambler
    • Lee RG. Nonalcoholic steatohepatitis: tightening the morphological screws on a hepatic rambler. Hepatology. 1995;21:1742-1743.
    • (1995) Hepatology , vol.21 , pp. 1742-1743
    • Lee, R.G.1
  • 33
    • 84869128653 scopus 로고    scopus 로고
    • Opuntia fcus indica (nopal) attenuates hepatic steatosis and oxidative stress in obese Zucker (fa/fa) rats
    • Morán-Ramos S, Avila-Nava A, Tovar AR, Pedraza-Chaverri J, López-Romero P, Torres N. Opuntia fcus indica (nopal) attenuates hepatic steatosis and oxidative stress in obese Zucker (fa/fa) rats. J Nutr. 2012;142(11):1956-1963.
    • (2012) J Nutr , vol.142 , Issue.11 , pp. 1956-1963
    • Morán-Ramos, S.1    Avila-Nava, A.2    Tovar, A.R.3    Pedraza-Chaverri, J.4    López-Romero, P.5    Torres, N.6
  • 34
    • 11244348954 scopus 로고    scopus 로고
    • A high-fat diet leads to the progression of non-alcoholic fatty liver disease in obese rats
    • Carmiel-Haggai M, Cederbaum AI, Nieto N. A high-fat diet leads to the progression of non-alcoholic fatty liver disease in obese rats. FASEB J. 2005;19:136-138.
    • (2005) FASEB J , vol.19 , pp. 136-138
    • Carmiel-Haggai, M.1    Cederbaum, A.I.2    Nieto, N.3
  • 35
    • 34047236886 scopus 로고    scopus 로고
    • Apocy-nin alleviated hepatic oxidative burden and reduced liver injury in hypercholesterolaemia
    • Lu LS, Wu CC, Hung LM, Chiang MT, Lin CT, Lin CW, et al. Apocy-nin alleviated hepatic oxidative burden and reduced liver injury in hypercholesterolaemia. Liver Int. 2007;27:529-537.
    • (2007) Liver Int , vol.27 , pp. 529-537
    • Lu, L.S.1    Wu, C.C.2    Hung, L.M.3    Chiang, M.T.4    Lin, C.T.5    Lin, C.W.6
  • 36
    • 80053616414 scopus 로고    scopus 로고
    • Reciprocal regulation of NA-DPH oxidases and the cyclooxygenase-2 pathway
    • Sancho P, Martín-sanz P, Fabregat I. Reciprocal regulation of NA-DPH oxidases and the cyclooxygenase-2 pathway. Free Radical Bio Med. 2011;5:1789-1798.
    • (2011) Free Radical Bio Med , vol.5 , pp. 1789-1798
    • Sancho, P.1    Martín-Sanz, P.2    Fabregat, I.3
  • 37
    • 0033105874 scopus 로고    scopus 로고
    • NADPH oxidase: An update
    • Babior BM. NADPH oxidase: an update. Blood. 1999;93:1464-1476.
    • (1999) Blood , vol.93 , pp. 1464-1476
    • Babior, B.M.1
  • 39
    • 0031015288 scopus 로고    scopus 로고
    • P22phox mRNA expression and NADPH oxidase activity are increased in aortas from hypertensive rats
    • Fukui T, Ishizaka N, Rajagopalan S, Laursen JB, Capers Q 4th, Taylor WR, et al. P22phox mRNA expression and NADPH oxidase activity are increased in aortas from hypertensive rats. Circ Res. 1997;80:45-51.
    • (1997) Circ Res , vol.80 , pp. 45-51
    • Fukui, T.1    Ishizaka, N.2    Rajagopalan, S.3    Laursen, J.B.4    Capers IV, Q.5    Taylor, W.R.6
  • 40
    • 28044466416 scopus 로고    scopus 로고
    • Measurement of the total antioxidant response using a novel automated method in subjects with nonalcoholic steatohep atitis
    • Horoz M, Bolukbas C, Bolukbas FF, Sabuncu T, Aslan M, Sarifakio-gullari S, et al. Measurement of the total antioxidant response using a novel automated method in subjects with nonalcoholic steatohep atitis. BMC Gastroenterol. 2005;5:35.
    • (2005) BMC Gastroenterol , vol.5 , pp. 35
    • Horoz, M.1    Bolukbas, C.2    Bolukbas, F.F.3    Sabuncu, T.4    Aslan, M.5    Sarifakio-Gullari, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.