Abnormalities in whole-brain functional connectivity observed in treatment-naive post-traumatic stress disorder patients following an earthquake

Psychological Medicine

Volumn 44, Issue 9, 2014, Pages 1927-1936

  Jin, C ^a   Qi, R ^b   Yin, Y ^a,c   Hu, X ^a   Duan, L ^a   Xu, Q ^b   Zhang, Z ^b   Zhong, Y ^b   Feng, B ^d   Xiang, H ^e   Gong, Q ^f   Liu, Y ^g   Lu, G ^b   Li, L ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b NANJING UNIVERSITY   (China)

^c The Seventh People's Hospital of Hangzhou   (China)

^d Mianzhu Psychiatric Hospital   (China)

^e Mental Health Center of Sichuan Province   (China)

^f SICHUAN UNIVERSITY   (China)

^g UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Key words Functional connectivity; post traumatic stress disorder; resting state functional magnetic resonance imaging

Indexed keywords

ADULT; BRAIN; CONNECTOME; DISASTER; EARTHQUAKE; FEMALE; HUMAN; MALE; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; POSTTRAUMATIC STRESS DISORDER;

ADULT; BRAIN; CONNECTOME; DISASTERS; EARTHQUAKES; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; STRESS DISORDERS, POST-TRAUMATIC;

EID: 84901466712     PISSN: 00332917     EISSN: 14698978     Source Type: Journal    
DOI: 10.1017/S003329171300250X     Document Type: Article

References (41)

1. Blake DD, Weathers FW, Nagy LM, Kaloupek DG, Gusman FD, Charney DS, Keane TM (1995). The development of a clinician-administered PTSD scale. Journal of Traumatic Stress 8, 75-90.
2. Blanchard EB, Jones-Alexander J, Buckley TC, Forneris CA (1996). Psychometric properties of the PTSD Checklist (PCL). Behaviour Research and Therapy 34, 669-673.
3. Bluhm RL, Williamson PC, Osuch EA, Frewen PA, Steven TK, Boksman K, Neufeld RW, Theberge J, Lanius RA (2009). Alterations in default network connectivity in posttraumatic stress disorder related to early-life trauma. Journal of Psychiatry and Neuroscience 34, 187-194.
4. Brady K, Pearlstein T, Asnis GM, Baker D, Rothbaum B, Sikes CR, Farfel GM (2000). Efficacy and safety of sertraline treatment of posttraumatic stress disorder: a randomized controlled trial. Journal of the American Medical Association 283, 1837-1844.
5. Braun K (2011). The prefrontal-limbic system: development, neuroanatomy, function, and implications for socioemotional development. Clinics in Perinatology 38, 685-702.
6. Bremner JD (2007). Functional neuroimaging in post-traumatic stress disorder. Expert Review of Neurotherapeutics 7, 393-405.
7. Chung YA, Kim SH, Chung SK, Chae JH, Yang DW, Sohn HS, Jeong J (2006). Alterations in cerebral perfusion in posttraumatic stress disorder patients without re-exposure to accident-related stimuli. Clinical Neurophysiology 117, 637-642.
8. Damoiseaux JS, Rombouts SA, Barkhof F, Scheltens P, Stam CJ, Smith SM, Beckmann CF (2006). Consistent resting-state networks across healthy subjects. Proceedings of the National Academy of Sciences USA 103, 13848-13853.
9. Ding J, Chen H, Qiu C, Liao W, Warwick JM, Duan X, Zhang W, Gong Q (2011). Disrupted functional connectivity in social anxiety disorder: a resting-state fMRI study. Magnetic Resonance Imaging 29, 701-711.
10. Etkin A, Wager TD (2007). Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia. American Journal of Psychiatry 164, 1476-1488.
11. First MB, Spitzer RL, Gibbon M, Williams JB (2002).Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Patient Edition. Biometrics Research, New York State Psychiatric Institute: New York.
12. Fornito A, Yoon J, Zalesky A, Bullmore ET, Carter CS (2011). General and specific functional connectivity disturbances in first-episode schizophrenia during cognitive control performance. Biological Psychiatry 70, 64-72.
13. Fox MD, Greicius M (2010). Clinical applications of resting state functional connectivity. Frontiers in Systems Neuroscience 4, 19.
14. Fox MD, Raichle ME (2007). Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging. Nature Reviews Neuroscience 8, 700-711.
15. Fox MD, Snyder AZ, Vincent JL, Corbetta M, Van Essen DC, Raichle ME (2005). The human brain is intrinsically organized into dynamic, anticorrelated functional networks. Proceedings of the National Academy of Sciences USA 102, 9673-9678.
16. Garrett AS, Carrion V, Kletter H, Karchemskiy A, Weems CF, Reiss A (2012). Brain activation to facial expressions in youth with PTSD symptoms. Depression and Anxiety 29, 449-459.
17. Ghashghaei HT, Hilgetag CC, Barbas H (2007). Sequence of information processing for emotions based on the anatomic dialogue between prefrontal cortex and amygdala. Neuroimage 34, 905-923.
18. Greicius MD, Srivastava G, Reiss AL, Menon V (2004). Default-mode network activity distinguishes Alzheimer's disease from healthy aging: evidence from functional MRI. Proceedings of the National Academy of Sciences USA 101, 4637-4642.
19. Hughes KC, Shin LM (2011). Functional neuroimaging studies of post-traumatic stress disorder. Expert Review of Neurotherapeutics 11, 275-285.
20. Jao T, Vertes PE, Alexander-Bloch AF, Tang IN, Yu YC, Chen JH, Bullmore ET (2013). Volitional eyes opening perturbs brain dynamics and functional connectivity regardless of light input. Neuroimage 69, 21-34.
21. Lanius RA, Bluhm RL, Coupland NJ, Hegadoren KM, Rowe B, Theberge J, Neufeld RW, Williamson PC, Brimson M (2010). Default mode network connectivity as a predictor of post-traumatic stress disorder symptom severity in acutely traumatized subjects. Acta Psychiatrica Scandinavica 121, 33-40.
22. Lee MH, Smyser CD, Shimony JS (2012). Resting-state fMRI: a review of methods and clinical applications. American Journal of Neuroradiology. Published online 30 August 2012. doi:10.3174/anjr.A3263.
23. Levin P, Lazrove S, van der Kolk B (1999). What psychological testing and neuroimaging tell us about the treatment of posttraumatic stress disorder by eye movement desensitization and reprocessing. Journal of Anxiety Disorders 13, 159-172.
24. Liao W, Chen H, Feng Y, Mantini D, Gentili C, Pan Z, Ding J, Duan X, Qiu C, Lui S, Gong Q, Zhang W (2010). Selective aberrant functional connectivity of resting state networks in social anxiety disorder. Neuroimage 52, 1549-1558.
25. Liberzon I, Phan KL (2003). Brain-imaging studies of posttraumatic stress disorder. CNS Spectrums 8, 641-650.
26. Lowe MJ, Dzemidzic M, Lurito JT, Mathews VP, Phillips MD (2000). Correlations in low-frequency BOLD fluctuations reflect cortico-cortical connections. Neuroimage 12, 582-587.
27. Maldjian JA, Laurienti PJ, Kraft RA, Burdette JH (2003). An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets. Neuroimage 19, 1233-1239.
28. Mantini D, Perrucci MG, Del Gratta C, Romani GL, Corbetta M (2007). Electrophysiological signatures of resting state networks in the human brain. Proceedings of the National Academy of Sciences USA 104, 13170-13175.
29. Pessoa L (2008). On the relationship between emotion and cognition. Nature Reviews Neuroscience 9, 148-158.
30. Rabinak CA, Angstadt M, Welsh RC, Kenndy AE, Lyubkin M, Martis B, Phan KL (2011). Altered amygdala resting-state functional connectivity in post-traumatic stress disorder. Frontiers in Psychiatry 2, 62.
31. Raichle ME, MacLeod AM, Snyder AZ, Powers WJ, Gusnard DA, Shulman GL (2001). A default mode of brain function. Proceedings of the National Academy of Sciences USA 98, 676-682.
32. Shin LM, Orr SP, Carson MA, Rauch SL, Macklin ML, Lasko NB, Peters PM, Metzger LJ, Dougherty DD, Cannistraro PA, Alpert NM, Fischman AJ, Pitman RK (2004). Regional cerebral blood flow in the amygdala and medial prefrontal cortex during traumatic imagery in male and female Vietnam veterans with PTSD. Archives of General Psychiatry 61, 168-176.
33. Shin LM, Wright CI, Cannistraro PA, Wedig MM, McMullin K, Martis B, Macklin ML, Lasko NB, Cavanagh SR, Krangel TS, Orr SP, Pitman RK, Whalen PJ, Rauch SL (2005). A functional magnetic resonance imaging study of amygdala and medial prefrontal cortex responses to overtly presented fearful faces in posttraumatic stress disorder. Archives of General Psychiatry 62, 273-281.
34. Sripada RK, King AP, Garfinkel SN, Wang X, Sripada CS, Welsh RC, Liberzon I (2012a). Altered resting-state amygdala functional connectivity in men with posttraumatic stress disorder. Journal of Psychiatry and Neuroscience 37, 241-249.
35. Sripada RK, King AP, Welsh RC, Garfinkel SN, Wang X, Sripada CS, Liberzon I (2012b). Neural dysregulation in posttraumatic stress disorder: evidence for disrupted equilibrium between salience and default mode brain networks. Psychosomatic Medicine 74, 904-911.
36. Tamminga CA, Buchsbaum MS (2004). Frontal cortex function. American Journal of Psychiatry 161, 2178.
37. Williams LM, Kemp AH, Felmingham K, Barton M, Olivieri G, Peduto A, Gordon E, Bryant RA (2006). Trauma modulates amygdala and medial prefrontal responses to consciously attended fear. Neuroimage 29, 347-357.
38. Woodward ND, Karbasforoushan H, Heckers S (2012). Thalamocortical dysconnectivity in schizophrenia. American Journal of Psychiatry 169, 1092-1099.
39. Yin Y, Jin C, Hu X, Duan L, Li Z, Song M, Chen H, Feng B, Jiang T, Jin H, Wong C, Gong Q, Li L (2011a). Altered resting-state functional connectivity of thalamus in earthquake-induced posttraumatic stress disorder: a functional magnetic resonance imaging study. Brain Research 1411, 98-107.
40. Yin Y, Li L, Jin C, Hu X, Duan L, Eyler LT, Gong Q, Song M, Jiang T, Liao M, Zhang Y, LiW(2011b). Abnormal baseline brain activity in posttraumatic stress disorder: a resting-state functional magnetic resonance imaging study. Neuroscience Letters 498, 185-189.
41. Zhang LJ, Zheng G, Zhang L, Zhong J, Wu S, Qi R, Li Q, Wang L, Lu G (2012). Altered brain functional connectivity in patients with cirrhosis and minimal hepatic encephalopathy: a functional MR imaging study. Radiology 265, 528-536.