"But it might be a heart attack": Intolerance of uncertainty and panic disorder symptoms

Journal of Anxiety Disorders

Volumn 28, Issue 5, 2014, Pages 463-470

  Carleton, R Nicholas ^a   Duranceau, Sophie ^a   Freeston, Mark H ^b   Boelen, Paul A ^c   McCabe, Randi E ^d   Antony, Martin M ^e  

^a UNIVERSITY OF REGINA   (Canada)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c UTRECHT UNIVERSITY   (Netherlands)

^d MCMASTER UNIVERSITY   (Canada)

^e RYERSON UNIVERSITY   (Canada)

Author keywords

Anxiety sensitivity; Intolerance of uncertainty; Panic; Panic disorder

Indexed keywords

ADULT; AGORAPHOBIA; ANXIETY; ANXIETY SENSITIVITY; ARTICLE; COGNITIVE DEFECT; CONFUSION (UNCERTAINTY); COPING BEHAVIOR; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; DSM-IV-TR; EVIDENCE BASED MEDICINE; FEMALE; HUMAN; INTOLERANCE OF UNCERTAINTY; MAJOR CLINICAL STUDY; MALE; PANIC; PSYCHOSOMATIC DISORDER; SYMPTOM;

ANXIETY SENSITIVITY; INTOLERANCE OF UNCERTAINTY; PANIC; PANIC DISORDER;

ADULT; AGORAPHOBIA; ANXIETY; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; PANIC DISORDER; UNCERTAINTY;

EID: 84901437887     PISSN: 08876185     EISSN: 18737897     Source Type: Journal    
DOI: 10.1016/j.janxdis.2014.04.006     Document Type: Article

References (84)

1. American Psychiatric Association Diagnostic and statistical manual of mental disorders 2000, Author, Washington, DC. 4th ed., text revision ed.
2. American Psychiatric Association Diagnostic and statistical manual of mental disorders 2013, Author, Washington, DC. 5th ed.
3. Apfeldorf W.J., Shear M.K., Leon A.C., Portera L. A brief screen for panic disorder. Journal of Anxiety Disorders 1994, 10:71-78. 10.1016/0887-6185(94)90024-8.
4. Barlow D.H. Anxiety and its disorders: the nature and treatment of anxiety and panic 2002, Guilford Press, New York, NY. 2nd ed.
5. Barlow D.H., Allen L.B., Choate M.L. Toward a unified treatment for emotional disorders. Behavior Therapy 2004, 35:205-230.
6. Barlow D.H., Gorman J.M., Shear M.K., Woods S.W. Cognitive-behavioral therapy, imipramine, or their combination for panic disorder: A randomized controlled trial. Journal of the American Medical Association 2000, 283:2529-2536.
7. Barlow D.H., Sauer-Zavala S., Carl J.R., Bullis J.R., Ellard K.K. The nature, diagnosis, and treatment of neuroticism: Back to the future. Clinical Psychological Science 2014, (in press). 10.1177/2167702613505532.
8. Beck A.T., Steer R.A., Ball R., Ranieri W.F. Comparison of beck depression inventories-IA and -II in psychiatric outpatients. Journal of Personality Assessment 1996, 67:588-597.
9. Bernstein A., Stickle T.R., Zvolensky M.J., Taylor S., Abramowitz J., Stewart S. Dimensional, categorical, or dimensional-categories: Testing the latent structure of anxiety sensitivity among adults using factor-mixture modeling. Behavior Therapy 2010, 41:515-529. 10.1016/j.beth.2010.02.003.
10. Bernstein A., Zvolensky M.J., Norton P.J., Schmidt N.B., Taylor S., Forsyth J.P., et al. Taxometric and factor analytic models of anxiety sensitivity: Integrating approaches to latent structural research. Psychological Assessment 2007, 19:74-87. 2007-03014-007. 10.1037/1040-3590.19.1.74.
11. Birrell J., Meares K., Wilkinson A., Freeston M. Toward a definition of intolerance of uncertainty: A review of factor analytical studies of the intolerance of uncertainty scale. Clinical Psychology Review 2011, 31:1198-1208. 10.1016/j.cpr.2011.07.009.
12. Boelen P.A., Carleton R.N. Intolerance of uncertainty, hypochondriacal concerns, OCD, and worry. Journal of Nervous and Mental Disease 2012, 200:208-213. 10.1097/NMD.0b013e318247cb17.
13. Boelen P.A., Reijntjes A. Intolerance of uncertainty and social anxiety. Journal of Anxiety Disorders 2009, 23:130-135. 10.1016/j.janxdis.2008.04.007.
14. Boelen P.A., Vrinssen I., van Tulder F. Intolerance of uncertainty in adolescents: Correlations with worry, social anxiety, and depression. Journal of Nervous and Mental Disease 2010, 198:194-200. 10.1097/NMD.0b013e3181d143de.
15. Boswell J.F., Thompson-Hollands J., Farchione T.J., Barlow D.H. Intolerance of uncertainty: A common factor in the treatment of emotional disorders. Journal of Clinical Psychology 2013, 69:630-645. 10.1002/jclp.21965.
16. Buhr K., Dugas M.J. Investigating the construct validity of intolerance of uncertainty and its unique relationship with worry. Journal of Anxiety Disorders 2006, 12:222-236. S0887-6185(05)00022-8. 10.1016/j.janxdis.2004.12.004.
17. Carleton R.N. The intolerance of uncertainty construct in the context of anxiety disorders: Theoretical and practical perspectives. Expert Review of Neurotherapeutics 2012, 12:937-947. 10.1586/ERN.12.82.
18. Carleton R.N., Collimore K.C., Asmundson G.J.G. "It's not just the judgements - it's that I don't know": Intolerance of uncertainty as a predictor of social anxiety. Journal of Anxiety Disorders 2010, 24:189-195. 10.1016/j.janxdis.2009.10.007.
19. Carleton R.N., Fetzner M.G., Hackl J.L., McEvoy P. Intolerance of uncertainty as a contributor to fear and avoidance symptoms of panic attacks. Cognitive Behavior Therapy 2013, 10.1080/16506073.2013.792100.
20. Carleton R.N., Mulvogue M.K., Thibodeau M.A., McCabe R.E., Antony M.M., Asmundson G.J.G. Increasingly certain about uncertainty: Intolerance of uncertainty across anxiety and depression. Journal of Anxiety Disorders 2012, 26:468-479. 10.1016/j.janxdis.2012.01.011.
21. Carleton R.N., Norton P.J., Asmundson G.J.G. Fearing the unknown: a short version of the intolerance of uncertainty scale. Journal of Anxiety Disorders 2007, 21:105-117. S0887-6185(06)00051-X. 10.1016/j.janxdis.2006.03.014.
22. Carleton R.N., Sharpe D., Asmundson G.J.G. Anxiety sensitivity and intolerance of uncertainty: Requisites of the fundamental fears?. Behavior Research and Therapy 2007, 45:2307-2316. S0005-7967(07)00095-2. 10.1016/j.brat.2007.04.006.
23. Carleton R.N., Weeks J.W., Howell A.N., Asmundson G.J.G., Antony M.M., McCabe R.E. Assessing the latent structure of the intolerance of uncertainty construct: An initial taxometric analysis. Journal of Anxiety Disorders 2012, 26:150-157. 10.1016/j.janxdis.2011.10.006.
24. Clark D.M. A cognitive approach to panic. Behaviour Research and Therapy 1986, 24:461-470.
25. Cohen J. Statistical power analysis for the behavioral sciences 1988, Lawrence Erlbaum, Mawah, NJ. 2nd ed.
26. Curran P.J., West S.G., Finch J.F. The robustness of test statistics to nonnormality and specification error in confirmatory factor analysis. Psychological Methods 1996, 1:16-29. 10.1037/1082-989X.1.1.16.
27. Dawson N.V., Weiss R. Dichotomizing continuous variables in statistical analysis: A practice to avoid. Medical Decision Making 2012, 32:225-226. 10.1177/0272989 × 12437605.
28. Deacon B., Abramowitz J. Anxiety sensitivity and its dimensions across the anxiety disorders. Journal of Anxiety Disorders 2006, 20:837-857. 10.1016/j.janxdis.2006.01.003.
29. Dugas M.J., Buhr K., Ladouceur R. The role of intolerance of uncertainty in the etiology and maintenance of generalized anxiety disorder. Generalized anxiety disorder: advances in research and practice 2004, 143-163. Guilford Press, New York, NY. R.G. Heimberg, C.L. Turk, D.S. Mennin (Eds.).
30. Dugas M.J., Gosselin P., Landouceur R. Intolerance of uncertainty and worry: Investigating specificity in a nonclinical sample. Cognitive Therapy and Research 2001, 25:551-558. 10.1023/A:1005553414688.
31. Dugas M.J., Hedayati M., Karavidas A., Buhr K., Francis K., Phillips N.A. Intolerance of uncertainty and information processing: Evidence of biased recall and interpretations. Cognitive Therapy and Research 2005, 29:57-70. 10.1007/s10608-005-1648-9.
32. Dugas M.J., Ladouceur R. Treatment of GAD. Targeting intolerance of uncertainty in two types of worry. Behavior Modification 2000, 24:635-657.
33. Dugas M.J., Marchand A., Ladouceur R. Further validation of a cognitive-behavioral model of generalized anxiety disorder: Diagnostic and symptom specificity. Journal of Anxiety Disorders 2005, 19:329-343. 10.1016/j.janxdis.2004.02.002.
34. Dugas M.J., Robichaud M. Cognitive-behavioral treatment for generalized anxiety disorder: from science to practice 2007, Routledge, New York, NY.
35. Dugas M.J., Schwartz A., Francis K. Intolerance of uncertainty, worry, and depression. Cognitive Therapy and Research 2004, 28:835-842. 10.1007/s10608-004-0669-0.
36. Erdfelder E., Faul F., Buchner A. GPOWER: A general power analysis program. Behavior Research Methods, Instruments and Computers 1996, 28:1-11.
37. First M.B., Gibbon M., Spitzer R.L., Williams J.B.W. Structured clinical interview for DSM-IV Axis I disorders - patient edition 2002, New York State Psychiatric Institute, Biometrics Research Department, New York, NY.
38. Freeston M., Rhéaume J., Letarte H., Dugas M.J., Ladouceur R. Why do people worry?. Personality and Individual Differences 1994, 17:791-802. 10.1016/0191-8869(94)90048-5.
39. Gentes E.L., Ruscio A.M. A meta-analysis of the relation of intolerance of uncertainty to symptoms of generalized anxiety disorder, major depressive disorder, and obsessive-compulsive disorder. Clinical Psychology Review 2011, 31:923-933. 10.1016/j.cpr.2011.05.001.
40. Grant D.M., Beck J.G., Davila J. Does anxiety sensitivity predict symptoms of panic, depression, and social anxiety?. Behaviour Research and Therapy 2007, 45:2247-2255.
41. Grupe D.W., Nitschke J.B. Uncertainty and anticipation in anxiety: An integrated neurobiological and psychological perspective. Nature Reviews Neuroscience 2013, 14:488-501. 10.1038/nrn3524.
42. Hayes A.F. An introduction to mediation, moderation, and conditional process analysis: a regression-based approach 2013, Guilford Press, New York, NY.
43. Holaway R.M., Heimberg R.G., Coles M.E. A comparison of intolerance of uncertainty in analogue obsessive-compulsive disorder and generalized anxiety disorder. Journal of Anxiety Disorders 2006, 20:158-174. 10.1037/1528-3542.4.1.65.
44. Khawaja N.G., Yu L.N.H. A comparison of the 27-item and 12-item intolerance of uncertainty scales. Clinical Psychologist 2010, 14:97-106. 10.1080/13284207.2010.502542.
45. Koerner N., Dugas M.J. An investigation of appraisals in individuals vulnerable to excessive worry: The role of intolerance of uncertainty. Cognitive Therapy and Research 2008, 32:619-638. 10.1007/s10608-007-9125-2.
46. Ladouceur R., Dugas M.J., Freeston M.H., Leger E., Gagnon F., Thibodeau N. Efficacy of a cognitive-behavioral treatment for generalized anxiety disorder: Evaluation in a controlled clinical trial. Journal of Consulting and Clinical Psychology 2000, 68:957-964.
47. Mahoney A.E., McEvoy P.M. Changes in intolerance of uncertainty during cognitive behavior group therapy for social phobia. Journal of Behavior Therapy and Experimental Psychiatry 2012, 43:849-854. 10.1016/j.jbtep.2011.12.004.
48. Mahoney A.E., McEvoy P.M. Trait versus situation-specific intolerance of uncertainty in a clinical sample with anxiety and depressive disorders. Cognitive Behaviour Therapy 2012, 41:26-39. 10.1080/16506073.2011.622131.
49. Mahoney A.E., McEvoy P.M. A transdiagnostic examination of intolerance of uncertainty across anxiety and depressive disorders. Cognitive Behaviour Therapy 2012, 41:212-222. 10.1080/16506073.2011.622130.
50. Maller R.G., Reiss S. Anxiety sensitivity in 1984 and panic attacks in 1987. Journal of Anxiety Disorders 1987, 6:241-247. 10.1016/0887-6185(92)90036-7.
51. Manfro G.G., Heldt E., Cordioli A.V., Otto M.W. Cognitive behavioural therapy in panic disorder. Revista Brasileira de Psiquiatria 2008, 30:s81-s87.
52. McEvoy P.M., Mahoney A.E. Achieving certainty about the structure of intolerance of uncertainty in a treatment-seeking sample with anxiety and depression. Journal of Anxiety Disorders 2011, 25:112-122. 10.1016/j.janxdis.2010.08.010.
53. McEvoy P.M., Mahoney A.E. To be sure, to be sure: Intolerance of uncertainty mediates symptoms of various anxiety disorders and depression. Behavior Therapy 2012, 43:533-545. 10.1016/j.beth.2011.02.007.
54. McLeish A.C., Zvolensky M.J., Bucossi M.M. Interaction between smoking rate and anxiety sensitivity: Relation to anticipatory anxiety and panic-relevant avoidance among daily smokers. Journal of Anxiety Disorders 2007, 21:849-859. 10.1016/j.janxdis.2006.11.003.
55. McNally R.J. Anxiety sensitivity and panic disorder. Biological Psychiatry 2002, 52:938-946.
56. Meuret A.E., White K.S., Ritz T., Roth W.T., Hofmann S.G., Brown T.A. Panic attack symptom dimensions and their relationship to illness characteristics in panic disorder. Journal of Psychiatric Research 2006, 40:520-527. 10.1016/j.jpsychires.2005.09.006.
57. Naragon-Gainey K. Meta-analysis of the relations of anxiety sensitivity to the depressive and anxiety disorders. Psychological Bulletin 2010, 136:128-150. 10.1037/a0018055.
58. Norton P.J., Sexton K.A., Walker J.R., Norton G.R. Hierarchical model of vulnerabilities for anxiety: Replication and extension with a clinical sample. Cognitive Behaviour Therapy 2005, 34:50-63. 10.1080/16506070410005401.
59. Orsillo S.M. Measures for social phobia. Practitioner's guide to empirically based measures of anxiety 2001, 165-187. Springer, New York, NY. M.M. Antony, S.M. Orsillo, L. Roemer (Eds.).
60. Peterson R.A., Reiss S. Anxiety sensitivity index manual 1992, International Diagnostic Systems, Worthington, OH. 2nd ed.
61. Petrocelli J.V. Hierarchical multiple regression in counseling research: Common problems and possible remedies. Measurement and Evaluation in Counseling and Development 2003, 36:9-22. 10.1037/a0013021.
62. Preacher K.J., Rucker D.D., Hayes A.F. Addressing moderated mediation hypotheses: Theory, methods, and prescriptions. Multivariate Behavioral Research 2007, 42:185-227. 10.1080/00273170701341316.
63. Reiss S., McNally R.J. The expectancy model of fear. Theoretical issues in behaviour therapy 1985, 107-121. Academic Press, New York, NY. S. Reiss, R.R. Bootzin (Eds.).
64. Rhemtulla M., Brosseau-Liard P.E., Savalei V. When can categorical variables be treated as continuous? A comparison of robust continuous and categorical SEM estimation methods under suboptimal conditions. Psychological Methods 2012, 17:354-373. 10.1037/a0029315.
65. Rosen N.O., Knauper B., Di Dio P., Morrison E., Tabing R., Feldstain A., et al. The impact of intolerance of uncertainty on anxiety after receiving an informational intervention about HPV: A randomised controlled study. Psychology & Health 2010, 25:651-668. 10.1080/08870440902822913.
66. Schmidt N.B., Lerew D.R., Jackson R.J. The role of anxiety sensitivity in the pathogenesis of panic: Prospective evaluation of spontaneous panic attacks during acute stress. Journal of Abnormal Psychology 1997, 106:355-364. 10.1037/0021-843X.106.3.355.
67. Sexton K.A., Norton P.J., Walker J.R., Norton G.R. Hierarchical model of generalized and specific vulnerabilities in anxiety. Cognitive Behaviour Therapy 2003, 32:82-94. 10.1080/16506070302321.
68. Shear M.K., Rucci P., Williams J., Frank E., Grochocinski V., Vander Bilt J., et al. Reliability and validity of the panic disorder severity scale: Replication and extension. Journal of Psychiatric Research 2001, 35:293-296. S0022-3956(01)00028-0.
69. Smits J.A.J., Powers M.B., Cho Y., Telch M.J. Mechanism of change in cognitive-behavioral treatment of panic disorder: Evidence for the fear of fear mediational hypothesis. Journal of Consulting and Clinical Psychology 2004, 72:646-652. 10.1037/0022-006X.72.4.646.
70. Starcevic V., Berle D. Cognitive specificity of anxiety disorders: A review of selected key constructs. Depression and Anxiety 2006, 23:51-61. 10.1002/da.20145.
71. Streiner D.L. Breaking up is hard to do: The heartbreak of dichotomizing continuous data. Canadian Journal of Psychiatry 2002, 47:262-266.
72. Suárez L., Bennett S., Goldstein C., Barlow D.H. Understanding anxiety disorders from a "triple vulnerability" framework. Handbook of anxiety and related disorders 2009, 153-172. Oxford University Press, New York, NY. M.M. Antony, M.B. Stein (Eds.).
73. Tabachnick B.G., Fidell L.S. Using multivariate statistics 2013, Allyn and Bacon, Boston, MA. 6th ed.
74. Taylor S. Anxiety sensitivity: theory, research, and treatment of the fear of anxiety 1999, Lawrence Erlbaum, Mahwah, NJ.
75. Taylor S., Koch W.J., McNally R.J. How does anxiety sensitivity vary across the anxiety disorders?. Journal of Anxiety Disorders 1992, 6:249-259. 10.1016/0887-6185(92)90037-8.
76. Taylor S., Koch W.J., Woody S., McLean P. Anxiety sensitivity and depression: How are they related?. Journal of Abnormal Psychology 1996, 105:474-479. 10.1037/0021-843X.105.3.474.
77. Taylor S., Zvolensky M.J., Cox B.J., Deacon B., Heimberg R.G., Ledley D.R., et al. Robust dimensions of anxiety sensitivity: Development and initial validation of the anxiety sensitivity index-3. Psychological Assessment 2007, 19:176-188. 2007-07953-002. 10.1037/1040-3590.19.2.176.
78. Tolin D.F., Abramowitz J.S., Brigidi B.D., Foa E.B. Intolerance of uncertainty in obsessive-compulsive disorder. Journal of Anxiety Disorders 2003, 17:233-242. 10.1016/S0887-6185(02)00182-2.
79. Vujanovic A.A., Arrindell W.A., Bernstein A., Norton P.J., Zvolensky M.J. Sixteen-item anxiety sensitivity index: Confirmatory factor analytic evidence, internal consistency, and construct validity in a young adult sample from the Netherlands. Assessment 2007, 14:129-143. 10.1177/1073191106295053.
80. Wu P., Goodwin R.D., Fuller C., Liu X., Comer J.S., Cohen P., et al. The relationship between anxiety disorders and substance use among adolescents in the community: Specificity and gender differences. Journal of Youth and Adolescence 2010, 39:177-188. 10.1007/s10964-008-9385-5.
81. Wuyek L.A., Antony M.M., McCabe R.E. Psychometric properties of the panic disorder severity scale: Clinician-administered and self-report versions. Clinical Psychology & Psychotherapy 2011, 18:234-243. 10.1002/cpp.703.
82. Zanarini M.C., Frankenburg F.R. Attainment and maintenance of reliability of axis I and II disorders over the course of a longitudinal study. Comprehensive Psychiatry 2001, 42:369-374. S0010-440X(01)63326-1. 10.1053/comp.2001.24556.
83. Zinbarg R.E., Barlow D.H., Brown T.A. Hierarchical structure and general factor saturation of the anxiety sensitivity index. Psychological Assessment 1997, 9:277-284. 10.1037/1040-3590.9.3.277.
84. Zvolensky M.J., Forsyth J.P. Anxiety sensitivity dimensions in the prediction of body vigilance and emotional avoidance. Cognitive Therapy and Research 2002, 26:449-460. 10.1023/A:1016223716132.