Effect of the pretransplant serum sodium concentration on outcomes following liver transplantation

Liver Transplantation

Volumn 20, Issue 6, 2014, Pages 687-697

  Leise, Michael D ^a   Yun, Byung Cheol ^b   Larson, Joseph J ^a   Benson, Joanne T ^a   Yang, Ju Dong ^a   Therneau, Terry M ^a   Rosen, Charles B ^a   Heimbach, Julie K ^a   Biggins, Scott W ^c   Kim, W Ray ^a  

^a MAYO CLINIC   (United States)

^b Kosin University College of Medicine   (South Korea)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SODIUM; BIOLOGICAL MARKER;

ADULT; ARTICLE; FEMALE; HUMAN; HYPERNATREMIA; HYPONATREMIA; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MORTALITY; OUTCOME ASSESSMENT; POPULATION RESEARCH; PRIORITY JOURNAL; SODIUM BLOOD LEVEL; SURVIVAL; BLOOD; COMPLICATION; KAPLAN MEIER METHOD; LENGTH OF STAY; LIVER FAILURE; MIDDLE AGED; PROPORTIONAL HAZARDS MODEL; REGISTER; RISK FACTOR; TIME; TREATMENT OUTCOME;

BIOLOGICAL MARKERS; FEMALE; HOSPITAL MORTALITY; HUMANS; HYPERNATREMIA; HYPONATREMIA; KAPLAN-MEIER ESTIMATE; LENGTH OF STAY; LIVER FAILURE; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; PROPORTIONAL HAZARDS MODELS; REGISTRIES; RISK FACTORS; SODIUM; TIME FACTORS; TREATMENT OUTCOME;

EID: 84901407412     PISSN: 15276465     EISSN: 15276473     Source Type: Journal    
DOI: 10.1002/lt.23860     Document Type: Article

References (32)

1. Ginès A, Escorsell A, Ginès P, Salõ J, Jiménez W, Inglada L, et al. Incidence, predictive factors, and prognosis of the hepatorenal syndrome in cirrhosis with ascites. Gastroenterology 1993; 105: 229-236.
2. Ginés P, Berl T, Bernardi M, Bichet DG, Hamon G, Jiménez W, et al. Hyponatremia in cirrhosis: from pathogenesis to treatment. Hepatology 1998; 28: 851-864.
3. Ruf AE, Kremers WK, Chavez LL, Descalzi VI, Podesta LG, Villamil FG,. Addition of serum sodium into the MELD score predicts waiting list mortality better than MELD alone. Liver Transpl 2005; 11: 336-343.
4. Follo A, Llovet JM, Navasa M, Planas R, Forns X, Francitorra A, et al. Renal impairment after spontaneous bacterial peritonitis in cirrhosis: incidence, clinical course, predictive factors and prognosis. Hepatology 1994; 20: 1495-1501.
5. Guevara M, Baccaro ME, Torre A, Gõmez-Ansõn B, Ríos J, Torres F, et al. Hyponatremia is a risk factor of hepatic encephalopathy in patients with cirrhosis: a prospective study with time-dependent analysis. Am J Gastroenterol 2009; 104: 1382-1389.
6. Häussinger D,. Low grade cerebral edema and the pathogenesis of hepatic encephalopathy in cirrhosis. Hepatology 2006; 43: 1187-1190.
7. Heuman DM, Abou-Assi SG, Habib A, Williams LM, Stravitz RT, Sanyal AJ, et al. Persistent ascites and low serum sodium identify patients with cirrhosis and low MELD scores who are at high risk for early death. Hepatology 2004; 40: 802-810.
8. Ginès P, Guevara M,. Hyponatremia in cirrhosis: pathogenesis, clinical significance, and management. Hepatology 2008; 48: 1002-1010.
9. Kim WR, Biggins SW, Kremers WK, Wiesner RH, Kamath PS, Benson JT, et al. Hyponatremia and mortality among patients on the liver-transplant waiting list. N Engl J Med 2008; 359: 1018-1026.
10. Biggins SW, Kim WR, Terrault NA, Saab S, Balan V, Schiano T, et al. Evidence-based incorporation of serum sodium concentration into MELD. Gastroenterology 2006; 130: 1652-1660.
11. Londoño MC, Guevara M, Rimola A, Navasa M, Taurà P, Mas A, et al. Hyponatremia impairs early posttransplantation outcome in patients with cirrhosis undergoing liver transplantation. Gastroenterology 2006; 130: 1135-1143.
12. Dawwas MF, Lewsey JD, Neuberger JM, Gimson AE,. The impact of serum sodium concentration on mortality after liver transplantation: a cohort multicenter study. Liver Transpl 2007; 13: 1115-1124.
13. Yun BC, Kim WR, Benson JT, Biggins SW, Therneau TM, Kremers WK, et al. Impact of pretransplant hyponatremia on outcome following liver transplantation. Hepatology 2009; 49: 1610-1615.
14. Hackworth WA, Heuman DM, Sanyal AJ, Fisher RA, Sterling RK, Luketic VA, et al. Effect of hyponatraemia on outcomes following orthotopic liver transplantation. Liver Int 2009; 29: 1071-1077.
15. Yun BC, Kim WR, Benson JT, Biggins SW, Therneau TM, Kremers WK, et al. Impact of pretransplant hyponatremia on outcome following liver transplantation. Hepatology. 2009; 49: 1610-1615.
16. Warren SE, Mitas JA II, Swerdlin AH,. Hypernatremia in hepatic failure. JAMA 1980; 243: 1257-1260.
17. Shorr AF, Tabak YP, Johannes RS, Gupta V, Saltzberg MT, Costanzo MR,. Burden of sodium abnormalities in patients hospitalized for heart failure. Congest Heart Fail 2011; 17: 1-7.
18. Kovesdy CP, Lott EH, Lu JL, Malakauskas SM, Ma JZ, Molnar MZ, Kalantar-Zadeh K,. Hyponatremia, hypernatremia, and mortality in patients with chronic kidney disease with and without congestive heart failure. Circulation 2012; 125: 677-684.
19. Waite MD, Fuhrman SA, Badawi O, Zuckerman IH, Franey CS,. Intensive care unit-acquired hypernatremia is an independent predictor of increased mortality and length of stay. J Crit Care 2013; 28: 405-412.
20. Arampatzis S, Frauchiger B, Fiedler GM, Leichtle AB, Buhl D, Schwarz C, et al. Characteristics, symptoms, and outcome of severe dysnatremias present on hospital admission. Am J Med 2012; 125: 1125.e1-1125.e7.
21. Fisher RA, Heuman DM, Harper AM, Behnke MK, Smith AD, Russo MW, et al. Region 11 MELD Na exception prospective study. Ann Hepatol 2012; 11: 62-67.
22. Long CA, Marin P, Bayer AJ, Shetty HG, Pathy MS,. Hypernatraemia in an adult in-patient population. Postgrad Med J 1991; 67: 643-645.
23. Palevsky PM, Bhagrath R, Greenberg A,. Hypernatremia in hospitalized patients. Ann Intern Med 1996; 124: 197-203.
24. O'Connor KA, Cotter PE, Kingston M, Twomey C, O'Mahony D,. The pattern of plasma sodium abnormalities in an acute elderly care ward: a cross-sectional study. Ir J Med Sci 2006; 175: 28-31.
25. Mandal AK, Saklayen MG, Hillman NM, Markert RJ,. Predictive factors for high mortality in hypernatremic patients. Am J Emerg Med 1997; 15: 130-132.
26. Erasmus RT, Matsua TE,. Frequency, aetiology and outcome of hypernatraemia in hospitalised patients in Umtata, Transkei, South Africa. East Afr Med J 1999; 76: 85-88.
27. O'Donoghue SD, Dulhunty JM, Bandeshe HK, Senthuran S, Gowardman JR,. Acquired hypernatraemia is an independent predictor of mortality in critically ill patients. Anaesthesia 2009; 64: 514-520.
28. Bagshaw SM, Townsend DR, McDermid RC,. Disorders of sodium and water balance in hospitalized patients. Can J Anaesth 2009; 56: 151-167.
29. Nelson DC, McGrew WR Jr, Hoyumpa AM Jr,. Hypernatremia and lactulose therapy. JAMA 1983; 249: 1295-1298.
30. Rodés J, Arroyo V, Bordas JM, Bruguera M,. Hypernatremia following gastrointestinal bleeding in cirrhosis with ascites. Am J Dig Dis 1975; 20: 127-133.
31. Polderman KH, Schreuder WO, Strack van Schijndel RJ, Thijs LG,. Hypernatremia in the intensive care unit: an indicator of quality of care? Crit Care Med 1999; 27: 1105-1108.
32. Cywinski JB, Mascha E, Miller C, Eghtesad B, Nakagawa S, Vincent JP, et al. Association between donor-recipient serum sodium differences and orthotopic liver transplant graft function. Liver Transpl 2008; 14: 59-65. Kidney Diseases Diseases