A randomized controlled trial of the effectiveness of computer-assisted cognitive remediation (CACR) in adolescents with psychosis or at high risk of psychosis

Behavioural and Cognitive Psychotherapy

Volumn 42, Issue 4, 2014, Pages 421-434

  Holzer, Laurent ^a   Urben, Sebastien ^a   Passini, Christina Moses ^a   Jaugey, Laure ^a   Herzog, Michael H ^b   Halfon, Olivier ^c   Pihet, Sandrine ^c  

^a Centre Thérapeutique de Jour Pour Adolescents   (Switzerland)

^b EPFL   (Switzerland)

^c LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

adolescent; cognitive remediation; computer; controlled trial; Psychosis

Indexed keywords

ADOLESCENT; COGNITION DISORDERS; COGNITIVE THERAPY; COMPUTER ASSISTED THERAPY; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; HUMAN; INTENTION TO TREAT ANALYSIS; MALE; NEUROPSYCHOLOGICAL TEST; PROCEDURES; PSYCHOLOGICAL RATING SCALE; PSYCHOLOGY; PSYCHOMETRY; PSYCHOTIC DISORDERS; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; SCHIZOTYPAL PERSONALITY DISORDER; STATISTICS AND NUMERICAL DATA; TEACHING;

ADOLESCENT; COGNITION DISORDERS; COGNITIVE THERAPY; DOUBLE-BLIND METHOD; HUMANS; INTENTION TO TREAT ANALYSIS; MALE; NEUROPSYCHOLOGICAL TESTS; PSYCHIATRIC STATUS RATING SCALES; PSYCHOMETRICS; PSYCHOTIC DISORDERS; REMEDIAL TEACHING; RISK FACTORS; SCHIZOTYPAL PERSONALITY DISORDER; THERAPY, COMPUTER-ASSISTED;

EID: 84901399210     PISSN: 13524658     EISSN: 14691833     Source Type: Journal    
DOI: 10.1017/S1352465813000313     Document Type: Article

References (30)

1. Anderson, C. A. (2004). An update on the effects of playing violent video games. Journal of Adolescence, 27, 113-122.
2. APA (1994). Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) (4th edn.). Washington, DC: American Psychiatric Association.
3. Bellucci, D. M., Glaberman, K. and Haslam, N. (2003). Computer-assisted cognitive rehabilitation reduces negative symptoms in the severely mentally ill. Schizophrenia Research, 59, 225-232.
4. Bremer, J. and Rauch, P. K. (1998). Children and computers: Risks and benefits. Journal of the American Academy of Child and Adolescent Psychiatry, 37, 559-560.
5. Choi, J. andMedalia, A. (2009). Intrinsic motivation and learning in a schizophrenia spectrum sample. Schizophrenia Research, 118, 12-19.
6. Cohen, J. (1992). A power primer. Psychological Bulletin, 112, 155-159.
7. Eack, S. M., Greenwald, D. P., Hogarty, S. S., Cooley, S. J., DiBarry, A. L., Montrose, D. M., et al. (2009). Cognitive enhancement therap y for early-course schizophrenia: Effects of a two-year randomized controlled trial. Psychiatric Services, 60, 1468-1476.
8. Eack, S. M., Hogarty, G. E., Cho, R. Y., Prasad, K. M., Greenwald, D. P., Hogarty , S. S., et al. (2010). Neuroprotective effects of cognitive enhancement therapy against gray matter loss in early schizophrenia: Results from a 2-year randomized controlled trial. Archives of General Psychiatry, 67, 674-682.
9. Gowers, S. G., Harrington, R. C., Whitton, A., Lelliott, P., Beevor, A., Wing, J., et al. (1999). Brief scale for measuring the outcomes of emotional and behavioural disorders in children. Health of the Nation Outcom e Scales for Children and Adolescents (HoNOSCA). The British Journal of Psychiatry, 174, 413-416.
10. Grynszpan, O., Perbal, S., Pelissolo, A., Fossati, P., Jouvent, R., Dubal, S., et al. (2011). Ef ficacy and specificity of computer-assisted cognitive remediation in schizophrenia: A meta-analytical study. Psychological Medecine, 41, 163-173.
11. Hogarty G. E. Flesher S. Ulrich R. Carter M. Greenwald D. Pogue-Geile, M. et al. 2004 Cognitive enhancement therapy for schizophrenia: Effects of a 2-year randomized trial on cognition and behavior Archives of General Psychiatry 61 866-876.
12. Holzer, L., Chinet, L., Jaugey, L., Plancherel, B., Sofia, C., Halfon, O., et al. (2007). Detection of cognitive impairment with the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) in ado lescents with psychotic symptomatology. Schizophrenia Research, 95, 48-53.
13. Howell, D. C. (2008). The treatment of missing data. In W. Outhwaite and S. Turner (Eds.), Handbook of Social Science Methodology (pp. 208-224). London: Sage.
14. Kay, S. R., Fiszbein, A. and Opler, L. A. (1987). The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophrenia Bulletin, 13, 261-276.
15. Keefe, R. S., Vinogradov, S., Medalia, A., Silverstein, S.M., Bell,M. D., Dickinson, D., et al. (2011). Report from the working group conference on multisite trial design for cognitive remediation in schizophrenia. Schizophrenia Bulleti n, 37, 1057-1065.
16. Kurtz, M. M., Seltzer, J. C., Shagan, D. S., Thime, W. R. and Wexler, B. E. (2007). Computerassisted cognitive remediation in schizophrenia: What is the active ingredient Schizophrenia Research, 89, 251-260.
17. McGurk, S. R., Twamley, E. W., Sitzer, D. I., McHugo, G. J. and Mueser, K. T. (2007). A metaanalysis of cognitive remediation in schizophrenia. The American Journal of Psychiatry, 164, 1791-1802.
18. Medalia, A., Aluma, M., Tryon,W. and Merriam, A. E. (1998). Effectiveness of attention training in schizophrenia. Schizophrenia Bulletin, 24, 147-152.
19. Medalia, A. and Richardson, R. (2005). What predicts a good response to cognitive remediation interventions Schizophrenia Bulletin, 31, 942-953.
20. Miller, T. J., McGlashan, T. H., Woods, S. W., Stein, K., Driesen, N., Corcoran, C. M., et al. (1999). Symptom assessment in schizophrenic prodromal states. The Psychiatric Quarterly, 70, 273-287.
21. Nurnberger, J. I., Blehar, M. C., Kaufmann, C. A., Y orkcooler, C., Simpson, S. G., Harkavyfriedman, J., et al. (1994). Diagnostic Interview for Genetic-Studies: Rationale, unique features, and training. Archives of General Psychiatry, 51, 849-859.
22. Palmer , B. W., Dawes, S. E. and Heaton, R. K. (2009). What do we know about neuropsychological aspects of schizophrenia Neuropsychology Review, 19, 365-384.
23. Preisig, M., Fenton, B. T., Matthey, M. L., Berney, A. and Ferrero, F. (1999). Diagnostic Interview for Genetic Studies (DIGS): Inter-rater and test-retest reliability of the French version. European Archives of Psychiatry and Clinical Neuroscience, 249, 174-179.
24. Randolph, C., Tierney, M. C., Mohr, E. and Chase, T. N. (1998). The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS): Preliminary clinical validity. Journal of Clinical and Experimental Neurop sychology, 20, 310-319.
25. Sanford, J. A. and Brown, R. J. (1988). Captain s Log Cognitive System. Richmond, VA: Brain Train, Inc.
26. Ueland, T. and Rund, B. R. (2004). A controlled randomized treatment study: The effects of a cognitive remediation program on adolescents with early onset psychosis. Acta Psychiatrica Scandinavica, 109, 70-74.
27. Uhlmann, E. and Swanson, J. (2004). Exposure to violent video games increases automatic aggressiveness. Journal of Adolescence, 27, 41-52.
28. Urben, S., Pihet, S., Jaugey, L., Halfon, O. and Holzer, L. (2012). C omputer-assisted cognitive remediation in adolescents with psychosis or at risk for psychosis: A 6-month follow-up. Acta Neuropsychiatrica, 24, 328-335.
29. Wykes, T., Huddy, V., Cellard, C., McGurk, S. R. and Czobor, P. (2011). A meta-analysis of cognitive remediation for schizophrenia: Methodology and effect sizes. The American Journal of Psychiatry, 168, 472-485.
30. Wykes, T., Reeder, C., Corner, J., Williams, C. and Everitt, B. T. (1999). The effects of neurocognitive remediation on executive processing in patients with schizophrenia. Schizophrenia Bulletin, 25, 291-307.