Dysregulated miR-361-5p/VEGF axis in the plasma and endothelial progenitor cells of patients with coronary artery disease

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Wang, Hsei Wei ^a,b   Lo, Hung Hao ^a   Chiu, Ya Lin ^a   Chang, Shing Jyh ^c   Huang, Po Hsun ^a,d   Liao, Ko Hsun ^a   Tasi, Cheng Fong ^a   Wu, Chun Hsien ^e   Tsai, Tsung Neng ^e   Cheng, Cheng Chung ^e   Cheng, Shu Meng ^e  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b TAIPEI CITY HOSPITAL   (Taiwan)

^c MACKAY MEMORIAL HOSPITAL   (Taiwan)

^d TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^e TRI SERVICE GENERAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 361 5P; MICRORNA 484; UNCLASSIFIED DRUG; VASCULOTROPIN; MESSENGER RNA; MIRN361 MICRORNA, HUMAN; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

3' UNTRANSLATED REGION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; CELL ACTIVITY; CONTROLLED STUDY; CORONARY ARTERY DISEASE; ENDOTHELIAL PROGENITOR CELL; GENE REPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIMB BLOOD FLOW; LIMB ISCHEMIA; MOUSE; NONHUMAN; PLASMA CELL; PROTEIN EXPRESSION; PROTEIN TARGETING; RNA SEQUENCE; ANGIOGENESIS; ANIMAL; APOPTOSIS; BLOOD; CASE CONTROL STUDY; CELL CULTURE; CELL MOTION; CELL PROLIFERATION; ENZYME IMMUNOASSAY; GENETICS; ISCHEMIA; METABOLISM; NUDE MOUSE; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; APOPTOSIS; CASE-CONTROL STUDIES; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; CORONARY ARTERY DISEASE; ENDOTHELIAL PROGENITOR CELLS; HUMANS; IMMUNOENZYME TECHNIQUES; ISCHEMIA; MICE; MICE, NUDE; MICRORNAS; NEOVASCULARIZATION, PHYSIOLOGIC; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84901394422     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0098070     Document Type: Article

References (50)

1. Werner N, Kosiol S, Schiegl T, Ahlers P, Walenta K, et al. (2005) Circulating endothelial progenitor cells and cardiovascular outcomes. N Engl J Med 353: 999-1007. (Pubitemid 41262334)
2. Grisar JC, Haddad F, Gomari FA, Wu JC (2011) Endothelial progenitor cells in cardiovascular disease and chronic inflammation: from biomarker to therapeutic agent. Biomark Med 5: 731-744.
3. Asahara T, Murohara T, Sullivan A, Silver M, van der Zee R, et al. (1997) Isolation of putative progenitor endothelial cells for angiogenesis. Science 275: 964-967. (Pubitemid 27087709)
4. Reyes M, Dudek A, Jahagirdar B, Koodie L, Marker PH, et al. (2002) Origin of endothelial progenitors in human postnatal bone marrow. J Clin Invest 109: 337-346. (Pubitemid 34141807)
5. Real C, Caiado F, Dias S (2008) Endothelial progenitors in vascular repair and angiogenesis: how many are needed and what to do? Cardiovasc Hematol Disord Drug Targets 8: 185-193.
6. Briguori C, Testa U, Riccioni R, Colombo A, Petrucci E, et al. (2010) Correlations between progression of coronary artery disease and circulating endothelial progenitor cells. Faseb J 24: 1981-1988.
7. Briasoulis A, Tousoulis D, Antoniades C, Stefanadis C, Papageorgiou N (2010) The Role of Endothelial Progenitor Cells in Vascular Repair after Arterial Injury and Atherosclerotic Plaque Development. Cardiovasc Ther.
8. Smythe J, Fox A, Fisher N, Frith E, Harris AL, et al. (2008) Measuring angiogenic cytokines, circulating endothelial cells, and endothelial progenitor cells in peripheral blood and cord blood: VEGF and CXCL12 correlate with the number of circulating endothelial progenitor cells in peripheral blood. Tissue Eng Part C Methods 14: 59-67. (Pubitemid 351520452)
9. Yu J, Wang A, Tang Z, Henry J, Li-Ping Lee B, et al. (2012) The effect of stromal cell-derived factor-1alpha/heparin coating of biodegradable vascular grafts on the recruitment of both endothelial and smooth muscle progenitor cells for accelerated regeneration. Biomaterials 33: 8062-8074.
10. Yamaguchi J, Kusano KF, Masuo O, Kawamoto A, Silver M, et al. (2003) Stromal cell-derived factor-1 effects on ex vivo expanded endothelial progenitor cell recruitment for ischemic neovascularization. Circulation 107: 1322-1328. (Pubitemid 36314418)
11. Iwaguro H, Yamaguchi J, Kalka C, Murasawa S, Masuda H, et al. (2002) Endothelial progenitor cell vascular endothelial growth factor gene transfer for vascular regeneration. Circulation 105: 732-738. (Pubitemid 34157378)
12. Cheng CC, Lo HH, Huang TS, Cheng YC, Chang ST, et al. (2012) Genetic module and miRNome trait analyses reflect the distinct biological features of endothelial progenitor cells from different anatomic locations. BMC Genomics 13: 447.
13. Peichev M, Naiyer AJ, Pereira D, Zhu Z, Lane WJ, et al. (2000) Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors. Blood 95: 952-958. (Pubitemid 30062717)
14. Badran A, Yoshida A, Ishikawa K, Goi T, Yamaguchi A, et al. (2004) Identification of a novel splice variant of the human anti-apoptopsis gene survivin. Biochem Biophys Res Commun 314: 902-907. (Pubitemid 38112885)
15. Melero-Martin JM, Khan ZA, Picard A, Wu X, Paruchuri S, et al. (2007) In vivo vasculogenic potential of human blood-derived endothelial progenitor cells. Blood 109: 4761-4768. (Pubitemid 46827769)
16. Guay C, Regazzi R (2013) Circulating microRNAs as novel biomarkers for diabetes mellitus. Nat Rev Endocrinol 9: 513-521.
17. Dang LT, Lawson ND, Fish JE (2013) MicroRNA control of vascular endothelial growth factor signaling output during vascular development. Arterioscler Thromb Vasc Biol 33: 193-200.
18. Yin KJ, Olsen K, Hamblin M, Zhang J, Schwendeman SP, et al. (2012) Vascular endothelial cell-specific microRNA-15a inhibits angiogenesis in hindlimb ischemia. J Biol Chem 287: 27055-27064.
19. Wang R, Zhao N, Li S, Fang JH, Chen MX, et al. (2013) MicroRNA-195 suppresses angiogenesis and metastasis of hepatocellular carcinoma by inhibiting the expression of VEGF, VAV2, and CDC42. Hepatology 58: 642-653.
20. Cheng WC, Chung IF, Huang TS, Chang ST, Sun HJ, et al. (2013) YM500: a small RNA sequencing (smRNA-seq) database for microRNA research. Nucleic Acids Res 41: D285-D294.
21. Chen C, Ridzon DA, Broomer AJ, Zhou Z, Lee DH, et al. (2005) Real-time quantification of microRNAs by stem-loop RT-PCR. Nucleic Acids Res 33: e179.
22. Huang PH, Chen CY, Lin CP, Wang CH, Tsai HY, et al. (2013) Deletion of FHL2 gene impaired ischemia-induced blood flow recovery by modulating circulating proangiogenic cells. Arterioscler Thromb Vasc Biol 33: 709-717.
23. Chen YH, Lin SJ, Lin FY, Wu TC, Tsao CR, et al. (2007) High glucose impairs early and late endothelial progenitor cells by modifying nitric oxide-related but not oxidative stress-mediated mechanisms. Diabetes 56: 1559-1568.
24. Hsu JB, Chiu CM, Hsu SD, Huang WY, Chien CH, et al. (2011) miRTar: an integrated system for identifying miRNA-target interactions in human. BMC Bioinformatics 12: 300.
25. Liu H, Yue D, Chen Y, Gao SJ, Huang Y (2010) Improving performance of mammalian microRNA target prediction. BMC Bioinformatics 11: 476.
26. Kumar B, Yadav A, Lang J, Teknos TN, Kumar P (2012) Dysregulation of microRNA-34a expression in head and neck squamous cell carcinoma promotes tumor growth and tumor angiogenesis. PLoS One 7: e37601.
27. Tabuchi T, Satoh M, Itoh T, Nakamura M (2012) MicroRNA-34a regulates the longevity-associated protein SIRT1 in coronary artery disease: effect of statins on SIRT1 and microRNA-34a expression. Clin Sci (Lond) 123: 161-171.
28. Szczyrba J, Nolte E, Hart M, Doll C, Wach S, et al. (2013) Identification of ZNF217, hnRNP-K, VEGF-A and IPO7 as targets for microRNAs that are downregulated in prostate carcinoma. Int J Cancer 132: 775-784.
29. Zampetaki A, Kiechl S, Drozdov I, Willeit P, Mayr U, et al. (2010) Plasma microRNA profiling reveals loss of endothelial miR-126 and other microRNAs in type 2 diabetes. Circ Res 107: 810-817.
30. Zhou B, Ma R, Si W, Li S, Xu Y, et al. (2013) MicroRNA-503 targets FGF2 and VEGFA and inhibits tumor angiogenesis and growth. Cancer Lett 333: 159-169.
31. Caporali A, Meloni M, Vollenkle C, Bonci D, Sala-Newby GB, et al. (2011) Deregulation of microRNA-503 contributes to diabetes mellitus-induced impairment of endothelial function and reparative angiogenesis after limb ischemia. Circulation 123: 282-291.
32. Mobius-Winkler S, Hollriegel R, Schuler G, Adams V (2009) Endothelial progenitor cells: implications for cardiovascular disease. Cytometry A 75: 25-37.
33. Asahara T, Takahashi T, Masuda H, Kalka C, Chen D, et al. (1999) VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells. EMBO J 18: 3964-3972. (Pubitemid 29335849)
34. Vasa M, Fichtlscherer S, Aicher A, Adler K, Urbich C, et al. (2001) Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ Res 89: E1-7.
35. Li D, Yang P, Xiong Q, Song X, Yang X, et al. (2010) MicroRNA-125a/b-5p inhibits endothelin-1 expression in vascular endothelial cells. J Hypertens 28: 1646-1654.
36. Vecchione A, Belletti B, Lovat F, Volinia S, Chiappetta G, et al. (2013) A microRNA signature defines chemoresistance in ovarian cancer through modulation of angiogenesis. Proc Natl Acad Sci U S A 110: 9845-9850.
37. Cho HJ, Kim HS, Lee MM, Kim DH, Yang HJ, et al. (2003) Mobilized endothelial progenitor cells by granulocyte-macrophage colony-stimulating factor accelerate reendothelialization and reduce vascular inflammation after intravascular radiation. Circulation 108: 2918-2925.
38. Walter DH, Rittig K, Bahlmann FH, Kirchmair R, Silver M, et al. (2002) Statin therapy accelerates reendothelialization: a novel effect involving mobilization and incorporation of bone marrow-derived endothelial progenitor cells. Circulation 105: 3017-3024. (Pubitemid 34693836)
39. Heissig B, Hattori K, Dias S, Friedrich M, Ferris B, et al. (2002) Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand. Cell 109: 625-637. (Pubitemid 34628725)
40. Heissig B, Werb Z, Rafii S, Hattori K (2003) Role of c-kit/Kit ligand signaling in regulating vasculogenesis. Thromb Haemost 90: 570-576. (Pubitemid 37287623)
41. Minami Y, Satoh M, Maesawa C, Takahashi Y, Tabuchi T, et al. (2009) Effect of atorvastatin on microRNA 221/222 expression in endothelial progenitor cells obtained from patients with coronary artery disease. Eur J Clin Invest 39: 359-367.
42. Zhang Q, Kandic I, Kutryk MJ (2011) Dysregulation of angiogenesis-related microRNAs in endothelial progenitor cells from patients with coronary artery disease. Biochem Biophys Res Commun 405: 42-46.
43. Poliseno L, Tuccoli A, Mariani L, Evangelista M, Citti L, et al. (2006) MicroRNAs modulate the angiogenic properties of HUVECs. Blood 108: 3068-3071.
44. Fichtlscherer S, De Rosa S, Fox H, Schwietz T, Fischer A, et al. (2010) Circulating microRNAs in patients with coronary artery disease. Circ Res 107: 677-684.
45. Hulsmans M, Holvoet P (2013) MicroRNA-containing microvesicles regulating inflammation in association with atherosclerotic disease. Cardiovasc Res 100: 7-18.
46. Turchinovich A, Weiz L, Langheinz A, Burwinkel B (2011) Characterization of extracellular circulating microRNA. Nucleic Acids Res 39: 7223-7233.
47. Arroyo JD, Chevillet JR, Kroh EM, Ruf IK, Pritchard CC, et al. (2011) Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma. Proc Natl Acad Sci U S A 108: 5003-5008.
48. Record M, Subra C, Silvente-Poirot S, Poirot M (2011) Exosomes as intercellular signalosomes and pharmacological effectors. Biochem Pharmacol 81: 1171-1182.
49. Mocharla P, Briand S, Giannotti G, Dorries C, Jakob P, et al. (2013) AngiomiR- 126 expression and secretion from circulating CD34(+) and CD14(+) PBMCs: role for proangiogenic effects and alterations in type 2 diabetics. Blood 121: 226-236.
50. Azmi AS, Bao B, Sarkar FH (2013) Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review. Cancer Metastasis Rev 32: 623-642.