Quantification of intact human insulin-like growth factor-I in serum by nano-ultrahigh-performance liquid chromatography/tandem mass spectrometry

Rapid Communications in Mass Spectrometry

Volumn 28, Issue 13, 2014, Pages 1426-1432

  Lopes, Filipe ^a   Cowan, David A ^a   Thevis, Mario ^b   Thomas, Andreas ^b   Parkin, Mark C ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b GERMAN SPORT UNIVERSITY COLOGNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMARKERS; BODY FLUIDS; ELECTROSPRAY IONIZATION; ENDOCRINOLOGY; HORMONES; LABORATORIES; LIQUID CHROMATOGRAPHY; PEPTIDES; PRECIPITATION (CHEMICAL);

CURRENT TESTING; GROWTH FACTOR; GROWTH HORMONES; HUMAN INSULINS; HUMAN SERUM; INSULIN-LIKE GROWTH FACTOR-I; SAMPLE VOLUME; SERUM SAMPLES; ULTRA-HIGH PERFORMANCE LIQUID CHROMATOGRAPHY/TANDEM MASS SPECTROMETRIES; ULTRAHIGH PERFORMANCE LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRIES;

MASS SPECTROMETRY;

SOMATOMEDIN C;

ANIMAL; CALIBRATION; DEVICES; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; NANOTECHNOLOGY; PROCEDURES; RAT; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; STATISTICAL MODEL; TANDEM MASS SPECTROMETRY;

ANIMALS; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; INSULIN-LIKE GROWTH FACTOR I; LINEAR MODELS; NANOTECHNOLOGY; RATS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 84901392298     PISSN: 09514198     EISSN: 10970231     Source Type: Journal    
DOI: 10.1002/rcm.6908     Document Type: Article

References (27)

1. J. M. Street, J. W. Dear,. The application of mass-spectrometry-based protein biomarker discovery to theragnostics. Br. J. Clin. Pharmacol. 2010, 69, 367.
2. T. B. Schaaij-Visser, R. H. Brakenhoff, C. R. Leemans, A. J. Heck, M. Slijper,. Protein biomarker discovery for head and neck cancer. J. Proteomics 2010, 73, 1790.
3. L. A. Liotta, E. F. Petricoin,. Mass spectrometry-based protein biomarker discovery: solving the remaining challenges to reach the promise of clinical benefit. Clin. Chem. 2010, 56, 1641.
4. A. E. Rigamonti, S. G. Cella, N. Marazzi, L. Di Luigi, A. Sartorio, E. E. Muller,. Growth hormone abuse: methods of detection. Trends Endocrinol. Metab. 2005, 16, 160.
5. A. E. Nelson, K. K. Ho,. A robust test for growth hormone doping-present status and future prospects. Asian J. Androl. 2008, 10, 416.
6. P. H. Sonksen,. Insulin, growth hormone and sport. J. Endocrinol. 2001, 170, 13.
7. A. N. Hoofnagle, M. H. Wener,. The fundamental flaws of immunoassays and potential solutions using tandem mass spectrometry. J. Immunol. Methods 2009, 347, 3.
8. M. Bidlingmaier,. Pitfalls of insulin-like growth factor I assays. Horm. Res. 2009, 71 Suppl 1, 30.
9. R. E. Chestnut, V. Quarmby,. Evaluation of total IGF-I assay methods using samples from type I and type II diabetic patients. J. Immunol. Methods 2002, 259, 11.
10. M. Thevis, W. Schanzer,. Mass spectrometric identification of peptide hormones in doping-control analysis. Analyst 2007, 132, 287.
11. M. Thevis, A. Thomas, W. Schanzer,. Doping control analysis of selected peptide hormones using LC-MS(/MS). Forensic Sci. Int. 2011, 213, 35.
12. M. A. Popot, A. R. Woolfitt, P. Garcia, J. C. Tabet,. Determination of IGF-I in horse plasma by LC electrospray ionisation mass spectrometry. Anal. Bioanal. Chem. 2008, 390, 1843.
13. R. G. Kay, C. Barton, C. P. Velloso, P. R. Brown, C. Bartlett, A. J. Blazevich, R. J. Godfrey, G. Goldspink, R. Rees, G. R. Ball, D. A. Cowan, S. D. Harridge, J. Roberts, P. Teale, C. S. Creaser,. High-throughput ultra-high-performance liquid chromatography/tandem mass spectrometry quantitation of insulin-like growth factor-I and leucine-rich α-2-glycoprotein in serum as biomarkers of recombinant human growth hormone administration. Rapid Commun. Mass Spectrom. 2009, 23, 3173.
14. O. Barroso, D. J. Handelsman, C. Strasburger, M. Thevis,. Analytical challenges in the detection of peptide hormones for anti-doping purposes. Bioanalysis 2012, 4, 1577.
15. J. S. Page, R. T. Kelly, K. Tang, R. D. Smith,. Ionization and transmission efficiency in an electrospray ionization-mass spectrometry interface. J. Am. Soc. Mass Spectrom. 2007, 18, 1582.
16. C. N. Ryan, K. L. Smith, M. S. Alexander, J. P. W. Stark,. Effect of emitter geometry on flow rate sensitivity to voltage in cone jet mode electrospray. J. Phys. D: Appl. Phys. 2009, 42, 155504.
17. R. T. Kelly, J. S. Page, Q. Luo, R. J. Moore, D. J. Orton, K. Tang, R. D. Smith,. Chemically etched open tubular and monolithic emitters for nanoelectrospray ionisation mass spectrometry. Anal. Chem. 2006, 78, 7796.
18. M. Bredehoft, W. Schanzer, M. Thevis,. Quantification of human insulin-like growth factor-1 and qualitative detection of its analogues in plasma using liquid chromatography/electrospray ionisation tandem mass spectrometry. Rapid Commun. Mass Spectrom. 2008, 22, 477.
19. P. Shipkova, D. M. Drexler, R. Langish, J. Smalley, M. E. Salyan, M. Sanders,. Application of ion trap technology to liquid chromatography/mass spectrometry quantitation of large peptides. Rapid Commun. Mass Spectrom. 2008, 22, 1359.
20. S. S. Bansal, V. Abbate, A. Bomford, J. M. Halket, I. C. Macdougall, S. L. Thein, R. C. Hider,. Quantitation of hepcidin in serum using ultra-high-pressure liquid chromatography and a linear ion trap mass spectrometer. Rapid Commun. Mass Spectrom. 2010, 24, 1251.
21. A. Thomas, W. Schanzer, P. Delahaut, M. Thevis,. Immunoaffinity purification of peptide hormones prior to liquid chroamtography-mass spectrometry in doping controls. Methods 2012, 56, 230.
22. C. E. Bystrom, S. Sheng, N. J. Clarke,. Narrow mass extraction time-of-flight data for quantitative analysis of proteins: Determination of insulin-like growth factor-1. Anal. Chem. 2011, 83, 9005.
23. P. Schuck,. Use of surface plasmon resonance to probe the equilibrium and dynamic aspects of interactions between biological macromolecules. Annu. Rev. Biophys. Biomol. Struct. 1997, 26, 541.
24. H. N. Daghestani, B. W. Day,. Theory and applications of surface plasmon resonance, resonant mirror, resonant waveguide grating, and dual polarization interferometry biosensors. Sensors (Basel) 2010, 10, 9630.
25. H. D. Cox, F. Lopes, G. A. Woldemariam, J. O. Becker, M. C. Parkin, A. Thomas, A. W. Butch, D. A. Cowan, M. Thevis, L. D. Bowers, A. N. Hoofnagle,. Interlaboratory agreement of Insulin-like growth factor 1 concentrations measured by mass spectrometry. Clin. Chem. 2014, 60, 541.
26. T. Porstmann, B. Porstmann, B. Micheel, E. H. Schmidt, H. Herzmann,. Characterization by Scatchard plots of monoclonal antibody enzyme conjugates directed against alpha-1-foetoprotein. J. Immunol. Methods 1984, 66, 277.
27. R. K. Boyd, C. Basic, R. A. Bethem,. Trace Quantitative Analysis by Mass Spectrometry. John Wiley, Chichester, 2008.