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Volumn 2, Issue 4, 2012, Pages 1455-1459

Improved synthesis and crystal structure of dalcetrapib

Author keywords

CETP inhibitor; Dalcetrapib; Disulfide; Thioester

Indexed keywords


EID: 84901372954     PISSN: None     EISSN: 20734352     Source Type: Journal    
DOI: 10.3390/cryst2041455     Document Type: Article
Times cited : (3)

References (11)
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    • Shinkai, H.; Maeda, K.; Yamasaki, T.; Okamoto, H.; Uchida, I. Bis(2-(Acylamino)phenyl) disulfides, 2-(acylamino)benzenethiols, and S-(2-(acylamino)phenyl) alkanethioates as novel inhibitors of cholesteryl ester transfer protein. J. Med. Chem. 2000, 43, 3566-3572.
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    • Cholesteryl ester transfer-protein modulator and inhibitors and their potential for the treatment of cardiovascular diseases
    • Shinkai, H. Cholesteryl ester transfer-protein modulator and inhibitors and their potential for the treatment of cardiovascular diseases. Vasc. Health Risk Manag. 2012, 8, 323-331.
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    • Shinkai, H.1
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    • Vascular effects and safety of dalcetrapib in patients with or at risk of coronary heart disease: The dal-VESSEL randomized clinical trial
    • Luescher, T.F.; Taddei, S.; Kaski, J.-C.; Jukema, J.W.; Kallend, D.; Muenzel, T.; Kastelein, J.J.P.; Deanfield, J.E. Vascular effects and safety of dalcetrapib in patients with or at risk of coronary heart disease: The dal-VESSEL randomized clinical trial. Eur. Heart J. 2012, 33, 857-865.
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    • Luescher, T.F.1    Taddei, S.2    Kaski, J.-C.3    Jukema, J.W.4    Kallend, D.5    Muenzel, T.6    Kastelein, J.J.P.7    Deanfield, J.E.8
  • 7
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    • Sridhar, M.; Vadivel, S.K.; Bhalerao, U.T. Reduction of symmetric disulfides to thiols using Mg in methanol. Synth. Commun. 1997, 27, 1347-1350.
    • (1997) Synth. Commun. , vol.27 , pp. 1347-1350
    • Sridhar, M.1    Vadivel, S.K.2    Bhalerao, U.T.3
  • 8
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    • Dithiothreitol, a new protective reagent for SH groups
    • Cleland, W.W. Dithiothreitol, a new protective reagent for SH groups. Biochemistry 1964, 3, 480-482.
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  • 10
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    • Dynamic covalent chemistry of disulfides offers a highly efficient synthesis of diverse benzofused nitrogen-sulfur heterocycles in one pot
    • Zhu, N.; Zhang, F.; Liu, G. Dynamic covalent chemistry of disulfides offers a highly efficient synthesis of diverse benzofused nitrogen-sulfur heterocycles in one pot. J. Comb. Chem. 2010, 12, 531-540.
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    • Zhu, N.1    Zhang, F.2    Liu, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.