-
1
-
-
39149104690
-
Meta-analysis of phase II cooperative group trials in metastatic stage IV melanoma to determine progression-free and overall survival benchmarks for future phase II trials
-
Korn EL, Liu PY, Lee SJ, et al. Meta-analysis of phase II cooperative group trials in metastatic stage IV melanoma to determine progression-free and overall survival benchmarks for future phase II trials. J Clin Oncol. 2008; 26: 527-534.
-
(2008)
J Clin Oncol.
, vol.26
, pp. 527-534
-
-
Korn, E.L.1
Liu, P.Y.2
Lee, S.J.3
-
2
-
-
84868224906
-
Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations
-
Flaherty KT, Infante JR, Daud A, et al. Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations. N Engl J Med. 2012; 367: 1694-1703.
-
(2012)
N Engl J Med.
, vol.367
, pp. 1694-1703
-
-
Flaherty, K.T.1
Infante, J.R.2
Daud, A.3
-
3
-
-
84879777241
-
Nivolumab plus ipilimumab in advanced melanoma
-
Wolchok JD, Kluger H, Callahan MK, et al. Nivolumab plus ipilimumab in advanced melanoma. N Engl J Med. 2013; 369: 122-133.
-
(2013)
N Engl J Med.
, vol.369
, pp. 122-133
-
-
Wolchok, J.D.1
Kluger, H.2
Callahan, M.K.3
-
4
-
-
84875785905
-
Hepatotoxicity with combination of vemurafenib and ipilimumab
-
Ribas A, Hodi FS, Callahan M, et al. Hepatotoxicity with combination of vemurafenib and ipilimumab. N Engl J Med. 2013; 368: 1365-1366.
-
(2013)
N Engl J Med.
, vol.368
, pp. 1365-1366
-
-
Ribas, A.1
Hodi, F.S.2
Callahan, M.3
-
5
-
-
84861450830
-
Sequencing of BRAFinhibitors and ipilimumab in patients with metastatic melanoma: A possible algorithm for clinical use
-
Ascierto PA, Simeone E, Giannarelli D, et al. Sequencing of BRAFinhibitors and ipilimumab in patients with metastatic melanoma: a possible algorithm for clinical use. J Transl Med. 2012; 10: 107.
-
(2012)
J Transl Med.
, vol.10
, pp. 107
-
-
Ascierto, P.A.1
Simeone, E.2
Giannarelli, D.3
-
6
-
-
84874708193
-
Do BRAF inhibitors select for populations with different disease progression kinetics?
-
Ascierto PA, Simeone E, Grimaldi AM, et al. Do BRAF inhibitors select for populations with different disease progression kinetics? J Transl Med. 2013; 11: 61
-
(2013)
J Transl Med.
, vol.11
, pp. 61
-
-
Ascierto, P.A.1
Simeone, E.2
Grimaldi, A.M.3
-
7
-
-
84901340078
-
Outcomes of patients with metastatic melanoma treated with immunotherapy prior to or after BRAF inhibitors
-
Ackerman A, Klein O, McDermott DF, et al. Outcomes of patients with metastatic melanoma treated with immunotherapy prior to or after BRAF inhibitors. Cancer. 2014; 120: 1695-1701.
-
(2014)
Cancer.
, vol.120
, pp. 1695-1701
-
-
Ackerman, A.1
Klein, O.2
McDermott, D.F.3
-
8
-
-
84901360357
-
-
Updated October. Available at:. Accessed November 2013
-
European Commission-Community Register of Medicinal Products. Updated October 2013. Available at: http://ec.europa.eu/health/documents/community- register/html/h698.htm. Accessed November 2013.
-
(2013)
European Commission - Community Register of Medicinal Products
-
-
-
9
-
-
75249100054
-
Ipilimumab monotherapy in patients with pretreated advanced melanoma: A randomised, double-blind, multicentre, phase 2, dose-ranging study
-
Wolchok JD, Neyns B, Linette G, et al. Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study. Lancet Oncol. 2010; 11: 155-164.
-
(2010)
Lancet Oncol.
, vol.11
, pp. 155-164
-
-
Wolchok, J.D.1
Neyns, B.2
Linette, G.3
-
10
-
-
84874825359
-
The European ipilimumab Expanded Access Programme (EAP): Efficacy and safety data from the Italian cohort of patients with pretreated, advanced melanoma
-
Ascierto PA, Chiarion Sileni V, Del Vecchio M, et al. The European ipilimumab Expanded Access Programme (EAP): efficacy and safety data from the Italian cohort of patients with pretreated, advanced melanoma. Ann Oncol. 2012; 23 (suppl 9): ix367-ix375.
-
(2012)
Ann Oncol.
, vol.23
, Issue.SUPPL. 9
-
-
Ascierto, P.A.1
Chiarion Sileni, V.2
Del Vecchio, M.3
-
11
-
-
84876678621
-
Patterns of onset and resolution of immune-related adverse events of special interest with ipilimumab: Detailed safety analysis from a phase 3 trial in patients with advanced melanoma
-
MDX010-20 Investigators.
-
Weber JS, Dummer R, de Pril V, et al; MDX010-20 Investigators. Patterns of onset and resolution of immune-related adverse events of special interest with ipilimumab: detailed safety analysis from a phase 3 trial in patients with advanced melanoma. Cancer. 2013; 119: 1675-1682.
-
(2013)
Cancer.
, vol.119
, pp. 1675-1682
-
-
Weber, J.S.1
Dummer, R.2
De Pril, V.3
-
12
-
-
84891274874
-
Sequential treatment with ipilimumab and BRAF inhibitors in patients with metastatic melanoma: Data from the Italian cohort of ipilimumab expanded access programme (EAP)
-
abstract 9035.
-
Ascierto PA, Simeone E, Chiarion-Sileni V, et al. Sequential treatment with ipilimumab and BRAF inhibitors in patients with metastatic melanoma: data from the Italian cohort of ipilimumab expanded access programme (EAP). J Clin Oncol. 2013; 31 (suppl): abstract 9035.
-
(2013)
J Clin Oncol.
, vol.31
, Issue.SUPPL.
-
-
Ascierto, P.A.1
Simeone, E.2
Chiarion-Sileni, V.3
-
13
-
-
84874872137
-
BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma
-
Frederick DT, Piris A, Cogdill AP, et al. BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma. Clin Cancer Res. 2013; 19: 1225-1231.
-
(2013)
Clin Cancer Res.
, vol.19
, pp. 1225-1231
-
-
Frederick, D.T.1
Piris, A.2
Cogdill, A.P.3
-
14
-
-
77954373338
-
Selective BRAFV600E inhibition enhances T-cell recognition of melanoma without affecting lymphocyte function
-
Boni A, Cogdill AP, Dang P, et al. Selective BRAFV600E inhibition enhances T-cell recognition of melanoma without affecting lymphocyte function. Cancer Res. 2010; 70: 5213-5219.
-
(2010)
Cancer Res.
, vol.70
, pp. 5213-5219
-
-
Boni, A.1
Cogdill, A.P.2
Dang, P.3
-
15
-
-
84880294344
-
Vemurafenib reverses immunosuppression by myeloid derived suppressor cells
-
Schilling B, Sucker A, Griewank K, et al. Vemurafenib reverses immunosuppression by myeloid derived suppressor cells. Int J Cancer. 2013; 133: 1653-1663.
-
(2013)
Int J Cancer.
, vol.133
, pp. 1653-1663
-
-
Schilling, B.1
Sucker, A.2
Griewank, K.3
-
16
-
-
73149092567
-
Guidelines for the evaluation of immune therapy activity in solid tumors: Immune-related response criteria
-
Wolchok JD, Hoos A, O'Day S, et al. Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria. Clin Cancer Res. 2009; 23: 7412-7420.
-
(2009)
Clin Cancer Res.
, vol.23
, pp. 7412-7420
-
-
Wolchok, J.D.1
Hoos, A.2
O'Day, S.3
-
17
-
-
84860446616
-
Ipilimumab in patients with melanoma and brain metastases: An open-label, phase 2 trial
-
Margolin K, Ernstoff MS, Hamid O, et al. Ipilimumab in patients with melanoma and brain metastases: an open-label, phase 2 trial. Lancet Oncol. 2012; 13: 459-465.
-
(2012)
Lancet Oncol.
, vol.13
, pp. 459-465
-
-
Margolin, K.1
Ernstoff, M.S.2
Hamid, O.3
|