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Volumn 121, Issue 5, 2014, Pages 533-542

Potential involvement of GRIN2B encoding the NMDA receptor subunit NR2B in the spectrum of Alzheimer's disease

Author keywords

Alzheimer's dementia; Excitotoxicity; Glutamate; N methyl d aspartate receptors GRIN2B gene; Regulation of synaptogenesis

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; APOLIPOPROTEIN E4; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NR2B NMDA RECEPTOR;

EID: 84901306605     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-013-1125-7     Document Type: Article
Times cited : (40)

References (46)
  • 2
    • 77953285667 scopus 로고    scopus 로고
    • Dissociable influences of NR2B-receptor related neural transmission on functions of distinct associative basal ganglia circuits
    • doi:0.1016/.neuroimage.010.4.22
    • Beste C, Baune BT, Domschke K, Falkenstein M, Konrad C (2010) Dissociable influences of NR2B-receptor related neural transmission on functions of distinct associative basal ganglia circuits. Neuroimage 52(1):309-315. doi:0.1016/.neuroimage.010.4.22
    • (2010) Neuroimage , vol.52 , Issue.1 , pp. 309-315
    • Beste, C.1    Baune, B.T.2    Domschke, K.3    Falkenstein, M.4    Konrad, C.5
  • 3
    • 0037102726 scopus 로고    scopus 로고
    • N-methyl-D-aspartate receptor subunit NR2A and NR2B messenger RNA levels are altered in the hippocampus and entorhinal cortex in Alzheimer's disease
    • doi:0.1016/S0022-510X
    • Bi H, Sze CI (2002) N-methyl-D-aspartate receptor subunit NR2A and NR2B messenger RNA levels are altered in the hippocampus and entorhinal cortex in Alzheimer's disease. J Neurol Sci 200(1-2):11-18. doi:0.1016/S0022-510X
    • (2002) J Neurol Sci , vol.200 , Issue.1-2 , pp. 11-18
    • Bi, H.1    Sze, C.I.2
  • 4
    • 84934444326 scopus 로고    scopus 로고
    • Pharmacogenomics in Alzheimer's disease
    • doi:10.1007/978-1-59745-205-2-10
    • Cacabelos R (2008) Pharmacogenomics in Alzheimer's disease. Methods Mol Biol 448:213-357. doi:10.1007/978-1-59745-205-2-10
    • (2008) Methods Mol Biol , vol.448 , pp. 213-357
    • Cacabelos, R.1
  • 5
    • 30744432134 scopus 로고    scopus 로고
    • Evidence for selection on synonymous mutations affecting stability of mRNA secondary structure in mammals
    • doi:10.1186/gb-2005-6-9-r75
    • Chamary JV, Hurst LD (2005) Evidence for selection on synonymous mutations affecting stability of mRNA secondary structure in mammals. Genome Biol 6(9):R75. doi:10.1186/gb-2005-6-9-r75
    • (2005) Genome Biol , vol.6 , Issue.9
    • Chamary, J.V.1    Hurst, L.D.2
  • 6
    • 67650264293 scopus 로고    scopus 로고
    • The price of silent mutations
    • Chamary JV, Hurst LD (2009) The price of silent mutations. Sci Am 300(6):46-53
    • (2009) Sci Am , vol.300 , Issue.6 , pp. 46-53
    • Chamary, J.V.1    Hurst, L.D.2
  • 7
    • 78650213415 scopus 로고    scopus 로고
    • Association between NMDA receptor subunit 2b gene polymorphism and Alzheimer's disease in Chinese Han population in Shanghai
    • doi:10.1007/s12264-010-0729-2
    • Chen C, Li X, Wang T, Wang HH, Fu Y, Zhang L, Xiao SF (2010) Association between NMDA receptor subunit 2b gene polymorphism and Alzheimer's disease in Chinese Han population in Shanghai. Neurosci Bull 26(5):395-400. doi:10.1007/s12264-010-0729-2
    • (2010) Neurosci Bull , vol.26 , Issue.5 , pp. 395-400
    • Chen, C.1    Li, X.2    Wang, T.3    Wang, H.H.4    Fu, Y.5    Zhang, L.6    Xiao, S.F.7
  • 8
    • 0027263699 scopus 로고
    • Population-based norms for the Mini-Mental State Examination by age and educational level
    • DOI 10.1001/jama.269.18.2386
    • Crum RM, Anthony JC, Bassett SS, Folstein M (1993) Population-based norms for the Mini- Mental State Examination by age and educational level. JAMA 269(18):2386-2391. doi:10.1001/jama.1993.03500180078038 (Pubitemid 23129378)
    • (1993) Journal of the American Medical Association , vol.269 , Issue.18 , pp. 2386-2391
    • Crum, R.M.1    Anthony, J.C.2    Bassett, S.S.3    Folstein, M.F.4
  • 10
    • 16544376850 scopus 로고    scopus 로고
    • Role of distinct NMDA receptor subtypes at central synapses
    • Cull-Candy SG, Leszkiewicz DN (2004) Role of distinct NMDA receptor subtypes at central synapses. Sci STKE 2004(255):re16
    • (2004) Sci STKE , vol.2004 , Issue.255
    • Cull-Candy, S.G.1    Leszkiewicz, D.N.2
  • 11
    • 84865405744 scopus 로고    scopus 로고
    • Alzheimer's disease, β-amyloid, glutamate, NMDA receptors and memantine - Searching for the connections
    • doi:10.1111/j.1476-5381.2012.02057
    • Danysz W, Parsons CG (2012) Alzheimer's disease, β-amyloid, glutamate, NMDA receptors and memantine - searching for the connections. Br J Pharmacol 67(2):324-352. doi:10.1111/j.1476-5381.2012.02057
    • (2012) Br J Pharmacol , vol.67 , Issue.2 , pp. 324-352
    • Danysz, W.1    Parsons, C.G.2
  • 12
    • 84856992257 scopus 로고    scopus 로고
    • Apolipoprotein ε4 modulates phenotype of butyrylcholinesterase in CSF of patients with Alzheimer's disease
    • doi:10.3233/JAD-2011-111088
    • Darreh-Shori T, Siawesh M, Mousavi M, Andreasen N, Nordberg A (2012) Apolipoprotein ε4 modulates phenotype of butyrylcholinesterase in CSF of patients with Alzheimer's disease. J Alzheimers Dis 28(2):443-458. doi:10.3233/JAD-2011-111088
    • (2012) J Alzheimers Dis , vol.28 , Issue.2 , pp. 443-458
    • Darreh-Shori, T.1    Siawesh, M.2    Mousavi, M.3    Andreasen, N.4    Nordberg, A.5
  • 15
    • 0038059078 scopus 로고    scopus 로고
    • The use of denaturing high-performance liquid chromatography (DHPLC) for the analysis of genetic variations: Impact for diagnostics and pharmacogenetics
    • DOI 10.1515/CCLM.2003.068
    • Frueh FW, Noyer-Weidner M (2003) The use of denaturing high-performance liquid chromatography (DHPLC) for the analysis of genetic variations: impact for diagnostic and pharmacogenetics. Clin Chem Lab Med 41(4):452-461. doi:10.15/CCLM.2003.068 (Pubitemid 36592108)
    • (2003) Clinical Chemistry and Laboratory Medicine , vol.41 , Issue.4 , pp. 452-461
    • Frueh, F.W.1    Noyer-Weidner, M.2
  • 17
    • 84855819016 scopus 로고    scopus 로고
    • The genetic architecture of Alzheimer's disease: Beyond APP, PSENs and APOE
    • doi:10.1016/j.neurobiolaging.2010.03.025
    • Guerreiro RJ, Gustafson DR, Hardy J (2012) The genetic architecture of Alzheimer's disease: beyond APP, PSENs and APOE. Neurobiol Aging 33(3):437-456. doi:10.1016/j.neurobiolaging.2010.03.025
    • (2012) Neurobiol Aging , vol.33 , Issue.3 , pp. 437-456
    • Guerreiro, R.J.1    Gustafson, D.R.2    Hardy, J.3
  • 18
    • 3142752973 scopus 로고    scopus 로고
    • Export from the endoplasmic reticulum of assembled N-methyl-D-aspartic acid receptors is controlled by a motif in the C terminus of the NR2 subunit
    • DOI 10.1074/jbc.M402599200
    • Hawkins LM, Prybylowski K, Chang K, Moussan C, Stephenson FA, Wenthold RJ (2004) Export from the endoplasmic reticulum of assembled N-Methyl-D-aspartic Acid receptors is controlled by a motif in the C terminus of the NR2 subunit. J Biol Chem 279(28):28903-28910. doi:10.1074/jbc.M402599200 (Pubitemid 38915758)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.28 , pp. 28903-28910
    • Hawkins, L.M.1    Prybylowski, K.2    Chang, K.3    Moussan, C.4    Stephenson, F.A.5    Wenthold, R.J.6
  • 19
    • 84855523295 scopus 로고    scopus 로고
    • Glutamate receptors in preclinical research on Alzheimer's disease: Update on recent advances
    • doi:10.1016/j.pbb.2011.04.013
    • Hu NW, Ondrejcak T, Rowan MJ (2012) Glutamate receptors in preclinical research on Alzheimer's disease: update on recent advances. Pharmacol Biochem Behav 100(4):855-862. doi:10.1016/j.pbb.2011.04.013
    • (2012) Pharmacol Biochem Behav , vol.100 , Issue.4 , pp. 855-862
    • Hu, N.W.1    Ondrejcak, T.2    Rowan, M.J.3
  • 20
    • 58149469521 scopus 로고    scopus 로고
    • Association between NR2B subunit gene (GRIN2B) promoter polymorphisms and sporadic Alzheimer's disease in the North Chinese population
    • doi:10.1016/j.neulet.2008.10.075
    • Jiang H, Jia J (2009) Association between NR2B subunit gene (GRIN2B) promoter polymorphisms and sporadic Alzheimer's disease in the North Chinese population. Neurosci Lett 450(3):356-360. doi:10.1016/j.neulet.2008.10.075
    • (2009) Neurosci Lett , vol.450 , Issue.3 , pp. 356-360
    • Jiang, H.1    Jia, J.2
  • 22
    • 34249099711 scopus 로고    scopus 로고
    • NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders
    • DOI 10.1038/nrn2153, PII NRN2153
    • Lau CG, Zukin RS (2007) NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders. Nat Rev Neurosci 8(6):413-426. doi:10.1038/nrn2153 (Pubitemid 46789232)
    • (2007) Nature Reviews Neuroscience , vol.8 , Issue.6 , pp. 413-426
    • Lau, C.G.1    Zukin, R.S.2
  • 23
    • 0030991790 scopus 로고    scopus 로고
    • Molecular determinants of agonist discrimination by NMDA receptor subunits: Analysis of the glutamate binding site on the NR2B subunit
    • DOI 10.1016/S0896-6273(00)81249-0
    • Laube B, Hirai H, Sturgess M, Betz H, Kuhse J (1997) Molecular determinants of agonist discrimination by NMDA receptor subunits: analysis of the glutamate binding site on the NR2B subunit. Neuron 18(3):493-503. doi:10.1016/S0896-6273(00)81249-0 (Pubitemid 27138796)
    • (1997) Neuron , vol.18 , Issue.3 , pp. 493-503
    • Laube, B.1    Hirai, H.2    Sturgess, M.3    Betz, H.4    Kuhse, J.5
  • 24
    • 0036468393 scopus 로고    scopus 로고
    • Uncommon polymorphism in the presenilin genes in human familial Alzheimer's disease: Not to be mistaken with a pathogenic mutation
    • DOI 10.1016/S0304-3940(01)02499-5, PII S0304394001024995
    • Lleó A, Castellví M, Blesa R, Oliva R (2002) Uncommon polymorphism in the presenilin genes in familial Alzheimer's disease: not to be mistaken as a pathogenic mutation. Neurosci Lett 318(3):166-168. doi:10.1016/S0304-3940(01)02499-5 (Pubitemid 34136035)
    • (2002) Neuroscience Letters , vol.318 , Issue.3 , pp. 166-168
    • Lleo, A.1    Castellvi, M.2    Blesa, R.3    Oliva, R.4
  • 25
    • 84862561404 scopus 로고    scopus 로고
    • A novel genome-information content-based statistic for genome-wide association analysis designed for next-generation sequencing data
    • doi:10.1089/cmb.2012.0035
    • Luo L, Zhu Y, Xiong M (2012) A novel genome-information content-based statistic for genome-wide association analysis designed for next-generation sequencing data. J Comput Biol 19(6):731-744. doi:10.1089/cmb.2012.0035
    • (2012) J Comput Biol , vol.19 , Issue.6 , pp. 731-744
    • Luo, L.1    Zhu, Y.2    Xiong, M.3
  • 26
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease
    • McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34(7):939-944 (Pubitemid 14076461)
    • (1984) Neurology , vol.34 , Issue.7 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3
  • 27
    • 79551632703 scopus 로고    scopus 로고
    • Mutations in NMDA receptors influence neurodevelopmental disorders causing epilepsy and intellectual disability
    • doi:10.1111/j.1399-0004.2010.01610.x
    • Metzler M (2011) Mutations in NMDA receptors influence neurodevelopmental disorders causing epilepsy and intellectual disability. Clin Genet 79(3):219-220. doi:10.1111/j.1399-0004.2010.01610.x
    • (2011) Clin Genet , vol.79 , Issue.3 , pp. 219-220
    • Metzler, M.1
  • 28
    • 70350324907 scopus 로고    scopus 로고
    • Allosteric modulators of NR2B- containing NMDA receptors: Molecular mechanisms and therapeutic potential
    • doi:10.1111/j.1476-5381.2009.00304.x
    • Mony L, Kew JN, Gunthorpe MJ, Paoletti P (2009) Allosteric modulators of NR2B- containing NMDA receptors: molecular mechanisms and therapeutic potential. Br J Pharmacol 157(8):1301-1317. doi:10.1111/j.1476-5381.2009.00304.x
    • (2009) Br J Pharmacol , vol.157 , Issue.8 , pp. 1301-1317
    • Mony, L.1    Kew, J.N.2    Gunthorpe, M.J.3    Paoletti, P.4
  • 30
    • 0030782939 scopus 로고    scopus 로고
    • Excitotoxic neurodegeneration in Alzheimer disease: New hypothesis and new therapeutic strategies
    • Olney JW, Wozniak DF, Farber NB (1997) Excitotoxic neurodegeneration in Alzheimer disease: new hypothesis and new therapeutic strategies. Arch Neurol 4(10):1234-1240. doi:10.1001/archneur.1997.00550220042012 (Pubitemid 27452238)
    • (1997) Archives of Neurology , vol.54 , Issue.10 , pp. 1234-1240
    • Olney, J.W.1    Wozniak, D.F.2    Farber, N.B.3
  • 31
    • 79954630544 scopus 로고    scopus 로고
    • Molecular basis of NMDA receptor functional diversity
    • doi:10.1111/j.1460-9568.2011.07628
    • Paoletti P (2011) Molecular basis of NMDA receptor functional diversity. Eur J Neurosci 33(8):1351-1365. doi:10.1111/j.1460-9568.2011.07628
    • (2011) Eur J Neurosci , vol.33 , Issue.8 , pp. 1351-1365
    • Paoletti, P.1
  • 32
    • 84861075505 scopus 로고    scopus 로고
    • Distribution of extrasynaptic NMDA receptors on neurons
    • doi:10.1100/2012/267120
    • Petralia RS (2012) Distribution of extrasynaptic NMDA receptors on neurons. Sci World J 2012:267120. doi:10.1100/2012/267120
    • (2012) Sci World J , vol.2012 , pp. 267120
    • Petralia, R.S.1
  • 33
    • 42149142899 scopus 로고    scopus 로고
    • Memantine treatment in patients with mild to moderate Alzheimer's disease already receiving a cholinesterase inhibitor: A randomized, double-blind, placebo-controlled trial
    • DOI 10.2174/156720508783884576
    • Porsteinsson AP, Grossberg GT, Mintzer J, Olin JT, Memantine MEM-MD-12 Study Group (2008) Memantine treatment in patients) with mild to disease moderate Alzheimer's already receiving a cholinesterase inhibitor: a randomized, double-blind, placebo-controlled trial. Curr Alzheimer Res 5(1):83-89. doi:10.2174/5672058783884576 (Pubitemid 351536358)
    • (2008) Current Alzheimer Research , vol.5 , Issue.1 , pp. 83-89
    • Porsteinsson, A.P.1    Grossberg, G.T.2    Mintzer, J.3    Olin, J.T.4
  • 35
    • 84922685825 scopus 로고    scopus 로고
    • Association of apolipoprotein E epsilon 4 allele with sporadic late onset Alzheimer's disease: A meta-analysis
    • Riyadh
    • Sadigh-Eteghad S, Talebi M, Farhoudi M (2012) Association of apolipoprotein E epsilon 4 allele with sporadic late onset Alzheimer's disease: a meta-analysis. Neurosciences (Riyadh) 17(4):321-326
    • (2012) Neurosciences , vol.17 , Issue.4 , pp. 321-326
    • Sadigh-Eteghad, S.1    Talebi, M.2    Farhoudi, M.3
  • 43
    • 0034656234 scopus 로고    scopus 로고
    • NMDA receptor subunit NR1, NR2A, and NR2B proteins and their phosphorylation status are altered selectively in Alzheimer's disease
    • doi:10.1016/S0022-510X(00)00285-9
    • Sze CI, Bi H, Kleinschmidt-DeMasters BK, Filley CM, Martin LJ (2001) NMDA receptor subunit NR1, NR2A, and NR2B proteins and their phosphorylation status are altered selectively in Alzheimer's disease. J Neurol Sci 175(2):81-90. doi:10.1016/S0022-510X(00)00285-9
    • (2001) J Neurol Sci , vol.175 , Issue.2 , pp. 81-90
    • Sze, C.I.1    Bi, H.2    Kleinschmidt-DeMasters, B.K.3    Filley, C.M.4    Martin, L.J.5
  • 45
    • 34250797930 scopus 로고    scopus 로고
    • Memantine in moderate to severe alzheimer's disease: A meta-analysis of randomised clinical trials
    • DOI 10.1159/000102568
    • Winblad B, Jones RW, Wirth Y, Stöffler A, Möbius HJ (2007) Memantine in moderate to severe Alzheimer's disease: a meta-analysis of randomised clinical trials. Dement Geriatr Cogn Disord 24(1):20-27. doi:10.1159/000102568 (Pubitemid 46985287)
    • (2007) Dementia and Geriatric Cognitive Disorders , vol.24 , Issue.1 , pp. 20-27
    • Winblad, B.1    Jones, R.W.2    Wirth, Y.3    Stoffler, A.4    Mobius, H.J.5
  • 46
    • 34247866327 scopus 로고    scopus 로고
    • A three amino acid tail following the TM4 region of the N-methyl-D-aspartate receptor (NR) 2 subunits is sufficient to overcome endoplasmic reticulum retention of NR1-1a subunit
    • DOI 10.1074/jbc.M700050200
    • Yang W, Zheng C, Song Q, Yang X, Qiu S, Liu C, Chen Z, Duan S, Luo J (2007) A three amino acid tail following the TM4 region of the N-methyl-D-aspartate receptor (NR)2 subunits is sufficient to overcome endoplasmic reticulum retention of NR1-1a subunit. J Biol Chem 282(12):9269-9278. doi:10.1074/jbc.M700050200 (Pubitemid 47093485)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.12 , pp. 9269-9278
    • Yang, W.1    Zheng, C.2    Song, Q.3    Yang, X.4    Qiu, S.5    Liu, C.6    Chen, Z.7    Duan, S.8    Luo, J.9


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