Heparin-binding mechanism of the IGF2/IGF-binding protein 2 complex

Journal of Molecular Endocrinology

Volumn 52, Issue 3, 2014, Pages 345-355

  Lund, Jacob ^a   Søndergaard, Mads T ^a   Conover, Cheryl A ^b   Overgaard, Michael T ^a  

^a AALBORG UNIVERSITY   (Denmark)

^b MAYO CLINIC   (United States)

Author keywords

Glycosaminoglycans; Heparin affinity; IGF2 IGFBP2 complex; Ternary binding model

Indexed keywords

GLYCOSAMINOGLYCAN POLYSULFATE; HEPARIN; HEPARIN BINDING PROTEIN; MULTIPROTEIN COMPLEX; SOMATOMEDIN B; SOMATOMEDIN BINDING PROTEIN 2; HYBRID PROTEIN; IGF2 PROTEIN, HUMAN; PROTEIN BINDING;

AFFINITY CHROMATOGRAPHY; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONTROLLED STUDY; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; QUANTITATIVE ANALYSIS; AMINO ACID SEQUENCE; BINDING SITE; BONE DEVELOPMENT; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; OSTEOBLAST; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; BINDING SITES; CHROMATOGRAPHY, AFFINITY; HEPARIN; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 2; INSULIN-LIKE GROWTH FACTOR II; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OSTEOBLASTS; OSTEOGENESIS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT;

EID: 84901302830     PISSN: 09525041     EISSN: 14796813     Source Type: Journal    
DOI: 10.1530/JME-13-0184     Document Type: Article

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