Involvement of extracellular signal-regulated kinase (ERK1/2)-p53-p21 axis in mediating neural stem/progenitor cell cycle arrest in co-morbid HIV-drug abuse exposure

Journal of Neuroimmune Pharmacology

Volumn 9, Issue 3, 2014, Pages 340-353

  Malik, Shaily ^a   Saha, Rinki ^a,b   Seth, Pankaj ^a  

^a NATIONAL BRAIN RESEARCH CENTRE   (India)

^b UNIVERSITY OF HAIFA   (Israel)

Author keywords

Cell cycle; HIV Tat; Neural progenitor cells; Opioid; p21; Proliferation

Indexed keywords

CYCLIN D1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MORPHINE; PROTEIN KINASE B; PROTEIN P21; PROTEIN P53; TRANSACTIVATOR PROTEIN; APOPTOSIS REGULATORY PROTEIN; HIV-TAT-SURVIVIN (T34A) PROTEIN; HYBRID PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN;

ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; COMORBIDITY; CONTROLLED STUDY; DRUG ABUSE; EXPOSURE; FETUS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; IN VITRO STUDY; INFECTION SENSITIVITY; MULTIPOTENT STEM CELL; NERVE DEGENERATION; NEURAL STEM CELL; NEUROLOGICAL COMPLICATION; NONHUMAN; PRIORITY JOURNAL; BIOSYNTHESIS; CELL CULTURE; CELL CYCLE CHECKPOINT; DRUG EFFECTS; FETAL STEM CELL; HIV INFECTIONS; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; SUBSTANCE-RELATED DISORDERS; TOXICITY;

APOPTOSIS REGULATORY PROTEINS; CELL CYCLE CHECKPOINTS; CELLS, CULTURED; COMORBIDITY; FETAL STEM CELLS; HIV INFECTIONS; HUMANS; MAP KINASE SIGNALING SYSTEM; MORPHINE; NEURAL STEM CELLS; RECOMBINANT FUSION PROTEINS; RHO GTP-BINDING PROTEINS; SUBSTANCE-RELATED DISORDERS; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84901259174     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-014-9523-7     Document Type: Article

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