Serum levels of procalcitonin as a biomarker for differentiating between sepsis and systemic inflammatory response syndrome in the neurological intensive care unit

Journal of Clinical Neuroscience

Volumn 21, Issue 7, 2014, Pages 1153-1158

  Tian, Ge ^a   Pan, Su Yue ^a   Ma, Gang ^c   Liao, Wei ^c   Su, Quan Guan ^c   Gu, Bao Chun ^c   Qin, Kun ^b  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b GUANGDONG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^c SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

Author keywords

C reactive protein; Glasgow Coma Scale; Neurological intensive care unit; Procalcitonin; Sepsis; Systemic inflammatory response syndrome

Indexed keywords

C REACTIVE PROTEIN; PROCALCITONIN; CALCITONIN; PROTEIN PRECURSOR;

ADULT; ARTICLE; BACTERIAL MENINGITIS; COMPARATIVE STUDY; CONTROLLED STUDY; CRITICALLY ILL PATIENT; DIFFERENTIAL DIAGNOSIS; DISEASE MARKER; DISEASE SEVERITY; FEMALE; GLASGOW COMA SCALE; HORMONE BLOOD LEVEL; HUMAN; INTENSIVE CARE UNIT; LENGTH OF STAY; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; NEUROLOGIC DISEASE; NEUROLOGICAL INTENSIVE CARE UNIT; PATIENT MONITORING; PREDICTIVE VALUE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RECEIVER OPERATING CHARACTERISTIC; REFERENCE VALUE; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; SEPSIS; SEPTIC SHOCK; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; VIRUS MENINGITIS; AGED; BLOOD; METABOLISM; MIDDLE AGED; NONPARAMETRIC TEST;

ADULT; AGED; C-REACTIVE PROTEIN; CALCITONIN; FEMALE; GLASGOW COMA SCALE; HUMANS; INTENSIVE CARE UNITS; MALE; MIDDLE AGED; PROTEIN PRECURSORS; RETROSPECTIVE STUDIES; ROC CURVE; SEPSIS; STATISTICS, NONPARAMETRIC; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

EID: 84901231898     PISSN: 09675868     EISSN: 15322653     Source Type: Journal    
DOI: 10.1016/j.jocn.2013.09.021     Document Type: Article

References (28)

1. E.P. Rivers, L. McIntyre, and D.C. Morro et al. Early and innovative interventions for severe sepsis and septic shock: taking advantage of a window of opportunity CMAJ 173 2005 1054 1065
2. R.P. Dellinger, M.M. Levy, and J.M. Carlet et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2008 Crit Care Med 36 2008 296 327
3. L.G. Reimer, M.L. Wilson, and M.P. Weinstein Update on detection of bacteremia and fungemia Clin Microbiol Rev 10 1997 444 465
4. C. Pierrakos, and J.L. Vincent Sepsis biomarkers: a review Crit Care 14 2010 R15
5. F.M. Brunkhorst, K. Wegscheider, and Z.F. Forycki et al. Procalcitonin for early diagnosis and differentiation of SIRS, sepsis, severe sepsis, and septic shock Intensive Care Med 26 2000 S148 S152
6. C. Clec'h, F. Ferriere, and P. Karoubi et al. Diagnostic and prognostic value of procalcitonin in patients with septic shock Crit Care Med 32 2004 1166 1169
7. B.M. Tang, G.D. Eslick, and J.C. Craig et al. Accuracy of procalcitonin for sepsis diagnosis in critically ill patients: systematic review and meta-analysis Lancet Infect Dis 7 2007 210 217
8. B. Uzzan, R. Cohen, and P. Nicolas et al. Procalcitonin as a diagnostic test for sepsis in critically ill adults and after surgery or trauma: a systematic review and meta-analysis Crit Care Med 34 2006 1996 2003
9. Y.L. Chan, C.P. Tseng, and P.K. Tsay et al. Procalcitonin as a marker of bacterial infection in the emergency department: an observational study Crit Care 8 2004 R12 R20
10. B. Muller Endocrine aspects of critical illness Ann Endocrinol (Paris) 68 2007 290 298
11. C. Sponholz, Y. Sakr, and K. Reinhart et al. Diagnostic value and prognostic implications of serum procalcitonin after cardiac surgery: a systematic review of the literature Crit Care 10 2006 R145
12. K.A. Muthiah, K.S. Rachakonda, and M.J. Davis et al. Prospective evaluation of procalcitonin in sepsis in the Illawarra area of Australia: PEPSIA study Crit Care Resusc 9 2007 137 142
13. S. Kushimoto, Y. Shibata, and Y. Koido et al. The clinical usefulness of procalcitonin measurement for assessing the severity of bacterial infection in critically ill patients requiring corticosteroid therapy J Nippon Med Sch 74 2007 236 240
14. K.L. Becker, R. Snider, and E.S. Nylen Procalcitonin assay in systemic inflammation, infection, and sepsis: clinical utility and limitations Crit Care Med 36 2008 941 952
15. R.C. Bone, R.A. Balk, and F.B. Cerra et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. 1992 Chest 136 2009 e28
16. M.M. Levy, M.P. Fink, and J.C. Marshall et al. 2001 SCCM/ESICM/ACCP/ATS/ SIS International Sepsis Definitions Conference Crit Care Med 31 2003 1250 1256
17. R.P. Dellinger, M.M. Levy, and J.M. Carlet et al. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008 Intensive Care Med 34 2008 17 60
18. I.A. Meynaar, W. Droog, and M. Batstra et al. In critically ill patients, serum procalcitonin is more useful in differentiating between sepsis and SIRS than CRP, Il-6, or LBP Crit Care Res Pract 2011 2011 594645
19. J. Casado-Flores, A. Blanco-Quiros, and M. Nieto et al. Prognostic utility of the semi-quantitative procalcitonin test, neutrophil count and C-reactive protein in meningococcal infection in children Eur J Pediatr 165 2006 26 29
20. N.Y. Boo, A.A. Nor Azlina, and J. Rohana Usefulness of a semi-quantitative procalcitonin test kit for early diagnosis of neonatal sepsis Singapore Med J 49 2008 204 208
21. F. Ramsthaler, M. Kettner, and G. Mall et al. The use of rapid diagnostic test of procalcitonin serum levels for the postmortem diagnosis of sepsis Forensic Sci Int 178 2008 139 145
22. F.S. Meng, L. Su, and Y.Q. Tang et al. Serum procalcitonin at the time of admission to the ICU as a predictor of short-term mortality Clin Biochem 42 2009 1025 1031
23. Y.O. Erickson, N.I. Samia, and B. Bedell et al. Elevated procalcitonin and C-reactive protein as potential biomarkers of sepsis in a subpopulation of thrombotic microangiopathy patients J Clin Apher 24 2009 150 154
24. C.C. Lee, S.Y. Chen, and C.L. Tsai et al. Prognostic value of mortality in emergency department sepsis score, procalcitonin, and C-reactive protein in patients with sepsis at the emergency department Shock 29 2008 322 327
25. G.P. Castelli, C. Pognani, and M. Cita et al. Procalcitonin, C-reactive protein, white blood cells and SOFA score in ICU: diagnosis and monitoring of sepsis Minerva Anestesiol 72 2006 69 80
26. U.M. Alkholi, N. Abd Al-Monem, and A.A. Abd El-Azim et al. Serum procalcitonin in viral and bacterial meningitis J Global Infect Dis 3 2011 14 18
27. N.P. O'Grady, P.S. Barie, and J.G. Bartlett et al. Guidelines for evaluation of new fever in critically ill adult patients: 2008 update from the American College of Critical Care Medicine and the Infectious Diseases Society of America Crit Care Med 36 2008 1330 1349
28. R.M. Dorizzi, E. Polati, and P. Sette et al. Procalcitonin in the diagnosis of inflammation in intensive care units Clin Biochem 39 2006 1138 1143