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Volumn 29, Issue 2, 2014, Pages 215-218

Association of the CYP2B6 c.516G>T polymorphism with high blood propofol concentrations in women from Northern Greece

Author keywords

Blood propofol; CYP2B6; GC MS; Gene polymorphism

Indexed keywords

CYTOCHROME P450 2B6; PROPOFOL; CYP2B6 PROTEIN, HUMAN; INTRAVENOUS ANESTHETIC AGENT;

EID: 84901229099     PISSN: 13474367     EISSN: 18800920     Source Type: Journal    
DOI: 10.2133/dmpk.DMPK-13-NT-092     Document Type: Article
Times cited : (29)

References (15)
  • 2
    • 0031955972 scopus 로고    scopus 로고
    • The influence of method of administration and covariates on the pharmacokinetics of propofol in adult volunteers
    • Schnider, T. W., Minto, C. F., Gambus, P. L., Andresen, C., Goodale, D. B., Shafer, S. L. and Youngs, E. J.: The influence of method of administration and covariates on the pharmacokinetics of propofol in adult volunteers. Anesthesiology, 88: 1170-1182 (1998).
    • (1998) Anesthesiology , vol.88 , pp. 1170-1182
    • Schnider, T.W.1    Minto, C.F.2    Gambus, P.L.3    Andresen, C.4    Goodale, D.B.5    Shafer, S.L.6    Youngs, E.J.7
  • 4
    • 4143072423 scopus 로고    scopus 로고
    • Identification of common polymorphisms in the promoter of the UGT1A9 gene: Evidence that UGT1A9 protein and activity levels are strongly genetically controlled in the liver
    • Girard, H., Court, M. H., Bernard, O., Fortier, L. C., Villeneuve, L., Hao, Q., Greenblatt, D. J., von Moltke, L. L., Perussed, L., et al.: Identification of common polymorphisms in the promoter of the UGT1A9 gene: evidence that UGT1A9 protein and activity levels are strongly genetically controlled in the liver. Pharmacogenetics, 14: 501-515 (2004).
    • (2004) Pharmacogenetics , vol.14 , pp. 501-515
    • Girard, H.1    Court, M.H.2    Bernard, O.3    Fortier, L.C.4    Villeneuve, L.5    Hao, Q.6    Greenblatt, D.J.7    Von Moltke, L.L.8    Perussed, L.9
  • 5
    • 0035165506 scopus 로고    scopus 로고
    • Cytochrome P-450 2B6 is responsible for interindividual variability of propofol hydroxylation by human liver microsomes
    • Court, M. H., Duan, S. X., Hesse, L. M., Venkatakrishnan, K. and Greenblatt, D. J.: Cytochrome P-450 2B6 is responsible for interindividual variability of propofol hydroxylation by human liver microsomes. Anesthesiology, 94: 110-119 (2001).
    • (2001) Anesthesiology , vol.94 , pp. 110-119
    • Court, M.H.1    Duan, S.X.2    Hesse, L.M.3    Venkatakrishnan, K.4    Greenblatt, D.J.5
  • 7
    • 84876078320 scopus 로고    scopus 로고
    • Pharmacogenetics of cytochrome P450 2B6 (CYP2B6): Advances on polymorphisms, mechanisms, and clinical relevance
    • Zanger, U. M. and Klein, K.: Pharmacogenetics of cytochrome P450 2B6 (CYP2B6): advances on polymorphisms, mechanisms, and clinical relevance. Front. Genet., 4: 24 (2013).
    • (2013) Front. Genet. , vol.4 , pp. 24
    • Zanger, U.M.1    Klein, K.2
  • 8
    • 80055078449 scopus 로고    scopus 로고
    • Individual differences in pharmacokinetics and pharmacodynamics of anesthetic agent propofol with regard to CYP2B6 and UGT1A9 genotype and patient age
    • Kansaku, F., Kumai, T., Sasaki, K., Yokozuka, M., Shimizu, M., Tateda, T., Murayama, N., Kobayashi, S. and Yamazaki, H.: Individual differences in pharmacokinetics and pharmacodynamics of anesthetic agent propofol with regard to CYP2B6 and UGT1A9 genotype and patient age. Drug Metab. Pharmacokinet., 26: 532-537 (2011).
    • (2011) Drug Metab. Pharmacokinet. , vol.26 , pp. 532-537
    • Kansaku, F.1    Kumai, T.2    Sasaki, K.3    Yokozuka, M.4    Shimizu, M.5    Tateda, T.6    Murayama, N.7    Kobayashi, S.8    Yamazaki, H.9
  • 12
    • 41149132905 scopus 로고    scopus 로고
    • Aberrant splicing caused by single nucleotide polymorphism c.516G>T [Q172H], a marker of CYP2B6*6, is responsible for decreased expression and activity of CYP2B6 in the liver
    • Hofmann, M. H., Blievernicht, J. K., Klein, K., Saussele, T., Schaeffeler, E., Schwab, M. and Zanger, U. M.: Aberrant splicing caused by single nucleotide polymorphism c.516G>T [Q172H], a marker of CYP2B6*6, is responsible for decreased expression and activity of CYP2B6 in the liver. J. Pharmacol. Exp. Ther., 325: 284-292 (2008).
    • (2008) J. Pharmacol. Exp. Ther. , vol.325 , pp. 284-292
    • Hofmann, M.H.1    Blievernicht, J.K.2    Klein, K.3    Saussele, T.4    Schaeffeler, E.5    Schwab, M.6    Zanger, U.M.7
  • 15
    • 47649127415 scopus 로고    scopus 로고
    • Effect of D256N and Y483D on propofol glucuronidation by human uridine 5′-diphosphate glucuronosyltransferase (UGT1A9)
    • Takahashi, H., Maruo, Y., Mori, A., Iwai, M., Sato, H. and Takeuchi, Y.: Effect of D256N and Y483D on propofol glucuronidation by human uridine 5′-diphosphate glucuronosyltransferase (UGT1A9). Basic Clin. Pharmacol. Toxicol., 103: 131-136 (2008).
    • (2008) Basic Clin. Pharmacol. Toxicol. , vol.103 , pp. 131-136
    • Takahashi, H.1    Maruo, Y.2    Mori, A.3    Iwai, M.4    Sato, H.5    Takeuchi, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.