ADD ON THERAPY;
ANTIDIABETIC ACTIVITY;
DIABETIC PATIENT;
DRUG EFFICACY;
DRUG SAFETY;
DRUG SELECTIVITY;
HUMAN;
HYPOGLYCEMIA;
JAPANESE (PEOPLE);
MONOTHERAPY;
MULTICENTER STUDY (TOPIC);
NON INSULIN DEPENDENT DIABETES MELLITUS;
OPEN STUDY;
OUTCOME ASSESSMENT;
RANDOMIZED CONTROLLED TRIAL (TOPIC);
REVIEW;
ANALYSIS;
ANTAGONISTS AND INHIBITORS;
BLOOD;
DIABETES MELLITUS, TYPE 2;
DRUG COMBINATION;
GLUCOSE BLOOD LEVEL;
BENZHYDRYL COMPOUNDS;
BLOOD GLUCOSE;
DIABETES MELLITUS, TYPE 2;
DRUG THERAPY, COMBINATION;
GLUCOSIDES;
HUMANS;
HYPOGLYCEMIC AGENTS;
INSULIN;
METFORMIN;
SODIUM-GLUCOSE TRANSPORTER 2;
Management of hyperglycaemia in type 2 diabetes: A patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
Inzucchi SE, Bergenstal RM, Buse JB, et al. Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetologia 2012;55:1577-96
Invokana. Available from: http://www. invokanahcp.com/prescribing- information.pdf [Last accessed 5 April 2014]
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84901041092
Summary of product characteristics, [Last accessed 5 April 2014]
Summary of product characteristics. Available from: http://ec.europa.eu/ health/documents/community-register/2012/20121112124487/anx-124487-en. pdf [Last accessed 5 April 2014]
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Effects of dapagliflozin on body weight, total fat mass, and regional adipose tissue distribution in patients with type 2 diabetes mellitus with inadequate glycemic control on metformin
Bolinder J, Ljunggren O, Kullberg J, et al. Effects of dapagliflozin on body weight, total fat mass, and regional adipose tissue distribution in patients with type 2 diabetes mellitus with inadequate glycemic control on metformin. J Clin Endocrinol Metab 2012;97:1020-31
Dapagliflozin monotherapy in type 2 diabetic patients with inadequate glycemic control by diet and exercise: A randomized, double-blind, placebo-controlled, phase III trial
Ferrannini E. Dapagliflozin monotherapy in type 2 diabetic patients with inadequate glycemic control by diet and exercise: a randomized, double-blind, placebo-controlled, phase III trial. Diabetes Care 2010;33:2217-24
Dapagliflozin, a novel, selective SGLT2 inhibitor, improved glycemic control over 2 weeks in patients with type 2 diabetes mellitus
Komoroski B, Vachharajani N, Feng Y, et al. Dapagliflozin, a novel, selective SGLT2 inhibitor, improved glycemic control over 2 weeks in patients with type 2 diabetes mellitus. Clin Pharmacol Ther 2009;85:513-19
Sodium-glucose cotransporter 2 inhibitors for type 2 diabetes: A systematic review and meta-analysis
Vasilakou D, Karagiannis T, Athanasiadou E, et al. Sodium-glucose cotransporter 2 inhibitors for type 2 diabetes: a systematic review and meta-analysis. Ann Intern Med 2013;159:262-74
FDA approves new diabetes drug, canagliflozin, despite CV concerns, [Accessed 24 January 2014]
FDA approves new diabetes drug, canagliflozin, despite CV concerns. Available from: http://www.medscape.com/viewarticle/791562 [Accessed 24 January 2014]
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Canagliflozin-something new for type 2 diabetes but is it safe and efficacious?
Doggrell SA, McIntyre K. Canagliflozin-something new for type 2 diabetes, but is it safe and efficacious? Expert Opin Pharmacother 2014;15:437-41
Tofogliflozin, a potent and highly specific sodium/glucose cotransporter 2 inhibitor, improves glycemic control in diabetic rats and mice
Suzuki M, Honda K, Fukazawa M, et al. Tofogliflozin, a potent and highly specific sodium/glucose cotransporter 2 inhibitor, improves glycemic control in diabetic rats and mice. J Pharmacol Exp Ther 2012;341:692-701
Long-term safety and efficacy of tofogliflozin, a selective inhibitor of sodium-glucose cotransporter 2, as monotherapy or in combination with other oral antidiabetic agents in Japanese patients with type 2 diabetes mellitus: Multicenter, open-label, randomized controlled trials
Tanizawa Y, kaku K, Araki E, et al. Long-term safety and efficacy of tofogliflozin, a selective inhibitor of sodium-glucose cotransporter 2, as monotherapy or in combination with other oral antidiabetic agents in Japanese patients with type 2 diabetes mellitus: multicenter, open-label, randomized controlled trials. Expert Opin Pharmacother 2014;15(6):749-66
The renal hemodynamic effect of SGLT2 inhibition in patients with type 1 diabetes
Cherney DZ, Perkins BA, Soleymanlou N, et al. The renal hemodynamic effect of SGLT2 inhibition in patients with type 1 diabetes. Circulation 2014;129:587-97