Genome-wide association study identifies ALLC polymorphisms correlated with FEV1 change by corticosteroid

Clinica Chimica Acta

Volumn 436, Issue , 2014, Pages 20-26

  Park, Tae Joon ^a   Park, Jong Sook ^b   Cheong, Hyun Sub ^c   Park, Byung Lae ^c   Kim, Lyoung Hyo ^c   Heo, Jeong Seok ^b   Kim, Yang Ki ^d   Kim, Ki Up ^d   Uh, Soo Taek ^d   Lee, Ho Sung ^d   Na, Joo Ock ^d   Seo, Ki Hyun ^d   Choi, Jae Sung ^d   Kim, Yong Hoon ^d   Kim, Myung Sin ^d   Park, Choon Sik ^b   Shin, Hyoung Doo ^a,c  

^a Sogang University   (South Korea)

^b Soonchunhyang University Bucheon Hospital   (South Korea)

^c SNP Genetics Inc   (South Korea)

^d Soonchunhyang University   (South Korea)

Author keywords

ALLC; FEV1; Genome wide association study; Haplotype; Inhaled corticosteroid; Single nucleotide polymorphism

Indexed keywords

ALLANTOICASE; FLUTICASONE PROPIONATE; ADRENAL CORTEX HORMONES; UREOHYDROLASES;

ADOLESCENT; AGED; ALLC GENE; ARTICLE; ASTHMA; CHROMOSOME 2Q; COHORT ANALYSIS; CONTROLLED CLINICAL TRIAL (TOPIC); CORRELATIONAL STUDY; CORTICOSTEROID THERAPY; DNA POLYMORPHISM; DRUG RESPONSE; ETHNIC GROUP; FEMALE; FORCED EXPIRATORY VOLUME; GENE LOCUS; GENE MAPPING; GENETIC ASSOCIATION; GENETIC IDENTIFICATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; KOREAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; ADULT; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECTS; ENZYMOLOGY; GENETICS; GENOME-WIDE ASSOCIATION STUDY; HAPLOTYPES; HUMANS; MIDDLE AGED; PHYSIOPATHOLOGY; POLYMORPHISM, SINGLE NUCLEOTIDE; YOUNG ADULT;

ADOLESCENT; ADRENAL CORTEX HORMONES; ADULT; AGED; ASTHMA; FEMALE; FORCED EXPIRATORY VOLUME; GENOME-WIDE ASSOCIATION STUDY; HAPLOTYPES; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; UREOHYDROLASES; YOUNG ADULT;

EID: 84901063933     PISSN: 00098981     EISSN: 18733492     Source Type: Journal    
DOI: 10.1016/j.cca.2014.04.023     Document Type: Article

References (37)

1. Jang A.S., Lee J.H., Park S.W., et al. Factors influencing the responsiveness to inhaled glucocorticoids of patients with moderate-to-severe asthma. Chest 2005, 128:1140-1145.
2. O'Connell E.J. Efficacy of budesonide in moderate to severe asthma. Clin Ther 2002, 24:887-905. [discussion 837].
3. Barnes P.J., Pedersen S., Busse W.W. Efficacy and safety of inhaled corticosteroids. New developments. Am J Respir Crit Care Med 1998, 157:S1-S53.
4. Juniper E.F., Kline P.A., Vanzieleghem M.A., et al. Effect of long-term treatment with an inhaled corticosteroid (budesonide) on airway hyperresponsiveness and clinical asthma in nonsteroid-dependent asthmatics. Am Rev Respir Dis 1990, 142:832-836.
5. Gyllfors P., Dahlen S.E., Kumlin M., Larsson K., Dahlen B. Bronchial responsiveness to leukotriene D4 is resistant to inhaled fluticasone propionate. J Allergy Clin Immunol 2006, 118:78-83.
6. Kanniess F., Richter K., Bohme S., Jorres R.A., Magnussen H. Effect of inhaled ciclesonide on airway responsiveness to inhaled AMP, the composition of induced sputum and exhaled nitric oxide in patients with mild asthma. Pulm Pharmacol Ther 2001, 14:141-147.
7. Suissa S., Ernst P. Inhaled corticosteroids: impact on asthma morbidity and mortality. J Allergy Clin Immunol 2001, 107:937-944.
8. Drazen J.M., Silverman E.K., Lee T.H. Heterogeneity of therapeutic responses in asthma. Br Med Bull 2000, 56:1054-1070.
9. Szefler S.J., Martin R.J., King T.S., et al. Significant variability in response to inhaled corticosteroids for persistent asthma. J Allergy Clin Immunol 2002, 109:410-418.
10. Malmstrom K., Rodriguez-Gomez G., Guerra J., et al. Oral montelukast, inhaled beclomethasone, and placebo for chronic asthma. A randomized, controlled trial. Montelukast/Beclomethasone Study Group. Ann Intern Med 1999, 130:487-495.
11. Tamesis G.P., Krawiec M.E. Heterogeneity in response to asthma medications. Curr Opin Allergy Clin Immunol 2007, 7:185-189.
12. Fenech A., Hall I.P. Pharmacogenetics of asthma. Br J Clin Pharmacol 2002, 53:3-15.
13. Kim S.H., Ye Y.M., Lee H.Y., Sin H.J., Park H.S. Combined pharmacogenetic effect of ADCY9 and ADRB2 gene polymorphisms on the bronchodilator response to inhaled combination therapy. J Clin Pharm Ther 2011, 36:399-405.
14. Ye Y.M., Lee H.Y., Kim S.H., et al. Pharmacogenetic study of the effects of NK2R G231E G>A and TBX21 H33Q C>G polymorphisms on asthma control with inhaled corticosteroid treatment. J Clin Pharm Ther 2009, 34:693-701.
15. Ni Z., Tang J., Cai Z., et al. A new pathway of glucocorticoid action for asthma treatment through the regulation of PTEN expression. Respir Res 2011, 12:47.
16. Kim W.J., Sheen S.S., Kim T.H., et al. Association between CRHR1 polymorphism and improved lung function in response to inhaled corticosteroid in patients with COPD. Respirology 2009, 14:260-263.
17. Berce V., Potocnik U. Functional polymorphism in CTLA4 gene influences the response to therapy with inhaled corticosteroids in Slovenian children with atopic asthma. Biomarkers 2010, 15:158-166.
18. Tantisira K.G., Lasky-Su J., Harada M., et al. Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma. N Engl J Med 2011, 365:1173-1183.
19. GINA National Asthma Education and Prevention Program. Expert panel report: guidelines for the diagnosis and management of asthma update on selected topics-2002. J Allergy Clin Immunol 2002, 110:S141-S219.
20. Kim T.H., Chang H.S., Park S.M., et al. Association of angiotensin I-converting enzyme gene polymorphisms with aspirin intolerance in asthmatics. Clin Exp Allergy 2008, 38:1727-1737.
21. Kim T.H., An S.H., Cha J.Y., et al. Association of 5-hydroxytryptamine (serotonin) receptor 4 (5-HTR4) gene polymorphisms with asthma. Respirology 2011, 16:630-638.
22. Matsunaga K., Akamatsu K., Miyatake A., Ichinose M. Natural history and risk factors of obstructive changes over a 10-year period in severe asthma. Respir Med 2013, 10711:355-360.
23. Tomita K., Sano H., Iwanaga T., et al. Association between episodes of upper respiratory infection and exacerbations in adult patients with asthma. J Asthma 2012, 49:253-259.
24. To T., Daly C., Feldman R., McLimont S. Results from a community-based program evaluating the effect of changing smoking status on asthma symptom control. BMC Public Health 2012, 12:293.
25. Barrett J.C., Fry B., Maller J., Daly M.J. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005, 21:263-265.
26. Stephens M., Smith N.J., Donnelly P. A new statistical method for haplotype reconstruction from population data. Am J Hum Genet 2001, 68:978-989.
27. Hakonarson H., Bjornsdottir U.S., Halapi E., et al. Profiling of genes expressed in peripheral blood mononuclear cells predicts glucocorticoid sensitivity in asthma patients. Proc Natl Acad Sci U S A 2005, 102:14789-14794.
28. Vigetti D., Monetti C., Acquati F., Taramelli R., Bernardini G. Human allantoicase gene: cDNA cloning, genomic organization and chromosome localization. Gene 2000, 256:253-260.
29. Vigetti D., Monetti C., Prati M., Gornati R., Bernardini G. Genomic organization and chromosome localization of the murine and human allantoicase gene. Gene 2002, 289:13-17.
30. Repapi E., Sayers I., Wain L.V., et al. Genome-wide association study identifies five loci associated with lung function. Nat Genet 2010, 42:36-44.
31. Postma D.S., Meyers D.A., Jongepier H., et al. Genomewide screen for pulmonary function in 200 families ascertained for asthma. Am J Respir Crit Care Med 2005, 172:446-452.
32. Howard T.D., Postma D.S., Hawkins G.A., et al. Fine mapping of an IgE-controlling gene on chromosome 2q: analysis of CTLA4 and CD28. J Allergy Clin Immunol 2002, 110:743-751.
33. Mao X., Zhu X., Hurren R., Ezzat S., Schimmer A.D. Dexamethasone increases ubiquitin transcription through an SP-1 dependent mechanism in multiple myeloma cells. Leuk Res 2008, 32:1480-1482.
34. Ou X.M., Chen K., Shih J.C. Glucocorticoid and androgen activation of monoamine oxidase A is regulated differently by R1 and Sp1. J Biol Chem 2006, 281:21512-21525.
35. Brinster R.L., Allen J.M., Behringer R.R., Gelinas R.E., Palmiter R.D. Introns increase transcriptional efficiency in transgenic mice. Proc Natl Acad Sci U S A 1988, 85:836-840.
36. Pagani F., Baralle F.E. Genomic variants in exons and introns: identifying the splicing spoilers. Nat Rev Genet 2004, 5:389-396.
37. Oakley R.H., Cidlowski J.A. Cellular processing of the glucocorticoid receptor gene and protein: new mechanisms for generating tissue-specific actions of glucocorticoids. J Biol Chem 2011, 286:3177-3184.