Volumetric brain morphometry changes in patients with obstructive sleep apnea syndrome: Effects of CPAP treatment and literature review

Frontiers in Neurology

Volumn 5 APR, Issue , 2014, Pages

  Huynh, Nelly T ^a,b   Prilipko, Olga ^a   Kushida, Clete A ^a   Guilleminault, Christian ^a  

^a STANFORD UNIVERSITY   (United States)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Continuous positive airway pressure; Functional magnetic resonance imaging; Gray matter volume; Nocturnal hypoxemia; Obstructive sleep apnea syndrome; Volumetric brain morphology; White matter volume

Indexed keywords

ADULT; ARTICLE; BRAIN SIZE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUSIFORM GYRUS; GRAY MATTER; GYRUS RECTUS; HUMAN; INFERIOR PARIETAL LOBULE; INFERIOR TEMPORAL GYRUS; LEFT HEMISPHERE; LINGUAL GYRUS; MALE; MATHEMATICAL VARIABLE; MIDDLE FRONTAL GYRUS; MIDDLE OCCIPITAL GYRUS; MIDDLE TEMPORAL GYRUS; NOCTURNAL HYPOXEMIA DURATION; OCCIPITAL LINGUAL GYRUS; POSITIVE END EXPIRATORY PRESSURE; PRECUNEUS; RIGHT HEMISPHERE; SLEEP DISORDERED BREATHING; SLEEP FRAGMENTATION INDEX; SUPERIOR TEMPORAL GYRUS; UNCUS; VOXEL BASED MORPHOMETRY; WHITE MATTER;

EID: 84901050707     PISSN: None     EISSN: 16642295     Source Type: Journal    
DOI: 10.3389/fneur.2014.00058     Document Type: Article

References (27)

1. Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med (1993) 328:1230-5. doi: 10.1056/NEJM199304293281704.
2. Ancoli-Israel S, Alessi C. Sleep and aging. Am J Geriatr Psychiatry (2005) 13:341-3. doi:10.1176/appi.ajgp.13.5.341.
3. Bedard MA, Montplaisir J, Richer F, Rouleau I, Malo J. Obstructive sleep apnea syndrome: pathogenesis of neuropsychological deficits. J Clin Exp Neuropsychol (1991) 13:950-64. doi:10.1080/01688639108405110.
4. Parish JM, Somers VK. Obstructive sleep apnea and cardiovascular disease. Mayo Clin Proc (2004) 79:1036-46. doi:10.4065/79.8.1036.
5. Yaggi H, Mohsenin V. Obstructive sleep apnea and stroke. Lancet Neurol (2004) 3:333-42. doi:10.1016/S1474-4422(04)00766-5.
6. Caples SM, Gami AS, Somers VK. Obstructive sleep apnea. Ann Intern Med (2005) 142:187-97. doi:10.7326/0003-4819-142-3-200502010-00010.
7. Wolk R, Gami AS, Garcia-Touchard A, Somers VK. Sleep and cardiovascular disease. Curr Probl Cardiol (2005) 30:625-62. doi:10.1016/j.cpcardiol.2005.07.002.
8. Coccagna G, Pollini A, Provini F. Cardiovascular disorders and obstructive sleep apnea syndrome. Clin Exp Hypertens (2006) 28:217-24. doi:10.1080/10641960600549090.
9. Kamba M, Inoue Y, Higami S, Suto Y, Ogawa T, Chen W. Cerebral metabolic impairment in patients with obstructive sleep apnea: an independent association of obstructive sleep apnea with white matter change. J Neurol Neurosurg Psychiatry (2001) 71:334-9. doi:10.1136/jnnp.71.3.334.
10. Macey PM, Henderson LA, Macey KE, Alger JR, Frysinger RC, Woo MA, et al. Brain morphology associated with obstructive sleep apnea. Am J Respir Crit Care Med (2002) 166:1382-7. doi:10.1164/rccm.200201-050OC.
11. Morrell MJ, McRobbie DW, Quest RA, Cummin AR, Ghiassi R, Corfield DR. Changes in brain morphology associated with obstructive sleep apnea. Sleep Med (2003) 4:451-4. doi:10.1016/S1389-9457(03)00159-X.
12. O'Donoghue FJ, Briellmann RS, Rochford PD, Abbott DF, Pell GS, Chan CH, et al. Cerebral structural changes in severe obstructive sleep apnea. Am J Respir Crit Care Med (2005) 171:1185-90. doi:10.1164/rccm.200406-738OC.
13. Macey PM, Kumar R, Woo MA, Valladares EM, Yan-Go FL, Harper RM. Brain structural changes in obstructive sleep apnea. Sleep (2008) 31:967-77.
14. Canessa N, Castronovo V, Cappa SF, Aloia MS, Marelli S, Falini A, et al. Obstructive sleep apnea: brain structural changes and neurocognitive function before and after treatment. Am J Respir Crit Care Med (2011) 183:1419-26. doi:10.1164/rccm.201005-0693OC.
15. O'Donoghue FJ, Wellard RM, Rochford PD, Dawson A, Barnes M, Ruehland WR, et al. Magnetic resonance spectroscopy and neurocognitive dysfunction in obstructive sleep apnea before and after CPAP treatment. Sleep (2012) 35:41-8. doi:10.5665/sleep.1582.
16. Joo EY, Tae WS, Lee MJ, Kang JW, Park HS, Lee JY, et al. Reduced brain gray matter concentration in patients with obstructive sleep apnea syndrome. Sleep (2010) 33:235-41.
17. Torelli F, Moscufo N, Garreffa G, Placidi F, Romigi A, Zannino S, et al. Cognitive profile and brain morphological changes in obstructive sleep apnea. Neuroimage (2011) 54:787-93. doi:10.1016/j.neuroimage.2010.09.065.
18. Macey PM, Kumar R, Yan-Go FL, Woo MA, Harper RM. Sex differences in white matter alterations accompanying obstructive sleep apnea. Sleep (2012) 35:1603-13. doi:10.5665/sleep.2228.
19. Farre R, Hernandez L, Montserrat JM, Rotger M, Ballester E, Navajas D. Sham continuous positive airway pressure for placebo-controlled studies in sleep apnea. Lancet (1999) 353:1154. doi:10.1016/S0140-6736(99)01056-9.
20. AASM. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications. Westchester, IL: American Academy of Sleep Medicine (AASM) (2007).
21. Good CD, Johnsrude IS, Ashburner J, Henson RN, Friston KJ, Frackowiak RS. A voxel-based morphometric study of ageing in 465 normal adult human brains. Neuroimage (2001) 14:21-36. doi:10.1006/nimg.2001.0786.
22. Mechelli A, Price CJ, Friston KJ, Ashburner J. Voxel-based morphometry of the human brain: methods and applications. Curr Med Imaging Rev (2005) 1:105-13. doi:10.2174/1573405054038726.
23. Morrell MJ, Twigg G. Neural consequences of sleep disordered breathing: the role of intermittent hypoxia. Adv Exp Med Biol (2006) 588:75-88. doi:10.1007/978-0-387-34817-9_8.
24. Yaouhi K, Bertran F, Clochon P, Mezenge F, Denise P, Foret J, et al. A combined neuropsychological and brain imaging study of obstructive sleep apnea. J Sleep Res (2009) 18:36-48. doi:10.1111/j.1365-2869.2008.00705.x.
25. Morrell MJ, Jackson ML, Twigg GL, Ghiassi R, McRobbie DW, Quest RA, et al. Changes in brain morphology in patients with obstructive sleep apnea. Thorax (2010) 65:908-14. doi:10.1136/thx.2009.126730.
26. Meerlo P, Mistlberger RE, Jacobs BL, Heller HC, McGinty D. New neurons in the adult brain: the role of sleep and consequences of sleep loss. Sleep Med Rev (2009) 13:187-94. doi:10.1016/j.smrv.2008.07.004.
27. Alchanatis M, Zias N, Deligiorgis N, Amfilochiou A, Dionellis G, Orphanidou D. Sleep apnea-related cognitive deficits and intelligence: an implication of cognitive reserve theory. J Sleep Res (2005) 14:69-75. doi:10.1111/j.1365-2869.2004.00436.x.