In vivo toxicity evaluation of the migration extract of an organomodified clay-poly(lactic) acid nanocomposite

Journal of Toxicology and Environmental Health - Part A: Current Issues

Volumn 77, Issue 13, 2014, Pages 731-746

  Maisanaba, Sara ^a   Gutiérrez Praena, Daniel ^a   Puerto, María ^a   Llana Ruiz Cabello, María ^a   Pichardo, Silvia ^a   Moyano, Rosario ^b   Blanco, Alfonso ^b   Jordá Beneyto, María ^c   Jos, Ángeles ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

^b UNIVERSITY OF CÓRDOBA   (Spain)

^c ITENE (Packaging Transport and Logistics Research Institute)   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CATALASE; GLUTATHIONE; GLUTATHIONE DISULFIDE; INTERLEUKIN 6; MONTMORILLONITE; NANOCOMPOSITE; POLYLACTIC ACID; SUPEROXIDE DISMUTASE; BENTONITE; BIOLOGICAL MARKER; LACTIC ACID; POLYMER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEVERAGE; BODY WEIGHT; CLAY; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FOOD INDUSTRY; FOOD PACKAGING; GENE EXPRESSION; HISTOPATHOLOGY; IN VIVO STUDY; INFLAMMATION; LIPID PEROXIDATION; MALE; MICROSCOPY; NONHUMAN; ORGAN WEIGHT; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SAFETY; TOXICITY TESTING; WEIGHT GAIN; WESTERN BLOTTING; ANIMAL; CHEMISTRY; DRUG EFFECTS; FOOD STORAGE; FRACTIONATION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PROCEDURES; TOXICITY; WISTAR RAT;

ANIMALS; BENTONITE; BIOLOGICAL MARKERS; CHEMICAL FRACTIONATION; FOOD STORAGE; GENE EXPRESSION REGULATION; INTERLEUKIN-6; LACTIC ACID; MALE; NANOCOMPOSITES; OXIDATIVE STRESS; POLYMERS; RATS; RATS, WISTAR;

EID: 84900990385     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287394.2014.890987     Document Type: Article

References (37)

1. Alfadul, S. M., and, Elneshwy, A.A. 2010. Use of the nanotechnology in food processing, packaging and safety-Review. Afr. J. Food Agric. Nutr. Dev. 10: 2719-2739.
2. Arora, A., and, Padua, G. W. 2010. Review: Nanocomposites in food packaging. J. Food Sci. 75: 43-49.
3. Baek, M., Lee, J., and, Cho, S. 2012. Toxicological effects of a cationic clay, montmorillonite in vitro and in vivo. Mol. Cell. Toxicol. 8: 95-101.
4. Beers, R. F., and, Sizer, I. W. 1952. A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase. J. Biol. Chem. 195: 133-140.
5. Betega de Paiva, L., Morales, A. R., and, Valenzuela-Díaz, F. R. 2008. Organoclays: properties, preparation and applications. Appl. Clay Sci. 42: 8-24.
6. Bouwmeester, H., Dekkers, S., Noordan, M. Y., Hagens, W. I., Bulder, A. S., de Heer, C., Ten Voorde, S. C. E. G., Wijnhiven, S. W. P., Marvin, H. J. P., and, Sips, A. J. A. M. 2009. Review of health safety aspects of nanotechnologies in food production. Regul. Toxicol. Pharmacol. 53: 52-62.
7. Bradford, M. 1976. A rapid sensitive method for quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72: 248-254.
8. Bradley, E. L., Castle, L., and, Chaundry, Q. 2011. Applications of nanomaterials in food packaging with a consideration of opportunities for developing countries. Trends Food Sci. Technol. 22: 604-610.
9. Ellenbecker, M., and, Tsai, S. 2011. Engineered nanoparticles: Safer substitutes for toxic materials, or a new hazard? J. Clean. Prod. 19: 483-487.
10. Esterbauer, H., and, Cheeseman, K.H. 1990. Determination of aldehydic lipid peroxidation products: Malonaldehyde and 4-hydroxynonenal. Methods Enzymol. 186: 407-421. (Pubitemid 20279982)
11. European Food Security Authority. 2011. Guidance on risk assessment of the application of nanoscience and nanotechnologies in the food and feed chain. EFSA J. 9: 2140.
12. European Union. 1982. Council Directive 82/711/EEC. The basic rules necessary for testing migration of the constituents of plastic materials and articles to come into contact with foodstuffs. Off. J. Eur. Union. 297: 26-30.
13. European Union. 2011. Commission Regulation (EU) No 10/2011 of 14 January 2011 on plastic materials and articles intended to come into contact with food. Off. J. Eur. Union. 12: 1-89.
14. Gutiérrez-Praena, D., Jos, A., Pichardo, S., Puerto, M., and, Cameán, A. M. 2013. Influence of the exposure way and the time of sacrifice on the effects induced by a single dose of pure cylindrospermopsin on the activity and transcription of glutathione peroxidase and glutathione-S -transferase enzymes in tilapia (Oreochromis niloticus). Chemosphere 90: 986-992.
15. Habig, W. H., Pabst, M. J., and, Jakoby, W. B. 1974. Glutathione S -transferase. The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 249: 7130-7139.
16. Hatzigrigoriou, N. B., and, Papaspyrides, C. D. 2011. Nanotechnology in plastic food-contact materials. J. Appl. Polymer Sci. 122: 3720-3739.
17. Houtman, J., Maisanaba, S., Puerto, M., Gutiérrez-Praena, D., Jordá, M., Aucejo, S., and, Jos, A. 2014. Toxicity assessment of organomodified clays used in food contact materials on human target cell lines. Appl. Clay Sci. 90: 150-158.
18. Jordá-Beneyto, M., Ortuño, N., Devis, A., Aucejo, S., Puerto, M., Gutiérrez-Praena, D., Houtman, J., Pichardo, S., Maisanaba, S., and, Jos, A. 2013. Use of nanoclay platelets in food packaging materials: technical and cytotoxicity approach. Food Addit. Contam. A. 3: 354-363. doi:10.1080/19440049.2013.874045.
19. Lawrence, A., and, Burk, R. F. 1976. Glutathione peroxidase activity in selenium deficient rat liver. Biochem. Biophys. Res. Commun. 71: 952-958.
20. Li, P. R., Wei, J. C., Chiu, Y. F., Su, H. L., Peng, F. C., and, Lin, J. J. 2010. Evaluation on cytotoxicity and genotoxicity of the exfoliated silicate nanoclay. Appl. Mater. Interfaces. 2: 1608-1613.
21. Lordan, S., Kennedy, J. E., and, Higginbothamb, C. L. 2011. Cytotoxic effects induced by unmodified and organically modified nanoclays in the human hepatic HepG2 cell line. J. Appl. Toxicol. 31: 27-35.
22. Maisanaba, S., Puerto, M., Pichardo, S., Jordá, M., Moreno, F. J., Aucejo, S., and, Jos, A. 2013a. In vitro toxicological assessment of clays for their use in food packaging applications. Food Chem. Toxicol. 57: 266-275.
23. Maisanaba, S., Gutiérrez-Praena, D., Pichardo, S., Moreno, F. J., Jordá, M., Cameán, A. M., Aucejo, S., and, Jos, A. 2013b. Toxic effects of a modified montmorillonite clay on the human intestinal cell line Caco-2. J. Appl. Toxicol. doi: 10.1002/jat.2945.
24. Maisanaba, S., Pichardo, S., Jordá-Beneyto, M., Aucejo, S., Cameán, A. M., and, Jos, A. 2014a. Cytotoxicity and mutagenicty studies on migration extracts from nanocomposites with potential use in food packaging. Food Chem. Toxicol. 66: 366-372.
25. Maisanaba, S., Puerto, M., Gutiérrez-Praena, D., Llana-Ruíz-Cabello, M., Pichardo, S., Mate, A., Jordá-Beneyto, M., Cameán, A. M., Aucejo, S., and, Jos, A. 2014b. In vivo evaluation of activities and expression of antioxidant enzymes in Wistar rats exposed for 90 days to a modified clay. J. Toxicol. Environ. Health A. 77: 456-466.
26. Maisanaba, S., Gutiérrez-Praena, D., Puerto, M., Moyano, R., Blanco, A., Jordá, M., Cameán, A. M., Aucejo, S., and, Jos, A. 2014c. Effects of the subchronic exposure to organomodified clay for food packaging applications on Wistar rats. Appl. Clay Sci. In press.
27. Markarian, J. 2005. Automotive and packaging offer growth opportunities for nancomposites. Plastics Addit. Compound. 7: 18-21. (Pubitemid 43003705)
28. Mascolo, N., Summa, V., and, Tateo, F. 1999. Characterization of toxic elements in clays for human healing use. Appl. Clay Sci. 15: 491-500. (Pubitemid 30075809)
29. Mascolo, N., Summa, V., and, Tateo, F. 2004. In vivo experimental data on the mobility of hazardous chemical elements from clays. Appl. Clay Sci. 25: 23-28. (Pubitemid 38300723)
30. Matthews, F. L., and, Rawlings, R. D. 1999. Composite materials: Engineering and science. London, UK: Woodhead Publishing.
31. McCord, J. M., and, Fridovich, I. 1969. Superoxide dismutase. An enzymic function forerythrocuprein (hemocuprein). J. Biol. Chem. 244: 6049-6055.
32. Neethirajan, S., and, Jayas, D. S. 2011. Nanotechnology for the food and bioprocessing industries. Food Bioprocess Technol. 4: 39-47.
33. Nielsen, L. E. 1967. Models for the permeability of filled polymer systems. J. Macromol. Sci. Chem. 1: 929-942.
34. Roco, M. C. 2002. Nanoscale science and engineering for agriculture and food systems. Washington, DC: National Planning Workshop, USDA/CSREES.
35. Sharma, A. K., Schmidt, B., Frandsen, H., Jacobsen, N. R., Larsen, E. H., and, Binderup, M. L. 2010. Genotoxicity of unmodified 687 and organo-modified montmorillonite. Mutat. Res. 700: 18-25.
36. Sorrentino, A., Gorrasi, G., and, Vittoria, V. 2007. Potential perspectives of bio-nanocomposites for food packaging applications. Trends Food Sci. Technol. 18: 84-95. (Pubitemid 46136905)
37. Yoshida, T., Yoshioka, Y., Matsuyama, K., Nakazato, Y., Tochigi, S., Hirai, T., Kondoh, S., Nagano, K., Abe, Y., Kamada, H., Tsunoda, S., Nabeshi, H., Yoshikawa, T., and, Tsutsumi, Y. 2012. Surface modification of amorphous nanosilica particles suppresses nanosilica-induced cytotoxicity, ROS generation, and DNA damage in various mammalian cells. Biochem. Biophys. Res. Commun. 427: 748-752.