Process development of Lappula squarrosa oil refinement: Monitoring of pyrrolizidine alkaloids in boraginaceae seed oils

JAOCS, Journal of the American Oil Chemists' Society

Volumn 91, Issue 5, 2014, Pages 721-731

  Cramer, Luise ^a   Fleck, Gunther ^b   Horn, Gert ^c   Beuerle, Till ^a  

^a TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

^b Pilot Pflanzenoeltechnologie Magdeburg E V PPM   (Germany)

^c Exsemine GmbH   (Germany)

Author keywords

Boraginaceous seed oils; Borago officinalis; Echium spp.; Food supplements; HPLC ESI MS MS; Lappula squarrosa; Oil refinement; Pyrrolizidine alkaloids

Indexed keywords

ALKALOIDS; METABOLITES; NITROGEN COMPOUNDS; ODOR CONTROL; POLYUNSATURATED FATTY ACIDS; WASHING;

BORAGO OFFICINALIS; ECHIUM SPP; FOOD SUPPLEMENTS; HPLC-ESI-MS/MS; LAPPULA SQUARROSA; OIL REFINEMENT; PYRROLIZIDINE ALKALOID; SEED OIL;

OILS AND FATS;

BORAGINACEAE; BORAGO; BORAGO OFFICINALIS; ECHIUM; LAPPULA SQUARROSA;

EID: 84900875349     PISSN: 0003021X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11746-014-2426-1     Document Type: Article

References (25)

1. EFSA Panel on Dietetic Products, Nutrition, and Allergies (NDA) (2010) Scientific opinion on dietary reference values for fats, including saturated fatty acids, polyunsaturated fatty acids, monounsaturated fatty acids, trans fatty acids, and cholesterol. EFSA J 8:1461-1568. http://www.efsa.europa.eu/de/ efsajournal/pub/1461.htm. Accessed 12 Sept 2013
2. Harizi H, Corcuff JB, Gualde N (2008) Arachidonic-acid-derived eicosanoids: roles in biology and immunopathology. Trends Mol Med 14:461-469
3. Komprda T (2012) Eicosapentaenoic and docosahexaenoic acids as inflammation-modulating and lipid homeostasis influencing nutraceuticals: a review. J Funct Food 4:25-38
4. DEG, Evidenzbasierte Leitlinie, Fettkonsum und Prävention ausgewählter ernährungsmitbedingter Krankheiten, 2006. http://www.dge.de/pdf/ws/ll-fett/DGE-Leitlinie-Fett-11-2006.pdf. Accessed 12 Sept 2013
5. SOFA Database on Seed Oil Fatty Acids. http://sofa.mri.bund.de/. Accessed 12 Sept 2013
6. James MJ, Ursin VM, Cleland LG (2003) Metabolism of stearidonic acid in human subjects: comparison with the metabolism of other n-3 fatty acids. Am J Clin Nutr 77:1140-1145
7. Whelan J (2009) Dietary stearidonic acid is a long chain (n-3) polyunsaturated fatty acid with potential health benefits. J Nutr 139:5-10
8. Whelan J, Gouffon J, Zhao Y (2001) Effects of dietary stearidonic acid on biomarkers of lipid metabolism. J Nutr. doi: 10.3945/jn.111.149138, 1S-5S
9. Surette ME (2013) Dietary omega-3 PUFA and health: stearidonic acid-containing seed oils as effective and sustainable alternatives to traditional marine oils. Mol Nutr Food Res 57:748-759
10. Hammond BG, Lemen JK, Ahmed G, Miller KD, Kirkpatrick J, Fleeman T (2008) Safety assessment of SDA soybean oil: results of a 28-day gavage study and a 90-day/one generation reproduction feeding study in rats. Regul Toxicol Pharmacol 52:311-323
11. Commission Decision (2008) Authorising the placing on the market of refined echium oil as novel food ingredient under Regulation (EC) No. 258/97 of the European Parliament and of the Council (notified under document number C(2008) 3049; (2008/558/EC). http://eur-lex.europa.eu/LexUriServ/LexUriServ.do? uri=OJ:L:2008:180:0017:0019:EN:PDF. Accessed 12 Sept 2013
12. Özcan T (2008) Analysis of the total oil and fatty acid composition of seeds of some Boraginaceae taxa from Turkey. Plant Syst Evol 274:143-153
13. Guil-Guerrero JL, Rincón-Cervera MA, Gómez-Mercado F, Ramos-Bueno RP, Venegas-Venegas E (2013) New seed oils of Boraginaceae rich in stearidonic and gamma-linolenic acids from the Maghreb region. J Food Compos Anal 31:20-23
14. Hartmann T, Witte L (1995) Pyrrolizidine alkaloids: chemical, biological and chemoecological aspects. In: Pelletier SW (ed) Alkaloids: chemical and biological perspectives, vol 9. Pergamon Press, Oxford, pp 155-233
15. EFSA (2011) Scientific opinion on pyrrolizidine alkaloids in food and feed. EFSA J 9. doi: 10.2903/j.efsa. http://www.efsa.europa.eu/de/efsajournal/ pub/2406.htm. Accessed 12 Sept 2013
16. Hegi G (1927) Illustrierte Flora von Mittel-Europa. Band V/3, Carl Hanser München, 2138-2142 and 2220-2228
17. Craig BM, Bhatty MK (1964) A naturally occurring all-cis 6,9,12,15-octadecatetraenoic acid in plant oils. JAOCS 41:209-211
18. Gunstone FD, Hamilton RJ, Padley FB, Qureshi MI (1965) Glyceride studies. V. The distribution of unsaturated acyl groups in vegetable triglycerides. JAOCS 42:965-970
19. Guil-Guerrero JL (2007) Stearidonic acid (18:4n-3): metabolism, nutritional importance, medical uses and natural sources. Eur J Lipid Sci Technol 109:1226-1236
20. Khatmulina LI, Fedorov NI, Ermolaeva NA, Galkin EG, Yunusov MS (2012) Polyunsaturated fatty acids from several plant species of the family Boraginaceae. Chem Nat Compd 48:361-366
21. Cramer L, Schiebel H-M, Ernst L, Beuerle T (2013) Pyrrolizidine alkaloids in the food chain: development, validation, and application of a new HPLC-ESI-MS/MS sum parameter method. J Agric Food Chem 61:11382-11391
22. Kempf M, Reinhard A, Beuerle T (2010) Pyrrolizidine alkaloids (PAs) in honey and pollen-legal regulation of PA levels in food and animal feed required. Mol Nutr Food Res 54:158-168
23. Cramer L, Beuerle T (2012) Detection and quantification of pyrrolizidine alkaloids in antibacterial medical honeys. Planta Med 78:1976-1982
24. Mierendorff HJ (1995) Determination of pyrrolizidine alkaloids by thin-layer-chromatography in the oil of seeds of Borago officinalis L. Lipid 97:33-37
25. Wretensjö I, Karlberg B (2003) Pyrrolizidine alkaloid content in crude and processed borage oil from different processing stages. JAOCS 80:963-970